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Kat Arney
Katharine Luisa Arney is a British science communicator, broadcaster, author, and the founder and creative director of communications consultancy First Create the Media. She was a regular co-host of ''The Naked Scientists'', a BBC Radio programme and podcast, and also hosted the BBC Radio 5 Live ''Science Show'' and the BBC Radio 4 series ''Did the Victorians Ruin the World'' She has written numerous articles and columns for ''Science'', ''The Guardian'', ''New Scientist'' the BBC and others. Education Arney was educated at the University of Cambridge where she was awarded a PhD in 2002 for research into epigenetic modification in the mouse zygote and regulation of imprinted genes. Her PhD was supervised by Azim Surani and included research on Insulin-like growth factor 2 and the H19 gene. She went on to do postdoctoral research at Imperial College London working in the laboratory of Amanda Fisher. Career Arney is a strong advocate for involvement of women in science, techn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer Research
Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments. These applications include surgery, radiation therapy, chemotherapy, hormone therapy, immunotherapy and combined treatment modalities such as chemo-radiotherapy. Starting in the mid-1990s, the emphasis in clinical cancer research shifted towards therapies derived from biotechnology research, such as cancer immunotherapy and gene therapy. Cancer research is done in academia, research institutes, and corporate environments, and is largely government funded. History Cancer research has been ongoing for centuries. Early research focused on the causes of cancer. Percivall Pott identified the first environmental trigger (chimney soot) for cancer in 1775 and cigarette smoking was identif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epigenetic
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression can ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Publishers Weekly
''Publishers Weekly'' (''PW'') is an American weekly trade news magazine targeted at publishers, librarians, booksellers, and literary agents. Published continuously since 1872, it has carried the tagline, "The International News Magazine of Book Publishing and Bookselling". With 51 issues a year, the emphasis today is on book reviews. The magazine was founded by bibliographer Bibliography (from and ), as a discipline, is traditionally the academic study of books as physical, cultural objects; in this sense, it is also known as bibliology (from ). English author and bibliographer John Carter describes ''bibliography ... Frederick Leypoldt in the late 1860s, and had various titles until Leypoldt settled on the name ''The Publishers' Weekly'' (with an apostrophe) in 1872. The publication was a compilation of information about newly published books, collected from publishers and from other sources by Leypoldt, for an audience of booksellers. By 1876, ''The Publishers' Weekly ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bloomsbury Publishing
Bloomsbury Publishing plc is a British worldwide publishing house of fiction and non-fiction. It is a constituent of the FTSE SmallCap Index. Bloomsbury's head office is located in Bloomsbury, an area of the London Borough of Camden. It has a US publishing office located in New York City, an India publishing office in New Delhi, an Australia sales office in Sydney CBD and other publishing offices in the UK including in Oxford. The company's growth over the past two decades is primarily attributable to the ''Harry Potter'' series by J. K. Rowling and, from 2008, to the development of its academic and professional publishing division. The Bloomsbury Academic & Professional division won the Bookseller Industry Award for Academic, Educational & Professional Publisher of the Year in both 2013 and 2014. Divisions Bloomsbury Publishing group has two separate publishing divisions—the Consumer division and the Non-Consumer division—supported by group functions, namely Sales and Mar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ernest Hemingway
Ernest Miller Hemingway (July 21, 1899 – July 2, 1961) was an American novelist, short-story writer, and journalist. His economical and understated style—which he termed the iceberg theory—had a strong influence on 20th-century fiction, while his adventurous lifestyle and public image brought him admiration from later generations. Hemingway produced most of his work between the mid-1920s and the mid-1950s, and he was awarded the 1954 Nobel Prize in Literature. He published seven novels, six short-story collections, and two nonfiction works. Three of his novels, four short-story collections, and three nonfiction works were published posthumously. Many of his works are considered classics of American literature. Hemingway was raised in Oak Park, Illinois. After high school, he was a reporter for a few months for ''The Kansas City Star'' before leaving for the Italian Front (World War I), Italian Front to enlist as an ambulance driver in World War I. In 1918, he was se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Times Educational Supplement
''Tes'', formerly known as the ''Times Educational Supplement'', is a weekly UK publication aimed at education professionals. It was first published in 1910 as a pull-out supplement in ''The Times'' newspaper. Such was its popularity that in 1914, the supplement became a separate publication selling for one penny. ''TES'' focuses on school-related news and features. It covered higher education until the ''Times Higher Education Supplement'' (now ''Times Higher Education'') was launched as a sister publication in 1971. Today its editor is Jon Severs. Since 1964, an alternative version of the publication, ''TESS'', has been produced for Scotland. An edition for Wales, ''TES Cymru'', was also published between 2004 and 2011. The lack of content about Wales since its closure has been criticised by the Welsh Education Minister, Jeremy Miles. All are produced by London-based company TES Global, which has been owned by US investment firm Providence Equity Partners LLC since 2018. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science, Technology, Engineering, And Mathematics
Science, technology, engineering, and mathematics (STEM) is an umbrella term used to group together the distinct but related technical disciplines of science, technology, engineering, and mathematics. The term is typically used in the context of education policy or curriculum choices in schools. It has implications for workforce development, national security concerns (as a shortage of STEM-educated citizens can reduce effectiveness in this area) and immigration policy. There is no universal agreement on which disciplines are included in STEM; in particular whether or not the ''science'' in STEM includes social sciences, such as psychology, sociology, economics, and political science. In the United States, these are typically included by organizations such as the National Science Foundation (NSF), which deals with all matters concerning science and new discoveries in science as it affects development, research, and innovations, the Department of Labor's O*Net online database for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Cell Science
The ''Journal of Cell Science'' (formerly the ''Quarterly Journal of Microscopical Science'') is a peer-reviewed scientific journal in the field of cell biology. The journal is published by The Company of Biologists. The journal is partnered with Publons, is part of the Review Commons initiative and has two-way integration with bioRxiv. ''Journal of Cell Science'' is a hybrid journal and publishes 24 issues a year. Content over 6 months old is free to read. History Foundation and early years The journal was established in 1853 as the ''Quarterly Journal of Microscopical Science'' (''Q. J. Microsc. Sci.'', ). The founding editors were Edwin Lankester and George Busk.''Quarterly Journal of Microscopical Science'' 1(1), front matter (accessed 18 April 2008) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H19 (gene)
H19 is a gene for a long noncoding RNA, found in humans and elsewhere. H19 has a role in the negative regulation (or limiting) of body weight and cell proliferation. This gene also has a role in the formation of some cancers and in the regulation of gene expression. . The H19 gene is expressed exclusively on one parental allele in a phenomenon known as imprinting. H19 is only transcribed from the maternally inherited allele; the paternal H19 allele is not expressed. H19 was first named ASM (for Adult Skeletal Muscle) because of its expression in adult skeletal muscle ("ASM") in rats. H19 is also known as BWS because aberrant H19 expression can be involved in Beckwith-Wiedemann Syndrome ("BWS"), as well as Silver-Russell syndrome. Epigenetics deregulations at H19 imprinted gene in sperm have been observed associated with male infertility. Gene characterization The H19 gene contains 3 Sp1 binding sites, however these 3 sites are present in a part of the sequence that has shown ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
