Jules Freund
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Jules Freund
Jules Freund (June 24, 1890 – April 22, 1960) was a Hungarian born American immunologist, most famous for the Freund's adjuvant. According to the ''Journal of Immunology'', "Jules (Julius) Freund studied in Budapest at the Royal Hungarian University. After receiving the degree of M.D. at the age of 23, he served as Medical Interne in the Austrian Army (1913–1914) and was attached to the Department of Hygiene at the University as Assistant. Following the outbreak of war in 1914, he saw service in the Austrian Army and returned to the University in Budapest as Commissioner for Hygiene in the army. He held the post of assistant professor in Preventive Medicine, earning the Certificate of Public Health in 1920. In 1922 he went to Hamburg, working in the Department of Hygiene at the Medical School." In 1942, Jules Freund and Katherine McDermott published a paper on their experiments on immunization of guinea pigs with horse serum containing killed tubercle bacilli and adjuva ...
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Hungarians
Hungarians, also known as Magyars ( ; hu, magyarok ), are a nation and  ethnic group native to Hungary () and historical Hungarian lands who share a common culture, history, ancestry, and language. The Hungarian language belongs to the Uralic language family. There are an estimated 15 million ethnic Hungarians and their descendants worldwide, of whom 9.6 million live in today's Hungary. About 2–3 million Hungarians live in areas that were part of the Kingdom of Hungary before the Treaty of Trianon in 1920 and are now parts of Hungary's seven neighbouring countries, Slovakia, Ukraine, Romania, Serbia, Croatia, Slovenia, and Austria. Significant groups of people with Hungarian ancestry live in various other parts of the world, most of them in the United States, Canada, Germany, France, the United Kingdom, Chile, Brazil, Australia, and Argentina. Hungarians can be divided into several subgroups according to local linguistic and cultural characteristics; subgroups with distinc ...
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Freund's Adjuvant
Freund's adjuvant is a solution of antigen emulsified in mineral oil and used as an immunopotentiator (booster). The complete form, Freund's Complete Adjuvant (FCA or CFA) is composed of inactivated and dried mycobacteria (usually '' M. tuberculosis''), whereas the incomplete form (FIA or IFA) lacks the mycobacterial components (hence just the water in oil emulsion). It is named after Jules T. Freund. Regulation Freund's complete adjuvant is effective in stimulating cell-mediated immunity and leads to potentiation of T helper cells that leads to the production of certain immunoglobulins and effector T cells. Its use in humans is forbidden by regulatory authorities, due to its toxicity. Even for animal research there are currently guidelines associated with its use, due to its painful reaction and potential for tissue damage. Injections of FCA should be subcutaneous or intraperitoneal, because intradermal injections may cause skin ulceration and necrosis; intramuscular injections m ...
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Budapest
Budapest (, ; ) is the capital and most populous city of Hungary. It is the ninth-largest city in the European Union by population within city limits and the second-largest city on the Danube river; the city has an estimated population of 1,752,286 over a land area of about . Budapest, which is both a city and county, forms the centre of the Budapest metropolitan area, which has an area of and a population of 3,303,786; it is a primate city, constituting 33% of the population of Hungary. The history of Budapest began when an early Celtic settlement transformed into the Roman town of Aquincum, the capital of Lower Pannonia. The Hungarians arrived in the territory in the late 9th century, but the area was pillaged by the Mongols in 1241–42. Re-established Buda became one of the centres of Renaissance humanist culture by the 15th century. The Battle of Mohács, in 1526, was followed by nearly 150 years of Ottoman rule. After the reconquest of Buda in 1686, the ...
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Hamburg
(male), (female) en, Hamburger(s), Hamburgian(s) , timezone1 = Central (CET) , utc_offset1 = +1 , timezone1_DST = Central (CEST) , utc_offset1_DST = +2 , postal_code_type = Postal code(s) , postal_code = 20001–21149, 22001–22769 , area_code_type = Area code(s) , area_code = 040 , registration_plate = , blank_name_sec1 = GRP (nominal) , blank_info_sec1 = €123 billion (2019) , blank1_name_sec1 = GRP per capita , blank1_info_sec1 = €67,000 (2019) , blank1_name_sec2 = HDI (2018) , blank1_info_sec2 = 0.976 · 1st of 16 , iso_code = DE-HH , blank_name_sec2 = NUTS Region , blank_info_sec2 = DE6 , website = , footnotes ...
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Albert Lasker Award For Basic Medical Research
The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Medicine; almost 50% of the winners have gone on to win one. List of Albert Lasker Award for Basic Medical Research recipients {, , Valign="top", {, class="wikitable" ! Year !! Recipient , - , Rowspan="3", 2022 , , Richard O. Hynes , - , , Erkki Ruoslahti , - , , Timothy A. Springer , - , Rowspan="3", 2021 , , Karl Deisseroth , - , , Peter Hegemann , - , , Dieter Oesterhelt , - , Rowspan="1", 2020 , , not awarded   , - , Rowspan="2", 2019 , , Max Dale Cooper , - , , Jacques Miller , - , Rowspan="2", 2018 , , C. David Allis , - , , Michael Grunstein , - , Rowspan="1", 2017 , , Michael N. Hall , - , Rowspan="3", 2016 , , William Kaelin, Jr. , - , , Peter J. Ratcliffe , - , , Gregg L. Semenza , - , R ...
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Albert Coons
Albert Hewett Coons (June 28, 1912 – September 30, 1978) was an American physician, pathologist, and immunologist. He was the first person to conceptualize and develop immunofluorescent techniques for labeling antibodies in the early 1940s. Early years Coons was born in Gloversville, New York, on June 28, 1912, the son of Albert Selmser and Marion (née Hewett) Coons. His father was the president of a glove-manufacturing company, and his grandfather, Eugene Coons, was a physician. He was educated in Gloversville public schools, graduated with a B.S. from Williams College (Williamstown, Massachusetts) in 1933, and received his M.D. degree from Harvard Medical School in 1937.McDevitt, H. OAlbert Hewett Coons ''Biographical memoirs of the National Academy of Sciences. Thereafter, Albert pursued residency training in internal medicine at Massachusetts General Hospital in Boston, Massachusetts. During the final years of his house-officership, Coons joined the Thorndike Memo ...
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American Immunologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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1890 Births
Year 189 ( CLXXXIX) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Silanus and Silanus (or, less frequently, year 942 ''Ab urbe condita''). The denomination 189 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Plague (possibly smallpox) kills as many as 2,000 people per day in Rome. Farmers are unable to harvest their crops, and food shortages bring riots in the city. China * Liu Bian succeeds Emperor Ling, as Chinese emperor of the Han Dynasty. * Dong Zhuo has Liu Bian deposed, and installs Emperor Xian as emperor. * Two thousand eunuchs in the palace are slaughtered in a violent purge in Luoyang, the capital of Han. By topic Arts and sciences * Galen publishes his ''"Treatise on the various temperaments"'' (aka ''O ...
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1960 Deaths
Year 196 ( CXCVI) was a leap year starting on Thursday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Dexter and Messalla (or, less frequently, year 949 ''Ab urbe condita''). The denomination 196 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Emperor Septimius Severus attempts to assassinate Clodius Albinus but fails, causing Albinus to retaliate militarily. * Emperor Septimius Severus captures and sacks Byzantium; the city is rebuilt and regains its previous prosperity. * In order to assure the support of the Roman legion in Germany on his march to Rome, Clodius Albinus is declared Augustus by his army while crossing Gaul. * Hadrian's wall in Britain is partially destroyed. China * First year of the '' Jian'an era of the Chinese Han Dynasty. * Emperor Xian o ...
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