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Joseph H. Burchenal
Joseph Holland Burchenal (December 21, 1912 – March 8, 2006) was an American oncologist, and a winner of the 1972 Albert Lasker Award for Medical Research for his work on developing a chemotherapy for Burkitt's lymphoma.Staff, ASCO. February 24, 201Oncology Luminaries: Dr. Joseph Burchenal (1912-2006)/ref> His research with George Hitchings and Gertrude Elion led to the creation of the leukemia treatment mercaptopurine. He worked at Memorial Sloan Kettering Cancer Center and was a member of the presidential panel that initiated the U.S. federal government's War on Cancer. Burchenal died in Hanover, New Hampshire Hanover is a town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Eng ... on March 8, 2006. He was 93 years old.Jeremy Pearce for the ''New York Times''. March 16, 200Dr. Joseph H. Burchenal, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oncologist
Oncology is a branch of medicine that deals with the study, treatment, diagnosis and prevention of cancer. A medical professional who practices oncology is an ''oncologist''. The name's etymological origin is the Greek word ὄγκος (''ónkos''), meaning "tumor", "volume" or "mass". Oncology is concerned with: * The diagnosis of any cancer in a person (pathology) * Therapy (e.g. surgery, chemotherapy, radiotherapy and other modalities) * Follow-up of cancer patients after successful treatment * Palliative care of patients with terminal malignancies * Ethical questions surrounding cancer care * Screening efforts: ** of populations, or ** of the relatives of patients (in types of cancer that are thought to have a hereditary basis, such as breast cancer) Diagnosis Medical histories remain an important screening tool: the character of the complaints and nonspecific symptoms (such as fatigue, weight loss, unexplained anemia, fever of unknown origin, paraneoplastic phenomena ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lasker Award
The Lasker Awards have been awarded annually since 1945 to living persons who have made major contributions to medical science or who have performed public service on behalf of medicine. They are administered by the Lasker Foundation, which was founded by Albert Lasker and his wife Mary Woodard Lasker (later a medical research activist). The awards are sometimes referred to as "America's Nobels". The Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize. Eighty-six Lasker laureates have received the Nobel Prize, including 32 in the last two decades. Claire Pomeroy is the current president of the Lasker Foundation. Award The award is given in four branches of medical science: # Albert Lasker Basic Medical Research Award # Lasker-DeBakey Clinical Medical Research Award # Lasker-Bloomberg Public Service Award (Renamed in 2011 from Mary Woodard Lasker Public Service Award. Renamed in 2000 from Albert Lasker Public Service Award.) # ''Lasker-Koshl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Burkitt's Lymphoma
Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. The overall cure rate for Burkitt lymphoma in developed countries is about 90%, and it is worse in low-income countries. Burkitt lymphoma is uncommon in adults, in whom it has a worse prognosis. Classification Burkitt lymphoma can be divided into three main clinical variants: the endemic, the sporadic, and the immunodeficiency-associated variants. By morphology (i.e., microscopic appearance), immunophenotype, and genetics, the variants of Burkitt lymphoma are alike. * The endemic variant (also called "African variant") most commonly occurs in children living in malaria-endemic regions of the world (e.g., equatorial Africa, Brazil, and Papua New Guinea). Epstein–Barr virus (EBV) infection is found in nearly all patients. Chronic mala ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Hitchings
George Herbert Hitchings (April 18, 1905 – February 27, 1998) was an American medical doctor who shared the 1988 Nobel Prize in Physiology or Medicine with Sir James Black and Gertrude Elion "for their discoveries of important principles for drug treatment", Hitchings specifically for his work on chemotherapy. Education and early life Hitchings was born in Hoquiam, Washington, in 1905, and grew up there, in Berkeley, California, San Diego, Bellingham, Washington, and Seattle. He graduated from Seattle's Franklin High School, where he was salutatorian, in 1923, and from there went to the University of Washington, from which he graduated with a degree in chemistry ''cum laude'' in 1927, after having been elected to Phi Beta Kappa as a junior the year before. That summer, he worked at the university's Puget Sound Biological Station at Friday Harbor on San Juan Islandbr> and received a master's degree the next year for his thesis based on that work. From the University of Washing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gertrude Elion
Gertrude "Trudy" Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, who shared the 1988 Nobel Prize in Physiology or Medicine with George H. Hitchings and Sir James Black for their use of innovative methods of rational drug design for the development of new drugs. This new method focused on understanding the target of the drug rather than simply using trial-and-error. Her work led to the creation of the anti-retroviral drug AZT, which was the first drug widely used against AIDS. Her well known works also include the development of the first immunosuppressive drug, azathioprine, used to fight rejection in organ transplants, and the first successful antiviral drug, acyclovir (ACV), used in the treatment of herpes infection. Early life and education Elion was born in New York City on January 23, 1918, to parents Robert Elion, a Lithuanian Jewish immigrant and a dentist, and Bertha Cohen, a Polish Jewish immigrant. Her family lost thei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mercaptopurine
Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis. For acute lymphocytic leukemia it is generally used with methotrexate. It is taken by mouth. Common side effects include bone marrow suppression, liver toxicity, vomiting, and loss of appetite. Other serious side effects include an increased risk of future cancer and pancreatitis. Those with a genetic deficiency in thiopurine S-methyltransferase are at higher risk of side effects. Use in pregnancy may harm the baby. Mercaptopurine is in the thiopurine and antimetabolite family of medications. Mercaptopurine was approved for medical use in the United States in 1953. It is on the World Health Organization's List of Essential Medicines. Medical uses It is used to treat acute lymphocytic leukemia, Crohn's d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute–designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue, between 67th and 68th streets, in Manhattan. According to U.S. News & World Report 2021-2022 Best Hospitals, Memorial Sloan Kettering Cancer Center (MSK) has been ranked as the number two hospital for cancer care in the nation. History New York Cancer Hospital (1884–1934) Memorial Hospital was founded on the Upper West Side of Manhattan in 1884 as the New York Cancer Hospital by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
War On Cancer
The "war on cancer" is the effort to find a cure for cancer by increased research to improve the understanding of cancer biology and the development of more effective cancer treatments, such as targeted drug therapies. The aim of such efforts is to eradicate cancer as a major cause of death. The signing of the National Cancer Act of 1971 by United States president Richard Nixon is generally viewed as the beginning of this effort, though it was not described as a "war" in the legislation itself. Despite significant progress in the treatment of certain forms of cancer (such as childhood leukemia), cancer in general remains a major cause of death half a century after this war on cancer began, leading to a perceived lack of progress and to new legislation aimed at augmenting the original National Cancer Act of 1971. New research directions, in part based on the results of the Human Genome Project, hold promise for a better understanding of the genetic factors underlying cancer, and th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hanover, New Hampshire
Hanover is a town located along the Connecticut River in Grafton County, New Hampshire, United States. As of the 2020 census, its population was 11,870. The town is home to the Ivy League university Dartmouth College, the U.S. Army Corps of Engineers Cold Regions Research and Engineering Laboratory, and Hanover High School. The Appalachian Trail crosses the town, connecting with a number of trails and nature preserves. Most of the population resides in the Hanover census-designated place (CDP)—the main village of the town. Located at the junctions of New Hampshire routes 10, 10A, and 120, the Hanover CDP recorded a population of 9,078 people at the 2020 census. The town also contains the smaller villages of Etna and Hanover Center. History Hanover was chartered by Governor Benning Wentworth on July 4, 1761, and in 1765–1766 its first European inhabitants arrived, the majority from Connecticut. Although the surface is uneven, the town developed into an agricultural co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elizabeth Burchenal
Elizabeth or Elisabeth may refer to: People * Elizabeth (given name), a female given name (including people with that name) * Elizabeth (biblical figure), mother of John the Baptist Ships * HMS ''Elizabeth'', several ships * ''Elisabeth'' (schooner), several ships * ''Elizabeth'' (freighter), an American freighter that was wrecked off New York harbor in 1850; see Places Australia * City of Elizabeth ** Elizabeth, South Australia * Elizabeth Reef, a coral reef in the Tasman Sea United States * Elizabeth, Arkansas * Elizabeth, Colorado * Elizabeth, Georgia * Elizabeth, Illinois * Elizabeth, Indiana * Hopkinsville, Kentucky, originally known as Elizabeth * Elizabeth, Louisiana * Elizabeth Islands, Massachusetts * Elizabeth, Minnesota * Elizabeth, New Jersey, largest city with the name in the U.S. * Elizabeth City, North Carolina * Elizabeth (Charlotte neighborhood), North Carolina * Elizabeth, Pennsylvania * Elizabeth Township, Pennsylvania (other) * Elizabeth, West Vi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1912 Births
Year 191 ( CXCI) was a common year starting on Friday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Apronianus and Bradua (or, less frequently, year 944 ''Ab urbe condita''). The denomination 191 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Parthia * King Vologases IV of Parthia dies after a 44-year reign, and is succeeded by his son Vologases V. China * A coalition of Chinese warlords from the east of Hangu Pass launches a punitive campaign against the warlord Dong Zhuo, who seized control of the central government in 189, and held the figurehead Emperor Xian hostage. After suffering some defeats against the coalition forces, Dong Zhuo forcefully relocates the imperial capital from Luoyang to Chang'an. Before leaving, Dong Zhuo orders his troops to loot the tombs of the H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2006 Deaths
File:2006 Events Collage V1.png, From top left, clockwise: The 2006 Winter Olympics open in Turin; Twitter is founded and launched by Jack Dorsey; The Nintendo Wii is released; Montenegro votes to declare independence from Serbia; The 2006 FIFA World Cup in Germany is won by Italy; Gol Transportes Aéreos Flight 1907 crashes in the Amazon rainforest after a mid-air collision with an Embraer Legacy 600 business jet; The 2006 Yogyakarta earthquake kills over 5,700 people; The IAU votes on the definition of "planet", which demotes Pluto and other Kuiper belt objects and redefines them as "dwarf planets"., 300x300px, thumb rect 0 0 200 200 2006 Winter Olympics rect 200 0 400 200 Twitter rect 400 0 600 200 Nintendo Wii rect 0 200 300 400 IAU definition of planet rect 300 200 600 400 2006 Montenegrin independence referendum rect 0 400 200 600 2006 Yogyakarta earthquake rect 200 400 400 600 Gol Transportes Aéreos Flight 1907 rect 400 400 600 600 2006 FIFA World Cup 2006 was ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
