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Jonathan Baell
Jonathan Baell (né Ball) is trained as an Australian medicinal chemist and is currently executive director, early leads chemistry at Lyterian Therapeutics in San Francisco. Prior to this, he was a research professor in medicinal chemistry at the Monash Institute of Pharmaceutical Sciences (MIPS), the director of the Australian Translational Medicinal Chemistry Facility and a Chief Investigator at the ARC Centre for Fragment-Based Design. He was President of the International Chemical Biology Society 2018-2021 and is currently chair of the board. His research focuses on the early stages of drug discovery, including high-throughput screening (HTS) library design, hit-to-lead and lead optimization for the treatment of a variety of diseases, such as malaria and neglected diseases. Early life and education Baell was born in Tanzania, East Africa in 1965. He migrated with his family to Tasmania, Australia in 1977. Baell completed a Bachelor of Science with Honours from the Univer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Professor
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital letter nearly always refers to a full professor. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ammi Visnaga
''Visnaga daucoides'' is a species of flowering plant in the carrot family known by many common names, including toothpick-plant, toothpickweed, bisnaga, khella, or sometimes bishop's weed. It is native to Europe, Asia, and North Africa, but it can be found throughout the world as an introduced species. Description This is an erect annual plant growing from a taproot to a maximum height near . The leaves are up to long and generally oval to triangular in shape but dissected into many small linear to lance-shaped segments. The inflorescence is a compound umbel of white flowers similar to those of other Apiaceae species. The fruit is a compressed oval-shaped body less than 3 millimeters long. This species is a source of khellin, a diuretic extract. Like its close relative ''Ammi majus'', ''Visnaga daucoides'' is commonly seen in gardens where it is grown from seed annually. Some authorities regard ''Visnaga daucoides'' as a synonym of ''Ammi visnaga''; and it is still widely ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Espacenet
Espacenet (formerly stylized as ''esp@cenet'') is a free online service for searching patents and patent applications. Espacenet was developed by the European Patent Office (EPO) together with the member states of the European Patent Organisation. Most member states have an Espacenet service in their national language, and access to the EPO's worldwide database, most of which is in English. In 2022, the Espacenet worldwide service claimed to have records on more than 140 million patent publications. History By launching Espacenet in 1998, the EPO is said to have "revolutionized public access to international patent information, releasing patent data from its paper prisons and changing forever how patents are disseminated, organized, searched, and retrieved." In 2004, i.e. in the early years of Espacenet, Nancy Lambert considered that, although free, Espacenet, like the United States Patent and Trademark Office (USPTO) database of US patents, "still tend dto have primitive searc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
IUPAC
The International Union of Pure and Applied Chemistry (IUPAC ) is an international federation of National Adhering Organizations working for the advancement of the chemical sciences, especially by developing nomenclature and terminology. It is a member of the International Science Council (ISC). IUPAC is registered in Zürich, Switzerland, and the administrative office, known as the "IUPAC Secretariat", is in Research Triangle Park, North Carolina, United States. This administrative office is headed by IUPAC's executive director, currently Lynn Soby. IUPAC was established in 1919 as the successor of the International Congress of Applied Chemistry for the advancement of chemistry. Its members, the National Adhering Organizations, can be national chemistry societies, national academies of sciences, or other bodies representing chemists. There are fifty-four National Adhering Organizations and three Associate National Adhering Organizations. IUPAC's Inter-divisional Committee on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Current Medicinal Chemistry
''Current Medicinal Chemistry'' is a peer-reviewed medical journal published by Bentham Science Publishers. The editor-in-chief is Atta-ur-Rahman, FRS (Kings College University of Cambridge Cambridge, UK). The journal covers developments in medicinal chemistry and rational drug design and publishes original research reports and review papers. A related journal titled ''Current Medicinal Chemistry – Anti-Cancer Agents'' was launched in 2001, and retitled as ''Anti-Cancer Agents in Medicinal Chemistry'' from the start of 2006 with (print), (online). Abstracting and indexing ''Current Medicinal Chemistry'' is indexed in the following databases: * Chemical Abstracts Service/CASSI * EMBASE *EMBiology *MEDLINE *Science Citation Index Expanded *Scopus According to the ''Journal Citation Reports'', the journal has a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bentham Science Publishers
Bentham Science Publishers is a company that publishes scientific, technical, and medical journals and e-books. It publishes over 100 subscription-based academic journals and almost 40 open access journals. As of 2021, 40 Bentham Science journals have received JCR impact factors, and they are a member of the Committee on Publication Ethics. ''Bentham Open'', its open access division, has received criticism for questionable peer-review practices as well as invitation spam; it was listed as a "potential, possible, or probable predatory scholarly open access publisher" in Jeffrey Beall's list of predatory publishers, before the list went defunct. History Bentham was incorporated in 1994 by Atta-ur-Rahman and his friend Matthew Honan as a private business entity at the Sharjah Airport International Free Trade Zone in the United Arab Emirates. An investigative profile from ''Sujag'' notes the publisher to have operated out of Pakistan — for the first six years, from the premise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MDPI
MDPI (Multidisciplinary Digital Publishing Institute) is a publisher of open access scientific journals. Founded by Shu-Kun Lin as a chemical sample archive, it now publishes over 390 peer-reviewed, open access journals. MDPI is the largest open access publisher in the world and the fifth largest publisher overall in terms of journal paper output. The number of published papers has been growing significantly in the last decade with year over year growth of over 50% in 2017, 2018 and 2019. As of June 2022, MDPI publishes 393 academic journals, including 93 journals indexed within the Science Citation Index Expanded, and 8 journals indexed within the Social Sciences Citation Index, with a total of 98 journals ranked with an impact factor. MDPI journals are included in the Directory of Open Access Journals. MDPI is a member of the Open Access Scholarly Publishers Association, a participating publisher and supporter of the Initiative for Open Citations, and a member of the Committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Future Medicinal Chemistry
''Future Medicinal Chemistry'' is a peer-reviewed medical journal covering all aspects of medicinal chemistry, including drug discovery, pharmacology, in silico drug design, structural characterization techniques, ADME-Tox investigations, and science policy, economic and intellectual property issues. It was established in 2009 and is published by Future Science. The editors-in-chief are Iwao Ojima (The State University of New York at Stony Brook) and Jonathan Baell (Monash University). Abstracting and indexing The journal is abstracted and indexed by BIOSIS Previews, Chemical Abstracts, Chemistry Citation Index, Embase/Excerpta Medica, Index Medicus/MEDLINE/PubMed, Science Citation Index Expanded, and Scopus. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of arti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Pharmacology And Experimental Therapeutics
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University (also the founder of the American Society for Biochemistry and Molecular Biology), with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis. Publications The society publishes three research journals and a review journal: the ''Journal of Pharmacology and Experimental Therapeutics'', ''Drug Metabolism and Disposition'', ''Molecular Pharmacology'', and ''Pharmacological Reviews'' Starting in 2012 these publications are only offered online. The society copublishes a who ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drug Pipeline
A drug pipeline is the set of drug candidates that an individual pharmaceutical company or the entire pharmaceutical industry collectively has under discovery or development at any given point in time. The drug pipeline is also sometimes restricted to a particular drug class or extended to mean the process of discovering drugs (the research and development pipeline). The R&D pipeline involves various phases that can broadly be grouped in 4 stages: discovery, pre-clinical, clinical trials and marketing (or post-approval). Pharmaceutical companies usually have a number of compounds in their pipelines at any given time. The drug pipeline is an important indicator of the value and future prospects of a company. Usually the more compounds in the pipeline, and the more advanced stage that these are in the better. Other factors that are taken into account when assessing the value of a pipeline include the size of the target market of each drug, the market share Market share is the pe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pan-assay Interference Compounds
Pan-assay interference compounds (PAINS) are chemical compounds that often give false positive results in high-throughput screens. PAINS tend to react nonspecifically with numerous biological targets rather than specifically affecting one desired target. A number of disruptive functional groups are shared by many PAINS. While a number of filters have been proposed and are used in virtual screening and computer-aided drug design, the accuracy of filters with regard to compounds they flag and don't flag has been criticized. Common PAINS include toxoflavin, isothiazolones, hydroxyphenyl hydrazones, curcumin, phenol-sulfonamides, rhodanines, enones, quinones, and catechols. See also *Drug discovery In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or b ... References Further readi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
