Joe Z. Tsien
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Joe Z. Tsien
Joe Z. Tsien is a neuroscientist who pioneered Cre/lox-neurogenetics in the mid-1990s, a versatile toolbox for neuroscientists to study the complex relationships between genes, neural circuits, and behaviors. He is also known as the creator of the smart mouse Doogie in the late 1990s while being a faculty member at Princeton University.Tsien, Building a Brainer Mouse. Scientific American, April, p62-68, 2000. http://www.bio.utexas.edu/courses/kalthoff/bio346/PDF/Readings/11Tsien%282000%29brainier.pdf Recently, he developed the ''Theory of Connectivity'' in an effort to explain the origin of intelligence, or the basic design principle underlying brain computation and intelligence. The theory states that brain computation is organized by a power-of-two-based permutation logic in constructing cell assemblies - the basic building blocks of neural circuits. The theory has received initial validation from experiments. The discovery of this basic computational logic of the brain can have im ...
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Doogie Mice
In neuroscience, long-term potentiation (LTP) is a persistent strengthening of synapses based on recent patterns of activity. These are patterns of synaptic activity that produce a long-lasting increase in signal transmission between two neurons. The opposite of LTP is long-term depression, which produces a long-lasting decrease in synaptic strength. It is one of several phenomena underlying synaptic plasticity, the ability of chemical synapses to change their strength. As memories are thought to be encoded by modification of synaptic strength, LTP is widely considered one of the major cellular mechanisms that underlies learning and memory. LTP was discovered in the rabbit hippocampus by Terje Lømo in 1966 and has remained a popular subject of research since. Many modern LTP studies seek to better understand its basic biology, while others aim to draw a causal link between LTP and behavioral learning. Still, others try to develop methods, pharmacologic or otherwise, of enhanci ...
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Memory Improvement
Memory improvement is the act of enhancing one's memory. Memory deficits, age-related memory loss, and people's want to improve their own memory have led to research on how to best help people to improve their memory. Research has also worked to determine what factors influence memory and cognition. Many different techniques to improve memory have been found, including cognitive training, psychopharmacology, diet, stress management, and exercise. Each technique has the ability to influence memory in different ways. Memory function factors Neuroplasticity Neuroplasticity is the mechanism by which the brain encodes experience, learns new behaviours and relearns lost behaviour if the brain has been damaged.Kleim, JA., & Jones, TA. (2008)Principles of experience-dependent neural plasticity: implications for rehabilitation after brain damage Journal of Speech, Language, and Hearing Research, 51, S225-S239. Experience-dependent neuroplasticity suggests that the brain changes in resp ...
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East China Normal University Alumni
East or Orient is one of the four cardinal directions or points of the compass. It is the opposite direction from west and is the direction from which the Sun rises on the Earth. Etymology As in other languages, the word is formed from the fact that east is the direction where the Sun rises: ''east'' comes from Middle English ''est'', from Old English ''ēast'', which itself comes from the Proto-Germanic *''aus-to-'' or *''austra-'' "east, toward the sunrise", from Proto-Indo-European *aus- "to shine," or "dawn", cognate with Old High German ''*ōstar'' "to the east", Latin ''aurora'' 'dawn', and Greek ''ēōs'' 'dawn, east'. Examples of the same formation in other languages include Latin oriens 'east, sunrise' from orior 'to rise, to originate', Greek ανατολή anatolé 'east' from ἀνατέλλω 'to rise' and Hebrew מִזְרָח mizraḥ 'east' from זָרַח zaraḥ 'to rise, to shine'. ''Ēostre'', a Germanic goddess of dawn, might have been a personification ...
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American Neuroscientists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ...
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Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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Wuyue
Wuyue (; ), 907–978, was an independent coastal kingdom founded during the Five Dynasties and Ten Kingdoms period (907–960) of Chinese history. It was ruled by the Haiyan Qian clan (海盐钱氏), whose family name remains widespread in the kingdom's former territory. Founding Beginning in 887, the Qian family provided military leaders (or ''jiedushi'') to the Tang dynasty. Qian Liu was named Prince of Yue in 902, with the title of Prince of Wu added two years later. In 907, when the Tang dynasty fell and was replaced in the north by the Later Liang, military leaders in the south formed their own kingdoms. Qian Liu used his position to proclaim himself the King of Wuyue. This signaled the beginning of the Five Dynasties and Ten Kingdoms period which would last until the founding of the Song dynasty in 960. Origin of name The name Wuyue comes from the combination of Wu Kingdom and Yue Kingdom, two ancient kingdoms during the Spring and Autumn period from 770 to ...
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Qian Liu
Qian Liu (10 March 852Academia Sinica Chinese-Western Calendar Converter
''Spring and Autumn Annals of the Ten Kingdoms'' (:zh:十國春秋, 十國春秋)
vol. 77
- 6 May 932,''Zizhi Tongjian'', :zh:s:資治通鑑/卷277, vol. 277. courtesy name Jumei), known as Qian Poliu during his childhood, was a warlord of the late Tang dynasty who founded the Wuyue kingdom.Qian Liu's title was ''Wang'' (王) in Chinese, which could be translated as either "Prince" or "King" in English. The translation of "Prince" will be used here initially when he was created the ''Wang'' of Pengcheng, then of Nankang, then of Yue, then of Wu, ...
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Shang Dynasty
The Shang dynasty (), also known as the Yin dynasty (), was a Chinese royal dynasty founded by Tang of Shang (Cheng Tang) that ruled in the Yellow River valley in the second millennium BC, traditionally succeeding the Xia dynasty and followed by the Western Zhou dynasty. The classic account of the Shang comes from texts such as the '' Book of Documents'', '' Bamboo Annals'' and '' Records of the Grand Historian''. According to the traditional chronology based on calculations made approximately 2,000 years ago by Liu Xin, the Shang ruled from 1766 to 1122 BC, but according to the chronology based upon the "current text" of ''Bamboo Annals'', they ruled from 1556 to 1046 BC. Comparing the same text with dates of five-planet conjunctions, David Pankenier, supported by David Nivison, proposed dates of the establishment of the dynasty to 1554 BC. The Xia–Shang–Zhou Chronology Project dated the establishment to c. 1600 BC based on the carbon-14 dates of th ...
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Zhuanxu
Zhuanxu (Chinese:  trad. , simp. , pinyin ''Zhuānxū''), also known as Gaoyang ( t , s , p ''Gāoyáng''), was a mythological emperor of ancient China. In the traditional account recorded by Sima Qian, Zhuanxu was a grandson of the Yellow Emperor who led the Shi Clan in an eastward migration to present-day Shandong, where intermarriages with the Dongyi clan enlarged and augmented their tribal influences. At age of twenty, he became their sovereign, going on to rule for seventy-eight years until his death. Family Zhuanxu was the grandson of the Yellow Emperor and his wife Leizu by way of his father Changyi (昌意). His mother was named Changpu (昌僕), according to Sima Qian, and Niuqu (女樞) according to the ''Bamboo Annals''. Zhuanxu was claimed as an ancestor by many of the dynasties of Chinese history, including the Mi of Chu and Yue, the Yíng of Qin, and the Cao of Wei. Reign Zhuanxu is held by many sources to be one of ...
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Qian Surname
Qian (; Shanghainese: ), also spelt Chin, Chien, Tsien, or Zee in Wu Chinese, is a common Chinese family name. The name literally means "money". Qian is listed at the second place in the Song Dynasty text ''Hundred Family Surnames'', in the line 趙錢孫李 ( Zhao, Qian, Sun, Li). As the royal surname of the kingdom of Wuyue, Qian was regarded as second only to Zhao, the imperial surname of the Song. As of 2008, Qian is the 96th most common surname in China, shared by 2.2 million people, with the province with the most people sharing the name being Jiangsu, an area formerly within the Wuyue kingdom. Origins According to the Song dynasty book, '' Tongzhi'', the Qian surname is descended from Zhuanxu, one of the legendary Five Emperors, via Pengzu, the founder of the Peng kingdom in modern-day Jiangsu during the Shang dynasty. A Zhou dynasty official, Fu, was a descendant of Pengzu and served in the royal Treasury, the ''Qianfu'' ("Money Office"). His descendants adopted the sur ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ...
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