Jörgen Lehmann
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Jörgen Lehmann
J̦rgen Erik Lehmann (15 January 1898 Р26 December 1989) was a Danish-Swedish physician and chemist best known for his discovery in the 1940s that para-amino salicylic acid (PAS) would make an excellent orally-available tuberculosis therapy. PAS was, together with streptomycin, the first efficacious anti-microbial therapy for tuberculosis and remained in clinical use for several decades. In 1941, Lehmann also developed the anti-coagulant dicumarol, which is used for the prevention of blood clots and in the treatment of deep venous thrombosis. Lehmann studied under Torsten Thunberg, professor of physiology in Lund, who discovered the dehydrogenases. Lehmann was appointed professor of physiology in Aarhus in 1937, and became head of the central laboratory at the Sahlgrenska University Hospital in Gothenburg 1938. After retiring in 1963, Lehmann continued his research at the Nobel Laureate Arvid Carlsson's institution at the University of Gothenburg. J̦rgen Lehmann was son o ...
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ...
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Dehydrogenase
A dehydrogenase is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. Like all catalysts, they catalyze reverse as well as forward reactions, and in some cases this has physiological significance: for example, alcohol dehydrogenase catalyzes the oxidation of ethanol to acetaldehyde in animals, but in yeast it catalyzes the production of ethanol from acetaldehyde. IUBMB Classification Oxidoreductases, enzymes that catalyze oxidation-reduction reactions, constitute Class EC 1 of the IUBMB classification of enzyme-catalyzed reactions. Any of these may be called dehydrogenases, especially those in which NAD+ is the electron acceptor (oxidant), but reductase is also used when the physiological emphasis on reduction of the substrate, and oxidase is used ''only'' when O2 is the electron acceptor. The systematic name of an oxidoreductase is "donor:acceptor oxidore ...
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Academic Staff Of The University Of Gothenburg
An academy (Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, dev ...
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University Of Gothenburg Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university in ...
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Swedish Chemists
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) Swedish Open is a tennis tournament. Swedish Open may also refer to: *Swedish Open (badminton) * Swedish Open (table tennis) *Swedish Open (squash) *Swedish Open (darts) The Swedish Open is a darts tournament established in 1969, held in Malmà ... {{disambig Language and nationality disambiguation pages ...
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1989 Deaths
File:1989 Events Collage.png, From left, clockwise: The Cypress Street Viaduct, Cypress structure collapses as a result of the 1989 Loma Prieta earthquake, killing motorists below; The proposal document for the World Wide Web is submitted; The Exxon Valdez oil tanker runs aground in Prince William Sound, Alaska, causing a large Exxon Valdez oil spill, oil spill; The Fall of the Berlin Wall begins the downfall of Communism in Eastern Europe, and heralds German reunification; The United States United States invasion of Panama, invades Panama to depose Manuel Noriega; The Singing Revolution led to the independence of the Baltic states of Estonia, Latvia, and Lithuania from the Soviet Union; The stands of Hillsborough Stadium in Sheffield, Yorkshire, where the Hillsborough disaster occurred; 1989 Tiananmen Square protests and massacre, Students demonstrate in Tiananmen Square, Beijing; many are killed by forces of the Chinese Communist Party., 300x300px, thumb rect 0 0 200 200 1989 Loma ...
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1898 Births
Events January–March * January 1 – New York City annexes land from surrounding counties, creating the City of Greater New York as the world's second largest. The city is geographically divided into five boroughs: Manhattan, Brooklyn, Queens, The Bronx and Staten Island. * January 13 – Novelist Émile Zola's open letter to the President of the French Republic on the Dreyfus affair, ''J'Accuse…!'', is published on the front page of the Paris daily newspaper ''L'Aurore'', accusing the government of wrongfully imprisoning Alfred Dreyfus and of antisemitism. * February 12 – The automobile belonging to Henry Lindfield of Brighton rolls out of control down a hill in Purley, London, England, and hits a tree; thus he becomes the world's first fatality from an automobile accident on a public highway. * February 15 – Spanish–American War: The USS ''Maine'' explodes and sinks in Havana Harbor, Cuba, for reasons never fully established, killing 266 ...
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