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John Quackenbush
John Quackenbush is an American computational biologist and genome scientist. He is a professor of biostatistics and computational biology and a professor of cancer biology at the Dana–Farber Cancer Institute (DFCI), as well as the director of its Center for Cancer Computational Biology (CCCB). Quackenbush also holds an appointment as a professor of computational biology and bioinformatics in the Department of Biostatistics at the Harvard School of Public Health. Education and early life A native of Mountain Top, Pennsylvania, Quackenbush attended Bishop Hoban High School in Wilkes Barre, graduating in 1979, after which he attended the California Institute of Technology, where he earned a bachelor's degree in physics. He went on to earn a doctorate in theoretical physics from the University of California, Los Angeles in 1990. Career and research After working two years as a postdoctoral fellow in physics, Quackenbush was awarded a Special Emphasis Research Career Award from t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kingston, Pennsylvania
Kingston is a borough in Luzerne County, Pennsylvania, United States. It is located on the western bank of the Susquehanna River opposite the city of Wilkes-Barre. Kingston was first settled in the early 1770s; it was incorporated as a borough in 1857. As of the 2020 census, the population was 13,349, making it the most populous borough in the county. History Early history In the early 1660s, King Charles II owed Admiral Sir William Penn a large sum of money. To settle this debt, he granted Penn’s son, William, a territory in North America, which later became known as Pennsylvania. However, Connecticut also claimed a portion of this land. Count Zinzendorf was one of the first people to take an interest in the Wyoming Valley. In 1742, he came to the region to convert the Native Americans to Christianity. At the time, the valley was inhabited by several Native American tribes (including the Susquehannock and the Delaware). His reports led a group of Connecticut settlers to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to pursue additional research, training, or teaching in order to have better skills to pursue a career in academia, research, or any other field. Postdocs often, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further formal qualificati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ProQuest
ProQuest LLC is an Ann Arbor, Michigan-based global information-content and technology company, founded in 1938 as University Microfilms by Eugene B. Power. ProQuest is known for its applications and information services for libraries, providing access to dissertations, theses, ebooks, newspapers, periodicals, historical collections, governmental archives, cultural archives,"Jisc and ProQuest Enable Access to Essential Digital Content" retrieved May 21, 2014 and other aggregated databases. This content was estimated to be around 125 billion digital pages, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theoretical Physics
Theoretical physics is a branch of physics that employs mathematical models and abstractions of physical objects and systems to rationalize, explain and predict natural phenomena. This is in contrast to experimental physics, which uses experimental tools to probe these phenomena. The advancement of science generally depends on the interplay between experimental studies and theory. In some cases, theoretical physics adheres to standards of mathematical rigour while giving little weight to experiments and observations.There is some debate as to whether or not theoretical physics uses mathematics to build intuition and illustrativeness to extract physical insight (especially when normal experience fails), rather than as a tool in formalizing theories. This links to the question of it using mathematics in a less formally rigorous, and more intuitive or heuristic way than, say, mathematical physics. For example, while developing special relativity, Albert Einstein was concerned wit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilkes Barre
Wilkes-Barre ( or ) is a city in the U.S. state of Pennsylvania and the county seat of Luzerne County. Located at the center of the Wyoming Valley in Northeastern Pennsylvania, it had a population of 44,328 in the 2020 census. It is the second-largest city, after Scranton, in the Scranton–Wilkes-Barre–Hazleton, PA Metropolitan Statistical Area, which had a population of 563,631 as of the 2010 census and is the fourth-largest metropolitan area in Pennsylvania after the Delaware Valley, Greater Pittsburgh, and the Lehigh Valley with an urban population of 401,884. Scranton/Wilkes-Barre is the cultural and economic center of a region called Northeastern Pennsylvania, which is home to over 1.3 million residents. Wilkes-Barre and the surrounding Wyoming Valley are framed by the Pocono Mountains to the east, the Endless Mountains to the north and west, and the Lehigh Valley to the south. The Susquehanna River flows through the center of the valley and defines the northwestern ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bishop Hoban High School
Bishop Hoban High School was a Roman Catholic high school of the Diocese of Scranton, located in Wilkes-Barre, Pennsylvania. The school was founded in 1971, and the new building opened in 1972 after repairs due to the catastrophic flooding caused by Tropical Storm Agnes. The school was named after Most Rev. Michael J. Hoban, second Bishop of Scranton (1899–1926). Bishop Hoban's colors were green and gold, and the school's nickname was the Argents. The last graduating class of Bishop Hoban graduated on May 24, 2007. Bishop Hoban High School closed on July 1, 2007, and became part of a consolidation of the four diocesan high schools of Luzerne County (see below). The building now houses Holy Redeemer High School. The largest high school of the Diocese of Scranton, Bishop Hoban had an annual enrollment of around 650 (grades 9 through 12) with nearly 60 faculty and administrators. The school was accredited by the Middle States Association of Colleges and Schools The Middle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mountain Top, Pennsylvania
Mountain Top is an unincorporated area and census-designated place (CDP) in Luzerne County, Pennsylvania, United States. As of the 2010 census, the CDP population was 10,982. The Mountain Top CDP is located along Pennsylvania Route 309 (south of Wilkes-Barre) in Fairview, Wright,Rice townships and Dorrance Township. Name The area's name is properly spelled "Mountain Top". The United States Postal Service uses the spelling "Mountain Top" for ZIP Code 18707, and the Pennsylvania Department of Transportation spells it "Mountain Top" on a Pennsylvania driver's license. However, some businesses in Mountain Top spell their community as a single word, "Mountaintop". Geography Mountain Top, once named "Penobscot", is located in central Luzerne County at (41.1353022, -75.9044749). The CDP extends north to Solomon Gap, which separates Penobscot Knob to the west from Haystack Mountain to the east. To the south, the CDP includes the settlements of Fairview Heights, Wech Corners, Rita, A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard School Of Public Health
The Harvard T.H. Chan School of Public Health is the public health school of Harvard University, located in the Longwood Medical Area of Boston, Massachusetts. The school grew out of the Harvard-MIT School for Health Officers, the nation's first graduate training program in population health, which was founded in 1913 and then became the Harvard School of Public Health in 1922. Harvard's T.H. Chan School of Public Health is currently ranked as the best school for public health in the world by both the ''Academic Ranking of World Universities'' and EduRank. It is also ranked as the second (tie) best public health school in the nation by '' U.S. News & World Report''. History Harvard's T.H. School of Public Health traces its origins to the Harvard-MIT School for Health Officers, which was founded in 1913. Harvard calls it "the nation's first graduate training program in public health." In 1922, the School for Health Officers became the Harvard School of Public Health. In 1946, it ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biostatistics
Biostatistics (also known as biometry) are the development and application of statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results. History Biostatistics and genetics Biostatistical modeling forms an important part of numerous modern biological theories. Genetics studies, since its beginning, used statistical concepts to understand observed experimental results. Some genetics scientists even contributed with statistical advances with the development of methods and tools. Gregor Mendel started the genetics studies investigating genetics segregation patterns in families of peas and used statistics to explain the collected data. In the early 1900s, after the rediscovery of Mendel's Mendelian inheritance work, there were gaps in understanding between genetics and evolutionary Darwinism. Francis Galton tried to expand Mendel's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biology
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary information encoded in genes, which can be transmitted to future generations. Another major theme is evolution, which explains the unity and diversity of life. Energy processing is also important to life as it allows organisms to move, grow, and reproduce. Finally, all organisms are able to regulate their own internal environments. Biologists are able to study life at multiple levels of organization, from the molecular biology of a cell to the anatomy and physiology of plants and animals, and evolution of populations.Based on definition from: Hence, there are multiple subdisciplines within biology, each defined by the nature of their research questions and the tools that they use. Like other scientists, biologists use the sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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