John James Pringle
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John James Pringle
John James Pringle (1855 – 18 December 1922) was a Scottish dermatologist. Biography Pringle was born in Borgue, Kirkcudbrightshire and educated at Merchiston Castle School. He graduated in medicine from the University of Edinburgh in 1876. He then travelled abroad, studying in Dublin, Vienna, Paris and Berlin. He studying dermatology in Vienna under Ferdinand von Hebra and Moriz Kaposi, and in Paris under Jean Baptiste Emile Vidal and Jean Alfred Fournier. He settled in London in 1882. From 1888 to 1920, he worked as a dermatologist at the Middlesex Hospital in London. He caught tuberculosis and spent six months of 1903 in a sanatorium. He never fully recovered and, whilst on a trip intended to improve his health, he died at Christchurch, New Zealand. He is related to Sir John Pringle. Adenoma sebaceum JJ Pringle is primarily remembered for the eponym: Pringle's Adenoma Sebaceum. Now known as facial angiofibroma, this papular facial rash, of distinctive butterfly distr ...
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John James Pringle
John James Pringle (1855 – 18 December 1922) was a Scottish dermatologist. Biography Pringle was born in Borgue, Kirkcudbrightshire and educated at Merchiston Castle School. He graduated in medicine from the University of Edinburgh in 1876. He then travelled abroad, studying in Dublin, Vienna, Paris and Berlin. He studying dermatology in Vienna under Ferdinand von Hebra and Moriz Kaposi, and in Paris under Jean Baptiste Emile Vidal and Jean Alfred Fournier. He settled in London in 1882. From 1888 to 1920, he worked as a dermatologist at the Middlesex Hospital in London. He caught tuberculosis and spent six months of 1903 in a sanatorium. He never fully recovered and, whilst on a trip intended to improve his health, he died at Christchurch, New Zealand. He is related to Sir John Pringle. Adenoma sebaceum JJ Pringle is primarily remembered for the eponym: Pringle's Adenoma Sebaceum. Now known as facial angiofibroma, this papular facial rash, of distinctive butterfly distr ...
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Sanatorium
A sanatorium (from Latin '' sānāre'' 'to heal, make healthy'), also sanitarium or sanitorium, are antiquated names for specialised hospitals, for the treatment of specific diseases, related ailments and convalescence. Sanatoriums are often located in a healthy climate, usually in the countryside. The idea of healing was an important reason for the historical wave of establishments of sanatoriums, especially at the end of the 19th- and early 20th centuries. One sought for instance the healing of consumptives, especially tuberculosis (before the discovery of antibiotics) or alcoholism, but also of more obscure addictions and longings, of hysteria, masturbation, fatigue and emotional exhaustion. Facility operators were often charitable associations such as the Order of St. John and the newly founded social welfare insurance companies. Sanatoriums should not be confused with the Russian sanatoriums from the time of the Soviet Union, which were a type of sanatorium resort r ...
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Timeline Of Tuberous Sclerosis
The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic disease that can cause benign tumours to grow on the brain or other vital organs such as the kidneys, heart, eyes, lungs, and skin. A combination of symptoms may include seizures, developmental delay, behavioural problems and skin abnormalities, as well as lung and kidney disease. TSC is caused by mutations on either of two genes, TSC1 and TSC2, which encode for the proteins hamartin and tuberin respectively. These proteins act as tumour growth suppressors and regulate cell proliferation and differentiation. Originally regarded as a rare pathological curiosity, it is now an important focus of research into tumour formation and suppression. The history of TSC research is commonly divided into four periods.Rott (2005), page 2 - Introduction. In the late 19th century, notable physicians working in European teaching hospitals first described the cortical and dermatologica ...
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Angiokeratoma
Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis. ''Angiokeratoma corporis diffusum'' refers to Fabry's disease, but this is usually considered a distinct condition. Signs and symptoms Presentation includes telangiectasia, acanthosis, and hyperkeratosis. Presentation can be solitary or systemic. Multiple angiokeratomas, especially on the trunk in young people, are typical for Fabry disease, genetic disorder connected with systemic complications. Complications In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal, bacterial and viral infections. Infections can include staphylococcus. If the lesion becomes painful, begins draining fluids or pus, or begins to smell, consult a physician. In these instance a doctor may recommend excision and grafting. Pathophysiology Histology Angiokeratomas characteristically have large dilated blood vess ...
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British Journal Of Dermatology
The ''British Journal of Dermatology'' is a monthly peer-reviewed medical journal that covers the field of dermatology. It is published by Wiley-Blackwell on behalf of the British Association of Dermatologists. The journal was established in 1888 and the editor-in-chief is John Ingram. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 9.3., ranked third within the dermatology subject category. It was edited from 1896 to 1904 by Sir James Galloway. References External links * {{Official, https://onlinelibrary.wiley.com/journal/13652133 British Association of Dermatologists Publications established in 1888 English-language journals Monthly journals Wiley-Blackwell academic journals Derm ...
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Heinrich Vogt (neurologist)
Heinrich Vogt (23 April 1875, in Regensburg – 24 September 1957, in Bad Pyrmont) was a German neurologist.The Founders of Child Neurology
edited by Stephen Ashwal He published papers on and , and was the author of a handbook on the treatment of nervous diseases. In 1901 he obtained his

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Tuberous Sclerosis
Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant genetic disease that causes non-cancerous tumours to grow in the brain and on other vital organs such as the kidneys, heart, liver, eyes, lungs and skin. A combination of symptoms may include seizures, intellectual disability, developmental delay, behavioral problems, skin abnormalities, lung disease, and kidney disease. TSC is caused by a mutation of either of two genes, ''TSC1'' and ''TSC2'', which code for the proteins hamartin and tuberin, respectively, with ''TSC2'' mutations accounting for the majority and tending to cause more severe symptoms. These proteins act as tumor growth suppressors, agents that regulate cell proliferation and differentiation. Prognosis is highly variable and depends on the symptoms, but life expectancy is normal for many. The prevalence of the disease is estimated to be 7 to 12 in 100,000. The disease is often abbreviated to tuberous sclerosis, which refers to the har ...
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Epilepsy
Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. Epileptic seizures can vary from brief and nearly undetectable periods to long periods of vigorous shaking due to abnormal electrical activity in the brain. These episodes can result in physical injuries, either directly such as broken bones or through causing accidents. In epilepsy, seizures tend to recur and may have no immediate underlying cause. Isolated seizures that are provoked by a specific cause such as poisoning are not deemed to represent epilepsy. People with epilepsy may be treated differently in various areas of the world and experience varying degrees of social stigma due to the alarming nature of their symptoms. The underlying mechanism of epileptic seizures is excessive and abnormal neuronal activity in the cortex of the brain which can be observed in the electroencephalogram (EEG) of an individual. The reason this occurs in most cases of epilepsy is u ...
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Sebaceous Glands
A sebaceous gland is a microscopic exocrine gland in the skin that opens into a hair follicle to secrete an oily or waxy matter, called sebum, which lubricates the hair and skin of mammals. In humans, sebaceous glands occur in the greatest number on the face and scalp, but also on all parts of the skin except the palms of the hands and soles of the feet. In the eyelids, meibomian glands, also called tarsal glands, are a type of sebaceous gland that secrete a special type of sebum into tears. Surrounding the female nipple, areolar glands are specialized sebaceous glands for lubricating the nipple. Fordyce spots are benign, visible, sebaceous glands found usually on the lips, gums and inner cheeks, and genitals. Structure Location Sebaceous glands are found throughout all areas of the skin, except the palms of the hands and soles of the feet. There are two types of sebaceous glands, those connected to hair follicles and those that exist independently. Sebaceous glands are found ...
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Adenoma
An adenoma is a benign tumor of epithelial tissue with glandular origin, glandular characteristics, or both. Adenomas can grow from many glandular organs, including the adrenal glands, pituitary gland, thyroid, prostate, and others. Some adenomas grow from epithelial tissue in nonglandular areas but express glandular tissue structure (as can happen in familial polyposis coli). Although adenomas are benign, they should be treated as pre-cancerous. Over time adenomas may transform to become malignant, at which point they are called adenocarcinomas. Most adenomas do not transform. However, even though benign, they have the potential to cause serious health complications by compressing other structures (mass effect) and by producing large amounts of hormones in an unregulated, non-feedback-dependent manner (causing paraneoplastic syndromes). Some adenomas are too small to be seen macroscopically but can still cause clinical symptoms. Histopathology Adenoma is a benign tumor of ...
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Félix Balzer
Félix Balzer (4 April 1849 – 15 March 1929) was a French physician, specialising in dermatology and pathology. Balzer gave an early description of pseudoxanthoma elasticum in 1884. He used the term "''xanthome elastique''" but subsequently it was found not to be a form of xanthomatosis. Balzer is also responsible for coining the term "''adénomes sébacés''" (adenoma sebaceum) to describe the papular facial rash of tuberous sclerosis. Again, this term proved to be incorrect since the papules were neither adenoma nor derived from sebaceous glands. Between 1880 and 1887, Balzer was a director of the histology laboratory in the Faculty of the hospital Saint Louis. He became a member of the ''Académie de Médecine'' in 1908. He was also president of ''la Société Française de Dermatologie''. Papers * * * * * See also * Timeline of tuberous sclerosis The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic d ...
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Eponym
An eponym is a person, a place, or a thing after whom or which someone or something is, or is believed to be, named. The adjectives which are derived from the word eponym include ''eponymous'' and ''eponymic''. Usage of the word The term ''eponym'' functions in multiple related ways, all based on an explicit relationship between two named things. A person, place, or thing named after a particular person share an eponymous relationship. In this way, Elizabeth I of England is the eponym of the Elizabethan era. When Henry Ford is referred to as "the ''eponymous'' founder of the Ford Motor Company", his surname "Ford" serves as the eponym. The term also refers to the title character of a fictional work (such as Rocky Balboa of the Rocky film series, ''Rocky'' film series), as well as to ''self-titled'' works named after their creators (such as the album The Doors (album), ''The Doors'' by the band the Doors). Walt Disney created the eponymous The Walt Disney Company, Walt Disney Com ...
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