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John J. M. Bergeron
John J. M. Bergeron, (born December 22, 1946) is a Canadian cell biologist and biochemist. He is an Emeritus Robert Reford Professor of Anatomy and Professor of Medicine at McGill University in Montreal, Quebec, Canada. He is a Rhodes Scholar (Class of 1966). He is best known for the discovery of calnexin, endosomal signalling and organellar proteomics. Education Bergeron was born in Belleville, Ontario and grew up in and around the Montreal area, QC. He received the Montreal Science Fair award at Université de Montréal in 1961 which allowed him to pursue his studies and receive a B.Sc. in honours biochemistry McGill University in 1966. He continued his graduate work as a Rhodes Scholar at Oxford University, graduating with a D.Phil in biochemistry in 1969. From 1969 to 1971, he continued his post-doctoral training at the Rockefeller University (Supervisor: Dr. G. Palade). He then became an MRC Scientist the National Institute for Medical Research at Mill Hill, Lond ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belleville, Ontario
Belleville is a city in Ontario, Canada situated on the eastern end of Lake Ontario, located at the mouth of the Moira River and on the Bay of Quinte. Belleville is between Ottawa and Toronto, along the Quebec City-Windsor Corridor. Its population as of the Canada 2016 Census, 2016 census was 50,716 (census agglomeration population 103,472). It is the seat of Hastings County, but politically Independent city, independent of it, and is the centre of the Bay of Quinte Region. History The city is situated on the traditional territory of the Wyandot people, Wendat, Anishinaabe, Anishnaabeg, and Haudenosaunee peoples. The historic Anishinaabe (Mississaugas) village, known as ''Asukhknosk'' in the 18th century, was part of land purchased by the Crown to use for the resettlement of United Empire Loyalists who were forced to leave the Thirteen Colonies in North America, after the United States achieved independence. The settlement was first called Singleton's Creek after an early sett ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McGill University
McGill University (french: link=no, Université McGill) is an English-language public research university located in Montreal, Quebec, Canada. Founded in 1821 by royal charter granted by King George IV,Frost, Stanley Brice. ''McGill University, Vol. I. For the Advancement of Learning, 1801–1895.'' McGill-Queen's University Press, 1980. the university bears the name of James McGill, a Scottish merchant whose bequest in 1813 formed the university's precursor, University of McGill College (or simply, McGill College); the name was officially changed to McGill University in 1885. McGill's main campus is on the slope of Mount Royal in downtown Montreal in the borough of Ville-Marie, with a second campus situated in Sainte-Anne-de-Bellevue, west of the main campus on Montreal Island. The university is one of two members of the Association of American Universities located outside the United States, alongside the University of Toronto, and is the only Canadian member of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Queen Elizabeth II Diamond Jubilee Medal
The Queen Elizabeth II Diamond Jubilee Medal (french: Médaille du jubilé de diamant de la reine Elizabeth II) or The Queen's Diamond Jubilee Medal was a commemorative medal created in 2012 to mark the 60th anniversary of Queen Elizabeth II's accession in 1952. There are four versions of the medal: one issued by the United Kingdom, another by Canada, the third for the Caribbean realms of Antigua and Barbuda, the Bahamas, Barbados, Grenada, Jamaica, Saint Kitts and Nevis, Saint Lucia, and Saint Vincent and the Grenadines, and the fourth issued by Papua New Guinea. The ribbons used with the Canadian and British versions of the medal are the same, while the ribbon of the Caribbean and the Papua New Guinean medal differ slightly. The different iterations of the medal were presented to tens of thousands of recipients throughout the Commonwealth realms in the jubilee year. Design Named by Order in Council as the ''Queen Elizabeth II's Diamond Jubilee Medal'', the Canadian medal was d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Canadian Institutes For Health Research
The Canadian Institutes of Health Research (CIHR; french: Instituts de recherche en santé du Canada; IRSC) is a federal agency responsible for funding health and medical research in Canada. Comprising 13 institutes, it is the successor to the Medical Research Council of Canada. CIHR supports more than 13,000 researchers and trainees through grants, fellowships, scholarships, and other funding, as part of the federal government's investment in health research. The peer review process is a vital part of CIHR. Review by panels of peers from the research community ensures that proposals approved for funding by CIHR meet internationally accepted standards of scientific excellence. Along with the Social Sciences and Humanities Research Council, and the Natural Sciences and Engineering Research Council, the CIHR forms the major source of federal government funding to post-secondary research and are collectively referred to as the "Tri-Council" or "Tri-Agency". History CIHR was crea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Proteome Organization
The Human Proteome Organization (HUPO) is an international consortium of national proteomics research associations, government researchers, academic institutions, and industry partners. The organization was launched in February 2001, and it promotes the development and awareness of proteomics research, advocates on behalf of proteomics researchers throughout the world, and facilitates scientific collaborations between members and initiatives. Ultimately, it is organized to gain a better and more complete understanding of the human proteome. Congress Since 2002, HUPO organizes one international congress each year, with past congresses held in Orlando in 2018, in Dublin in 2017, in Taiwan in 2016 and in Vancouver 2015. Awards HUPO awards multiple awards each year, among them the * Distinguished Service Award * Translational Proteomics Award * Science & Technology Award * Discovery in Proteomic Sciences Award * Distinguished Achievement Award in Proteomic Sciences See also * Human ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Folding
Protein folding is the physical process by which a protein chain is translated to its native three-dimensional structure, typically a "folded" conformation by which the protein becomes biologically functional. Via an expeditious and reproducible process, a polypeptide folds into its characteristic three-dimensional structure from a random coil. Each protein exists first as an unfolded polypeptide or random coil after being translated from a sequence of mRNA to a linear chain of amino acids. At this stage the polypeptide lacks any stable (long-lasting) three-dimensional structure (the left hand side of the first figure). As the polypeptide chain is being synthesized by a ribosome, the linear chain begins to fold into its three-dimensional structure. Folding of many proteins begins even during translation of the polypeptide chain. Amino acids interact with each other to produce a well-defined three-dimensional structure, the folded protein (the right hand side of the figure), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Endosome
Endosomes are a collection of intracellular sorting organelles in eukaryotic cells. They are parts of endocytic membrane transport pathway originating from the trans Golgi network. Molecules or ligands internalized from the plasma membrane can follow this pathway all the way to lysosomes for degradation or can be recycled back to the cell membrane in the endocytic cycle. Molecules are also transported to endosomes from the trans Golgi network and either continue to lysosomes or recycle back to the Golgi apparatus. Endosomes can be classified as early, sorting, or late depending on their stage post internalization. Endosomes represent a major sorting compartment of the endomembrane system in cells. Function Endosomes provide an environment for material to be sorted before it reaches the degradative lysosome. For example, low-density lipoprotein (LDL) is taken into the cell by binding to the LDL receptor at the cell surface. Upon reaching early endosomes, the LDL dissociates ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute For Medical Research
The National Institute for Medical Research (commonly abbreviated to NIMR), was a medical research institute based in Mill Hill, on the outskirts of north London, England. It was funded by the Medical Research Council (MRC); In 2016, the NIMR became part of the new Francis Crick Institute, which was constructed next to St Pancras railway station in the Camden area of central London. History Foundation The Medical Research Council, founded in 1913, was immediately charged with establishing a central research institute in London. Later that year, premises at Hampstead were acquired and the National Institute for Medical Research was founded. However, the outbreak of World War I soon afterwards delayed occupation of the building, although senior staff were appointed and began work. By 1920 the institute at Mount Vernon Hospital was fully operational and remained so for 30 years until the move to Mill Hill. The original institute, under the directorship of Sir Henry Dale, had ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockefeller University
The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classified among "R2: Doctoral Universities – High research activity." Rockefeller is the oldest biomedical research institute in the United States. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Sciences, 17 members of the National Academy of Medicine, seven Lasker Award recipients, and five Nobel laureates. As of March 2022, a total of 26 Nobel laureates have been affiliated with Rockefeller University. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Université De Montréal
The Université de Montréal (UdeM; ; translates to University of Montreal) is a French-language public research university in Montreal, Quebec, Canada. The university's main campus is located in the Côte-des-Neiges neighborhood of Côte-des-Neiges–Notre-Dame-de-Grâce on Mount Royal near the Outremont Summit (also called Mount Murray), in the borough of Outremont. The institution comprises thirteen faculties, more than sixty departments and two affiliated schools: the Polytechnique Montréal (School of Engineering; formerly the École polytechnique de Montréal) and HEC Montréal (School of Business). It offers more than 650 undergraduate programmes and graduate programmes, including 71 doctoral programmes. The university was founded as a satellite campus of the Université Laval in 1878. It became an independent institution after it was issued a papal charter in 1919 and a provincial charter in 1920. Université de Montréal moved from Montreal's Quartier Latin to its pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Proteomics
Proteomics is the large-scale study of proteins. Proteins are vital parts of living organisms, with many functions such as the formation of structural fibers of muscle tissue, enzymatic digestion of food, or synthesis and replication of DNA. In addition, other kinds of proteins include antibodies that protect an organism from infection, and hormones that send important signals throughout the body. The proteome is the entire set of proteins produced or modified by an organism or system. Proteomics enables the identification of ever-increasing numbers of proteins. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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