John Hardy (geneticist)
Sir John Anthony Hardy (born 9 November 1954) is a human geneticist and molecular biologist at the Reta Lila Weston Institute of Neurological Studies at University College London with research interests in neurological diseases. Education Hardy attended St Ambrose College in the late 1960s, where his interest in biochemistry was encouraged by his Biology teacher, Mrs Cox. He received his Bachelor of Science degree from the University of Leeds in 1976Neuroscience NIH and his PhD from in 1981 for research on dopamine
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St Mary's Hospital, London
St Mary's Hospital is an NHS hospital in Paddington, in the City of Westminster, London, founded in 1845. Since the UK's first academic health science centre was created in 2008, it has been operated by Imperial College Healthcare NHS Trust, which also operates Charing Cross Hospital, Hammersmith Hospital, Queen Charlotte's and Chelsea Hospital and the Western Eye Hospital. Until 1988 the hospital ran St Mary's Hospital Medical School, part of the federal University of London. In 1988 it merged with Imperial College London, and then with Charing Cross and Westminster Medical School in 1997 to form Imperial College School of Medicine. In 2007 Imperial College became an independent institution when it withdrew from the University of London. History Development of the hospital The original block of St Mary's Hospital in Norfolk Place was designed by Thomas Hopper in the classical style. It first opened its doors to patients in 1851, the last of the great voluntary hospit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brain Prize
The Brain Prize, formerly known as The Grete Lundbeck European Brain Research Prize, is an international scientific award honouring "one or more scientists who have distinguished themselves by an outstanding contribution to neuroscience and who are still active in research". Founded in 2011 by thLundbeck Foundation the prize is associated with a DKK 10 million award to the nominees, the world’s largest brain research prize. Nominees can be of any nationality. Prize winners are expected to interact with Danish brain researchers e.g. through lectures, master classes, seminars, exchange programmes for researchers or other activities agreed with and financially supported by the Lundbeck Foundation. History The Brain Prize was established by the Lundbeck Foundation in 2010 as a European prize and was awarded for the first time in 2011. Today the Prize is global. Selection committee As of 2019, the selection committee for the prize consisted of: *Richard G. Morris (chair) *Story Landi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Michel Goedert
Michel Goedert FRS, FMedSci is a Luxembourgish-British neuroscientist and former Head of Neurobiology, at the MRC Laboratory of Molecular Biology. Goedert was born and raised in Luxembourg. After finishing his medical studies at the University of Basel in 1986, he started working at the Medical Research Council Laboratory of Molecular Biology affiliated with the University of Cambridge. Goedert was awarded the Metlife Foundation Award for Medical Research in Alzheimer's Disease in 1996, the Potamkin Prize in 1998 and the ''European Grand Prix for Research'' by the Foundation for Research on Alzheimer's disease in 2014. In 2018 he was one of four recipients of the Grete Lundbeck European Brain Research Prize with the citation "For their groundbreaking research on the genetic and molecular basis of Alzheimer's disease, with far-reaching implications for the development of new therapeutic interventions as well as for the understanding of other neurodegenerative diseases of the b ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bart De Strooper
Bart De Strooper is a Belgian molecular biologist and professor at Vlaams Instituut voor Biotechnologie and KU Leuven ( Leuven, Belgium) and the UK Dementia Research Institute and University College London, UK. His research interests are in Alzheimer's and other neurodegenerative diseases. Research and career De Strooper obtained an MD at the KU Leuven in 1985 and a PhD in 1992. He did a Postdoc at the EMBL in Heidelberg Germany in 1994. He has been VIB Group leader since 1999, and was Scientific Director, from 2007 to 2016, of the '' VIB Center for the Biology of Disease'' at KU Leuven (now VIB-KU Leuven Center for Brain & Disease Research). In December 2016 he became the director of the UK Dementia Research Institute at University College London. The institute, which has funding of £250m, was announced in May 2016. His research interest are the secretases, proteases which cleave the amyloid precursor protein (APP), resulting in amyloid peptides. The amyloid peptide is ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Christian Haass
Christian Haass (born 19 December 1960 in Mannheim, Germany) is a German biochemist who specializes in metabolic biochemistry and neuroscience. Haass studied biology in Heidelberg from 1981 to 1985. From 1990 on he was a postdoctoral fellow in the laboratory of Dennis Selkoe at Harvard Medical School, where he worked from 1993 to 1995 as an assistant professor. Afterwards he returned to Germany as professor of molecular biology at the Central Institute of Mental Health, Mannheim. In 1999 he was offered a chair in the medical faculty at the Ludwig Maximilian University of Munich. The emphasis of his work is in the molecular biology and cell biology of Alzheimer's disease and Parkinson's disease. He received Hamdan Award for Medical Research Excellence - Cytokines in Pathogenesis & Therapy of Diseases from Hamdan Medical Award in 2006. Among other awards, he has won the Leibniz Prize and the Metlife Foundation Award for Medical Research in Alzheimer's Disease. References Sourc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Breakthrough Prize
The Breakthrough Prizes are a set of international awards bestowed in three categories by the Breakthrough Prize Board in recognition of scientific advances. The awards are part of several "Breakthrough" initiatives founded and funded by Yuri Milner and his wife Julia Milner, along with Breakthrough Initiatives and Breakthrough Junior Challenge. *Breakthrough Prize in Mathematics *Breakthrough Prize in Fundamental Physics *Breakthrough Prize in Life Sciences The Breakthrough Prizes were founded by Sergey Brin, Priscilla Chan and Mark Zuckerberg, Yuri and Julia Milner, and Anne Wojcicki. The Prizes have been sponsored by the personal foundations established by Sergey Brin, Priscilla Chan and Mark Zuckerberg, Ma Huateng, Jack Ma, Yuri and Julia Milner, and Anne Wojcicki. Committees of previous laureates choose the winners from candidates nominated in a process that is online and open to the public. Laureates receive $3 million each in prize money. They attend a televised award ce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jacksonville
Jacksonville is a city located on the Atlantic coast of northeast Florida, the most populous city proper in the state and is the List of United States cities by area, largest city by area in the contiguous United States as of 2020. It is the county seat, seat of Duval County, Florida, Duval County, with which the city government Jacksonville Consolidation, consolidated in 1968. Consolidation gave Jacksonville its great size and placed most of its metropolitan population within the city limits. As of 2020 United States census, 2020, Jacksonville's population is 949,611, making it the List of United States cities by population, 12th most populous city in the U.S., the most populous city in the Southeastern United States, Southeast, and the most populous city in the Southern United States, South outside of the state of Texas. With a population of 1,733,937, the Jacksonville metropolitan area ranks as Florida's fourth-largest metropolitan region. Jacksonville straddles the St. Johns ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tampa
Tampa () is a city on the Gulf Coast of the U.S. state of Florida. The city's borders include the north shore of Tampa Bay and the east shore of Old Tampa Bay. Tampa is the largest city in the Tampa Bay area and the seat of Hillsborough County. With a population of 384,959 according to the 2020 census, Tampa is the third-most populated city in Florida after Jacksonville and Miami and is the 52nd most populated city in the United States. Tampa functioned as a military center during the 19th century with the establishment of Fort Brooke. The cigar industry was also brought to the city by Vincente Martinez Ybor, after whom Ybor City is named. Tampa was formally reincorporated as a city in 1887, following the Civil War. Today, Tampa's economy is driven by tourism, health care, finance, insurance, technology, construction, and the maritime industry. The bay's port is the largest in the state, responsible for over $15 billion in economic impact. The city is part of the Tampa-St. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Umeå
Umeå ( , , , locally ; South Westrobothnian: ;). fi, Uumaja; sju, Ubmeje; sma, Upmeje; se, Ubmi) is a city in northeast Sweden. It is the seat of Umeå Municipality and the capital of Västerbotten County. Situated on the Ume River, Umeå is the largest locality in Norrland and the thirteenth largest in Sweden, with a wider municipal population of 130,224 inhabitants in 2020. When Umeå University was established in 1965, growth accelerated, and the amount of housing has doubled in 30 years from 1980 to 2010. , Umeå was gaining around 1000 inhabitants per year and the municipality plans for having 200 000 inhabitants by 2050. The projection of municipality size in 2050 has, however, been questioned as an overestimation in an independent study. Umeå is a university town and centre of education, technical and medical research in northern Sweden. The two universities located in the city, Umeå University and one of the 3 main branches of SLU, host around 40,000 enrolled s ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |