|
Joel Rosenbaum
Joel Rosenbaum (born October 4, 1933) is a professor of cell biology at Yale University. Rosenbaum received his bachelor's degree from Syracuse University in 1955, and later his M.Sc. Ed. from St. Lawrence University in 1957. He returned later to Syracuse for his master's degree in 1959 and Ph.D. in 1963. His lab at Yale studies cilia and flagella, small tail-like organelles, using the model species Chlamydomonas, a single-cell alga. The lab is best known for its discovery of intraflagellar transport, a vital molecular process now linked to many human diseases, in 1993. Rosenbaum has continued to pursue intraflagellar transport as his main research interest. Rosenbaum received the E.B. Wilson Medal from the ASCB in 2006, the highest award given in the field of cell biology. References External links"Joel Rosenbaum,"member profile from the American Society for Cell Biology The American Society for Cell Biology (ASCB) is a professional society that was founded in 1960. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massena, New York
Massena is a town in St. Lawrence County, New York, United States. Massena is along the county's northern border, just south of the St. Lawrence River and the Three Nations Crossing of the Canada–United States border. The population was 12,883 at the 2010 census. The town of Massena contains a village also named Massena. History Massena was one of the first towns settled in St. Lawrence county, but was not incorporated until 1802 when it was formed from the town of Lisbon. The town and its village are named after André Masséna, a general and Marshal to Napoleon during the Napoleonic Wars The Napoleonic Wars (1803–1815) were a series of major global conflicts pitting the French Empire and its allies, led by Napoleon I, against a fluctuating array of European states formed into various coalitions. It produced a period of Fren .... The town suffered natural disasters in the 1944 Cornwall–Massena earthquake, 1944 Cornwall-Massena earthquake and in the January 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Syracuse University
Syracuse University (informally 'Cuse or SU) is a Private university, private research university in Syracuse, New York. Established in 1870 with roots in the Methodist Episcopal Church, the university has been nonsectarian since 1920. Located in the city's University Hill, Syracuse, University Hill neighborhood, east and southeast of Downtown Syracuse, the large campus features an eclectic mix of architecture, ranging from nineteenth-century Romanesque Revival architecture, Romanesque Revival to contemporary buildings. Syracuse University is organized into 13 schools and colleges, with nationally recognized programs in Syracuse University School of Architecture, architecture, Maxwell School of Citizenship and Public Affairs, public administration, S.I. Newhouse School of Public Communications, journalism and communications, Martin J. Whitman School of Management, business administration, Syracuse University School of Information Studies, information studies, Syracuse Univers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Newcomb Cleveland Prize
The Newcomb Cleveland Prize of the American Association for the Advancement of Science (AAAS) is annually awarded to author(s) of outstanding scientific paper published in the Research Articles or Reports sections of ''Science''. Established in 1923, funded by Newcomb Cleveland who remained anonymous until his death in 1951, and for this period it was known as the AAAS Thousand Dollar Prize. "The prize was inspired by Mr. Cleveland's belief that it was the scientist who counted and who needed the encouragement an unexpected monetary award could give." The present rules were instituted in 1975, previously it had gone to the author(s) of noteworthy papers, representing an outstanding contribution to science, presented in a regular session, sectional or societal, during the AAAS Annual Meeting. It is now sponsored by the Fodor Family Trust and includes a prize of $25,000. Recipients List of winners Current rules Previous rules See also * AAAS Award for Science Diplomacy * AAA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cilia
The cilium, plural cilia (), is a membrane-bound organelle found on most types of eukaryotic cell, and certain microorganisms known as ciliates. Cilia are absent in bacteria and archaea. The cilium has the shape of a slender threadlike projection that extends from the surface of the much larger cell body. Eukaryotic flagella found on sperm cells and many protozoans have a similar structure to motile cilia that enables swimming through liquids; they are longer than cilia and have a different undulating motion. There are two major classes of cilia: ''motile'' and ''non-motile'' cilia, each with a subtype, giving four types in all. A cell will typically have one primary cilium or many motile cilia. The structure of the cilium core called the axoneme determines the cilium class. Most motile cilia have a central pair of single microtubules surrounded by nine pairs of double microtubules called a 9+2 axoneme. Most non-motile cilia have a 9+0 axoneme that lacks the central pair of mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flagella
A flagellum (; ) is a hairlike appendage that protrudes from certain plant and animal sperm cells, and from a wide range of microorganisms to provide motility. Many protists with flagella are termed as flagellates. A microorganism may have from one to many flagella. A gram-negative bacterium ''Helicobacter pylori'' for example uses its multiple flagella to propel itself through the mucus lining to reach the stomach epithelium, where it may cause a gastric ulcer to develop. In some bacteria the flagellum can also function as a sensory organelle, being sensitive to wetness outside the cell. Across the three domains of Bacteria, Archaea, and Eukaryota the flagellum has a different structure, protein composition, and mechanism of propulsion but shares the same function of providing motility. The Latin word means " whip" to describe its lash-like swimming motion. The flagellum in archaea is called the archaellum to note its difference from the bacterial flagellum. Eukaryoti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organelle
In cell biology, an organelle is a specialized subunit, usually within a cell, that has a specific function. The name ''organelle'' comes from the idea that these structures are parts of cells, as organs are to the body, hence ''organelle,'' the suffix ''-elle'' being a diminutive. Organelles are either separately enclosed within their own lipid bilayers (also called membrane-bound organelles) or are spatially distinct functional units without a surrounding lipid bilayer (non-membrane bound organelles). Although most organelles are functional units within cells, some function units that extend outside of cells are often termed organelles, such as cilia, the flagellum and archaellum, and the trichocyst. Organelles are identified by microscopy, and can also be purified by cell fractionation. There are many types of organelles, particularly in eukaryotic cells. They include structures that make up the endomembrane system (such as the nuclear envelope, endoplasmic reticulum, and G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlamydomonas
''Chlamydomonas'' is a genus of green algae consisting of about 150 speciesSmith, G.M. 1955 ''Cryptogamic Botany Volume 1. Algae and Fungi'' McGraw-Hill Book Company Inc of unicellular flagellates, found in stagnant water and on damp soil, in freshwater, seawater, and even in snow as "snow algae". ''Chlamydomonas'' is used as a model organism for molecular biology, especially studies of flagellar motility and chloroplast dynamics, biogenesis, and genetics. One of the many striking features of ''Chlamydomonas'' is that it contains ion channels (channelrhodopsins) that are directly activated by light. Some regulatory systems of ''Chlamydomonas'' are more complex than their homologs in Gymnosperms, with evolutionarily related regulatory proteins being larger and containing additional domains. Molecular phylogeny studies indicated that the traditional genus ''Chlamydomonas'' as defined using morphological data was polyphyletic within Volvocales. Many species were subsequently ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intraflagellar Transport
Intraflagellar transport (IFT) is a bidirectional motility along axoneme microtubules that is essential for the formation (ciliogenesis) and maintenance of most eukaryotic cilia and flagella. It is thought to be required to build all cilia that assemble within a membrane projection from the cell surface. ''Plasmodium falciparum'' cilia and the sperm flagella of Drosophila are examples of cilia that assemble in the cytoplasm and do not require IFT. The process of IFT involves movement of large protein complexes called IFT particles or trains from the cell body to the ciliary tip and followed by their return to the cell body. The outward or anterograde movement is powered by kinesin-2 while the inward or retrograde movement is powered by cytoplasmic dynein 2/1b. The IFT particles are composed of about 20 proteins organized in two subcomplexes called complex A and B. IFT was first reported in 1993 by graduate student Keith Kozminski while working in the lab of Dr. Joel Rosenbaum at Yal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Society For Cell Biology
The American Society for Cell Biology (ASCB) is a professional society that was founded in 1960.American Society for Cell Biology records - Historical Note , Albin O. Kuhn Library & Gallery, . Accessed February 28, 2011. Its mission statement says: History On 6 April 1959 the passed a resolution for the establishm ...[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
