Jean-Marie Lehn
Jean-Marie Lehn (born 30 September 1939) is a French chemist. He received the Nobel Prize in Chemistry together with Donald Cram and Charles Pedersen in 1987 for his synthesis of cryptands. Lehn was an early innovator in the field of supramolecular chemistry, i.e., the chemistry of host–guest molecular assemblies created by intermolecular interactions, and continues to innovate in this field. his group has published 790 peer-reviewed articles in chemistry literature. Biography Early years Lehn was born in Rosheim, Alsace, France to Pierre and Marie Lehn. He is of Alsatian German descent. His father was a baker, but because of his interest in music, he later became the city organist. Lehn also studied music, saying that it became his major interest after science. He has continued to play the organ throughout his professional career as a scientist. His high school studies in Obernai, from 1950 to 1957, included Latin, Greek, German, and English languages, French literatur ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rosheim
Rosheim (; gsw-FR, Rose) is a commune in the Bas-Rhin department in Grand Est in north-eastern France. It lies southwest of Strasbourg, on the eastern slopes of the Vosges mountains. It is a winemaking town on the tourist "Road of the Wines of Alsace" and the Route Romane d'Alsace ("Romanesque route of Alsace"). Geography Distance from Paris 450 km, Strasbourg 25 km, Obernai 7 km, Molsheim 7 km. History Rosheim was first mentioned in a document in 778 as Rodasheim. In 1262 it received its town charter, combined with the right to build a town wall. From the 14th to 17th centuries, Rosheim was an Imperial City of the Holy Roman Empire, and founded the Décapole confederation with nine other Alsatian Imperial Cities in 1354, the goal was to maintain their rights. Like the other Decapolitan cities, it was awarded to France by the Peace of Westphalia and finally lost its independence under the Treaties of Nijmegen and was annexed by France. Population Sight ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Host–guest Chemistry
In supramolecular chemistry, host–guest chemistry describes complexes that are composed of two or more molecules or ions that are held together in unique structural relationships by forces other than those of full covalent bonds. Host–guest chemistry encompasses the idea of molecular recognition and interactions through non-covalent bonding. Non-covalent bonding is critical in maintaining the 3D structure of large molecules, such as proteins and is involved in many biological processes in which large molecules bind specifically but transiently to one another. Although non-covalent interactions could be roughly divided into those with more electrostatic or dispersive contributions, there are few commonly mentioned types of non-covalent interactions: ionic bonding, hydrogen bonding, van der Waals forces and hydrophobic interactions. Overview Host–guest chemistry is a branch of supramolecular chemistry in which a host molecule forms a chemical compound with a guest molecul ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vitamin B12
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, in both fatty acid and amino acid metabolism. It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow. Plants do not need cobalamin and carry out the reactions with enzymes that are not dependent on it. Vitamin B12 is the most chemically complex of all vitamins, and for humans, the only vitamin that must be sourced from animal-derived foods or from supplements. Only some archaea and bacteria can synthesize vitamin B12. Most people in developed countries get enough B12 from the consumption of meat or foods with animal sources. Foods containing vitamin B12 include meat, clams, liver, fish, poultry, eggs, and dairy products. Many breakfast cereals are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harvard University
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Robert Burns Woodward
Robert Burns Woodward (April 10, 1917 – July 8, 1979) was an American organic chemist. He is considered by many to be the most preeminent synthetic organic chemist of the twentieth century, having made many key contributions to the subject, especially in the synthesis of complex natural products and the determination of their molecular structure. He also worked closely with Roald Hoffmann on theoretical studies of chemical reactions. He was awarded the Nobel Prize in Chemistry in 1965. Early life and education Woodward was born in Boston, Massachusetts, on April 10, 1917. He was the son of Margaret Burns (an immigrant from Scotland who claimed to be a descendant of the poet, Robert Burns) and her husband, Arthur Chester Woodward, himself the son of Roxbury apothecary, Harlow Elliot Woodward. His father was one of the many victims of the 1918 influenza pandemic of 1918. From a very early age, Woodward was attracted to and engaged in private study of chemistry while he att ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Natural Sciences
Natural science is one of the branches of science concerned with the description, understanding and prediction of natural phenomena, based on empirical evidence from observation and experimentation. Mechanisms such as peer review and repeatability of findings are used to try to ensure the validity of scientific advances. Natural science can be divided into two main branches: life science and physical science. Life science is alternatively known as biology, and physical science is subdivided into branches: physics, chemistry, earth science, and astronomy. These branches of natural science may be further divided into more specialized branches (also known as fields). As empirical sciences, natural sciences use tools from the formal sciences, such as mathematics and logic, converting information about nature into measurements which can be explained as clear statements of the " laws of nature". Modern natural science succeeded more classical approaches to natural philosophy, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Philosophy
Philosophy (from , ) is the systematized study of general and fundamental questions, such as those about existence, reason, knowledge, values, mind, and language. Such questions are often posed as problems to be studied or resolved. Some sources claim the term was coined by Pythagoras ( BCE), although this theory is disputed by some. Philosophical methods include questioning, critical discussion, rational argument, and systematic presentation. in . Historically, ''philosophy'' encompassed all bodies of knowledge and a practitioner was known as a ''philosopher''."The English word "philosophy" is first attested to , meaning "knowledge, body of knowledge." "natural philosophy," which began as a discipline in ancient India and Ancient Greece, encompasses astronomy, medicine, and physics. For example, Newton's 1687 ''Mathematical Principles of Natural Philosophy'' later became classified as a book of physics. In the 19th century, the growth of modern research universiti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chemistry
Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a Chemical reaction, reaction with other Chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the properties ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Obernai
Obernai ( Alsatian: ''Owernah''; german: Oberehnheim) commune in the Bas-Rhin department in Alsace in north-eastern France. It lies on the eastern slopes of the Vosges mountains. Obernai is a rapidly growing city, its number of inhabitants having gone up from 6,304 in 1968 to 11,279 in 2017. History A neolithic necropole has been uncovered dating between 5,000 and 4,600 BC; 27 individuals were buried there in wooden coffins. This appears to be a continuation of groups from the Linear Pottery culture who were located also on the eastern side of the Rhine. The Obernai region, which was the property of the dukes of Alsace in the 7th century, is the birthplace of St. Odile, daughter of the Duke, who would become the Patron Saint of Alsace. The Obernai name first appears in 1240, when the village acquires the status of town under the tutelage of the Hohenstaufen family. The town then prospered. It became a member of the Décapole in 1354, an alliance of ten towns of the Holy Roman ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alsatians (people)
This is an incomplete list of well-known Alsatians and Lorrainians (people from the region of Alsace and the region of Lorraine). Alsatian culture is characterized by a blend of German and French influences. Alsatians *Jakob Ammann (1644–between 1712 and 1730), anabaptist preacher and namesake of Amish movement *Frédéric Auguste Bartholdi (1834–1904), sculptor, designer of the Statue of Liberty *Hippolyte Bernheim (1840–1919), neurologist *René Beeh (1886−1922), artist *Marc Bloch (1886–1944), historian *Jean Arp (1886–1966), artist *Hans Bethe (1906–2005), nuclear physicist, 1967 Nobel Prize in Physics laureate *Mehdi Baala (born 1978) *Karl Brandt * Sébastien Brant *Martin Bucer *Wolfgang Capito * Johann Stephan Decker (1784–1844), painter *Gustave Doré, artist, engraver, illustrator and sculptor *Alfred Dreyfus, military officer *Christine Ferber (born 1960), pastry chef and chocolatier *Charles de Foucauld *Charles Friedel *Charles Frédéric Gerhardt * ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alsace
Alsace (, ; ; Low Alemannic German/ gsw-FR, Elsàss ; german: Elsass ; la, Alsatia) is a cultural region and a territorial collectivity in eastern France, on the west bank of the upper Rhine next to Germany and Switzerland. In 2020, it had a population of 1,898,533. Alsatian culture is characterized by a blend of Germanic and French influences. Until 1871, Alsace included the area now known as the Territoire de Belfort, which formed its southernmost part. From 1982 to 2016, Alsace was the smallest administrative ''région'' in metropolitan France, consisting of the Bas-Rhin and Haut-Rhin departments. Territorial reform passed by the French Parliament in 2014 resulted in the merger of the Alsace administrative region with Champagne-Ardenne and Lorraine to form Grand Est. On 1 January 2021, the departments of Bas-Rhin and Haut-Rhin merged into the new European Collectivity of Alsace but remained part of the region Grand Est. Alsatian is an Alemannic dialect closely related ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |