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Janeway Lesion
Janeway lesions are rare, non- tender, small erythematous or haemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes. Definition Janeway lesions are painless, frequently haemorrhagic lesions seen most commonly on the palms and soles, particularly on the base of the thumb and little finger, and seen in infective endocarditis. Differential Osler's nodes and Janeway lesions are similar and point to the same diagnostic conclusion. The most significant difference between the two is that Osler's nodes present with tenderness, while Janeway lesions do not. Osler's nodes are thought to be due to immunologic phenomenon where deposition of immune complexes provoke inflammatory response, leading to swelling, redness and pain. On the contrary, Janeway lesions are thought to be due to embolic phenomenon in cutaneous blood vessels of palms and soles w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiology
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat adult heart disease. Surgical aspects are not included in cardiology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Necrosis
Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated digestion of cell components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal. Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated and result in the loss of cell membrane integrity and an uncontrolled release of products of cell death into the extracellular space. This initiates in the surrounding tissue an inflammatory response, which attracts leukocytes and nearby phagocytes which eliminate the dead cells by phagocytosis. However, microbial damaging substances released by leukocytes would crea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ILDS
The International League of Dermatological Societies (ILDS) is a non-governmental organization that works closely with the World Health Organization. It was founded in 1935, but because of World War II no congresses were held until 1952. It is governed by the International Committee of Dermatology. The ILDS is the parent organization of the International Foundation for Dermatology, founded in 1987. After the publication of ICD-10, the ILDS produced a series of compatible extensions for use in dermatology Dermatology is the branch of medicine dealing with the skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A dermatologist is a specialist medical .... References External links Official site HistoryInternational Foundation for DermatologyApplication to Dermatology of International Classification of Disease (ICD-11) Organizations established in 1935 Dermatology organi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roth's Spot
Roth's spots, also known as Litten spots or the Litten sign, are non-specific red spots with white or pale centres, seen on the retina and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV. Red and white retinal spots were first observed in 1872 by Swiss physician Moritz Roth, and named "Roth spots" six years later by Moritz Litten. They are typically observed via fundoscopy (using an ophthalmoscope to view inside the eye) or slit lamp exam. The original retinal spots identified in 1872 were attributed to nerve-fibres that had burst. Present-day analysis shows that they can be composed of coagulated fibrin including platelets, focal ischaemia, inflammatory infiltrate, infectious organisms, or neoplastic cells. Cause Roth's spots occur in conditions that predispose to endothelial damage of retinal capillaries, that is when there is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Cardiology
''Clinical Cardiology'' is a monthly peer-reviewed medical journal covering cardiology that was established in 1978. It is published by John Wiley & Sons and the editor-in-chief is A. John Camm (St George's, University of London). It is an official journal of the American Society for Preventive Cardiology. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 2.882. References External links * Publications established in 1978 Cardiology journals Monthly journals English-language journals Wiley (publisher) academic journals {{Cardiology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emanuel Libman
Emanuel Libman (August 22, 1872 – June 28, 1946) was a Jewish-American physician from New York City. Life Libman was born on August 22, 1872, in New York City, New York City, New York, the son of Fajbush Libman and Hulda Spivak. His father was a picture frame dealer who owned a small store on the Lower East Side. Libman graduated from the City College of New York, College of the City of New York with an A.B. in 1891 and from the Columbia University Vagelos College of Physicians and Surgeons, Columbia University College of Physicians and Surgeons with an M.D. in 1894. He then worked as a home physician at Mount Sinai Hospital (Manhattan), Mount Sinai Hospital from 1894 to 1896. He did post-graduate work in Berlin, Vienna, Graz, Munich, and Prague from 1896 to 1897, returned to Berlin for further studies in 1903 and 1909, and studied at Johns Hopkins School of Medicine in 1906. He was influenced by Francis Delafield while attending Columbia and by Edward Gamaliel Janeway, Edward G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Osler
Sir William Osler, 1st Baronet, (; July 12, 1849 – December 29, 1919) was a Canadian physician and one of the "Big Four" founding professors of Johns Hopkins Hospital. Osler created the first Residency (medicine), residency program for specialty training of physicians, and he was the first to bring medical students out of the lecture hall for bedside clinical training. He has frequently been described as the ''Father of Modern Medicine'' and one of the "greatest diagnosticians ever to wield a stethoscope". Osler was a person of many interests, who in addition to being a physician, was a bibliophile, historian, author, and renowned practical joker. Outside of medicine, he was passionate about medical libraries and medical history and among his achievements were the founding of the History of Medicine Society (formally "section"), at the Royal Society of Medicine, London. In the field of librarianship he was instrumental in founding the Medical Library Association of Great Brit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edward Gamaliel Janeway
Edward Gamaliel Janeway (August 31, 1841 – February 10, 1911) was an American physician who served as Health Commissioner of New York, and as president of the New York Medical Journal Association in the late nineteenth century. He was considered "one of America's premier internists in the late nineteenth and early twentieth centuries". Biography Edward Janeway was born near New Brunswick, New Jersey, August 31, 1841. He graduated from Rutgers College in 1860, receiving the degree of B.A. and M.A. from that institution. In 1864 he was graduated from the College of Physicians and Surgeons in New York, receiving the degree of M.D. While in the medical school in the years 1862 and 1863, he was made acting medical cadet in the United States Army hospitals at Newark, New Jersey. After graduation he worked at the Blackwell Island Smallpox Hospital before starting at Bellevue Hospital. In 1872, he became professor of pathology and practical anatomy in Bellevue Hospital Medical Colleg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Typhoid Fever
Typhoid fever, also known as typhoid, is a disease caused by '' Salmonella'' serotype Typhi bacteria. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several days. This is commonly accompanied by weakness, abdominal pain, constipation, headaches, and mild vomiting. Some people develop a skin rash with rose colored spots. In severe cases, people may experience confusion. Without treatment, symptoms may last weeks or months. Diarrhea may be severe, but is uncommon. Other people may carry the bacterium without being affected, but they are still able to spread the disease. Typhoid fever is a type of enteric fever, along with paratyphoid fever. ''S. enterica'' Typhi is believed to infect and replicate only within humans. Typhoid is caused by the bacterium ''Salmonella enterica'' subsp. ''enterica'' serovar Typhi growing in the intestines, peyers patches, mesenteric lymph nodes, spleen, liver ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haemolytic Anaemia
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). This most commonly occurs within the spleen, but also can occur in the reticuloendothelial system or mechanically (prosthetic valve damage). Hemolytic anemia accounts for 5% of all existing anemias. It has numerous possible consequences, ranging from general symptoms to life-threatening systemic effects. The general classification of hemolytic anemia is either intrinsic or extrinsic. Treatment depends on the type and cause of the hemolytic anemia. Symptoms of hemolytic anemia are similar to other forms of anemia (Fatigue (physical), fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones and pulmonary hypertension. Signs and symptoms Sym ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gonococcemia
Gonococcemia (also known as "Disseminated gonococcal infection") is a rare complication of mucosal ''Neisseria gonorrhoeae'' infection, or Gonorrhea, that occurs when the bacteria invade the bloodstream. It is characterized by fever, tender hemorrhagic pustules on the extremities or the trunk, migratory polyarthritis, and tenosynovitis. It also rarely leads to endocarditis and meningitis. This condition occurs in 0.5-3% of individuals with gonorrhea, and it usually presents 2–3 weeks after acquiring the infection. Risk factors include female sex, sexual promiscuity, and infection with resistant strains of ''Neisseria gonorrhoeae''. This condition is treated with cephalosporin and fluoroquinolone antibiotics. Epidemiology ''Neisseria gonorrhoeae'' is a Gram-negative bacteria, gram negative diplococcus (also referred to as "Gonococcus") and a pathogenic bacteria. In 2019, there were 616,392 reported cases of gonorrhea in the United States, with an overall increased rate 5.7% fr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
