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James C. Paulson
James C. Paulson is an American biochemist and biologist known for his work in glycobiology. Career A graduate of MacMurray College and University of Illinois at Urbana–Champaign (M.S., Ph.D.), Paulson was a faculty member and vice-chair of the Department of Biological Chemistry at UCLA School of Medicine (now David Geffen School of Medicine at UCLA) from 1978-1990. In 1996, he began working for Cytel Corporation, where he was vice president, chief scientific officer, and member of the Board of Directors. In 1999, he joined the full-time faculty of The Scripps Research Institute. In 2001, he became principal researcher and founding director of the National Institutes of Health-funded Consortium for Functional Glycomics. In 2013, he was appointed chair of the institute's Department of Cell and Molecular Biology. From August 2014 to September 2015, he was the institute's acting president and CEO. Paulson is currently Cecil H. and Ida Green Professor and co-chair of Department of ...
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Biochemistry
Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all areas of the life sciences are being uncovered and developed through biochemical methodology and research. Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis which allows biological molecules to give rise to the processes that occur within living cells and between cells,Karp (2009), p. 2. in turn relating greatly to the understanding of tissues and organs, as well as organism structure and function.Miller (2012). p. 62. Biochemistry is closely related to molecular biology, which is the study of the molecular mechanisms of biological phenomena.As ...
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Utrecht University
Utrecht University (UU; nl, Universiteit Utrecht, formerly ''Rijksuniversiteit Utrecht'') is a public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2018, it had an enrollment of 31,801 students, and employed 7,191 faculty and staff. In 2018, 525 PhD degrees were awarded and 6,948 scientific articles were published. The 2018 budget of the university was €857 million. Utrecht University counts a number of distinguished scholars among its alumni and faculty, including 12 Nobel Prize laureates and 13 Spinoza Prize laureates. Utrecht University has been placed consistently in the top 100 universities in the world by prominent international ranking tables. The university is ranked as the best university in the Netherlands by the Shanghai Ranking of World Universities 2022, ranked 14th in Europe and 54th in the world. The university's motto is "Sol Iustitiae Illustra Nos", which means ''May the Sun of Righteous ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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21st-century American Biologists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ...
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National Research Council (Canada)
The National Research Council Canada (NRC; french: Conseil national de recherches Canada) is the primary national agency of the Government of Canada dedicated to science and technology research and development, research & development. It is the largest federal research & development organization in Canada. The Minister of Innovation, Science and Industry, Minister of Innovation, Science, and Economic Development (currently, François-Philippe Champagne) is responsible for the NRC. Mandate NRC is an Government agency, agency of the Government of Canada, and its mandate is set out in the ''National Research Council Act''. Under the Act, the NRC is responsible for: * Undertaking, assisting or promoting scientific and industrial research in fields of importance to Canada; * Providing vital scientific and technological services to the research and industrial communities; * Investigating standards and methods of measurement; * Working on the standardization and certification of sc ...
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Boston University
Boston University (BU) is a private research university in Boston, Massachusetts. The university is nonsectarian, but has a historical affiliation with the United Methodist Church. It was founded in 1839 by Methodists with its original campus in Newbury, Vermont, before moving to Boston in 1867. The university now has more than 4,000 faculty members and nearly 34,000 students, and is one of Boston's largest employers. It offers bachelor's degrees, master's degrees, doctorates, and medical, dental, business, and law degrees through 17 schools and colleges on three urban campuses. The main campus is situated along the Charles River in Boston's Fenway-Kenmore and Allston, Massachusetts, Allston neighborhoods, while the Boston University Medical Campus is located in Boston's South End, Boston, South End neighborhood. The Fenway campus houses the Wheelock College of Education and Human Development, formerly Wheelock College, which merged with BU in 2018. BU is a member of the Bo ...
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Protein Structure Initiative
The Protein Structure Initiative (PSI) was a USA based project that aimed at accelerating discovery in structural genomics and contribute to understanding biological function. Funded by the U.S. National Institute of General Medical Sciences (NIGMS) between 2000 and 2015, its aim was to reduce the cost and time required to determine three-dimensional protein structures and to develop techniques for solving challenging problems in structural biology, including membrane proteins. Over a dozen research centers have been supported by the PSI for work in building and maintaining high-throughput structural genomics pipelines, developing computational protein structure prediction methods, organizing and disseminating information generated by the PSI, and applying high-throughput structure determination to study a broad range of important biological and biomedical problems. The project has been organized into three separate phases. The first phase of the Protein Structure Initiative (PSI- ...
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American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ...
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Glycobiology (journal)
''Glycobiology'' is a monthly peer-reviewed scientific journal covering all aspects of the field of glycobiology and the official journal of the Society for Glycobiology. It is published by Oxford University Press. The journal was established in September 1990. It publishes primary research on the "biological functions of glycans, including glycoproteins, glycolipids, proteoglycans and free oligosaccharides, and on proteins that specifically interact with glycans." Abstracting and indexing The journal is indexed in Index Medicus/PubMed/MEDLINE, Index Veterinarius, CAB Abstracts, Biological Abstracts, BIOSIS Previews, Current Contents/Life Sciences, ProQuest, Science Citation Index, and others. According to the Journal Citation Reports, its 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in ...
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Bijvoet Center For Biomolecular Research
The Bijvoet Centre for Biomolecular Research is a research institute at Utrecht University. The Bijvoet Centre performs research on the relation between the structure and function of biomolecules, including proteins and lipids, which play a role in biological processes such as regulation, interaction and recognition. The Bijvoet Centre houses advanced infrastructures for the analysis of proteins and other biomolecules using NMR, X-ray crystallography, electron microscopy and mass spectrometry. The institute is named after famous Dutch chemist Johannes Martin Bijvoet, who worked at Utrecht University. History Utrecht University and the Netherlands Foundation for Chemical Research (SON, which later became the Chemical Sciences division of NWO, the Netherlands Organisation for Scientific Research) founded the Bijvoet Centre for Biomolecular Research as a joint research institute on March 25, 1988. The goal was to create a centre for research and expertise in structural biology with ...
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MacMurray College
MacMurray College was a private college in Jacksonville, Illinois. Its enrollment in fall 2015 was 570. Founded in 1846, the college closed in May 2020. History Although founded in 1846 by a group of Methodist clergymen as the Illinois Conference Female Academy, the first class was not held until 1848. Since its beginnings, the college was affiliated with the United Methodist Church. It was one of the oldest institutions of higher education originally for women in the United States. The school was renamed the Illinois Conference Female College in 1851, with the name changed again to Illinois Female College in 1863 and Illinois Woman's College in 1899. The name was changed to MacMurray College for Women in 1930 to honor James E. MacMurray, who was an Illinois state senator, president of Acme Steel Corporation in Chicago, and college trustee whose commitment led to a substantial increase in the college's facilities and endowment in the late 1920s and 1930s. The institution re ...
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Glycomics
Glycomics is the comprehensive study of glycomes (the entire complement of sugars, whether free or present in more complex molecules of an organism), including genetic, physiologic, pathologic, and other aspects. Glycomics "is the systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology. The term glycomics is derived from the chemical prefix for sweetness or a sugar, "glyco-", and was formed to follow the ''omics'' naming convention established by genomics (which deals with genes) and proteomics (which deals with proteins). Challenges *The complexity of sugars: regarding their structures, they are not linear instead they are highly branched. Moreover, glycans can be modified (modified sugars), this increases its complexity. *Complex biosynthetic pathways for glycans. *Usually glycans are found either bound to protein (glycoprotein) or conjugated with lipids (glycolipids). *Unlike genomes, glycans are highly dynamic. This area of r ...
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