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Israel Hanukoglu
Israel Hanukoglu ( tr, İsrael Hanukoğlu) is a Turkish-born Israeli scientist. He is a full professor of biochemistry and molecular biology at Ariel University and former science and technology adviser to the prime minister of Israel (1996–1999). He is founder of Israel Science and Technology Directory. Education Elementary and high school education Israel Hanukoglu attended :tr:Şişli Terakki Lisesi in Istanbul until the end of junior high school. In ninth grade, he switched to Atatürk Erkek Lisesi in Taksim, Istanbul, graduating in 1969. In his senior year, he was selected as a student for the American Field Service (AFS). As an AFS student, he attended Joseph A. Craig High School in Janesville, Wisconsin, and received his high-school diploma in 1970.Israel HanukogluCurriculum Vitae/ref> College education Israel Hanukoglu received his undergraduate degree ''cum laude'' with double majors in biology and psychology and a minor in political science from the Hebrew Univers ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neal L
Neal (Neil) is a given masculine name and surname of Gaelic and Irish origin. The name is an Anglicisation of the Irish Niall which is of disputed derivation. The Irish name may be derived from words meaning "cloud", "passionate", "victory", "honour" or "champion". As a surname, Neil is traced back to Niall of the Nine Hostages who was an Irish king and eponymous ancestor of the Uí Néill and MacNeil kindred. Most authorities cite the meaning of Neal in the context of a surname as meaning champion. Surname *Abbie Neal (1918–2004), American country music entertainer * Adam Neal (born 1990), English rugby league player *Alice B. Neal (1828–1863), American writer *Arthur Neal (1903–1982), English footballer *Blaine Neal (born 1978), American relief pitcher in Major League Baseball *Bob Neal (Atlanta sportscaster) (born 1942), American sports broadcaster *Bob Neal (Cleveland sportscaster) (1916–1983), American sports broadcaster * Charles Lincoln Neal (also known as "Link" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Steroid Hormones
A steroid hormone is a steroid that acts as a hormone. Steroid hormones can be grouped into two classes: corticosteroids (typically made in the adrenal cortex, hence ''cortico-'') and sex steroids (typically made in the gonads or placenta). Within those two classes are five types according to the receptors to which they bind: glucocorticoids and mineralocorticoids (both corticosteroids) and androgens, estrogens, and progestogens (sex steroids). Vitamin D derivatives are a sixth closely related hormone system with homologous receptors. They have some of the characteristics of true steroids as receptor ligands. Steroid hormones help control metabolism, inflammation, immune functions, salt and water balance, development of sexual characteristics, and the ability to withstand injury and illness. The term steroid describes both hormones produced by the body and artificially produced medications that duplicate the action for the naturally occurring steroids. Synthesis The natural ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Damon Runyon Cancer Research Foundation
The Damon Runyon Cancer Research Foundation (Damon Runyon) is an American not-for-profit cancer research organization focused on "discovering the talent to discover the cure". The organization states that its goals are to: "identify the best and brightest early career scientists in cancer research, accelerate the translation of scientific discoveries into new diagnostic tools and treatments, and to enable risk-taking on bold new ideas". The organization was founded in 1946 by media personality Walter Winchell in New York City, New York, under the name Damon Runyon Cancer Memorial Fund in memory of his colleague and friend Damon Runyon, a newspaperman and author. History Almost immediately after Runyon's passing on December 10, 1946, Winchell went on the air and asked his audience for contributions to cancer research: Mr. and Mrs. United States! A very dear friend of mine a great newspaperman, a great writer, and a very great guy Damon Runyon, was killed this week by Americ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Perspiration
Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals. Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distributed over much of the body and are responsible for secreting the watery, brackish sweat most often triggered by excessive body temperature. The apocrine sweat glands are restricted to the armpits and a few other areas of the body and produce an odorless, oily, opaque secretion which then gains its characteristic odor from bacterial decomposition. In humans, sweating is primarily a means of thermoregulation, which is achieved by the water-rich secretion of the eccrine glands. Maximum sweat rates of an adult can be up to 2–4 liters per hour or 10–14 liters per day (10–15 g/min·m2), but is less in children prior to puberty. Evaporation of sweat from the skin surface has a cooling effect due to evaporative cooling. Hence, in hot weather ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ASIC
An application-specific integrated circuit (ASIC ) is an integrated circuit (IC) chip customized for a particular use, rather than intended for general-purpose use, such as a chip designed to run in a digital voice recorder or a high-efficiency video codec. Application-specific standard product (ASSP) chips are intermediate between ASICs and industry standard integrated circuits like the 7400 series or the 4000 series. ASIC chips are typically fabricated using metal-oxide-semiconductor (MOS) technology, as MOS integrated circuit chips. As feature sizes have shrunk and design tools improved over the years, the maximum complexity (and hence functionality) possible in an ASIC has grown from 5,000 logic gates to over 100 million. Modern ASICs often include entire microprocessors, memory blocks including ROM, RAM, EEPROM, flash memory and other large building blocks. Such an ASIC is often termed a SoC (system-on-chip). Designers of digital ASICs often use a hardware description ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SCNN1B
The SCNN1B gene encodes for the β subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1A, SCNN1G, and SCNN1D. ENaC is expressed in epithelial cells and is different from the voltage-gated sodium channel that is involved in the generation of action potentials in neurons. The abbreviation for the genes encoding for voltage-gated sodium channel starts with three letters: SCN. In contrast to these sodium channels, ENaC is constitutively active and is not voltage-dependent. The second N in the abbreviation (SCNN1A) represents that these are NON-voltage-gated channels. In most vertebrates, sodium ions are the major determinant of the osmolarity of the extracellular fluid. ENaC allows transfer of sodium ions across the epithelial cell membrane in so-called "tight-epithelia" that have low permeability. The flow of sodium ions acr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SCNN1A
The SCNN1A gene encodes for the α subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous subunits α, β, and γ or δ, β, and γ. The other ENAC subunits are encoded by SCNN1B, SCNN1G, and SCNN1D. ENaC is expressed in epithelial cells and is different from the voltage-gated sodium channel that is involved in the generation of action potentials in neurons. The abbreviation for the genes encoding for voltage-gated sodium channel starts with three letters: SCN. In contrast to these sodium channels, ENaC is constitutively active and is not voltage-dependent. The second N in the abbreviation (SCNN1A) represents that these are NON-voltage-gated channels. In most vertebrates, sodium ions are the major determinant of the osmolarity of the extracellular fluid. ENaC allows transfer of sodium ions across the epithelial cell membrane in so-called "tight-epithelia" that have low permeability. The flow of sodium ions acr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tel Aviv University
Tel Aviv University (TAU) ( he, אוּנִיבֶרְסִיטַת תֵּל אָבִיב, ''Universitat Tel Aviv'') is a public research university in Tel Aviv, Israel. With over 30,000 students, it is the largest university in the country. Located in northwest Tel Aviv, the university is the center of teaching and research of the city, comprising 9 faculties, 17 teaching hospitals, 18 performing arts centers, 27 schools, 106 departments, 340 research centers, and 400 laboratories. Tel Aviv University originated in 1956 when three education units merged to form the university. The original 170-acre campus was expanded and now makes up 220 acres (89 hectares) in Tel Aviv's Ramat Aviv neighborhood. History TAU's origins date back to 1956, when three research institutes: the Tel Aviv School of Law and Economics (established in 1935), the Institute of Natural Sciences (established in 1931), and the Academic Institute of Jewish Studies (established in 1954) – joined to form Tel Aviv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aaron Hanukoglu
According to Abrahamic religions, Aaron ''′aharon'', ar, هارون, Hārūn, Greek (Septuagint): Ἀαρών; often called Aaron the priest ()., group="note" ( or ; ''’Ahărōn'') was a prophet, a high priest, and the elder brother of Moses. Knowledge of Aaron, along with his brother Moses, exclusively comes from religious texts, such as the Hebrew Bible, Bible and the Quran. The Hebrew Bible relates that, unlike Moses, who grew up in the Egyptian royal court, Aaron and his elder sister Miriam remained with their kinsmen in the eastern border-land of Egypt ( Goshen). When Moses first confronted the Egyptian king about the enslavement of the Israelites, Aaron served as his brother's spokesman ("prophet") to the Pharaoh (). Part of the Law given to Moses at Sinai granted Aaron the priesthood for himself and his male descendants, and he became the first High Priest of the Israelites. Aaron died before the Israelites crossed the Jordan river. According to the Book of Numbe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jerusalem
Jerusalem (; he, יְרוּשָׁלַיִם ; ar, القُدس ) (combining the Biblical and common usage Arabic names); grc, Ἱερουσαλήμ/Ἰεροσόλυμα, Hierousalḗm/Hierosóluma; hy, Երուսաղեմ, Erusałēm. is a city in Western Asia. Situated on a plateau in the Judaean Mountains between the Mediterranean Sea, Mediterranean and the Dead Sea, it is one of the List of oldest continuously inhabited cities, oldest cities in the world and is considered to be a holy city for the three major Abrahamic religions: Judaism, Christianity, and Islam. Both Israelis and Palestinians claim Jerusalem as their Capital city, capital, as Israel maintains its primary governmental institutions there and the State of Palestine ultimately foresees it as its seat of power. Because of this dispute, Status of Jerusalem, neither claim is widely recognized internationally. Throughout History of Jerusalem, its long history, Jerusalem has been destroyed at least twice, Sie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ACTH
Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms. Deficiency of ACTH is an indicator of secondary adrenal insufficiency (suppressed production of ACTH due to an impairment of the pituitary gland or hypothalamus, cf. hypopituitarism) or tertiary adrenal insufficiency (disease of the hypothalamus, with a decrease in the release of corticotropin releasing hormone (CRH)). Conversely, chronically elevated ACTH levels occur in primary adren ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rossmann Fold
The Rossmann fold is a tertiary fold found in proteins that bind nucleotides, such as enzyme cofactors FAD, NAD+, and NADP+. This fold is composed of alternating beta strands and alpha helical segments where the beta strands are hydrogen bonded to each other forming an extended beta sheet and the alpha helices surround both faces of the sheet to produce a three-layered sandwich. The classical Rossmann fold contains six beta strands whereas Rossmann-like folds, sometimes referred to as Rossmannoid folds, contain only five strands. The initial beta-alpha-beta (bab) fold is the most conserved segment of the Rossmann fold. The motif is named after Michael Rossmann who first noticed this structural motif in the enzyme lactate dehydrogenase in 1970 and who later observed that this was a frequently occurring motif in nucleotide binding proteins. Rossmann and Rossmannoid fold proteins are extremely common. They make up 20% of proteins with known structures in the Protein Data Bank, and a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
