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Integrated Nanolitre System
The integrated nanoliter system is a measuring, separating, and mixing device that is able to measure fluids to the nanoliter, mix different fluids for a specific product, and separate a solution into simpler solutions. Burns, Mark A., Brian N. Johnson, Sundaresh N. Brahmasandra, Kalyan Handique, James R. Webster, Madhavi Krishnan, Timoth S. Sammacro, Piu M. Man, Darren Jones, Dylan Heldsinger, Carlos H. Mastrangelo, and David T. Burke"An Integrated Nanoliter DNA Analysis Device" American Association for the Advancement of Science, January 29, 2013 All features of the integrated nanoliter system are specifically designed for controlling very small volume of liquid (referred as microfluidic solutions). The integrated nanoliter system's scalability depends on what type of processing method the system is based on (refer as technology platform) with each processing method having its advantages and disadvantages. Possible uses for the integrated nanoliter system are in controlling biolog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanoliter
The litre (international spelling) or liter (American English spelling) (SI symbols L and l, other symbol used: ℓ) is a metric unit of volume. It is equal to 1 cubic decimetre (dm3), 1000 cubic centimetres (cm3) or 0.001 cubic metre (m3). A cubic decimetre (or litre) occupies a volume of (see figure) and is thus equal to one-thousandth of a cubic metre. The original French metric system used the litre as a base unit. The word ''litre'' is derived from an older French unit, the '' litron'', whose name came from Byzantine Greek—where it was a unit of weight, not volume—via Late Medieval Latin, and which equalled approximately 0.831 litres. The litre was also used in several subsequent versions of the metric system and is accepted for use with the SI,Bureau International des Poids et Me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrohydrodynamics
Electrohydrodynamics (EHD), also known as electro-fluid-dynamics (EFD) or electrokinetics, is the study of the dynamics of electrically charged fluids. It is the study of the motions of ionized particles or molecules and their interactions with electric fields and the surrounding fluid. The term may be considered to be synonymous with the rather elaborate electrostrictive hydrodynamics. ESHD covers the following types of particle and fluid transport mechanisms: electrophoresis, electrokinesis, dielectrophoresis, electro-osmosis, and electrorotation. In general, the phenomena relate to the direct conversion of electrical energy into kinetic energy, and ''vice versa''. In the first instance, shaped electrostatic fields (ESF's) create hydrostatic pressure (HSP, or motion) in dielectric media. When such media are fluids, a flow is produced. If the dielectric is a vacuum or a solid, no flow is produced. Such flow can be directed against the electrodes, generally to move the elect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microarray
A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silicon thin-film cell—that assays (tests) large amounts of biological material using high-throughput screening miniaturized, multiplexed and parallel processing and detection methods. The concept and methodology of microarrays was first introduced and illustrated in antibody microarrays (also referred to as antibody matrix) by Tse Wen Chang in 1983 in a scientific publication and a series of patents. The "gene chip" industry started to grow significantly after the 1995 ''Science Magazine'' article by the Ron Davis and Pat Brown labs at Stanford University. With the establishment of companies, such as Affymetrix, Agilent, Applied Microarrays, Arrayjet, Illumina, and others, the technology of DNA microarrays has become the most sophisticated and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latency (engineering)
Latency, from a general point of view, is a time delay between the cause and the effect of some physical change in the system being observed. Lag, as it is known in gaming circles, refers to the latency between the input to a simulation and the visual or auditory response, often occurring because of network delay in online games. Latency is physically a consequence of the limited velocity at which any physical interaction can propagate. The magnitude of this velocity is always less than or equal to the speed of light. Therefore, every physical system with any physical separation (distance) between cause and effect will experience some sort of latency, regardless of the nature of the stimulation at which it has been exposed to. The precise definition of latency depends on the system being observed or the nature of the simulation. In communications, the lower limit of latency is determined by the medium being used to transfer information. In reliable two-way communication syst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microscopic
The microscopic scale () is the scale of objects and events smaller than those that can easily be seen by the naked eye, requiring a lens (optics), lens or microscope to see them clearly. In physics, the microscopic scale is sometimes regarded as the scale between the macroscopic scale and the quantum realm, quantum scale. Microscopic units and measurements are used to classify and describe very small objects. One common microscopic length scale unit is the micrometre (also called a ''micron'') (symbol: μm), which is one millionth of a metre. History Whilst compound microscopes were first developed in the 1590s, the significance of the microscopic scale was only truly established in the 1600s when Marcello Malpighi, Marcello Malphigi and Antonie van Leeuwenhoek microscopically observed frog lungs and microorganisms. As microbiology was established, the significance of making scientific observations at a microscopic level increased. Published in 1665, Robert Hooke’s book Mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chaotic Mixing
In chaos theory and fluid dynamics, chaotic mixing is a process by which flow tracers develop into complex fractals under the action of a fluid flow. The flow is characterized by an exponential growth of fluid filaments. Even very simple flows, such as the blinking vortex, or finitely resolved wind fields can generate exceptionally complex patterns from initially simple tracer fields. The phenomenon is still not well understood and is the subject of much current research. Context of chaotic advection Fluid flows Two basic mechanisms are responsible for fluid mixing: diffusion and advection. In liquids, molecular diffusion alone is hardly efficient for mixing. Advection, that is the transport of matter by a flow, is required for better mixing. The fluid flow obeys fundamental equations of fluid dynamics (such as the conservation of mass and the conservation of momentum) called Navier–Stokes equations. These equations are written for the Eulerian velocity field rather than ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Advection
In the field of physics, engineering, and earth sciences, advection is the transport of a substance or quantity by bulk motion of a fluid. The properties of that substance are carried with it. Generally the majority of the advected substance is also a fluid. The properties that are carried with the advected substance are conserved properties such as energy. An example of advection is the transport of pollutants or silt in a river by bulk water flow downstream. Another commonly advected quantity is energy or enthalpy. Here the fluid may be any material that contains thermal energy, such as water or air. In general, any substance or conserved, extensive quantity can be advected by a fluid that can hold or contain the quantity or substance. During advection, a fluid transports some conserved quantity or material via bulk motion. The fluid's motion is described mathematically as a vector field, and the transported material is described by a scalar field showing its distribution ov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reagent
In chemistry, a reagent ( ) or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms ''reactant'' and ''reagent'' are often used interchangeably, but reactant specifies a substance ''consumed'' in the course of a chemical reaction. ''Solvents'', though involved in the reaction mechanism, are usually not called reactants. Similarly, ''catalysts'' are not consumed by the reaction, so they are not reactants. In biochemistry, especially in connection with enzyme-catalyzed reactions, the reactants are commonly called substrates. Definitions Organic chemistry In organic chemistry, the term "reagent" denotes a chemical ingredient (a compound or mixture, typically of inorganic or small organic molecules) introduced to cause the desired transformation of an organic substance. Examples include the Collins reagent, Fenton's reagent, and Grignard reagents. Analytical chemistry In analytical chemistry, a reagent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flow Network
In graph theory, a flow network (also known as a transportation network) is a directed graph where each edge has a capacity and each edge receives a flow. The amount of flow on an edge cannot exceed the capacity of the edge. Often in operations research, a directed graph is called a network, the vertices are called nodes and the edges are called arcs. A flow must satisfy the restriction that the amount of flow into a node equals the amount of flow out of it, unless it is a source, which has only outgoing flow, or sink, which has only incoming flow. A network can be used to model traffic in a computer network, circulation with demands, fluids in pipes, currents in an electrical circuit, or anything similar in which something travels through a network of nodes. Definition A network is a graph , where is a set of vertices and is a set of 's edges – a subset of – together with a non-negative function , called the capacity function. Without loss of generality, we may assume that ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Structural Robustness
Robustness is the ability of a structure to withstand events like fire, explosions, impact or the consequences of human error, without being damaged to an extent disproportionate to the original causeas defined in EN 1991-1-7 of the Accidental Actions Eurocode. A structure designed and constructed to be robust should not suffer from disproportionate collapse (progressive collapse) under accidental loading. Buildings of some kinds, especially large-panel systems and precast concrete buildings, are disproportionately more susceptible to collapse; others, such as in situ cast concrete structures, are disproportionately less susceptible. The method employed in making a structure robust will typically depend on and be tailored to the kind of structure it is, as in steel framed building structural robustness is typically achieved through appropriately designing the system of connections between the frame's constituents. Design considerations Three alternative measures are used, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Valves
A valve is a device or natural object that regulates, directs or controls the flow of a fluid (gases, liquids, fluidized solids, or slurries) by opening, closing, or partially obstructing various passageways. Valves are technically fittings, but are usually discussed as a separate category. In an open valve, fluid flows in a direction from higher pressure to lower pressure. The word is derived from the Latin ''valva'', the moving part of a door, in turn from ''volvere'', to turn, roll. The simplest, and very ancient, valve is simply a freely hinged flap which swings down to obstruct fluid (gas or liquid) flow in one direction, but is pushed up by the flow itself when the flow is moving in the opposite direction. This is called a check valve, as it prevents or "checks" the flow in one direction. Modern control valves may regulate pressure or flow downstream and operate on sophisticated automation systems. Valves have many uses, including controlling water for irrigation, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Micelles
A micelle () or micella () (plural micelles or micellae, respectively) is an aggregate (or supramolecular assembly) of surfactant amphipathic lipid molecules dispersed in a liquid, forming a colloid, colloidal suspension (also known as associated colloidal system). A typical micelle in aqueous solution, water forms an aggregate with the hydrophilic "head" regions in contact with surrounding solvent, sequestering the hydrophobic single-tail regions in the micelle centre. This phase is caused by the Lipid bilayer phase behavior, packing behavior of single-tail lipids in a lipid bilayer, bilayer. The difficulty filling all the volume of the interior of a bilayer, while accommodating the area per head group forced on the molecule by the hydration of the lipid head group, leads to the formation of the micelle. This type of micelle is known as a normal-phase micelle (oil-in-water micelle). Inverse micelles have the head groups at the centre with the tails extending out (water-in-oil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
