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Index Case
The index case or patient zero is the first documented patient in a disease epidemic within a population, or the first documented patient included in an epidemiological study. It can also refer to the first case of a condition or syndrome (not necessarily contagious) to be described in the medical literature, whether or not the patient is thought to be the first person affected. An index case can achieve the status of a "classic" case study in the literature, as did Phineas Gage, the first known person to exhibit a definitive personality change as a result of a brain injury. Term The index case may or may not indicate the source of the disease, the possible spread, or which reservoir holds the disease in between outbreaks, but may bring awareness of an emerging outbreak. Earlier cases may or may not be found and are labeled primary or coprimary, secondary, tertiary, etc. The term primary case can only apply to infectious diseases that spread from human to human, and refers to t ...
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Patient
A patient is any recipient of health care services that are performed by healthcare professionals. The patient is most often ill or injured and in need of treatment by a physician, nurse, optometrist, dentist, veterinarian, or other health care provider. Etymology The word patient originally meant 'one who suffers'. This English noun comes from the Latin word ', the present participle of the deponent verb, ', meaning 'I am suffering,' and akin to the Greek verb (', to suffer) and its cognate noun (). This language has been construed as meaning that the role of patients is to passively accept and tolerate the suffering and treatments prescribed by the healthcare providers, without engaging in shared decision-making about their care. Outpatients and inpatients An outpatient (or out-patient) is a patient who attends an outpatient clinic with no plan to stay beyond the duration of the visit. Even if the patient will not be formally admitted with a note as an outpa ...
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The Wall Street Journal
''The Wall Street Journal'' is an American business-focused, international daily newspaper based in New York City, with international editions also available in Chinese and Japanese. The ''Journal'', along with its Asian editions, is published six days a week by Dow Jones & Company, a division of News Corp. The newspaper is published in the broadsheet format and online. The ''Journal'' has been printed continuously since its inception on July 8, 1889, by Charles Dow, Edward Jones, and Charles Bergstresser. The ''Journal'' is regarded as a newspaper of record, particularly in terms of business and financial news. The newspaper has won 38 Pulitzer Prizes, the most recent in 2019. ''The Wall Street Journal'' is one of the largest newspapers in the United States by circulation, with a circulation of about 2.834million copies (including nearly 1,829,000 digital sales) compared with '' USA Today''s 1.7million. The ''Journal'' publishes the luxury news and lifestyle magazi ...
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Haiti
Haiti (; ht, Ayiti ; French: ), officially the Republic of Haiti (); ) and formerly known as Hayti, is a country located on the island of Hispaniola in the Greater Antilles archipelago of the Caribbean Sea, east of Cuba and Jamaica, and south of The Bahamas and the Turks and Caicos Islands. It occupies the western three-eighths of the island which it shares with the Dominican Republic. To its south-west lies the small Navassa Island, which is claimed by Haiti but is disputed as a United States territory under federal administration."Haiti"
''Encyclopædia Britannica''.
Haiti is in size, the third largest country in the by area, and has an estimated population of 11.4 million, making it the ...
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Africa
Africa is the world's second-largest and second-most populous continent, after Asia in both cases. At about 30.3 million km2 (11.7 million square miles) including adjacent islands, it covers 6% of Earth's total surface area and 20% of its land area.Sayre, April Pulley (1999), ''Africa'', Twenty-First Century Books. . With billion people as of , it accounts for about of the world's human population. Africa's population is the youngest amongst all the continents; the median age in 2012 was 19.7, when the worldwide median age was 30.4. Despite a wide range of natural resources, Africa is the least wealthy continent per capita and second-least wealthy by total wealth, behind Oceania. Scholars have attributed this to different factors including geography, climate, tribalism, Scramble for Africa, colonialism, the Cold War, neocolonialism, lack of democracy, and corruption. Despite this low concentration of wealth, recent economic expansion and the large and young ...
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Genetic Analysis
Genetic analysis is the overall process of studying and researching in fields of science that involve genetics and molecular biology. There are a number of applications that are developed from this research, and these are also considered parts of the process. The base system of analysis revolves around general genetics. Basic studies include identification of genes and inherited disorders. This research has been conducted for centuries on both a large-scale physical observation basis and on a more microscopic scale. Genetic analysis can be used generally to describe methods both used in and resulting from the sciences of genetics and molecular biology, or to applications resulting from this research. Genetic analysis may be done to identify genetic/inherited disorders and also to make a differential diagnosis in certain somatic diseases such as cancer. Genetic analyses of cancer include detection of mutations, fusion genes, and DNA copy number changes. History of genetic analys ...
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Proceedings Of The National Academy Of Sciences Of The United States Of America
''Proceedings of the National Academy of Sciences of the United States of America'' (often abbreviated ''PNAS'' or ''PNAS USA'') is a peer-reviewed multidisciplinary scientific journal. It is the official journal of the National Academy of Sciences, published since 1915, and publishes original research, scientific reviews, commentaries, and letters. According to ''Journal Citation Reports'', the journal has a 2021 impact factor of 12.779. ''PNAS'' is the second most cited scientific journal, with more than 1.9 million cumulative citations from 2008 to 2018. In the mass media, ''PNAS'' has been described variously as "prestigious", "sedate", "renowned" and "high impact". ''PNAS'' is a delayed open access journal, with an embargo period of six months that can be bypassed for an author fee (hybrid open access). Since September 2017, open access articles are published under a Creative Commons license. Since January 2019, ''PNAS'' has been online-only, although print issues are ...
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Homosexual Men
Gay men are male homosexuals. Some bisexual and homoromantic men may also dually identify as gay, and a number of young gay men also identify as queer. Historically, gay men have been referred to by a number of different terms, including '' inverts'' and '' uranians''. Gay men continue to face significant discrimination in large parts of the world, particularly in most of Asia and Africa. In the United States, many gay men still face discrimination in their daily lives, though some openly gay men have reached national success and prominence. In Europe, Xavier Bettel currently serves as the prime minister of Luxembourg; Leo Varadkar serves as the Taoiseach and head of the Government of Ireland (he had previously served as Taoiseach (Prime Minister) from June 2017 to June 2020); and from 2011 to 2014, Elio Di Rupo served as Prime Minister of Belgium. For a time, the term ''gay'' was used as a synonym for anything related to homosexual men. For example, the term '' ga ...
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Gay Bathhouse
A gay bathhouse, also known as a gay sauna or a gay steambath (uncommonly known as a gay spa), is a commercial space for gay, bisexual, and other men to have sex with men. In gay slang, a bathhouse may be called just "the baths", "the sauna", or "the tubs". In general, a gay bath is used for having sexual activity rather than only bathing. Bathhouses offering similar services for women are rare, but some men's bathhouses occasionally have a "lesbian" or "women only" night. Some, such as Hawks PDX, offer so-called "bisexual" nights, where anyone is welcome regardless of gender. Bathhouses vary considerably in size and amenities – from small establishments with 10 or 20 rooms and a handful of lockers to multi-story saunas with a variety of room styles or sizes and several steam baths, hot tubs, and sometimes swimming pools. Most have a steam room (or wet sauna), dry sauna, showers, lockers, and small private rooms. In some countries, bathhouses are "membership only" (for ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic ma ...
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William Darrow
William Darrow is a professor of public health at Florida International University. Before accepting a position at FIU in August 1994, Darrow served as Chief of the Behavioral and Prevention Research Branch, Division of STD/HIV Prevention, at the National Center for Prevention Services of the Centers for Disease Control and Prevention (CDC). Darrow has published over 100 scientific papers in professional journals, books, and research monographs. His role in the discovery of the AIDS virus, HIV, was described in Randy Shilts' 1987 book ''And the Band Played On''. Darrow also appeared in "The Zero Factor," part one of the four-part documentary, ''A Time of AIDS'', which was shown on the Discovery Channel. At the CDC, Darrow's work primarily focused on the social variables of sexually transmitted diseases, especially among homosexual men. In 1981, his focus shifted from condom use and diseases such as syphilis and gonorrhea to HIV/AIDS. Since then, Darrow has devoted his study an ...
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Epidemic
An epidemic (from Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics of infectious diseases are generally caused by several factors including a significant change in the ecology of the areal population (e.g., increased stress maybe additional reason or increase in the density of a vector species), the introduction of an emerging pathogen to an areal population (by movement of pathogen or host) or an unexpected genetic change that is in the pathogen reservoir. Generally, epidemics concerns with the patterns of infectious disease spread. An epidemic may occur when host immunity to either an established pathogen or newly emerging novel pathogen is suddenly reduced below that found in the endemic equilibrium and the transmission threshold is exceeded. For example, in meningococcal infections, an attack rate in excess of ...
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AIDS
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with Cachexia, unintended weight loss. HIV is #Transmission, spread primarily by unprotected sex (including anal sex, anal and vaginal sex), contaminated blood transfusions, hypodermic needles, ...
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