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Implantable Cardioverter-defibrillator
An implantable cardioverter-defibrillator (ICD) or automated implantable cardioverter defibrillator (AICD) is a device implantable inside the body, able to perform defibrillation, and depending on the type, cardioversion and pacing of the heart. The ICD is the first-line treatment and prophylactic therapy for patients at risk for sudden cardiac death due to ventricular fibrillation and ventricular tachycardia. "AICD" was trademarked by the Boston Scientific corporation, so the more generic "ICD" is preferred terminology. Current device batteries last about six to ten years; with advances in technology (batteries with more capacity or potentially rechargeable batteries) it may be possible to increase this well past ten years. The lead (the electrical cable connecting the device to the heart) has a much longer average longevity but can incur various types of malfunction, specifically insulation failure or fracture of the conductor, and require replacement. The process of ...
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Guidant Corporation
Guidant Corporation, part of Boston Scientific and Abbott Labs, designs and manufactures artificial cardiac pacemakers, implantable cardioverter-defibrillators, stents, and other cardiovascular medical products. Their company headquarters is located in Indianapolis, Indiana. Their main competitors are Medtronic, St. Jude Medical, and Johnson and Johnson. History In February 1972, Cardiac Pacemakers, Inc. (CPI) of St. Paul, Minnesota was formed. CPI was a highly successful start up venture, increasing sales from zero in 1972 to over $47 million and highly profitable when it was acquired by Eli Lilly in 1978 for $127 million. In 1977 Eli Lilly & Co. buys IVAC of San Diego (a manufacturer of medical pumps and other hospital equipment) for $60.5 million. In 1980, Eli Lilly & Co. acquires Physio-Control of Redmond, WA. and Advanced Cardiovascular Systems of Santa Clara, CA 984(balloon dilatation catheters and guidewires) along with Devices for Vascular Intervention(DVI) of Redwood ...
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Circulation (journal)
''Circulation'' is a scientific journal published by Lippincott Williams & Wilkins for the American Heart Association. The journal publishes articles related to research in and the practice of cardiovascular diseases, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in applied (translational) and basic research. Its 2020 impact factor is 29.690, ranking it third among journals in the Cardiac and Cardiovascular Systems category and first in the Peripheral Vascular Disease category.2020 Journal Citation Reports (Clarivate Analytics, 2021) Articles become open access after a 12-month embargo period. 2008 saw the appearance of six subspecialty journals. The first edition of ''Circulation: Arrhythmia and Electrophysiology'' appeared in April 2008, followed by an edition dedicated to heart failure in May titled ''Circulation: Heart Failure''. The remaining four journals launched once per month from July through October ...
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Defibrillator
Defibrillation is a treatment for life-threatening cardiac arrhythmias, specifically ventricular fibrillation (V-Fib) and non-perfusing ventricular tachycardia (V-Tach). A defibrillator delivers a dose of electric current (often called a ''counter-shock'') to the heart. Although not fully understood, this process depolarizes a large amount of the heart muscle, ending the arrhythmia. Subsequently, the body's natural pacemaker in the sinoatrial node of the heart is able to re-establish normal sinus rhythm. A heart which is in asystole (flatline) cannot be restarted by a defibrillator, but would be treated by cardiopulmonary resuscitation (CPR). In contrast to defibrillation, synchronized electrical cardioversion is an electrical shock delivered in synchrony to the cardiac cycle. Although the person may still be critically ill, cardioversion normally aims to end poorly perfusing cardiac arrhythmias, such as supraventricular tachycardia. Defibrillators can be external, transvenou ...
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Bernard Lown
Bernard Lown (June 7, 1921February 16, 2021) was a Lithuanian-American cardiologist and inventor. Lown was the original developer of the direct current defibrillator for cardiac resuscitation, and the cardioverter for correcting rapid disordered heart rhythms. He introduced a new use for the drug lidocaine to control heartbeat disturbances. Throughout his medical career, Lown focused on two major medical challenges: the problem of sudden cardiac death and the role of psychological stress on the cardiovascular system. His investigations led to many medical break-throughs, among them the coronary care unit. His work made possible and safe much of modern cardiac surgery, as well as a host of other innovations. In 1985, Lown accepted the Nobel Peace Prize on behalf of the International Physicians for the Prevention of Nuclear War, an organization he co-founded with Soviet cardiologist Yevgeny Chazov, who later was Minister Of Health of the USSR. Lown was Professor of Cardiology Em ...
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Alois Langer
Alois A. Langer (born February 24, 1945 in Pittsburgh, Pennsylvania) is an American biomedical engineer best known as one of the co-inventors of the Implantable Cardioverter Defibrillator (ICD). Langer was inducted into the National Inventors Hall of Fame in 2002 for his contribution to developing the ICD. He studied electrical engineering at the Massachusetts Institute of Technology and completed his Ph.D. thesis at Carnegie Mellon University. In 1972, Langer became the chief biomedical engineer at MedRad Inc. and started work on the ICD project. In 1980, he oversaw the final testing and implantation of the device into a human patient. In 1990, Langer founded Cardiac Telecom Corporation and engaged in the development and marketing of telephonic cardiac monitoring systems. Langer currently lives in Forest Hills, Pennsylvania and works part-time as a Consultant. Early life and education Alois A. Langer, son of Westinghouse researcher and inventor also named Alois Langer, was born a ...
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Morton Mower
Morton Maimon Mower (January 31, 1933 – April 25, 2022) was an American cardiologist specializing in electrophysiology and the co-inventor of the automatic implantable cardioverter defibrillator. He served in several professional capacities at Sinai Hospital and Cardiac Pacemakers Inc. In 1996, he became the chairman and chief executive officer of Mower Research Associates. He was inducted into the National Inventors Hall of Fame in 2002 for the development of the automatic implantable cardioverter defibrillator with Michel Mirowski in the 1970s. He continued his research in the biomechanical engineering laboratories at Johns Hopkins University. Early life Morton Mower was born in Baltimore and raised in Frederick, Maryland, the son of Pauline Maimon and Robert Mower. His family was Jewish. His father was a shoe repairman and his mother, a homemaker, raised three children. During his summers while in grade school, Mower worked at his Uncle Sam's salt-water bathhouses in Atl ...
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Michel Mirowski
Michel Mirowski (October 14, 1924 – March 26, 1990) was a physician who helped develop the implantable cardioverter-defibrillator (ICD). Born in Warsaw, Poland, he practiced medicine in Israel before coming to Sinai Hospital in Baltimore, Maryland. While there he collaborated with Dr. Morton Mower and later Dr. Stephen Heilman's artificial pacemaker company to develop the first implantable cardioverter-defibrillator. Early life Mirowski was born as Mordechai Frydman on October 14, 1924, in Warsaw. When Nazi Germany invaded Poland in the fall of 1939, his father renamed him as Mieczysław Mirowski to try to protect him from the anti-Semitism of the time. Later, his French wife, Anna, would call him Michel, by which he became known. To escape the Nazis, Mirowski fled to Ukraine, and for the next five years survived under the most appalling conditions. By 1944 he was an officer in a Polish regiment and returned to Poland where, as the war ended, he registered as a medical stu ...
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Baltimore
Baltimore ( , locally: or ) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526. Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Co ...
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Sinai Hospital (Maryland)
Sinai Hospital is an American private hospital based in Baltimore, Maryland, that was founded in 1866 as the Hebrew Hospital and Asylum. It is now a Jewish-sponsored teaching hospital that provides care for patients in the greater Baltimore City, Baltimore County and surrounding communities. The implantable cardioverter-defibrillator (ICD) was invented here by the team of Dr. Michel Mirowski, Dr. Morton Mower, M. Stephen Heilman, and Alois Langer who are all in the National Inventors Hall of Fame for their achievement. Since 1998, Sinai Hospital has been a part of the LifeBridge Health system, which also runs Northwest Hospital in Randallstown, Carroll Hospital in Westminster, Levindale Hebrew Geriatric Center and Nursing Home (which is across the street from Sinai), Rubin Institute for Advanced Orthopedics, several medical office buildings in the Baltimore area, and a health and fitness club called LifeBridge Health & Fitness, located in Pikesville, Maryland. Sinai Hospita ...
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Pericardium
The pericardium, also called pericardial sac, is a double-walled sac containing the heart and the roots of the great vessels. It has two layers, an outer layer made of strong connective tissue (fibrous pericardium), and an inner layer made of serous membrane (serous pericardium). It encloses the pericardial cavity, which contains pericardial fluid, and defines the middle mediastinum. It separates the heart from interference of other structures, protects it against infection and blunt trauma, and lubricates the heart's movements. The English name originates from the Ancient Greek prefix "''peri-''" (περί; "around") and the suffix "''-cardion''" (κάρδιον; "heart"). Anatomy The pericardium is a tough fibroelastic sac which covers the heart from all sides except at the cardiac root (where the great vessels join the heart) and the bottom (where only the serous pericardium exists to cover the upper surface of the central tendon of diaphragm). The fibrous perica ...
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Epicardium
The pericardium, also called pericardial sac, is a double-walled sac containing the heart and the roots of the great vessels. It has two layers, an outer layer made of strong connective tissue (fibrous pericardium), and an inner layer made of serous membrane (serous pericardium). It encloses the pericardial cavity, which contains pericardial fluid, and defines the middle mediastinum. It separates the heart from interference of other structures, protects it against infection and blunt trauma, and lubricates the heart's movements. The English name originates from the Ancient Greek prefix "''peri-''" (περί; "around") and the suffix "''-cardion''" (κάρδιον; "heart"). Anatomy The pericardium is a tough fibroelastic sac which covers the heart from all sides except at the cardiac root (where the great vessels join the heart) and the bottom (where only the serous pericardium exists to cover the upper surface of the central tendon of diaphragm). The fibrous pericard ...
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