Imjin Virus
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Imjin Virus
''Imjin thottimvirus'' (MJNV) is a single-stranded, enveloped, negative-sense RNA virus of the orthohantavirus genus in the Bunyavirales order. It is a newly identified hantavirus isolated from the lung tissues of Ussuri white-toothed shrews of the species ''Crocidura lasiura'' (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005. Virology Phylogenetic analyses demonstrates a common ancestry with '' Thottopalayam thottimvirus'' suggesting early evolutionary divergence. It is still unknown if MJNV is pathogenic for humans. MJNV has been shown to be a genetically unique hantavirus. Multiple strains have been isolated from the lung tissues of Ussuri white-toothed shrews captured between 2004 and 2010. Partial M- and L-segment sequences from lung tissues of 12 of 37 (32.4%) anti-MJNV IgG antibody-positive shrews revealed that the 12 MJNV strains differed by 0–12.2% and 0–2.3% at the n ...
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Orthohantavirus
''Orthohantavirus'' is a genus of single-stranded, enveloped, negative-sense RNA viruses in the family ''Hantaviridae'' within the order ''Bunyavirales''. Members of this genus may be called orthohantaviruses or simply hantaviruses. Orthohantaviruses typically cause chronic asymptomatic infection in rodents. Humans may become infected with hantaviruses through contact with rodent urine, saliva, or feces. Some strains cause potentially fatal diseases in humans, such as hantavirus hemorrhagic fever with renal syndrome (HFRS), or hantavirus pulmonary syndrome (HPS), also known as hantavirus cardiopulmonary syndrome (HCPS), while others have not been associated with known human disease (e.g. Prospect Hill virus). HPS (HCPS) is a "rare respiratory illness associated with the inhalation of aerosolized rodent excreta (urine and feces) contaminated by hantavirus particles." Human infections of hantaviruses have almost entirely been linked to human contact with rodent excrement; however, ...
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Bunyavirales
''Bunyavirales'' is an order of segmented negative-strand RNA viruses with mainly tripartite genomes. Member viruses infect arthropods, plants, protozoans, and vertebrates. It is the only order in the class ''Ellioviricetes''. The name ''Bunyavirales'' derives from Bunyamwera, where the original type species ''Bunyamwera orthobunyavirus'' was first discovered. ''Ellioviricetes'' is named in honor of late virologist Richard M. Elliott for his early work on bunyaviruses. Bunyaviruses belong to the fifth group of the Baltimore classification system, which includes viruses with a negative-sense, single-stranded RNA genome. They have an enveloped, spherical virion. Though generally found in arthropods or rodents, certain viruses in this order occasionally infect humans. Some of them also infect plants. In addition, there is a group of bunyaviruses whose replication is restricted to arthropods and is known as insect-specific bunyaviruses. A majority of bunyaviruses are vector-borne ...
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Ussuri White-toothed Shrew
The Ussuri white-toothed shrew (''Crocidura lasiura'') is a species of musk shrew found on the mainland Northeast Asia Northeast Asia or Northeastern Asia is a geographical subregion of Asia; its northeastern landmass and islands are bounded by the Pacific Ocean. The term Northeast Asia was popularized during the 1930s by American historian and political scienti .... It is common and widespread, and is one of the largest shrews found in the region, with adult weight of . It should not be confused with the related Ussuri shrew (''Sorex mirabilis''). References External linksList of subspecies
Crocidura Mammals of Korea
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Soricomorpha
Soricomorpha (from Greek "shrew-form") is a formerly used taxon within the class of mammals. In the past it formed a significant group within the former order Insectivora. However, Insectivora was shown to be polyphyletic and various new orders were split off from it, including Afrosoricida (tenrecs, golden moles, otter shrews), Macroscelidea (elephant shrews), and Erinaceomorpha (hedgehogs and gymnures), with the four remaining extant and recent families of Soricomorpha shown here then being treated as a separate order. Insectivora was left empty and disbanded. Subsequently, Soricomorpha itself was shown to be paraphyletic, because Soricidae shared a more recent common ancestor with Erinaceidae than with other soricomorphs. The combination of Soricomorpha and Erinaceidae, referred to as order Eulipotyphla, has been shown to be monophyletic. Living members of the group range in size from the Etruscan shrew, at about 3.5 cm and 2 grams, to the Cuban solenodon, at about 32&n ...
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Crocidurinae
The white-toothed shrews or Crocidurinae are one of three subfamilies of the shrew family Soricidae. The outer layer of these shrews' teeth is white, unlike that of the red-toothed shrews. These species are typically found in Africa and southern Europe and Asia. This subfamily includes the largest shrew, the Asian house shrew, ''Suncus murinus'', at about 15 cm in length, and the smallest, the Etruscan shrew, ''Suncus etruscus'', at about 3.5 cm in length and 2 grams in weight. The latter is possibly the world's smallest extant mammal, although some give this title to the bumblebee bat. ''Crocidura'' contains the most species of any mammal genus. When young must be moved before they are independent, mother and young form a chain or "caravan" where each animal hangs on to the rear of the one in front. This behaviour has also been observed in some ''Sorex'' species. List of species Subfamily Crocidurinae *Genus ''Crocidura'' (white-toothed shrews) ** Mysterious shrew, ' ...
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Korean Demilitarized Zone
The Korean Demilitarized Zone (Korean: ; Hanbando Bimujang Jidae) is a strip of land running across the Korean Peninsula near the 38th parallel north. The demilitarized zone (DMZ) is a border barrier that divides the peninsula roughly in half. It was established to serve as a buffer zone between the countries of North Korea and South Korea under the provisions of the Korean Armistice Agreement in 1953, an agreement between North Korea, China, and the United Nations Command. The DMZ is long and about wide. There have been various incidents in and around the DMZ, with military and civilian casualties on both sides. Within the DMZ is a meeting point between the two nations, where negotiations take place: the small Joint Security Area (JSA) near the western end of the zone. Location The Korean Demilitarized Zone intersects but does not follow the 38th parallel north, which was the border before the Korean War. It crosses the parallel on an angle, with the west end of ...
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Republic Of Korea
South Korea, officially the Republic of Korea (ROK), is a country in East Asia, constituting the southern part of the Korean Peninsula and sharing a land border with North Korea. Its western border is formed by the Yellow Sea, while its eastern border is defined by the Sea of Japan. South Korea claims to be the sole legitimate government of the entire peninsula and adjacent islands. It has a population of 51.75 million, of which roughly half live in the Seoul Capital Area, the fourth most populous metropolitan area in the world. Other major cities include Incheon, Busan, and Daegu. The Korean Peninsula was inhabited as early as the Lower Paleolithic period. Its first kingdom was noted in Chinese records in the early 7th century BCE. Following the unification of the Three Kingdoms of Korea into Silla and Balhae in the late 7th century, Korea was ruled by the Goryeo dynasty (918–1392) and the Joseon dynasty (1392–1897). The succeeding Korean Empire (1897–1910) was ...
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Thottopalayam Thottimvirus
''Thottopalayam thottimvirus'', formerly ''Thottapalayam virus'', (TMPV) is single-stranded, enveloped, negative-sense RNA virus species of the genus '' Thottimvirus'' in the ''Bunyavirales'' order. It is the first hantavirus to be isolated from a shrew. It was discovered in India in 1964. Natural reservoir TPMV was first isolated from an Asian house shrew (''Suncus murinus'') in India in 1964. It is part of a group of hantaviruses which are hosted by shrews instead of rodents. These shrew-borne ''thottimviruses'' are not known to cause any known disease in humans, unlike the similar and related ''orthohantaviruses'' including Andes and Hantaan viruses, which cause lethal hemorrhagic fevers. TPMV was first isolated in Asian house shrews in Wenzhou of Zhejiang province, China. Virology Phylogenetic analysis has shown that Thottapalayam virus, and its closely related strains, is unique and forms a distinct lineage, unrelated to other hantaviruses. The closest hantavirus to ...
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Sangassou Virus
''Sangassou orthohantavirus'' (SANGV) is single-stranded, negative-sense RNA virus species of the genus ''Orthohantavirus'' in the ''Bunyavirales'' order. It was first isolated in an African wood mouse ('' Hylomyscus simus'') in the forest in Guinea, West Africa in 2010. It is named for the village near where the mouse was trapped. It is the first indigenous Murinae-associated African hantavirus to be discovered. Genome The virus genome consists of three segments of negative-stranded RNA; the large (L) segment encodes the viral RNA-dependent RNA polymerase, the medium (M) segment encodes the envelope glycoproteins Gn and Gc (cotranslationally cleaved from a glycoprotein precursor), and the small (S) segment encodes the nucleocapsid (N) protein. Renal syndrome In rodents, hantavirus produces a chronic infection with no adverse sequelae. In humans, hantavirus produces two major clinical syndromes: hemorrhagic fever or pulmonary syndrome. European, Asian, and African rodent-b ...
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Sweating Sickness
Sweating sickness, also known as the sweats, English sweating sickness, English sweat or ''sudor anglicus'' in Latin, was a mysterious and contagious disease that struck England and later continental Europe in a series of epidemics beginning in 1485. The last outbreak occurred in 1551, after which the disease apparently vanished. The onset of symptoms was sudden, with death often occurring within hours. Sweating sickness epidemics were unique compared with other disease outbreaks of the time: whereas other epidemics were typically urban and long-lasting, cases of sweating sickness spiked and receded very quickly, and heavily affected rural populations. Its cause remains unknown, although it has been suggested that an unknown species of hantavirus was responsible. Signs and symptoms John Caius was a physician in Shrewsbury in 1551, when an outbreak occurred, and he described the symptoms and signs of the disease in ''A Boke or Counseill Against the Disease Commonly Called the ...
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1993 Four Corners Hantavirus Outbreak
The 1993 Four Corners hantavirus outbreak was an outbreak of hantavirus that caused the first known human cases of hantavirus disease in the United States. It occurred within the Four Corners region – the geographic intersection of the U.S. states of Utah, Colorado, New Mexico, and Arizona – of the Southwestern United States in mid-1993. This region is largely occupied by Native American tribal lands, including the Hopi, Ute, Zuni, and Navajo reservations, from which many of the cases were reported. The virus killed 13 people — half of those it infected, for a mortality rate of 50%. The cause of the outbreak was found to be a previously unknown species of hantavirus, which was responsible for a new form of illness known as hantavirus pulmonary syndrome or HPS. The virus is carried by deer mice. Originally referred to as "Four Corners virus", "Muerto Canyon virus", and "Convict Creek virus", it was later named Sin Nombre virus. Transmission to humans was found to have ...
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