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Izon Science
Izon Science Ltd. provides solutions for the isolation and measurement of biological and synthetic nano-sized particles such as extracellular vesicles, lipid nano particles, viruses and virus-like particles, and various synthetic particles being developed for drug delivery. Their main instruments are based on principles of size exclusion chromatography and tunable resistive pulse sensing, together which are used in thousands of research institutes and universities around the world. Izon’s size-exclusion chromatography columns and related solutions are also used by diagnostics companies focused on developing extracellular vesicle biomarkers. Izon Science’s headquarters are located in Addington (Christchurch, New Zealand), and the company has a wide global distribution network, facilitated by collaborations with distributors, and by sales and technical support offices in Medford, Massachusetts (United States), Portland, Oregon (United States), Lyon (France) and Brisbane (Austr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Private Limited Company
A private limited company is any type of business entity in "private" ownership used in many jurisdictions, in contrast to a publicly listed company, with some differences from country to country. Examples include the '' LLC'' in the United States, ''private company limited by shares'' in the United Kingdom, '' GmbH'' in Germany and Austria, ''société à responsabilité limitée'' in France, and ''sociedad de responsabilidad limitada'' in the Spanish-speaking world. The benefit of having a private limited company is that there is limited liability. However, shares can only be sold to shareholders in the business, which means that it can be difficult to liquidate such a company. Abbreviations Albania In Albania a limited liability company ( sq, Shoqëri me përgjegjësi të kufizuar Sh.p.k) is a commercial company founded by persons of physical or judicial status, who are not liable for the company and personally bear losses only up to the outstanding contribution agreeme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanotechnology
Nanotechnology, also shortened to nanotech, is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm). This definition reflects the fact that quantum mechanical effects are important at this quantum-realm scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanoparticle
A nanoparticle or ultrafine particle is usually defined as a particle of matter that is between 1 and 100 nanometres (nm) in diameter. The term is sometimes used for larger particles, up to 500 nm, or fibers and tubes that are less than 100 nm in only two directions. At the lowest range, metal particles smaller than 1 nm are usually called atom clusters instead. Nanoparticles are usually distinguished from microparticles (1-1000 µm), "fine particles" (sized between 100 and 2500 nm), and "coarse particles" (ranging from 2500 to 10,000 nm), because their smaller size drives very different physical or chemical properties, like colloidal properties and ultrafast optical effects or electric properties. Being more subject to the brownian motion, they usually do not sediment, like colloidal particles that conversely are usually understood to range from 1 to 1000 nm. Being much smaller than the wavelengths of visible light (400-700 nm), nano ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extracellular Vesicle
Extracellular vesicles (EVs) are lipid bilayer-delimited particles that are naturally released from almost all types of cell but, unlike a cell, cannot replicate. EVs range in diameter from near the size of the smallest physically possible unilamellar liposome (around 20-30 nanometers) to as large as 10 microns or more, although the vast majority of EVs are smaller than 200 nm. EVs can be divided according to size and synthesis route into Exosomes, microvesicles and apoptotic bodies. They carry a cargo of proteins, nucleic acids, lipids, metabolites, and even organelles from the parent cell. Most cells that have been studied to date are thought to release EVs, including some archaeal, bacterial, fungal, and plant cells that are surrounded by cell walls. A wide variety of EV subtypes have been proposed, defined variously by size, biogenesis pathway, cargo, cellular source, and function, leading to a historically heterogenous nomenclature including terms like exosomes and ecto ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Size-exclusion Chromatography
Size-exclusion chromatography (SEC), also known as molecular sieve chromatography, is a chromatographic method in which molecules in solution are separated by their size, and in some cases molecular weight. It is usually applied to large molecules or macromolecular complexes such as proteins and industrial polymers. Typically, when an aqueous solution is used to transport the sample through the column, the technique is known as gel-filtration chromatography, versus the name gel permeation chromatography, which is used when an organic solvent is used as a mobile phase. The chromatography column is packed with fine, porous beads which are commonly composed of dextran, agarose, or polyacrylamide polymers. The pore sizes of these beads are used to estimate the dimensions of macromolecules. SEC is a widely used polymer characterization method because of its ability to provide good molar mass distribution (Mw) results for polymers. Applications The main application of gel-filtration chr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tunable Resistive Pulse Sensing
Tunable Resistive Pulse Sensing (TRPS) is a single-particle technique used to measure the size, concentration and zeta potential of particles as they pass through a size-tunable nanopore. The technique adapts the principle of resistive pulse sensing, which monitors current flow through an aperture, combined with the use of tunable nanopore technology, allowing the passage of ionic current and particles to be regulated by adjusting the pore size. Technique Particles crossing a pore are detected one at a time as a transient change in the ionic current flow, which is denoted as a blockade event with its amplitude denoted as the blockade magnitude. As blockade magnitude is proportional to particle size, accurate particle sizing can be achieved after calibration with a known standard. Nanopore-based detection allows particle-by-particle assessment of complex mixtures. Optimization of pore size to particle size, by adjusting the stretch of the pore, can improve measurement accurac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Christchurch
Christchurch ( ; mi, Ōtautahi) is the largest city in the South Island of New Zealand and the seat of the Canterbury Region. Christchurch lies on the South Island's east coast, just north of Banks Peninsula on Pegasus Bay. The Avon River / Ōtākaro flows through the centre of the city, with an urban park along its banks. The city's territorial authority population is people, and includes a number of smaller urban areas as well as rural areas. The population of the urban area is people. Christchurch is the second-largest city by urban area population in New Zealand, after Auckland. It is the major urban area of an emerging sub-region known informally as Greater Christchurch. Notable smaller urban areas within this sub-region include Rangiora and Kaiapoi in Waimakariri District, north of the Waimakariri River, and Rolleston and Lincoln in Selwyn District to the south. The first inhabitants migrated to the area sometime between 1000 and 1250 AD. They hunted moa, which led ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Medical Center Utrecht
The University Medical Center Utrecht (UMCU; Dutch: ''Universitair Medisch Centrum Utrecht'') is the main hospital of the city of Utrecht, Netherlands. It is affiliated with the Utrecht University. Since the foundation of the university in 1636 an academic hospital has existed in various forms. Nowadays the UMC Utrecht comprises the academic hospital, the faculty of Medicine as well as the Wilhelmina Children's hospital. In total approximately 10,000 people work at the UMCU including medical staff, nursing staff, residents, support personnel and researchers, making it one of the largest hospitals in the Netherlands. __TOC__ Special units * Neurosurgery * Cardiothoracic surgery *Radiation oncology unit * Neonatal and pediatric surgery and intensive care * Pediatric oncology * Level I trauma center Adjacent to the UMCU lies the Central Military Hospital, or CMH, for military personnel. The UMCU also features a Major Incident Hospital (Dutch: ''Calamiteitenhospitaal''). This faci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
VU University Medical Center
VU University Medical Center Amsterdam ( nl, VU Medisch Centrum or VUmc) is the university hospital affiliated with the Vrije Universiteit Amsterdam. It is rated one of the best academic medical centers in the country in terms of patient care and research. It is located next to Amsterdam's A10 ringway in the southwestern part of the city, next to the campus of the Vrije Universiteit and close to Schiphol airport. On 30 October 2015, researchers at the VUmc Cancer Center Amsterdam reported developing a blood test that, from a single drop of blood, can diagnose cancer with a probability of 97%, and about 6-8% probability of a false diagnosis, in healthy patients. In October 2015 the VUmc got the first ''MRIdian'' system in Europe, currently the most advanced radiation therapy system to treat tumors, because the system has a built-in MRI scanner to aim the radiation optimally. History VU University Medical Center Amsterdam was opened in 1964 as the Academic Hospital of the Vrije U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mayo Clinic
The Mayo Clinic () is a nonprofit American academic medical center focused on integrated health care, education, and research. It employs over 4,500 physicians and scientists, along with another 58,400 administrative and allied health staff, across three major campuses: Rochester, Minnesota; Jacksonville, Florida; and Phoenix/Scottsdale, Arizona. The practice specializes in treating difficult cases through tertiary care and destination medicine. It is home to the top-15 ranked Mayo Clinic Alix School of Medicine in addition to many of the highest regarded residency education programs in the United States. It spends over $660 million a year on research and has more than 3,000 full-time research personnel. William Worrall Mayo settled his family in Rochester in 1864 and opened a sole proprietorship medical practice that evolved under his sons, Will and Charlie Mayo, along with practice partners Stinchfield, Graham, Plummer, Millet, Judd, and Balfour, into Mayo Clinic. Toda ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
