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Israel Kleiner (biochemist)
Israel Simon Kleiner (April 8, 1885 – June 15, 1966) was a biochemist whose work helped lead to the discovery of insulin. Kleiner's grandparents Israel and Eva (Meyer) were Jews who came to America from Bavaria, Germany, in 1848. Born in New Haven, Connecticut, Kleiner was a member of the Congregation Mishkan Israel temple, where his uncle, city council member Charles Kleiner was president. Kleiner received his Ph.D. in biochemistry at Yale in 1909. From 1910, he worked as an assistant in physiology at the Rockefeller Institute until 1914, when he became an associate. In 1919 he was appointed as professor at the New York Homeopathic Medical College (later to become New York Medical College). Here he served as acting dean in 1921 and then as dean from 1922 to 1925. In 1935 he became professor of biochemistry, and from 1948 was the director of the department of biochemistry. On February 10, 1959, Kleiner was awarded the third annual Van Slyke award in Clinical Chemistry, at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the ''INS'' gene. It is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1885 Births
Events January–March * January 3– 4 – Sino-French War – Battle of Núi Bop: French troops under General Oscar de Négrier defeat a numerically superior Qing Chinese force, in northern Vietnam. * January 4 – The first successful appendectomy is performed by Dr. William W. Grant, on Mary Gartside. * January 17 – Mahdist War in Sudan – Battle of Abu Klea: British troops defeat Mahdist forces. * January 20 – American inventor LaMarcus Adna Thompson patents a roller coaster. * January 24 – Irish rebels damage Westminster Hall and the Tower of London with dynamite. * January 26 – Mahdist War in Sudan: Troops loyal to Mahdi Muhammad Ahmad conquer Khartoum; British commander Charles George Gordon is killed. * February 5 – King Leopold II of Belgium establishes the Congo Free State, as a personal possession. * February 9 – The first Japanese arrive in Hawaii. * February 16 – Charles Dow publishes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Place Of Death Missing
Place may refer to: Geography * Place (United States Census Bureau), defined as any concentration of population ** Census-designated place, a populated area lacking its own municipal government * "Place", a type of street or road name ** Often implies a dead end (street) or cul-de-sac * Place, based on the Cornish word "plas" meaning mansion * Place, a populated place, an area of human settlement ** Incorporated place (see municipal corporation), a populated area with its own municipal government * Location (geography), an area with definite or indefinite boundaries or a portion of space which has a name in an area Placenames * Placé, a commune in Pays de la Loire, Paris, France * Plače, a small settlement in Slovenia * Place (Mysia), a town of ancient Mysia, Anatolia, now in Turkey * Place, New Hampshire, a location in the United States * Place House, a 16th-century mansion largely remodelled in the 19th century, in Fowey, Cornwall * Place House, a 19th-century mansion o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Jews
American Jews or Jewish Americans are American citizens who are Jewish, whether by religion, ethnicity, culture, or nationality. Today the Jewish community in the United States consists primarily of Ashkenazi Jews, who descend from diaspora Jewish populations of Central and Eastern Europe and comprise about 90–95% of the American Jewish population. During the colonial era, prior to the mass immigration of Ashkenazi Jews, Sephardic Jews who arrived via Portugal represented the bulk of America's then-small Jewish population, and while their descendants are a Minority group, minority today, they, along with an array of other Jewish communities, represent the remainder of American Jews, including other more recent Sephardi Jews, Mizrahi Jews, Beta Israel, Beta Israel-Ethiopian Jews, Jewish ethnic divisions, various other ethnically Jewish communities, as well as a smaller number of Conversion to Judaism, converts to Judaism. The American Jewish community manifests a wide range ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American People Of German-Jewish Descent
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Biochemists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York Medical College Faculty
New is an adjective referring to something recently made, discovered, or created. New or NEW may refer to: Music * New, singer of K-pop group The Boyz Albums and EPs * ''New'' (album), by Paul McCartney, 2013 * ''New'' (EP), by Regurgitator, 1995 Songs * "New" (Daya song), 2017 * "New" (Paul McCartney song), 2013 * "New" (No Doubt song), 1999 *"new", by Loona from '' Yves'', 2017 *"The New", by Interpol from ''Turn On the Bright Lights'', 2002 Acronyms * Net economic welfare, a proposed macroeconomic indicator * Net explosive weight, also known as net explosive quantity * Network of enlightened Women, a conservative university women's organization * Next Entertainment World, a South Korean film distribution company Identification codes * Nepal Bhasa language ISO 639 language code * New Century Financial Corporation (NYSE stock abbreviation) * Northeast Wrestling, a professional wrestling promotion in the northeastern United States Transport * New Orleans Lakefront Ai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale Graduate School Of Arts And Sciences Alumni
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate colleg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientists From New Haven, Connecticut
A scientist is a person who conducts Scientific method, scientific research to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century in science, 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have Terminal degree, advanced degrees in an area of science and pursue careers in various Sector (economic), sectors of the economy such ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1966 Deaths
Events January * January 1 – In a coup, Colonel Jean-Bédel Bokassa takes over as military ruler of the Central African Republic, ousting President David Dacko. * January 3 – 1966 Upper Voltan coup d'état: President Maurice Yaméogo is deposed by a military coup in the Republic of Upper Volta (modern-day Burkina Faso). * January 10 ** Pakistani–Indian peace negotiations end successfully with the signing of the Tashkent Declaration, a day before the sudden death of Indian prime minister Lal Bahadur Shastri. ** Georgia House of Representatives, The House of Representatives of the US state of Georgia refuses to allow African-American representative Julian Bond to take his seat, because of his anti-war stance. ** A Commonwealth Prime Ministers' Conference convenes in Lagos, Nigeria, primarily to discuss Rhodesia. * January 12 – United States President Lyndon Johnson states that the United States should stay in South Vietnam until Communism, Communist aggression there is e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypoglycemia
Hypoglycemia, also called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L). Whipple's triad is used to properly identify hypoglycemic episodes. It is defined as blood glucose below 70 mg/dL (3.9 mmol/L), symptoms associated with hypoglycemia, and resolution of symptoms when blood sugar returns to normal. Hypoglycemia may result in headache, tiredness, clumsiness, trouble talking, confusion, fast heart rate, sweating, shakiness, nervousness, hunger, loss of consciousness, seizures, or death. Symptoms typically come on quickly. The most common cause of hypoglycemia is medications used to treat diabetes such as insulin, sulfonylureas, and biguanides. Risk is greater in diabetics who have eaten less than usual, recently exercised, or consumed alcohol. Other causes of hypoglycemia include severe illness, sepsis, kidney failure, liver disease, hormone deficiency, tumors such as insulinomas or non-B cell tumo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bavaria
Bavaria ( ; ), officially the Free State of Bavaria (german: Freistaat Bayern, link=no ), is a state in the south-east of Germany. With an area of , Bavaria is the largest German state by land area, comprising roughly a fifth of the total land area of Germany. With over 13 million inhabitants, it is second in population only to North Rhine-Westphalia, but due to its large size its population density is below the German average. Bavaria's main cities are Munich (its capital and largest city and also the third largest city in Germany), Nuremberg, and Augsburg. The history of Bavaria includes its earliest settlement by Iron Age Celtic tribes, followed by the conquests of the Roman Empire in the 1st century BC, when the territory was incorporated into the provinces of Raetia and Noricum. It became the Duchy of Bavaria (a stem duchy) in the 6th century AD following the collapse of the Western Roman Empire. It was later incorporated into the Holy Roman Empire, became an ind ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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