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Ion Beam Applications
IBA (Ion Beam Applications SA) is a medical technology company based in Louvain-la-Neuve. The company was founded in 1986 by Yves Jongen within the Cyclotron Research Center of the University of Louvain (UCLouvain) and became a university spin-off. It employs about 1500 people in 40 locations. The company developed cyclotrons and integrated proton therapy centers is active in the field of proton therapy, dosimetry, radiopharmacy solutions and industrial sterilisation. IBA installed its first proton therapy equipment for Boston's Massachusetts General Hospital in 2001, and for Philadelphia's Penn Hospital in 2009. It supplied equipment and services to Proton Partners International Rutherford Health was a private oncology provider founded by Mike Moran and Karol Sikora in 2015, with investment from Neil Woodford and the Wales Life Sciences Investment Fund, to develop proton therapy facilities in the United Kingdom and elsewhe ... which was developing three proton beam therapy ce ...
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Louvain-la-Neuve
Louvain-la-Neuve (, French for ''New Leuven''; wa, Li Noû Lovén) is a planned town in the municipality of Ottignies-Louvain-la-Neuve, Wallonia, Belgium, situated 30 km southeast of Brussels, in the province of Walloon Brabant. The town was built to house the Université catholique de Louvain (UCLouvain) which owns its entire territory; following the linguistic quarrels that took place in Belgium during the 1960s, and Flemish claims of discrimination at the Catholic University of Leuven, the institution was split into the Dutch language Katholieke Universiteit Leuven (KU Leuven), which remained in Leuven, and the Université catholique de Louvain. To a great extent, it still lives following the rhythms of the university that is its raison d'être. However, with the construction of ''L'Esplanade'' shopping complex, the '' Aula Magna'' exhibition centre and auditorium, a large cinema complex, and five museums, it is beginning to grow beyond its academic roots. History Langua ...
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Proton Therapy
In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam radiotherapy is that the dose of protons is deposited over a narrow range of depth; hence in minimal entry, exit, or scattered radiation dose to healthy nearby tissues. When evaluating whether to treat a tumor with photon or proton therapy, physicians may choose proton therapy if it is important to deliver a higher radiation dose to targeted tissues while significantly decreasing radiation to nearby organs at risk. The American Society for Radiation Oncology Model Policy for Proton Beam therapy says proton therapy is considered reasonable if sparing the surrounding normal tissue "cannot be adequately achieved with photon-based radiotherapy" and can benefit the patient. Like photon radiation therapy, proton therapy is often used in conjuncti ...
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Medical Technology Companies Of Belgium
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancie ...
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Proton Partners International
Rutherford Health was a private oncology provider founded by Mike Moran and Karol Sikora in 2015, with investment from Neil Woodford and the Wales Life Sciences Investment Fund, to develop proton therapy facilities in the United Kingdom and elsewhere. Until 2019 it was known as Proton Partners International. It went into liquidation in June 2022. According to major shareholder Schroders UK Public Private Trust, the company had pursued a "flawed expansion strategy ... from 2015 to 2019" leading to "a high and unsustainable cash burn". Proton therapy Rutherford Health ran proton therapy centres in Newport, Wales, Bedlington, Northumberland, Liverpool and Reading, Berkshire. Equipment and services were provided by Ion Beam Applications, Philips and Elekta. The Newport site was the first to open with construction starting in 2016. The Reading site cost £30 million and work began in December 2016, before opening in October 2018. The Bedlington site was opened in 2018. Funding included ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ...
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Sterilization (microbiology)
Sterilization refers to any process that removes, kills, or deactivates all forms of life (particularly microorganisms such as fungi, bacteria, spores, and unicellular eukaryotic organisms) and other biological agents such as prions present in or on a specific surface, object, or fluid. Sterilization can be achieved through various means, including heat, chemicals, irradiation, high pressure, and filtration. Sterilization is distinct from disinfection, sanitization, and pasteurization, in that those methods reduce rather than eliminate all forms of life and biological agents present. After sterilization, an object is referred to as being sterile or aseptic. Applications Foods One of the first steps toward modernized sterilization was made by Nicolas Appert, who discovered that application of heat over a suitable period slowed the decay of foods and various liquids, preserving them for safe consumption for a longer time than was typical. Canning of foods is an extension of the ...
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Radiopharmacy
Nuclear pharmacy, also known as radiopharmacy, involves preparation of radioactive materials for patient administration that will be used to diagnose and treat specific diseases in nuclear medicine. It generally involves the practice of combining a radionuclide tracer with a pharmaceutical component that determines the biological localization in the patient. Radiopharmaceuticals are generally not designed to have a therapeutic effect themselves, but there is a risk to staff from radiation exposure and to patients from possible contamination in production. Due to these intersecting risks, nuclear pharmacy is a heavily regulated field. The majority of diagnostic nuclear medicine investigations are performed using technetium-99m. History The concept of nuclear pharmacy was first described in 1960 by Captain William H. Briner while at the National Institutes of Health (NIH) in Bethesda, Maryland. Along with Mr. Briner, John E. Christian, who was a professor in the School of Pharmacy a ...
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Dosimetry
Radiation dosimetry in the fields of health physics and radiation protection is the measurement, calculation and assessment of the ionizing radiation dose absorbed by an object, usually the human body. This applies both internally, due to ingested or inhaled radioactive substances, or externally due to irradiation by sources of radiation. Internal dosimetry assessment relies on a variety of monitoring, bio-assay or radiation imaging techniques, whilst external dosimetry is based on measurements with a dosimeter, or inferred from measurements made by other radiological protection instruments. Dosimetry is used extensively for radiation protection and is routinely applied to monitor occupational radiation workers, where irradiation is expected, or where radiation is unexpected, such as in the aftermath of the Three Mile Island, Chernobyl or Fukushima radiological release incidents. The public dose take-up is measured and calculated from a variety of indicators such as ambient measure ...
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Cyclotron
A cyclotron is a type of particle accelerator invented by Ernest O. Lawrence in 1929–1930 at the University of California, Berkeley, and patented in 1932. Lawrence, Ernest O. ''Method and apparatus for the acceleration of ions'', filed: January 26, 1932, granted: February 20, 1934 A cyclotron accelerates charged particles outwards from the center of a flat cylindrical vacuum chamber along a spiral path. The particles are held to a spiral trajectory by a static magnetic field and accelerated by a rapidly varying electric field. Lawrence was awarded the 1939 Nobel Prize in Physics for this invention. The cyclotron was the first "cyclical" accelerator. The primary accelerators before the development of the cyclotron were electrostatic accelerators, such as the Cockcroft–Walton accelerator and Van de Graaff generator. In these accelerators, particles would cross an accelerating electric field only once. Thus, the energy gained by the particles was limited by the maximum elec ...
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Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ...
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University Spin-off
University spin-offs (also known as university spin-outs) are companies that transform technological inventions developed from university research that are likely to remain unexploited otherwise. They are a subcategory of research spin-offs. Prominent examples of university spin-offs are Genentech, Crucell, Lycos and Plastic Logic. In most countries, universities can claim the intellectual property (IP) rights on technologies developed in their laboratories. In the United States, the Bayh–Dole Act permits universities to pursue ownership of inventions made by researchers at their institutions using funding from the federal government, where previously federal research funding contracts and grants obligated inventors (wherever they worked) to assign the resulting IP to the government. This IP typically draws on patents or, in exceptional cases, copyrights. Therefore, the process of establishing the spin-off as a new corporation involves transferring the IP to the new corporation ...
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Université Catholique De Louvain
The Université catholique de Louvain (also known as the Catholic University of Louvain, the English translation of its French name, and the University of Louvain, its official English name) is Belgium's largest French-speaking university. It is located in Louvain-la-Neuve, which was expressly built to house the university, and Brussels, Charleroi, Mons, Tournai and Namur. Since September 2018, the university has used the branding UCLouvain, replacing the acronym UCL, following a merger with Saint-Louis University, Brussels. The original University of Louvain (''Universitas Lovaniensis'') was founded at the centre of the historic town of Leuven (or ''Louvain'') in 1425, and abolished by the law in 1797 making it the first university in Belgium and the Low Countries. This university was the centre of Baianism, Jansenism and Febronianism in Europe. A new university, the State University of Louvain, was founded in 1817 and abolished by the law in 1835. A new catholic universit ...
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