Injection Lipolysis
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Injection Lipolysis
Injection lipolysis is a controversial cosmetic procedure in which drug mixtures are injected into patients with the goal of destroying fat cells. This practice, using drugs generally based on phosphatidylcholine and deoxycholate (PCDC), evolved from the initial intravenous use of those drug formulations to treat blood disorders. While no placebo-controlled studies have demonstrated the safety or efficacy of this therapy, numerous retrospective studies of Lipostabil injections have reported the efficacy of this practice. The mixture is injected directly into the subcutaneous fat through multiple microinjections administered over multiple treatment sessions. The desired end result is the removal of localized fat deposits. History In 1966, investigators noted that the intravenous infusion of PC-containing solutions could remove fat emboli. Later, a drug formulation called Lipostabil containing 5% PC and 2.5% deoxycholate (DC) was approved in Germany and used in the treatment of fa ...
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Phosphatidylcholine
Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane. They are also a member of the lecithin group of yellow-brownish fatty substances occurring in animal and plant tissues. Dipalmitoyl phosphatidylcholine (a.k.a. lecithin) is a major component of pulmonary surfactant and is often used in the L/S ratio to calculate fetal lung maturity. While phosphatidylcholines are found in all plant and animal cells, they are absent in the membranes of most bacteria, including ''Escherichia coli''. Purified phosphatidylcholine is produced commercially. The name ''lecithin'' was derived from Greek λέκιθος, ''lekithos'' 'egg yolk' by Theodore Nicolas Gobley, a French chemist and pharmacist of the mid-19th century, who appli ...
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Deoxycholate
Deoxycholic acid is a bile acid. Deoxycholic acid is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. The two primary bile acids secreted by the liver are cholic acid and chenodeoxycholic acid. Bacteria metabolize chenodeoxycholic acid into the secondary bile acid lithocholic acid, and they metabolize cholic acid into deoxycholic acid. There are additional secondary bile acids, such as ursodeoxycholic acid. Deoxycholic acid is soluble in alcohol and acetic acid. When pure, it comes in a white to off-white crystalline powder form. Deoxycholic acid is available as a generic medication in the United States as of April 2021, sold under the brand name Kybella among others. Applications Deoxycholic acid has been used since its discovery in various fields of human medicine. In the human body deoxycholic acid is used in the emulsification of fats for absorption in the intestine. It has, in some countries (including Switzerland) been licensed ...
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Journal Of Cutaneous Medicine And Surgery
The ''Journal of Cutaneous Medicine and Surgery'' (abbreviated ''JCMS'') is a bimonthly peer-reviewed medical journal covering dermatology. It was established in 1996 and is published by SAGE Publications in collaboration with the Canadian Dermatology Association, of which it is the official journal. The editor-in-chief is Kirk Barber (University of Calgary). According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 2.092, ranking it 46th out of 69 journals in the category "Dermatology". References External links * Dermatology journals SAGE Publishing academic journals Publications established in 1996 English-language journals Bimonthly journals Academic journals associated with learned and prof ...
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American Society Of Plastic Surgeons
The American Society of Plastic Surgeons (ASPS) is the largest plastic surgery specialty organization in the world. Founded in 1931, the society is composed of surgeons certified by the American Board of Plastic Surgery or by the Royal College of Physicians and Surgeons of Canada who perform Plastic and Reconstructive surgery. ASPS comprises 93% of all board-certified plastic surgeons in the United States and has more than 8,000 plastic surgeons worldwide. ASPS publishes the plastic surgery journal, ''Plastic and Reconstructive Surgery ''Plastic and Reconstructive Surgery'' is a peer-reviewed medical journal and the official publication of the American Society of Plastic Surgeons. It covers all aspects of plastic and reconstructive surgery Reconstructive surgery is surgery p ...''. Research ASPS runs The Plastic Surgery Foundation (The PSF), which supports research by ASPS members through grants, awards and scholarships. The foundation also funds educational research program ...
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American Society For Aesthetic Plastic Surgery
ThAmerican Society for Aesthetic Plastic Surgery (ASAPS)is an organization of approximately 2,600 plastic surgeons worldwide devoted to the advancement of cosmetic surgery. Founded in 1967, their mission includes medical education, public education and patient advocacy. ASAPS sponsors scientific conferences throughout the year and offers Continuing Medical Education (CME) credits for various educational activities. U.S. members are certified by the American Board of Plastic Surgery (ABPS), an independent, non-profit organization. Canadian members are certified in plastic surgery by the Royal College of Physicians and Surgeons of Canada. Plastic surgeons from other countries outside the U.S. and Canada must be members of their national society in either the International Confederation for Plastic, Reconstructive and Aesthetic Surgery (IPRAS) or the International Society of Aesthetic Plastic Surgery (ISAPS). Besides certification, membership requires a plastic surgeon to regularly a ...
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American Society Of Dermatologic Surgery
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * Ba ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ...
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FDA Warning Letter
An FDA warning letter is an official message from the United States Food and Drug Administration (FDA) to a manufacturer or other organization that has violated some rule in a federally regulated activity. The FDA defines an FDA warning letter as: ... a correspondence that notifies regulated industry about violations that FDA has documented during its inspections or investigations. Typically, a Warning Letter notifies a responsible individual or firm that the Agency considers one or more products, practices, processes, or other activities to be in violation of the Federal Food, Drug, and Cosmetic Act (the Act), its implementing regulations and other federal statutes. Warning Letters should only be issued for violations of regulatory significance, i.e., those that may actually lead to an enforcement action if the documented violations are not promptly and adequately corrected. A Warning Letter is one of the Agency's principal means of achieving prompt voluntary compliance with the ...
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Medspa
A day spa is a business that provides a variety of services for the purpose of improving health, beauty, and relaxation through personal care treatments such as massages and facials. The number of day spas in the US almost doubled in the two years from 2002 to 2004, to 8,734, according to the International Spa Association, and by 2020 there were 21,560 spas across the United States, according to Statista. Differences from beauty salon and destination spa A day spa is different from a beauty salon, in that it contains facilities such as a sauna, pool, steam room, or whirlpool that guests may use in addition to their treatment. A day spa is also different from a destination spa, as no overnight accommodation is provided. In contrast, a destination spa offers similar services integrated into packages that may include diet, exercise programs, instruction on wellness, life coaching, yoga, tai chi, and accommodations in which participants reside for the duration of their stay. I ...
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Medicines And Healthcare Products Regulatory Agency
The Medicines and Healthcare products Regulatory Agency (MHRA) is an executive agency of the Department of Health and Social Care in the United Kingdom which is responsible for ensuring that medicines and medical devices work and are acceptably safe. The MHRA was formed in 2003 with the merger of the Medicines Control Agency (MCA) and the Medical Devices Agency (MDA). In April 2013, it merged with the National Institute for Biological Standards and Control (NIBSC) and was rebranded, with the MHRA identity being used solely for the regulatory centre within the group. The agency employs more than 1,200 people in London, York and South Mimms, Hertfordshire. Structure The MHRA is divided into three main centres: * MHRA Regulatory – the regulator for the pharmaceutical and medical devices industries * Clinical Practice Research Datalink – licences anonymised health care data to pharmaceutical companies, academics and other regulators for research * National Institute for Biolog ...
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Medical Protection Society
The Medical Protection Society (MPS) is one of the three UK mutual protection organisations for medical, dental and healthcare professionals. (Dentists are covered through its subsidiary company Dental Protection). It protects and supports the professional interests of more than 300,000 members around the world (including the United Kingdom, Ireland, Malaysia, Singapore, Hong Kong, South Africa, New Zealand plus the Caribbean and Bermuda). Members of MPS can benefit from access to indemnity, expert advice and peace of mind. Advisers are on hand to talk through a question or concern. MPS' in-house experts assist with the wide range of legal and ethical problems that arise from professional practice. This includes clinical negligence claims, complaints, medical and dental council inquiries, legal and ethical dilemmas, disciplinary procedures, inquests and fatal accident inquiries. MPS is not an insurance company. All the benefits of membership of MPS are discretionary as set out ...
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Medical Treatments
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ...
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