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Ian Wilmut
Sir Ian Wilmut, OBE FRS -- FMedSci FRSE (born 7 July 1944) is an English embryologist and Chair of the Scottish Centre for Regenerative Medicine at the University of Edinburgh. He is best known as the leader of the research group that in 1996 first cloned a mammal from an adult somatic cell, a Finnish Dorset lamb named Dolly. He was appointed OBE in 1999 for services to embryo development and knighted in the 2008 New Year Honours. He together with Keith Campbell and Shinya Yamanaka jointly received the 2008 Shaw Prize for Medicine and Life Sciences "for their works on the cell differentiation in mammals." Early life and education Wilmut was born in Hampton Lucy, Warwickshire, England. Wilmut's father, Leonard Wilmut, was a mathematics teacher who suffered from diabetes for fifty years, which eventually caused him to become blind. He was a student of the former Boys' High School, in Scarborough, where his father taught. Wilmut's early desire was to embark on a naval ...
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Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts and ...
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Shaw Prize
The Shaw Prize is an annual award presented by the Shaw Prize Foundation. Established in 2002 in Hong Kong, it honours "individuals who are currently active in their respective fields and who have recently achieved distinguished and significant advances, who have made outstanding contributions in academic and scientific research or applications, or who in other domains have achieved excellence. The award is dedicated to furthering societal progress, enhancing quality of life, and enriching humanity's spiritual civilization." The prize has been described as the "Nobel of the East". It was founded by Hong Kong entertainment mogul and philanthropist Run Run Shaw (邵逸夫). Award The prize consists of three awards in the fields of astronomy, life science and medicine, and mathematical sciences; it is not awarded posthumously. Nominations are submitted by invited individuals beginning each year in September. Winners are announced in the summer and receive the award at a cere ...
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Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ...
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Warwickshire
Warwickshire (; abbreviated Warks) is a county in the West Midlands region of England. The county town is Warwick, and the largest town is Nuneaton. The county is famous for being the birthplace of William Shakespeare at Stratford-upon-Avon and Victorian novelist George Eliot, (born Mary Ann Evans), at Nuneaton. Other significant towns include Rugby, Leamington Spa, Bedworth, Kenilworth and Atherstone. The county offers a mix of historic towns and large rural areas. It is a popular destination for international and domestic tourists to explore both medieval and more recent history. The county is divided into five districts of North Warwickshire, Nuneaton and Bedworth, Rugby, Warwick and Stratford-on-Avon. The current county boundaries were set in 1974 by the Local Government Act 1972. The historic county boundaries included Coventry, Sutton Coldfield and Solihull, as well as much of Birmingham and Tamworth. Geography Warwickshire is bordered by Leicestershire to the nort ...
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Shinya Yamanaka
is a Japanese stem cell researcher and a Nobel Prize laureate. He serves as the director of Center for iPS Cell (induced Pluripotent Stem Cell) Research and Application and a professor at the Institute for Frontier Medical Sciences at Kyoto University; as a senior investigator at the UCSF-affiliated Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisco (UCSF). Yamanaka is also a past president of the International Society for Stem Cell Research (ISSCR). He received the 2010 BBVA Foundation Frontiers of Knowledge Award in the biomedicine category, the 2011 Wolf Prize in Medicine with Rudolf Jaenisch, and the 2012 Millennium Technology Prize together with Linus Torvalds. In 2012, he and John Gurdon were awarded the Nobel Prize for Physiology or Medicine for the discovery that mature cells can be converted to stem cells. In 2013, he was awarded the $3 million Breakthrough Prize in Life Sciences for his work. ...
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Keith Campbell (biologist)
Keith Henry Stockman Campbell (23 May 1954 – 5 October 2012) was a British biologist who was a member of the team at Roslin Institute that in 1996 first cloned a mammal, a Finnish Dorset lamb named Dolly, from fully differentiated adult mammary cells. He was Professor of Animal Development at the University of Nottingham. In 2008, he received the Shaw Prize for Medicine and Life Sciences jointly with Ian Wilmut and Shinya Yamanaka for "their works on the cell differentiation in mammals". Education Campbell was born in Birmingham, England, to an English mother and Scottish father. He started his education in Perth, Scotland, but, when he was eight years old, his family returned to Birmingham, where he attended King Edward VI Camp Hill School for Boys. He obtained his Bachelor of Science degree in microbiology from the Queen Elizabeth College, University of London (now part of King's College London). In 1983 Campbell was awarded the Marie Curie Research Scholarship, which led ...
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New Year Honours 2008
The New Year Honours 2008 for the Commonwealth realms were announced on 29 December 2007, to celebrate the year passed and mark the beginning of 2008. The recipients of honours are displayed here as they were styled before their new honour, and arranged firstly by the country whose ministers advised the Queen on the appointments, then by honour, with classes (Knight, Knight Grand Cross, ''etc.'') and then divisions (Military, Civil, ''etc.'') as appropriate. United Kingdom Order of Companions of Honour (CH) * Sir Ian Murray McKellen, CBE, stage and screen actor, for services to drama and to equality. Knight Bachelor * John Michael Ashworth, for public service * John Irving Bell, Regius Professor of Medicine, University of Oxford and president, Academy of Medical Sciences, for services to medicine * John James Griffin Good, chairman, Edrington Group, for services to industry in Scotland * Patrick Hugh Haren, deputy chairman, Viridian Group Ltd, for services to the electricity in ...
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Finnish Dorset (sheep)
The Finn-Dorset or Finn Dorset is a British and Irish sheep, a cross-breed of the Finnsheep with the Dorset Horn. Dolly the sheep, first mammal to be cloned from an adult somatic cell A somatic cell (from Ancient Greek σῶμα ''sôma'', meaning "body"), or vegetal cell, is any biological cell forming the body of a multicellular organism other than a gamete, germ cell, gametocyte or undifferentiated stem cell. Such cells compo ..., was a Finn Dorset. References Sheep breeds Mammal hybrids {{sheep-stub ...
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Somatic Cell
A somatic cell (from Ancient Greek σῶμα ''sôma'', meaning "body"), or vegetal cell, is any biological cell forming the body of a multicellular organism other than a gamete, germ cell, gametocyte or undifferentiated stem cell. Such cells compose the body of an organism and divide through the process of binary fission and mitotic division. In contrast, gametes are cells that fuse during sexual reproduction, germ cells are cells that give rise to gametes, and stem cells are cells that can divide through mitosis and differentiate into diverse specialized cell types. For example, in mammals, somatic cells make up all the internal organs, skin, bones, blood and connective tissue, while mammalian germ cells give rise to spermatozoa and ova which fuse during fertilization to produce a cell called a zygote, which divides and differentiates into the cells of an embryo. There are approximately 220 types of somatic cell in the human body. Theoretically, these cells are not germ cells (t ...
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Cloned
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millions of years. It ...
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Scottish Centre For Regenerative Medicine
The Centre for Regenerative Medicine (CRM) is a stem cell research centre at the University of Edinburgh in Scotland, dedicated to the study and development of new regenerative treatments for human diseases. The centre forms part of the university's Institute for Regeneration and Repair and is part of the BioQuarter cluster at Little France. History The University of Edinburgh's history in stem cell research dates back to the early 1990s. Under the leadership of Austin Smith, the university's Centre for Genome Research became the first Institute of Stem Cell Research (ISCR) in the UK. The CRM was formed in 2008 as a merger of ISCR scientists with scientists from the University's College of Medicine and Veterinary Medicine, an initiative directed by Ian Wilmut. From 2008 to 2020, the centre had MRC status. Charles ffrench-Constant became the 2nd Director of CRM in 2010; he was succeeded by Stuart Forbes in 2015. , the CRM had attracted £55 million in research funding. R ...
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Embryologist
Embryology (from Greek ἔμβρυον, ''embryon'', "the unborn, embryo"; and -λογία, '' -logia'') is the branch of animal biology that studies the prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses. Additionally, embryology encompasses the study of congenital disorders that occur before birth, known as teratology. Early embryology was proposed by Marcello Malpighi, and known as preformationism, the theory that organisms develop from pre-existing miniature versions of themselves. Aristotle proposed the theory that is now accepted, epigenesis. Epigenesis is the idea that organisms develop from seed or egg in a sequence of steps. Modern embryology, developed from the work of Karl Ernst von Baer, though accurate observations had been made in Italy by anatomists such as Aldrovandi and Leonardo da Vinci in the Renaissance. Comparative embryology Preformationism and epigenesis As recently as the 18th century, the prevailin ...
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