HLA-A36
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HLA-A36
Distribution A36 is largely limited to Africa. Outside Africa, more than half of the populations have no A36 and the majority that do, have only trace levels. The exception is in Central/East Central Asia. This appears not to be coincidental. HLA DR3-DQ2 linkage and frequency indicates a strong possibility of a recent migration from either North or West Africa in which the DR3-DQ2 (notably DRB1*0302) and A*33-B*58 haplotype A haplotype ( haploid genotype) is a group of alleles in an organism that are inherited together from a single parent. Many organisms contain genetic material ( DNA) which is inherited from two parents. Normally these organisms have their DNA or ...s were carried into and redistributed from Central Asia into the surrounding populations. References {{HLA-A serotypes 3 ...
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HLA DR3-DQ2
HLA DR3-DQ2 is double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype. Certain HLA DR and DQ genes have known involvement in autoimmune diseases. DR3- DQ2, a multigene haplotype, stands out in prominence because it is a factor in several prominent diseases, namely coeliac disease and juvenile diabetes. In coeliac disease, the DR3-DQ2 haplotype is associated with highest risk for disease in first degree relatives, highest risk is conferred by DQA1*0501:DQB1*0201 homozygotes and semihomozygotes of DQ2, and represents the overwhelming majority of risk. HLA DR3-DQ2 encodes DQ2.5cis isoform of HLA-DQ, this isoform is described frequently as 'the DQ2 isoform', but in actuality there are two major DQ2 isoform. The DQ2.5 isoform, however, is many times more frequently associated with autoimmune disease, and as a result to contribution of DQ2.2 is often ignored. The frequency of both diseases changes with respect to both the envi ...
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Mossi People
Mossi may refer to: *Mossi people *Mossi language *Mossi Kingdoms * the Mossi, a Burkinabe variant of the Dongola horse *Mossi (given name) *Mossi (surname) See also *Mossie (other) *Mossy (other) Mossy may refer to: Places *Mossy, West Virginia, unincorporated community in Fayette County, West Virginia, United States Given names *Mossy Cade (born 1961), former professional American football player *Mossy Lawler (born 1980), rugby union pl ... * Mozzi (other) {{disambiguation, surname ...
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Burkina Faso
Burkina Faso (, ; , ff, 𞤄𞤵𞤪𞤳𞤭𞤲𞤢 𞤊𞤢𞤧𞤮, italic=no) is a landlocked country in West Africa with an area of , bordered by Mali to the northwest, Niger to the northeast, Benin to the southeast, Togo and Ghana to the south, and the Ivory Coast to the southwest. It has a population of 20,321,378. Previously called Republic of Upper Volta (1958–1984), it was renamed Burkina Faso by President Thomas Sankara. Its citizens are known as ''Burkinabè'' ( ), and its capital and largest city is Ouagadougou. The largest ethnic group in Burkina Faso is the Mossi people, who settled the area in the 11th and 13th centuries. They established powerful kingdoms such as the Ouagadougou, Tenkodogo, and Yatenga. In 1896, it was colonized by the French as part of French West Africa; in 1958, Upper Volta became a self-governing colony within the French Community. In 1960, it gained full independence with Maurice Yaméogo as president. Throughout the decades post in ...
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Beti People
Beti may refer to: People * Mongo Beti (1932–2001), Cameroonian writer * Beti George (born 1939), Welsh television and radio broadcaster * Beti Jones (1919–2006), Scottish social worker * Beti Kamya-Turwomwe (born 1955), Ugandan businesswoman and politician * Beti Rimac (born 1976), Croatian volleyball player * Beti Rhys (1907–2003), Welsh bookstore owner and author * Beti Sekulovski (born 1983), Australian tennis player Other uses * Béti, a sub-prefecture of Logone Occidental Region in Chad * Beti people, a Central African ethnic group * Beti language Beti is a group of Bantu languages, spoken by the Beti-Pahuin peoples who inhabit the rain forest regions of Cameroon, Republic of the Congo, Equatorial Guinea, Gabon Gabon (; ; snq, Ngabu), officially the Gabonese Republic (french: Rà ..., a group of Bantu languages in Central and West Africa * Beti language (Côte d'Ivoire) or Eotile, a nearly extinct Tano language * ''Beti'' (1969 film), an Indian, Hind ...
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Cameroon
Cameroon (; french: Cameroun, ff, Kamerun), officially the Republic of Cameroon (french: République du Cameroun, links=no), is a country in west-central Africa. It is bordered by Nigeria to the west and north; Chad to the northeast; the Central African Republic to the east; and Equatorial Guinea, Gabon and the Republic of the Congo to the south. Its coastline lies on the Bight of Biafra, part of the Gulf of Guinea and the Atlantic Ocean. Due to its strategic position at the crossroads between West Africa and Central Africa, it has been categorized as being in both camps. Its nearly 27 million people speak 250 native languages. Early inhabitants of the territory included the Sao civilisation around Lake Chad, and the Baka hunter-gatherers in the southeastern rainforest. Portuguese explorers reached the coast in the 15th century and named the area ''Rio dos Camarões'' (''Shrimp River''), which became ''Cameroon'' in English. Fulani soldiers founded the Adamawa Emirate ...
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Lusaka
Lusaka (; ) is the Capital city, capital and largest city of Zambia. It is one of the fastest-developing cities in southern Africa. Lusaka is in the southern part of the central plateau at an elevation of about . , the city's population was about 3.3 million, while the urban population is estimated at 2.5 million in 2018. Lusaka is the centre of both commerce and government in Zambia and connects to the country's four main highways heading Great North Road, Zambia, north, Livingstone Road, south, Great East Road, east and Great West Road, Zambia, west. English is the official language of the city administration, while Bemba language, Bemba, Tonga language (Zambia and Zimbabwe), Tonga, Lenje, Soli language, Soli, Lozi language, Lozi and Nyanja are the commonly spoken street languages. The earliest evidence of settlement in the area dates to the 6th century AD, with the first known settlement in the 11th century. It was then home to the Lenje people, Lenje and Soli language, Soli ...
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Zambia
Zambia (), officially the Republic of Zambia, is a landlocked country at the crossroads of Central Africa, Central, Southern Africa, Southern and East Africa, although it is typically referred to as being in Southern Africa at its most central point. Its neighbours are the Democratic Republic of the Congo to the north, Tanzania to the northeast, Malawi to the east, Mozambique to the southeast, Zimbabwe and Botswana to the south, Namibia to the southwest, and Angola to the west. The capital city of Zambia is Lusaka, located in the south-central part of Zambia. The nation's population of around 19.5 million is concentrated mainly around Lusaka in the south and the Copperbelt Province to the north, the core economic hubs of the country. Originally inhabited by Khoisan peoples, the region was affected by the Bantu expansion of the thirteenth century. Following the arrival of European exploration of Africa, European explorers in the eighteenth century, the British colonised the r ...
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Harare
Harare (; formerly Salisbury ) is the capital and most populous city of Zimbabwe. The city proper has an area of 940 km2 (371 mi2) and a population of 2.12 million in the 2012 census and an estimated 3.12 million in its metropolitan area in 2019. Situated in north-eastern Zimbabwe in the country's Mashonaland region, Harare is a metropolitan province, which also incorporates the municipalities of Chitungwiza and Epworth. The city sits on a plateau at an elevation of above sea level and its climate falls into the subtropical highland category. The city was founded in 1890 by the Pioneer Column, a small military force of the British South Africa Company, and named Fort Salisbury after the UK Prime Minister Lord Salisbury. Company administrators demarcated the city and ran it until Southern Rhodesia achieved responsible government in 1923. Salisbury was thereafter the seat of the Southern Rhodesian (later Rhodesian) government and, between 1953 and 1963, th ...
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Shona People
The Shona people () are part of the Bantu ethnic group native to Southern Africa, primarily living in Zimbabwe where they form the majority of the population, as well as Mozambique, South Africa, and a worldwide diaspora including global celebrities such as Thandiwe Newton. There are five major Shona language/dialect clusters : Karanga, Zezuru, Korekore, Manyika and Ndau. Regional classification The Shona people are grouped according to the dialect of the language they speak. Their estimated population is 16.6 million: * Karanga or Southern Shona (about 8.5 million people) * Zezuru or Central Shona (5.2 million people) * Korekore or Northern Shona (1.7 million people) * Manyika tribe or Eastern Shona (1.2 million) in Zimbabwe (861,000) and Mozambique (173,000). * Ndau in Mozambique (1,580,000) and Zimbabwe (800,000). History During the 11th century, the Karanga people formed kingdoms on the Zimbabwe plateau. Construction, then, began on Great Zimbabwe; the capital of t ...
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Zimbabwe
Zimbabwe (), officially the Republic of Zimbabwe, is a landlocked country located in Southeast Africa, between the Zambezi and Limpopo Rivers, bordered by South Africa to the south, Botswana to the south-west, Zambia to the north, and Mozambique to the east. The capital and largest city is Harare. The second largest city is Bulawayo. A country of roughly 15 million people, Zimbabwe has 16 official languages, with English, Shona language, Shona, and Northern Ndebele language, Ndebele the most common. Beginning in the 9th century, during its late Iron Age, the Bantu peoples, Bantu people (who would become the ethnic Shona people, Shona) built the city-state of Great Zimbabwe which became one of the major African trade centres by the 11th century, controlling the gold, ivory and copper trades with the Swahili coast, which were connected to Arab and Indian states. By the mid 15th century, the city-state had been abandoned. From there, the Kingdom of Zimbabwe was established, fol ...
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Uyghurs
The Uyghurs; ; ; ; zh, s=, t=, p=Wéiwú'ěr, IPA: ( ), alternatively spelled Uighurs, Uygurs or Uigurs, are a Turkic ethnic group originating from and culturally affiliated with the general region of Central and East Asia. The Uyghurs are recognized as native to the Xinjiang Uyghur Autonomous Region in Northwest China. They are one of China's 55 officially recognized ethnic minorities. The Uyghurs are recognized by the Chinese government as a regional minority and the titular people of Xinjiang. The Uyghurs have traditionally inhabited a series of oases scattered across the Taklamakan Desert within the Tarim Basin. These oases have historically existed as independent states or were controlled by many civilizations including China, the Mongols, the Tibetans and various Turkic polities. The Uyghurs gradually started to become Islamized in the 10th century and most Uyghurs identified as Muslims by the 16th century. Islam has since played an important role in Uyghur ...
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Bamileke People
The Bamileke are a Central African people who inhabit the Western High Plateau of Cameroon. Languages The Bamileke languages belong to the Grassfields branch of the Niger-Congo language family, which is sometimes labeled as a " Bantuoid language," rather than a Bantu language.Derek Nurse & Gérard Philippson, 2003, ''The Bantu Languages,'' p 227 History The Bamileke are said to have entered their current location from the Mbam region further north, They originally referred to themselves as ''Baliku''. ''Bamileke'' is thought to be a colonial corruption of their original names. They were later joined by the Tikar, Bali, Bamum and Bafia peoples, who migrated into their current region of Cameroon. This accounts for the use of the title ''Fon'' by all five of the ethnic groups. Like a king, the ''Fon'' is head of all authorities, from territory to civil and military, within a given kingdom. In the 17th century, the Bamileke migrated further south and west under the pressure of ...
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