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H5N8
H5 N8 is a subtype of the influenza A virus (sometimes called bird flu) and is highly lethal to wild birds and poultry. H5N8 is typically not associated with humans. However, seven people in Russia were found to be infected in 2021, becoming the first documented human cases. Virus and symptoms The H5N8 virus manifests itself in various ways, from asymptomatic and sub-clinical to highly lethal in some populations. Many of the findings in wild birds are based on the discovery of dead animals. Its intravenous pathogenicity index (IVPI) is greater than 1.2, giving it a mortality rate of at least 75 percent. H5N8 has previously been used in place of the highly pathogenic H1N1 in studies. Outbreaks 1983 Perhaps the most known outbreak of H5N8 occurred in Ireland in 1983. Poultry on two farms showed the usual symptoms, plus diarrhea, nervousness, and depression. Poultry farms within close proximity soon began to show signs of infection, as well, but no contact between the farms coul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza A Virus
''Influenza A virus'' (''IAV'') causes influenza in birds and some mammals, and is the only species of the genus ''Alphainfluenzavirus'' of the virus family ''Orthomyxoviridae''. Strain (biology)#Microbiology or virology, Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some primary isolate, isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics. Influenza A viruses are Sense (molecular biology), negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of Hemagglutinin (influenza), hemagglutinin) and an N number (for the type of viral neuraminidase, neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avian Influenza
Avian influenza, known informally as avian flu or bird flu, is a variety of influenza caused by viruses adapted to birds.Chapter Two : Avian Influenza by Timm C. Harder and Ortrud Werner in ''Influenza Report 2006'' CDC has a phylogenetic tree showing the relationship between dozens of highly pathogenic varieties of the Z genotype of avian flu virus H5N1 and ancestral strains. The type with the greatest risk is highly pathogenic avian influenza (HPAI). Bird flu is s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemagglutinin
In molecular biology, hemagglutinins (or ''haemagglutinin'' in British English) (from the Greek , 'blood' + Latin , 'glue') are receptor-binding membrane fusion glycoproteins produced by viruses in the ''Paramyxoviridae'' family. Hemagglutinins are responsible for binding to receptors on red blood cells to initiate viral attachment and infection. The agglutination of red cells occurs when antibodies on one cell bind to those on others, causing amorphous aggregates of clumped cells.Hemagglutinins recognize cell-surface glycoconjugates containing sialic acid on the surface of host red blood cells with a low affinity, and use them to enter the endosome of host cells. In the endosome, hemagglutinins are activated at a pH of 5 - 6.5, to undergo conformational changes that enable viral attachment through a fusion peptide. Agglutination and hemagglutinins were discovered by virologist George K. Hirst in 1941. Alfred Gottschalk proved in 1957 that hemagglutinins bind a virus to a host c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harare
Harare (; formerly Salisbury ) is the capital and most populous city of Zimbabwe. The city proper has an area of 940 km2 (371 mi2) and a population of 2.12 million in the 2012 census and an estimated 3.12 million in its metropolitan area in 2019. Situated in north-eastern Zimbabwe in the country's Mashonaland region, Harare is a metropolitan province, which also incorporates the municipalities of Chitungwiza and Epworth. The city sits on a plateau at an elevation of above sea level and its climate falls into the subtropical highland category. The city was founded in 1890 by the Pioneer Column, a small military force of the British South Africa Company, and named Fort Salisbury after the UK Prime Minister Lord Salisbury. Company administrators demarcated the city and ran it until Southern Rhodesia achieved responsible government in 1923. Salisbury was thereafter the seat of the Southern Rhodesian (later Rhodesian) government and, between 1953 and 1963, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gifu Prefecture
is a prefecture of Japan located in the Chūbu region of Honshu. Gifu Prefecture has a population of 1,991,390 () and has a geographic area of . Gifu Prefecture borders Toyama Prefecture to the north; Ishikawa Prefecture to the northwest, Fukui Prefecture and Shiga Prefecture to the west, Mie Prefecture to the southwest, Aichi Prefecture to the south, and Nagano Prefecture to the east. Gifu is the capital and largest city of Gifu Prefecture, with other major cities including Ōgaki, Kakamigahara, and Tajimi. Gifu Prefecture is located in the center of Japan, one of only eight landlocked prefectures, and features the country's center of population. Gifu Prefecture has served as the historic crossroads of Japan with routes connecting the east to the west, including the Nakasendō, one of the Five Routes of the Edo period. Gifu Prefecture was a long-term residence of Oda Nobunaga and Saitō Dōsan, two influential figures of Japanese history in the Sengoku period, spawning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Honshu
, historically called , is the largest and most populous island of Japan. It is located south of Hokkaidō across the Tsugaru Strait, north of Shikoku across the Inland Sea, and northeast of Kyūshū across the Kanmon Straits. The island separates the Sea of Japan, which lies to its north and west, from the North Pacific Ocean to the south and east. It is the seventh-largest island in the world, and the second-most populous after the Indonesian island of Java. Honshu had a population of 104 million , constituting 81.3% of the entire population of Japan, and is mostly concentrated in the coastal areas and plains. Approximately 30% of the total population resides in the Greater Tokyo Area on the Kantō Plain. As the historical center of Japanese cultural and political power, the island includes several past Japanese capitals, including Kyōto, Nara and Kamakura. Much of the island's southern shore forms part of the Taiheiyō Belt, a megalopolis that spans several of the Japane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kantō Region
The is a geographical area of Honshu, the largest island of Japan. In a common definition, the region includes the Greater Tokyo Area and encompasses seven prefectures: Gunma, Tochigi, Ibaraki, Saitama, Tokyo, Chiba and Kanagawa. Slightly more than 45 percent of the land area within its boundaries is the Kanto Plain. The rest consists of the hills and mountains that form land borders with other regions of Japan. As the Kanto region contains Tokyo, the capital and largest city of Japan, the region is considered the center of Japan's politics and economy. According to the official census on October 1, 2010, by the Japan Statistics Bureau, the population was 42,607,376, amounting to approximately one third of the total population of Japan. Other definitions The Kantō regional governors' association (関東地方知事会, ''Kantō chihō chijikai'') assembles the prefectural governors of Ibaraki, Tochigi, Gunma, Saitama, Chiba, Tokyo, Kanagawa, Yamanashi, Nagano and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kyushu Island
is the third-largest island of Japan's five main islands and the most southerly of the four largest islands ( i.e. excluding Okinawa). In the past, it has been known as , and . The historical regional name referred to Kyushu and its surrounding islands. Kyushu has a land area of and a population of 14,311,224 in 2018. In the 8th-century Taihō Code reforms, Dazaifu was established as a special administrative term for the region. Geography The island is mountainous, and Japan's most active volcano, Mount Aso at , is on Kyushu. There are many other signs of tectonic activity, including numerous areas of hot springs. The most famous of these are in Beppu, on the east shore, and around Mt. Aso in central Kyushu. The island is separated from Honshu by the Kanmon Straits. Being the nearest island to the Asian continent, historically it is the gateway to Japan. The total area is which makes it the 37th largest island in the world. It's slightly larger than Taiwan island . ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shikoku Island
is the smallest of the four main islands of Japan. It is long and between wide. It has a population of 3.8 million (, 3.1%). It is south of Honshu and northeast of Kyushu. Shikoku's ancient names include ''Iyo-no-futana-shima'' (), ''Iyo-shima'' (), and ''Futana-shima'' (), and its current name refers to the four former provinces that made up the island: Awa, Tosa, Sanuki, and Iyo. Geography Shikoku Island, comprising Shikoku and its surrounding islets, covers about and consists of four prefectures: Ehime, Kagawa, Kōchi, and Tokushima. Across the Seto Inland Sea lie Wakayama, Osaka, Hyōgo, Okayama, Hiroshima, and Yamaguchi Prefectures on Honshu. To the west lie Ōita and Miyazaki Prefectures on Kyushu. Shikoku is ranked as the 50th largest island by area in the world. Additionally, it is ranked as the 23rd most populated island in the world, with a population density of 193 inhabitants per square kilometre (500/sq mi). Mountains running east and west ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carola Schouten
Cornelia Johanna "Carola" Schouten (born 6 October 1977) is a Dutch politician serving as third Deputy Prime Minister of the Netherlands and Minister for Poverty Policy, Participation and Pensions in the IV Rutte Cabinet since 10 January 2022. She has served as Minister of Agriculture, Nature and Food Quality in the Third Rutte cabinet from 2017-2022. She is a member of the Christian Union (CU). Early life and education A native of 's-Hertogenbosch, Schouten grew up in Waardhuizen, managing her deceased father's dairy farm with her mother and her two sisters for four years, after which time the family ended the farming activities and moved to neighbouring village of Giessen (Waardhuizen and Giessen are nowadays located in the new municipality of Altena). She attended Altena College in Sleeuwijk and studied business administration at Erasmus University Rotterdam with a year abroad at Tel Aviv University. Schouten worked at the Ministry of Social Affairs and Employment from 200 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mpumalanga
Mpumalanga () is a province of South Africa. The name means "East", or literally "The Place Where the Sun Rises" in the Swazi, Xhosa, Ndebele and Zulu languages. Mpumalanga lies in eastern South Africa, bordering Eswatini and Mozambique. It constitutes 6.5% of South Africa's land area. It shares borders with the South African provinces of Limpopo to the north, Gauteng to the west, the Free State to the southwest, and KwaZulu-Natal to the south. The capital is Mbombela. Mpumalanga was formed in 1994, when the area that was the Eastern Transvaal was merged with the former bantustans KaNgwane, KwaNdebele and parts of Lebowa and Gazankulu. Although the contemporary borders of the province were only formed at the end of apartheid, the region and its surroundings has a history that extends back thousands of years. Much of its history, and current significance is as a region of trade. History Precolonial Era Archeological sites in the Mpumalanga region indicate settlement b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
