Hutan Ashrafian
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Hutan Ashrafian
Hutan Ashrafian is an academic, cardiothoracic surgeon, robotic surgeon, bariatric surgeon, computational biologist, immunologist, entrepreneur, historian, writer, martial artist and philosopher. He is the current chief scientific officer of Preemptive Health and Medicine at Flagship Pioneering. Ashrafian thoracotomy, surgical procedure, and the Ashrafian sign aortic regurgitation are named after him. He introduced the AIonAI law for artificial intelligence. Early life and education Ashrafian attended the Westminster School and then University College London, where he completed Bachelor of Science in immunology and cell pathology and subsequently a medical degree (MD) in 2000. Following London-based surgical training in pediatric cardiothoracic surgery, robotic surgery , general surgery with specialist training in bariatric surgery, in 2015, he finished his Wellcome Trust PhD in computational biology and surgery from Imperial College London and was appointed National ...
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Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ...
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Leeds University Business School
Leeds University Business School is a business school in the University of Leeds, in Leeds, West Yorkshire, England. The school is accredited by AACSB, AMBA and EQUIS. Location Leeds University Business School is housed in several buildings at the University of Leeds, including the 19th-century Maurice Keyworth building (previously Leeds Grammar School), Charles Thackrah building and Clarendon building. The School also shares the Newlyn building and Esther Simpson building with the School of Law, which officially opened in October 2019 and March 2022 respectively. Leeds University Business School is situated on the western campus of the University of Leeds, located north of Leeds city centre. The Marks & Spencer company archive is also housed here, containing over 60,000 artefacts and pieces moved there in 2009 from London to Leeds, the birthplace of the company. Further buildings include the Liberty Building, home to the Faculty of Law, and Western Lecture Theatre. Profil ...
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COVID-19 Vaccine
A COVID19 vaccine is a vaccine intended to provide acquired immunity against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2), the virus that causes coronavirus disease 2019 ( COVID19). Prior to the COVID19 pandemic, an established body of knowledge existed about the structure and function of coronaviruses causing diseases like severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). This knowledge accelerated the development of various vaccine platforms during early 2020. The initial focus of SARS-CoV-2 vaccines was on preventing symptomatic, often severe illness. In January 2020, the SARS-CoV-2 genetic sequence data was shared through GISAID, and by March 2020, the global pharmaceutical industry announced a major commitment to address COVID19. In 2020, the first COVID19 vaccines were developed and made available to the public through emergency authorizations and conditional approvals. Initially, most COVID19 vaccines were two ...
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Chief Medical Officer
Chief medical officer (CMO) is the title used in many countries for the senior government official designated head of medical services, sometimes at the national level. The post is held by a physician who serves to advise and lead a team of medical experts on matters of public health importance. The post of chief medical officer dates back to Victorian times. The equivalent title may go under different names across countries, for example, the Surgeon General in the United States and the Chief Public Health Officer in Canada. By extension, chief medical officer is also used as a job title, for the physician who is the professional lead of all physicians at a hospital. See also * Chief Medical Officer (Australia) * Chief Medical Officer (Ireland) * Chief Medical Officers (United Kingdom) * Chief of staff The title chief of staff (or head of staff) identifies the leader of a complex organization such as the armed forces, institution, or body of persons and it also may identify a ...
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COVID-19
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December 2019. The disease quickly spread worldwide, resulting in the COVID-19 pandemic. The symptoms of COVID‑19 are variable but often include fever, cough, headache, fatigue, breathing difficulties, Anosmia, loss of smell, and Ageusia, loss of taste. Symptoms may begin one to fourteen days incubation period, after exposure to the virus. At least a third of people who are infected Asymptomatic, do not develop noticeable symptoms. Of those who develop symptoms noticeable enough to be classified as patients, most (81%) develop mild to moderate symptoms (up to mild pneumonia), while 14% develop severe symptoms (dyspnea, Hypoxia (medical), hypoxia, or more than 50% lung involvement on imaging), and 5% develop critical symptoms (respiratory failure ...
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Institute Of Global Health Innovation
The Institute of Global Health Innovation is one of Imperial College London’s global challenge Institutes. Established in 2010, its mission is to improve global health and care through evidence-based innovation. The Institute’s work aims to support the identification, development and implementation of healthcare innovation, with the goal of sustainably reducing inequalities in global health. The Institute is cross-disciplinary and works across a range of fields including data science, mathematics, health economics, medicine, policy, design and engineering. Its focus is on translational research. In addition to research and development, the Institute offers a number of educational and training programmes, and hosts regular events. It also works to influence health policy through evidence generation and dissemination. Research The Institute works across a broad range of global healthcare issues, including COVID-19, mental health, patient safety, nutrition, digital health, end o ...
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Master Of Business Administration
A Master of Business Administration (MBA; also Master's in Business Administration) is a postgraduate degree focused on business administration. The core courses in an MBA program cover various areas of business administration such as accounting, applied statistics, human resources, business communication, business ethics, business law, strategic management, business strategy, finance, managerial economics, management, entrepreneurship, marketing, supply-chain management, and operations management in a manner most relevant to management analysis and strategy. It originated in the United States in the early 20th century when the country industrialized and companies sought scientific management. Some programs also include elective courses and concentrations for further study in a particular area, for example, accounting, finance, marketing, and human resources, but an MBA is intended to be a generalized program. MBA programs in the United States typically require completing ...
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National Institute For Health And Care Research
The National Institute for Health and Care Research (NIHR) is the British government’s major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "improve the health and wealth of the nation through research". The NIHR was established in 2006 under the government's Best Research for Best Health strategy, and is funded by the Department of Health and Social Care. As a research funder and research partner of the NHS, public health and social care, the NIHR complements the work of the Medical Research Council. NIHR focuses on translational research (translating discoveries from the laboratory to the clinic), clinical research and applied health and social care research. History The NIHR (originally named National Institute for Health Research) was created in April 2006 under the government's health research strategy, Best Research for Best Health. This strategy outlined the direction that ...
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Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting ...
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Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of GlaxoSmithKline) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of Pound sterling, £29.1 billion in 2020, making it the fourth List of wealthiest charitable foundations, wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the ''Financial Times'' as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of the largest providers in the world. According to their annual report, the Wellcome Trust spent GBP Pound sterling, £1.1Bn on charitable activities across their 2019/2020 financial year. According to the OECD, the Wellcome ...
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Bariatric Surgery
Bariatric surgery (or weight loss surgery) includes a variety of procedures performed on people who are obese. Long term weight loss through the standard of care procedures ( Roux en-Y bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch) is largely achieved by altering gut hormone levels responsible for hunger and satiety, leading to a new hormonal weight set point. Bariatric surgery is the most effective treatment causing weight loss and reducing complications of obesity. As of October 2022, the American Society of Metabolic and Bariatric Surgery (ASMBS) and International Federation for the Surgery of Obesity (IFSO) recommend bariatric surgery for adults with a body mass index (BMI) >35, regardless of obesity-associated conditions, and recommend considering surgery for people with BMI 30.0-34.9 who have metabolic disease. This is a recent change in guidelines (October 2022), so other guideline-producing organizations and health insurance plans may t ...
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