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Howard Florey Institute
The Florey Institute of Neuroscience and Mental Health, more commonly known as the Florey Institute, is an Australian medical research institute that undertakes clinical and applied research into treatments for brain and mind disorders and the cardiovascular system. The institute's areas of interest include Parkinson's disease, stroke, motor neurone disease, traumatic brain and spinal cord injury, addiction, epilepsy, multiple sclerosis, brain development in premature babies, Autism, Huntington's disease, depression, schizophrenia, brain function in health and disease, heart failure, and dementia. Affiliated with the University of Melbourne and the Austin Hospital, the institute is located in the Melbourne suburbs of and in Victoria. It is the largest brain research group in the southern hemisphere and employs approximately 600 staff and students. The institute is led by its director, Professor Steven Petrou, who specialises in the underlying electrophysiological basis of gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harold Mitchell (media Buyer)
Harold Charles Mitchell (born 13 May 1942) is an Australian entrepreneur, media buyer, philanthropist and humanitarian. Life Harold Mitchell was born in Trafalgar, Victoria, one of four children. His father was a sawmiller who had to go wherever the work was. His mother left the marriage when he was 15. By the time Harold was 16, the single-parent family was living in Stawell, Victoria. He left school early and worked in the local sawmill for some months and then went to work for an advertising agency in Melbourne, a city he had only ever visited once. He studied part-time at RMIT. He became a successful media buyer, founded his own company, and led the development of the media buying industry in Australia. He is the Executive Chairman of the Mitchell Communication Group and Executive Chairman, Aegis Media Pacific, part of the Aegis Group. He is also involved in Television Sydney. In 2000, he created the Harold Mitchell Foundation, which donates money to various causes promo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multiple Sclerosis
Multiple (cerebral) sclerosis (MS), also known as encephalomyelitis disseminata or disseminated sclerosis, is the most common demyelinating disease, in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems. Specific symptoms can include double vision, blindness in one eye, muscle weakness, and trouble with sensation or coordination. MS takes several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms). In the relapsing forms of MS, between attacks, symptoms may disappear completely, although some permanent neurological problems often remain, especially as the disease advances. While the cause is unclear, the underlying mechanism is thought to be either destruction by the immune system ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aldosterone
Aldosterone is the main mineralocorticoid steroid hormone produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. It is essential for sodium conservation in the kidney, salivary glands, sweat glands, and colon. It plays a central role in the homeostatic regulation of blood pressure, plasma sodium (Na+), and potassium (K+) levels. It does so primarily by acting on the mineralocorticoid receptors in the distal tubules and collecting ducts of the nephron. It influences the reabsorption of sodium and excretion of potassium (from and into the tubular fluids, respectively) of the kidney, thereby indirectly influencing water retention or loss, blood pressure, and blood volume.Marieb Human Anatomy & Physiology 9th edition, chapter:16, page:629, question number:14 When dysregulated, aldosterone is pathogenic and contributes to the development and progression of cardiovascular and kidney disease. Aldosterone has exactly the opposite function of the atrial natriure ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone
A hormone (from the Greek participle , "setting in motion") is a class of signaling molecules in multicellular organisms that are sent to distant organs by complex biological processes to regulate physiology and behavior. Hormones are required for the correct development of animals, plants and fungi. Due to the broad definition of a hormone (as a signaling molecule that exerts its effects far from its site of production), numerous kinds of molecules can be classified as hormones. Among the substances that can be considered hormones, are eicosanoids (e.g. prostaglandins and thromboxanes), steroids (e.g. oestrogen and brassinosteroid), amino acid derivatives (e.g. epinephrine and auxin), protein or peptides (e.g. insulin and CLE peptides), and gases (e.g. ethylene and nitric oxide). Hormones are used to communicate between organs and tissues. In vertebrates, hormones are responsible for regulating a variety of physiological processes and behavioral activities such as diges ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electrolyte
An electrolyte is a medium containing ions that is electrically conducting through the movement of those ions, but not conducting electrons. This includes most soluble salts, acids, and bases dissolved in a polar solvent, such as water. Upon dissolving, the substance separates into cations and anions, which disperse uniformly throughout the solvent. Solid-state electrolytes also exist. In medicine and sometimes in chemistry, the term electrolyte refers to the substance that is dissolved. Electrically, such a solution is neutral. If an electric potential is applied to such a solution, the cations of the solution are drawn to the electrode that has an abundance of electrons, while the anions are drawn to the electrode that has a deficit of electrons. The movement of anions and cations in opposite directions within the solution amounts to a current. Some gases, such as hydrogen chloride (HCl), under conditions of high temperature or low pressure can also function as electrolytes. El ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nobel Prize In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine is awarded yearly by the Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single prize, but five separate prizes that, according to Alfred Nobel's 1895 will, are awarded "to those who, during the preceding year, have conferred the greatest benefit to humankind". Nobel Prizes are awarded in the fields of Physics, Chemistry, Physiology or Medicine, Literature, and Peace. The Nobel Prize is presented annually on the anniversary of Alfred Nobel's death, 10 December. As of 2022, 114 Nobel Prizes in Physiology or Medicine have been awarded to 226 laureates, 214 men and 12 women. The first one was awarded in 1901 to the German physiologist, Emil von Behring, for his work on serum therapy and the development of a vaccine against diphtheria. The first woman to receive the Nobel Prize in Physiology or Medicine, Gerty Cori, received it in 1947 for her role in elucidati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Nobel Laureates In Physiology Or Medicine
The Nobel Prize in Physiology or Medicine ( sv, Nobelpriset i fysiologi eller medicin) is awarded annually by the Swedish Karolinska Institutet, Karolinska Institute to scientists in the various fields of physiology or medicine. It is one of the five Nobel Prizes established by the 1895 will (law), will of Alfred Nobel (who died in 1896), awarded for outstanding contributions in Nobel Prize in Chemistry, chemistry, Nobel Prize in Physics, physics, Nobel Prize in Literature, literature, Nobel Peace Prize, peace, and physiology or medicine. As dictated by Nobel's will, the award is administered by the Nobel Foundation and awarded by a committee that consists of five members and an executive secretary elected by the Karolinska Institute. While commonly referred to as the Nobel Prize in Medicine, Nobel specifically stated that the prize be awarded for "physiology or medicine" in his will. Because of this, the prize can be awarded in a broader range of fields. The first Nobel Prize in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Howard Florey
Howard Walter Florey, Baron Florey (24 September 189821 February 1968) was an Australian pharmacologist and pathologist who shared the Nobel Prize in Physiology or Medicine in 1945 with Sir Ernst Chain and Sir Alexander Fleming for his role in the development of penicillin. Although Fleming received most of the credit for the discovery of penicillin, it was Florey who carried out the first clinical trials of penicillin in 1941 at the Radcliffe Infirmary in Oxford on the first patient, a police constable from Oxford. The patient started to recover, but subsequently died because Florey was unable, at that time, to make enough penicillin. It was Florey and Chain who actually made a useful and effective drug out of penicillin, after the task had been abandoned as too difficult. Florey's discoveries, along with the discoveries of Fleming and Ernst Chain, are estimated to have saved over 200 million lives, and he is consequently regarded by the Australian scientific and medical comm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Government Of Victoria
The Victoria State Government, also referred to as just the Victorian Government, is the state-level authority for Victoria (Australia), Victoria, Australia. Like all state governments, it is formed by three independent branches: the executive, the Supreme Court of Victoria, judicial, and the Parliament of Victoria, parliament. As a parliamentary system, parliamentary constitutional monarchy, the State Government was first formed in 1851 when Victoria first gained the right to responsible government. The Constitution of Australia regulates the relationship between the Victorian Government and the Australian Government, and cedes legislative and judicial supremacy to the federal government on conflicting matters. The Victoria State Government enforces Act of Parliament, acts passed by the parliament through government departments, statutory authorities, and other public agencies. The Government is formally presided over by the Governor of Victoria, Governor, who exercises execu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Derek Denton
Derek Ashworth Denton (27 May 1924 – 18 November 2022) was an Australian scientist who elucidated the regulation of electrolytes in extracellular fluid, the hormones controlling this regulation, particularly aldosterone, and the instinctive behaviours controlling intake of water and salts. He was cited in 1995 at election to the U.S. National Academy of Sciences as the world’s leading authority on the regulation of salt and water metabolism and relevant endocrine control mechanisms. He was one of Australia’s most eminent scientists. Career Denton was the founding Director and Emeritus Director of the Howard Florey Institute, Honorary Professor at the University of Melbourne, and a consultant at the Baker Research Institute. Denton's last book is ''The Primordial Emotions, The Primordial Emotions: The Dawning of Consciousness''. Research Three months after medical graduation in 1947, he made a basic discovery on kidney function at the Royal Melbourne Hospital. In the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dementia
Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affects a person's ability to function and carry out everyday activities. Aside from memory impairment and a disruption in thought patterns, the most common symptoms include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum over several stages. Consciousness is not affected. Dementia ultimately has a significant effect on the individual, caregivers, and on social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning, and a greater cognitive decline than what is caused by normal aging. Several diseases and injuries to the brain, such as a stroke, can give rise to dementia. However, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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