Honey Bee Genome Sequencing Consortium
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Honey Bee Genome Sequencing Consortium
The Honey Bee Genome Sequencing Consortium is an international collaborative group of genomics scientists, scientific organisations and universities trying to decipher the genome sequences of the honey bee (''Apis mellifera''). It was formed in 2001 by American scientists. In the US, the project is funded by the National Human Genome Research Institute (a division of the National Institutes of Health (NIH)), the United States Department of Agriculture (USDA), the Texas Agricultural Experiment Station, the University of Illinois Sociogenomics Initiative, and various beekeepers association and the bee industry. First scientific findings show that the honey bee genome may have evolved more slowly than the genomes of the fruit fly and malaria mosquito. The bee genome contains versions of some important mammalian genes. The complete genome of ''Apis mellifera'' has been sequenced and consists of 10,000 genes with approximately 236 million base pairs. The size of the genome is a ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Base Pair
A base pair (bp) is a fundamental unit of double-stranded nucleic acids consisting of two nucleobases bound to each other by hydrogen bonds. They form the building blocks of the DNA double helix and contribute to the folded structure of both DNA and RNA. Dictated by specific hydrogen bonding patterns, "Watson–Crick" (or "Watson–Crick–Franklin") base pairs (guanine–cytosine and adenine–thymine) allow the DNA helix to maintain a regular helical structure that is subtly dependent on its nucleotide sequence. The Complementarity (molecular biology), complementary nature of this based-paired structure provides a redundant copy of the genetic information encoded within each strand of DNA. The regular structure and data redundancy provided by the DNA double helix make DNA well suited to the storage of genetic information, while base-pairing between DNA and incoming nucleotides provides the mechanism through which DNA polymerase replicates DNA and RNA polymerase transcribes DNA in ...
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Genome Projects
Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism (be it an animal, a plant, a fungus, a bacterium, an archaean, a protist or a virus) and to annotate protein-coding genes and other important genome-encoded features. The genome sequence of an organism includes the collective DNA sequences of each chromosome in the organism. For a bacterium containing a single chromosome, a genome project will aim to map the sequence of that chromosome. For the human species, whose genome includes 22 pairs of autosomes and 2 sex chromosomes, a complete genome sequence will involve 46 separate chromosome sequences. The Human Genome Project is a well known example of a genome project. Genome assembly Genome assembly refers to the process of taking a large number of short DNA sequences and reassembling them to create a representation of the original chromosomes from which the DNA originated. In a shotgun sequencing project, all th ...
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Genomics
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ...
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Beekeeping Organizations
Beekeeping (or apiculture) is the maintenance of bee colonies, commonly in man-made beehives. Honey bees in the genus '' Apis'' are the most-commonly-kept species but other honey-producing bees such as ''Melipona'' stingless bees are also kept. Beekeepers (or apiarists) keep bees to collect honey and other products of the hive: beeswax, propolis, bee pollen, and royal jelly. Pollination of crops, raising queens, and production of package bees for sale are other sources of beekeeping income. Bee hives are kept in an apiary or "bee yard". The keeping of bees by humans, primarily for honey production, began around 10,000 years ago. Georgia is known as the "cradle of beekeeping" and the oldest honey ever found comes from that country. The 5,500-year-old honey was unearthed from the grave of a noblewoman during archaeological excavations in 2003 near the town Borjomi. Ceramic jars found in the grave contained several types of honey, including linden and flower honey. Domestication of ...
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List Of Sequenced Eukaryotic Genomes
This list of "sequenced" eukaryotic genomes contains all the eukaryotes known to have publicly available complete nuclear and organelle genome sequences that have been sequenced, assembled, annotated and published; draft genomes are not included, nor are organelle-only sequences. DNA was first sequenced in 1977. The first free-living organism to have its genome completely sequenced was the bacterium ''Haemophilus influenzae'', in 1995. In 1996 ''Saccharomyces cerevisiae'' (baker's yeast) was the first eukaryote genome sequence to be released and in 1998 the first genome sequence for a multicellular eukaryote, '' Caenorhabditis elegans'', was released. Protists Following are the nine earliest sequenced genomes of protists. For a more complete list, see the List of sequenced protist genomes. Plants Following are the five earliest sequenced genomes of plants. For a more complete list, see the List of sequenced plant genomes. Fungi Following are the five earliest sequenced gen ...
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Texas A&M University
Texas A&M University (Texas A&M, A&M, or TAMU) is a public, land-grant, research university in College Station, Texas. It was founded in 1876 and became the flagship institution of the Texas A&M University System in 1948. As of late 2021, Texas A&M has the largest student body in the United States, and is the only university in Texas to hold simultaneous designations as a land, sea, and space grant institution. In 2001, it was inducted into the Association of American Universities. The university's students, alumni, and sports teams are known as Aggies, and its athletes compete in eighteen varsity sports as a member of the Southeastern Conference. The university was the first public higher-education institution in Texas; it opened for classes on October 4, 1876, as the Agricultural and Mechanical College of Texas (A.M.C.) under the provisions of the 1862 Morrill Land-Grant Act. In the following decades, the college grew in size and scope, expanding to its largest enrol ...
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Beebase
BeeBase is an online bioinformatics database that displays data related to ''Apis mellifera'', the European honey bee along with some pathogens and other species. It was developed in collaboration with the Honey Bee Genome Sequencing Consortium.BeeBase website - http://hymenopteragenome.org/beebase/ In 2020 it was archived and replaced by the Hymenoptera Genome Database. Data The site hosts the genome sequence for ''apis mellifera'' along with those of the following pathogens: * ''Bombus terrestris'' * ''Bombus impatiens'' Two additional species are under analysis: * ''Apis dorsata'' * ''Apis florea'' In Feb 2007, ''BeeBase'' consisted of a GBrowser-based genome viewer and a CMap-based] comparative map viewer, both modules of the Generic Model Organism Database (GMOD) project. The genome viewer included tracks for known honey bee genes, predicted gene sets (Ensembl, NCBI, EMBL-Heidelberg), STS markers (Solignac and Hunt linkage maps), honey bee expressed sequence tags (ESTs) ...
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Cuticula
A cuticle (), or cuticula, is any of a variety of tough but flexible, non-mineral outer coverings of an organism, or parts of an organism, that provide protection. Various types of "cuticle" are non- homologous, differing in their origin, structure, function, and chemical composition. Human anatomy In human anatomy, "cuticle" can refer to several structures, but it is used in general parlance, and even by medical professionals, to refer to the thickened layer of skin surrounding fingernails and toenails (the eponychium), and to refer to the superficial layer of overlapping cells covering the hair shaft ( cuticula pili), consisting of dead cells, that locks the hair into its follicle. It can also be used as a synonym for the epidermis, the outer layer of skin. Cuticle of invertebrates In zoology, the invertebrate cuticle or cuticula is a multi-layered structure outside the epidermis of many invertebrates, notably roundworms and arthropods, in which it forms an exoskeleton ( ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ...
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Mammalian Gene
Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles (including birds) from which they diverged in the Carboniferous, over 300 million years ago. Around 6,400 extant species of mammals have been described divided into 29 orders. The largest orders, in terms of number of species, are the rodents, bats, and Eulipotyphla (hedgehogs, moles, shrews, and others). The next three are the Primates (including humans, apes, monkeys, and others), the Artiodactyla (cetaceans and even-toed ungulates), and the Carnivora (cats, dogs, seals, and others). In terms of cladistics, which reflects evolutionary history, mammals are the only living members of the Synapsida (synapsids); this clade, together with Sauropsida ...
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