History Of Diabetes
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History Of Diabetes
The condition known today as diabetes (usually referring to ''diabetes mellitus'') is thought to have been described in the Ebers Papyrus (). Ayurvedic physicians (5th/6th century BC) first noted the sweet taste of diabetic urine, and called the condition ''madhumeha'' ("honey urine"). The term ''diabetes'' traces back to Demetrius of Apamea (1st century BC). For a long time, the condition was described and treated in traditional Chinese medicine ''as'' (; "wasting-thirst"). Physicians of the medieval Islamic world, including Avicenna, have also written on diabetes. Early accounts often referred to diabetes as a disease of the kidneys. In 1674, Thomas Willis suggested that diabetes may be a disease of the blood. Johann Peter Frank is credited with distinguishing diabetes mellitus and diabetes insipidus in 1794. In regard to ''diabetes mellitus'', Joseph von Mering and Oskar Minkowski are commonly credited with the formal discovery (1889) of a role for the pancreas in causi ...
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Diabetes
Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased appetite. If left untreated, diabetes can cause many health complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or death. Serious long-term complications include cardiovascular disease, stroke, chronic kidney disease, foot ulcers, damage to the nerves, damage to the eyes, and cognitive impairment. Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding properly to the insulin produced. Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy. There are three main types of diabetes mellitus: * Type 1 diabetes results from failure of the pancreas to produce enough insulin due to lo ...
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Frederick Banting
Sir Frederick Grant Banting (November 14, 1891 – February 21, 1941) was a Canadian medical scientist, physician, painter, and Nobel laureate noted as the co-discoverer of insulin and its therapeutic potential. In 1923, Banting and John Macleod received the Nobel Prize in Medicine. Banting shared the honours and award money with his colleague, Charles Best. That same year, the government of Canada granted Banting a lifetime annuity to continue his work. As to this day, Frederick Banting, who received the Nobel Prize at age 32, remains the youngest Nobel laureate for Physiology/Medicine. Early years Frederick Banting was born on November 14, 1891, in a farmhouse near Alliston, Ontario. The youngest of five children of William Thompson Banting and Margaret Grant, he attended public high school in Alliston. In 1910, he started at Victoria College, part of the University of Toronto, in the General Arts program. After failing his first year, he petitioned to join the m ...
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Georg Ebers
Georg Moritz Ebers (Berlin, 1 March 1837 – Tutzing, Bavaria, 7 August 1898) was a German Egyptologist and novelist. He is best known for his purchase of the Ebers Papyrus, one of the oldest Egyptian medical documents in the world. Life Georg Ebers was born in Berlin and was the youngest of the five children of an affluent family of bankers and porcelain manufacturers. The Ebers children were raised by their mother on her own, after their father committed suicide shortly after Ebers was born. His mother ran a salon popular among members of the intelligentsia, which included Georg Wilhelm Friedrich Hegel, the Grimm Brothers, and Alexander von Humboldt. At Göttingen, Ebers studied jurisprudence, and at Berlin Oriental languages and archaeology. Having made a special study of Egyptology, he became in 1865 ''Dozent'' in Egyptian language and antiquities at Jena, becoming professor in 1868. In 1870 he was appointed professor in these subjects at Leipzig. He had made two scientif ...
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First Dynasty Of Egypt
The First Dynasty of ancient Egypt (Dynasty I) covers the first series of Egyptian kings to rule over a unified Egypt. It immediately follows the unification of Upper and Lower Egypt, possibly by Narmer, and marks the beginning of the Early Dynastic Period, a time at which power was centered at Thinis. The date of this period is subject to scholarly debate about the Egyptian chronology. It falls within the early Bronze Age and is variously estimated to have begun anywhere between the 34th and the 30th centuriesBC. In a 2013 study based on radiocarbon dates, the beginning of the First Dynasty—the accession of Narmer (commonly known as Menes)—was placed at 3100BC give or take a century (3218–3035, with 95% confidence). The dynasty Information about this dynasty is derived from a few monuments and other objects bearing royal names, the most important being the Narmer Palette and Narmer Macehead, as well as Den and Qa'a king lists. No detailed records of the first two dynas ...
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Papyrus
Papyrus ( ) is a material similar to thick paper that was used in ancient times as a writing surface. It was made from the pith of the papyrus plant, '' Cyperus papyrus'', a wetland sedge. ''Papyrus'' (plural: ''papyri'') can also refer to a document written on sheets of such material, joined side by side and rolled up into a scroll, an early form of a book. Papyrus is first known to have been used in Egypt (at least as far back as the First Dynasty), as the papyrus plant was once abundant across the Nile Delta. It was also used throughout the Mediterranean region. Apart from a writing material, ancient Egyptians employed papyrus in the construction of other artifacts, such as reed boats, mats, rope, sandals, and baskets. History Papyrus was first manufactured in Egypt as far back as the fourth millennium BCE.H. Idris Bell and T.C. Skeat, 1935"Papyrus and its uses"(British Museum pamphlet). The earliest archaeological evidence of papyrus was excavated in 2012 and 2 ...
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Berta Scharrer
Berta Vogel Scharrer (December 1, 1906 – July 23, 1995) was an American scientist who helped to found the scientific discipline now known as neuroendocrinology. Career Berta Vogel was born in Munich, Germany to Karl Phillip Vogel and Johanna Weiss. Her father served as vice-president of the federal court of Bavaria. She received her Ph.D. from the University of Munich. She worked at the university with Professor Karl von Frisch, who shared the Nobel Prize in Physiology or Medicine in 1973 for his work with bees. Berta Scharrer was forced to emigrate at the onset of the Holocaust. She arrived with her husband, Ernst Scharrer, in the United States with a total of eight dollars. Despite discrimination against women scientists at the time, she eventually got a professorship at the Albert Einstein College of Medicine, the medical school of Yeshiva University, in September 1955. Scharrer also contributed to the field of neuroimmunology, and in the six years prior to her death, publish ...
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Hypothalamus
The hypothalamus () is a part of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland. The hypothalamus is located below the thalamus and is part of the limbic system. In the terminology of neuroanatomy, it forms the ventral part of the diencephalon. All vertebrate brains contain a hypothalamus. In humans, it is the size of an almond. The hypothalamus is responsible for regulating certain metabolic processes and other activities of the autonomic nervous system. It synthesizes and secretes certain neurohormones, called releasing hormones or hypothalamic hormones, and these in turn stimulate or inhibit the secretion of hormones from the pituitary gland. The hypothalamus controls body temperature, hunger, important aspects of parenting and maternal attachment behaviours, thirst, fatigue, sleep, and circadian rhythms. Structure T ...
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Pituitary Gland
In vertebrate anatomy, the pituitary gland, or hypophysis, is an endocrine gland, about the size of a chickpea and weighing, on average, in humans. It is a protrusion off the bottom of the hypothalamus at the base of the brain. The hypophysis rests upon the hypophyseal fossa of the sphenoid bone in the center of the middle cranial fossa and is surrounded by a small bony cavity (sella turcica) covered by a dural fold (diaphragma sellae). The anterior pituitary (or adenohypophysis) is a lobe of the gland that regulates several physiological processes including stress, growth, reproduction, and lactation. The intermediate lobe synthesizes and secretes melanocyte-stimulating hormone. The posterior pituitary (or neurohypophysis) is a lobe of the gland that is functionally connected to the hypothalamus by the median eminence via a small tube called the pituitary stalk (also called the infundibular stalk or the infundibulum). Hormones secreted from the pituitary gland ...
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Antidiuretic
An antidiuretic is a substance that helps to control fluid balance in an animal's body by reducing urination, opposing diuresis. Its effects are opposite that of a diuretic. The major endogenous antidiuretics are antidiuretic hormone (ADH; also called vasopressin) and oxytocin. Both of those are also used exogenously as medications in people whose bodies need extra help with fluid balance via suppression of diuresis. In addition, there are various other antidiuretic drugs, some molecularly close to ADH or oxytocin and others not. Antidiuretics reduce urine volume, particularly in diabetes insipidus (DI), which is one of their main indications. The antidiuretic hormone class includes vasopressin (ADH), argipressin, desmopressin, lypressin, ornipressin, oxytocin, and terlipressin. Miscellaneous others include chlorpropamide and carbamazepine. See also *Diuretic *Electrolyte *Water-electrolyte imbalance Electrolyte imbalance, or water-electrolyte imbalance, is an abnormality in ...
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University Of Toronto
The University of Toronto (UToronto or U of T) is a public research university in Toronto, Ontario, Canada, located on the grounds that surround Queen's Park. It was founded by royal charter in 1827 as King's College, the first institution of higher learning in Upper Canada. Originally controlled by the Church of England, the university assumed its present name in 1850 upon becoming a secular institution. As a collegiate university, it comprises eleven colleges each with substantial autonomy on financial and institutional affairs and significant differences in character and history. The university maintains three campuses, the oldest of which, St. George, is located in downtown Toronto. The other two satellite campuses are located in Scarborough and Mississauga. The University of Toronto offers over 700 undergraduate and 200 graduate programs. In all major rankings, the university consistently ranks in the top ten public universities in the world and as the top university ...
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