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History Of Virology
The history of virology – the scientific study of viruses and the infections they cause – began in the closing years of the 19th century. Although Louis Pasteur and Edward Jenner developed the first vaccines to protect against viral infections, they did not know that viruses existed. The first evidence of the existence of viruses came from experiments with filters that had pores small enough to retain bacteria. In 1892, Dmitri Ivanovsky used one of these filters to show that sap from a diseased tobacco plant remained infectious to healthy tobacco plants despite having been filtered. Martinus Beijerinck called the filtered, infectious substance a "virus" and this discovery is considered to be the beginning of virology. The subsequent discovery and partial characterization of bacteriophages by Frederick Twort and Félix d'Herelle further catalyzed the field, and by the early 20th century many viruses had been discovered. In 1926, Thomas Milton Rivers defined viruses as obligat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ivanovsky
Ivanovsky (russian: Ивановский; masculine), Ivanovskaya (; feminine), or Ivanovskoye (; neuter), are forms of a Russian adjective derived from the first name Ivan. It may refer to: People * Ivanovsky (surname) (feminine: Ivanovskaya), Russian surname Places * Ivanovsky District, name of several districts in Russia * Ivanovsky Municipal Okrug, a municipal okrug of Nevsky District of St. Petersburg, Russia * Ivanovsky (rural locality) (Ivanovskaya, Ivanovskoye), name of several rural localities in Russia * Ivanovo Oblast (), a federal subject of Russia * Ivanovskoye District, a district of Eastern Administrative Okrug, Moscow, Russia *Ivanovsky Waterfall The Ivanovsky (Ивановский) is a 10-metre high waterfall in the Sochi National Park, Russia. It is part of the Psakho River. Just below the waterfall is a small cool lake. In summertime, the waterfall is frequented by tourists. Other S ..., a waterfall in Sochi National Park, Russia See also * Ivanovski< ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul Frosch
Paul may refer to: *Paul (given name), a given name (includes a list of people with that name) *Paul (surname), a list of people People Christianity * Paul the Apostle (AD c.5–c.64/65), also known as Saul of Tarsus or Saint Paul, early Christian missionary and writer *Pope Paul (other), multiple Popes of the Roman Catholic Church *Saint Paul (other), multiple other people and locations named "Saint Paul" Roman and Byzantine empire *Lucius Aemilius Paullus Macedonicus (c. 229 BC – 160 BC), Roman general *Julius Paulus Prudentissimus (), Roman jurist *Paulus Catena (died 362), Roman notary *Paulus Alexandrinus (4th century), Hellenistic astrologer *Paul of Aegina or Paulus Aegineta (625–690), Greek surgeon Royals * Paul I of Russia (1754–1801), Tsar of Russia *Paul of Greece (1901–1964), King of Greece Other people * Paul the Deacon or Paulus Diaconus (c. 720 – c. 799), Italian Benedictine monk *Paul (father of Maurice), the father of Maurice, By ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Loeffler
Friedrich August Johannes Loeffler (; 24 June 18529 April 1915) was a German bacteriologist at the University of Greifswald. Biography He obtained his M.D. degree from the University of Berlin in 1874. He worked with Robert Koch from 1879 to 1884Isaac Asimov, ''Asimov's Biographical Encyclopedia of Science and Technology'', 2nd Revised edition as an assistant in the Imperial Health Office in Berlin. In 1884, he became staff physician at the Friedrich Wilhelm Institute in Berlin, and four years later became professor at the University of Greifswald. His development of original methods of staining rendered an important and lasting service to bacteriology. Early in his career, he began a study of parasitic diseases. Among his discoveries was the organism causing diphtheria (''Corynebacterium diphtheriae'') and the cause of foot-and-mouth disease (Aphthovirus). His description of the diphtheria bacillus, published in 1884, was the originating cause of an antitoxin treatment. He also c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Contagium Vivum Fluidum
''Contagium vivum fluidum'' (Latin: "contagious living fluid") was a phrase first used to describe a virus, and underlined its ability to slip through the finest-mesh filters then available, giving it almost liquid properties. Martinus Beijerinck (1851–1931), a Dutch microbiologist and botanist, first used the term when studying the tobacco mosaic virus, becoming convinced that the virus had a liquid nature. In 1892, Dmitri Ivanovsky had discovered that the cause of tobacco mosaic disease could pass through Chamberland's porcelain filter. He noted these findings but felt that they could only have resulted from a cracked filter. It was left to Beijerinck, in 1898, to put forward the idea that the pathogen was small enough to pass through the filter routinely used to trap bacteria. Ivanovsky, irked that Beijerinck had not cited him, recreated Beijerinck's experimental set-up and demonstrated that particles of ink were small enough to pass through the filter, thus leaving the p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toxin
A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849–1919) and is derived from the word toxic. Toxins can be small molecules, peptides, or proteins that are capable of causing disease on contact with or absorption by body tissues interacting with biological macromolecules such as enzymes or cellular receptors. Toxins vary greatly in their toxicity, ranging from usually minor (such as a bee sting) to potentially fatal even at extremely low doses (such as botulinum toxin). Toxins are largely secondary metabolites, which are organic compounds that are not directly involved in an organism's growth, development, or reproduction, instead often aiding it in matters of defense. Terminology Toxins are often distinguished from other chemical agents strictly based on their biological origin. Le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobacco Mosaic Virus
''Tobacco mosaic virus'' (TMV) is a positive-sense single-stranded RNA virus species in the genus ''Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves (hence the name). TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by W.M. Stanley. It has a similar size to the largest synthetic molecule, known as PG5 History In 1886, Adolf Mayer first described the tobacco mosaic disease that could be transferred between plants, similar to bacterial infections. In 1892, Dmitri Ivanovsky gave the first concrete evidence for the existence of a non-bacterial infect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dmitry Ivanovsky
Dmitri Iosifovich Ivanovsky (alternative spelling ''Dmitrii'' or ''Dmitry Iwanowski''; russian: Дми́трий Ио́сифович Ивано́вский; 28 October 1864 – 20 June 1920) was a Russian botanist, the co-discoverer of :viruses (1892) and one of the founders of virology. Life Ivanovsky was born in the village of Nizy, Gdov Uyezd. He studied at the University of Saint Petersburg under Andrei Famintsyn in 1887, when he was sent to Ukraine and Bessarabia to investigate a tobacco disease causing great damage to plantations located there at the time. Three years later, he was assigned to look into a similar disease occurrence of tobacco plants, this time raging in the Crimea region. He discovered that both incidents of disease were caused by an extremely minuscule infectious agent, capable of permeating porcelain Chamberland filters, something which bacteria could never do. He described his findings in an article (1892) and a dissertation (1902). Then he worked at ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wageningen
Wageningen () is a municipality and a historic city in the central Netherlands, in the province of Gelderland. It is famous for Wageningen University, which specialises in life sciences. The municipality had a population of in , of which many thousands are students from over 150 countries. Demograpics Inhabitants by nationality 71,68% is Dutch, 28,32% has a migration background. Geography Wageningen is situated on the north bank of the Nederrijn (the Dutch portion of the Lower Rhine) part of the Gelderse valley (Dutch: Gelderse Vallei) and the Veluwe, of which the southwest hill is called the ''Wageningse Berg''. Wageningen can be reached by car from highways A12 via the N781, A15 via the N233 and N225, and A50 via the N225, and from the Ede-Wageningen railway station via a 20-minute bus drive to the Wageningen central terminal (see below)., ''Topographic map of the municipality of Wageningen, July 2013 (click to enlarge)'' History The oldest known settlements in the Wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Adolf Mayer
Adolf Eduard Mayer (9 August 184325 December 1942) was a German agricultural chemist whose work on tobacco mosaic disease played an important role in the discovery of tobacco mosaic virus and viruses in general. Mayer was born in 1843 into the family of a high school teacher in Oldenburg. His mother was a daughter of renowned German chemist Leopold Gmelin. From 1860 to 1862 he studied mathematics and chemistry at the Karlsruhe Institute of Technology. In 1862 he enrolled at the University of Heidelberg, where in 1864 he graduated summa cum laude with a Ph.D. in chemistry, physics, and mathematics. In 1879, while Mayer held the position of the director of the Agricultural Experiment Station at Wageningen in the Netherlands, he was asked by Dutch farmers to study a peculiar disease affecting the tobacco plant. Mayer published a paper in 1886 on the disease, which he named "mosaic disease of tobacco", and described its symptoms in detail. He demonstrated that the disease can be tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chamberland Filter
A Chamberland filter, also known as a Pasteur–Chamberland filter, is a porcelain water filter invented by Charles Chamberland in 1884. It was developed after Henry Doulton, Henry Doulton's ceramic water filter of 1827. It is similar to the Berkefeld filter in principle. Design The filter consists of a permeable unglazed porcelain tube (called bisque) that contains a ring of enameled porcelain through which the inflow pipe fits. The core of the porcelain is made up of a metal pipe with holes through which water flows out and is collected. Inflow is pressurized so filtration occurs under force. There are 13 types: ''L1'' to ''L13''. L1 filters have the coarsest pore size while L13 have the finest. Usefulness The Pasteur-Chamberland filter is as useful as other ceramic and porcelain filters. It is a good bacterial water filter used mainly as a high volume water filter.Textbook of Microbiology by Ananthanarayan and Panikar, The filter works more quickly when the water suppli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Chamberland
Charles Chamberland (; 12 March 1851 – 2 May 1908) was a French microbiologist from Chilly-le-Vignoble in the department of Jura who worked with Louis Pasteur. In 1884 he developed a type of filtration known today as the Chamberland filter or Chamberland-Pasteur filter, a device that made use of an unglazed porcelain bar. The filter had pores that were smaller than bacteria, thus making it possible to pass a solution containing bacteria through the filter, and having the bacteria completely removed from the solution. Chamberland was also credited for starting a research project that led to the invention of the autoclave An autoclave is a machine used to carry out industrial and scientific processes requiring elevated temperature and pressure in relation to ambient pressure and/or temperature. Autoclaves are used before surgical procedures to perform sterilizati ... device in 1879. References External links * Charles Edouard Chamberland and Louis Pasteur PasteurBre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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