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High-performance Integrated Virtual Environment
ThHigh-performance Integrated Virtual Environment(HIVE) is a distributed computing environment used for healthcare-IT and biological research, including analysis of Next Generation Sequencing (NGS) data, preclinical, clinical and post market data, adverse events, metagenomic data, etc. Currently it is supported and continuously developed by US Food and Drug Administration (government domain), George Washington University (academic domain), and by DNA-HIVE, WHISE-Global and Embleema (commercial domain). HIVE currently operates fully functionally within the US FDA supporting wide variety (+60) of regulatory research and regulatory review projects as well as for supporting MDEpiNet medical device postmarket registries. Academic deployments of HIVE are used for research activities and publications in NGS analytics, cancer research, microbiome research and in educational programs for students at GWU. Commercial enterprises use HIVE for oncology, microbiology, vaccine manufacturing, gene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIVE Logo For High-performance Integrated Virtual Environment
A hive may refer to a beehive, an enclosed structure in which some honey bee species live and raise their young. Hive or hives may also refer to: Arts * ''Hive'' (game), an abstract-strategy board game published in 2001 * "Hive" (song), a 2013 song by Earl Sweatshirt featuring Vince Staples and Casey Veggies * ''Hive'' (album), a 2022 album by alternative singer, producer, songwriter Sub Urban * "Hives", a song by IBOPA and later covered by Xiu Xiu as "Hives Hives" on the album '' Knife Play'' * H.I.V.E. ("Hierarchy of International Vengeance and Extermination"), a DC Comics villain organization * ''H.I.V.E.'' (series) ("Higher Institute of Villainous Education"), a series of young-adult novels * ''Hive Propolis'', stylized as ''hive , Propolis'', a science fiction transmedia series * Hive (comics), a Marvel Comics villain and character on ''Agents of S.H.I.E.L.D.'' * The Hives, a Swedish rock band Business * Hive (company), artificial intelligence services for businesse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Distributed Computing Environment
In computing, the Distributed Computing Environment (DCE) software system was developed in the early 1990s from the work of the Open Software Foundation (OSF), a consortium (founded in 1988) that included Apollo Computer (part of Hewlett-Packard from 1989), IBM, Digital Equipment Corporation, and others. The DCE supplies a framework and a toolkit for developing client/server applications. The framework includes: * a remote procedure call (RPC) mechanism known as DCE/RPC * a naming (directory) service * a time service * an authentication service * a distributed file system (DFS) known as DCE/DFS DCE represented a big step in the direction of standardization of architectures, which had previously been manufacturer-dependent. Like the OSI model, DCE has not seen much success in practical implementation; however, its underlying concepts have had more substantial influence over subsequent efforts. History Open Software Foundation (OSF) came about to a large degree as part of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DNA Sequencing
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. The rapid speed of sequencing attained with m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Metadata
Metadata is "data that provides information about other data", but not the content of the data, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of Statistical data type, statistical data. * Statistical metadata – also called process data, may describe processes that collect, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Application Programming Interface
An application programming interface (API) is a way for two or more computer programs to communicate with each other. It is a type of software interface, offering a service to other pieces of software. A document or standard that describes how to build or use such a connection or interface is called an ''API specification''. A computer system that meets this standard is said to ''implement'' or ''expose'' an API. The term API may refer either to the specification or to the implementation. In contrast to a user interface, which connects a computer to a person, an application programming interface connects computers or pieces of software to each other. It is not intended to be used directly by a person (the end user) other than a computer programmer who is incorporating it into the software. An API is often made up of different parts which act as tools or services that are available to the programmer. A program or a programmer that uses one of these parts is said to ''call'' tha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Federal Information Security Management Act Of 2002
The Federal Information Security Management Act of 2002 (FISMA, , ''et seq.'') is a United States federal law enacted in 2002 as Title III of the E-Government Act of 2002 (, ). The act recognized the importance of information security to the economic and national security interests of the United States. The act requires each federal agency to develop, document, and implement an agency-wide program to provide information security for the information and information systems that support the operations and assets of the agency, including those provided or managed by another agency, contractor, or other source. FISMA has brought attention within the federal government to cybersecurity and explicitly emphasized a "risk-based policy for cost-effective security." FISMA requires agency program officials, chief information officers, and inspectors general (IGs) to conduct annual reviews of the agency's information security program and report the results to Office of Management and Budge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics Algorithms
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for ''in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics Software
The list of bioinformatics software tools can be split up according to the license used: * List of proprietary bioinformatics software *List of open-source bioinformatics software Alternatively, here is a categorization according to the respective bioinformatics subfield specialized on: *Sequence analysis software **List of sequence alignment software **List of alignment visualization software **Alignment-free sequence analysis **De novo sequence assemblers **List of gene prediction software ** List of disorder prediction software ** List of Protein subcellular localization prediction tools ** List of phylogenetics software ** List of phylogenetic tree visualization software ** :Metagenomics_software *Structural biology software **List of molecular graphics systems **List of protein-ligand docking software ** List of RNA structure prediction software ** List of software for protein model error verification **List of protein secondary structure prediction programs **List of protein st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
