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Heroin-assisted Treatment
Heroin-assisted treatment (HAT), or diamorphine assisted treatment, refers to a type of Medication-Assisted Treatment (MAT) where semi-synthetic heroin is prescribed to opiate addicts who do not benefit from, or cannot tolerate, treatment with one of the established drugs used in opiate replacement therapy such as methadone or buprenorphine (brand name Subutex). For this group of patients, heroin-assisted treatment has proven superior in improving their social and health situation. It has also been shown to save money, as it significantly reduces costs incurred by trials, incarceration, health interventions and delinquency. It has also drastically reduced overdose deaths in the countries utilizing it, as patients take their dose in a controlled, professionally supervised setting, and Narcan (naloxone) is on hand in the case of an accidental overdose. Opiate related overdoses in the U.S. kill around 70,000 people per year. Heroin-assisted treatment is fully a part of the nation ...
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US Timeline
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country Continental United States, primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five major unincorporated territories, nine United States Minor Outlying Islands, Minor Outlying Islands, and 326 Indian reservations. The United States is also in Compact of Free Association, free association with three Oceania, Pacific Island Sovereign state, sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Palau, Republic of Palau. It is the world's List of countries and dependencies by area, third-largest country by both land and total area. It shares land borders Canada–United States border, with Canada to its north and Mexico–United States border, with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 m ...
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Belgium
Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to the southwest, and the North Sea to the northwest. It covers an area of and has a population of more than 11.5 million, making it the 22nd most densely populated country in the world and the 6th most densely populated country in Europe, with a density of . Belgium is part of an area known as the Low Countries, historically a somewhat larger region than the Benelux group of states, as it also included parts of northern France. The capital and largest city is Brussels; other major cities are Antwerp, Ghent, Charleroi, Liège, Bruges, Namur, and Leuven. Belgium is a sovereign state and a federal constitutional monarchy with a parliamentary system. Its institutional organization is complex and is structured on both regional ...
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Substance Dependence
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption of the drug. A ''drug addiction'', a distinct concept from substance dependence, is defined as compulsive, out-of-control drug use, despite negative consequences. An ''addictive drug'' is a drug which is both rewarding and reinforcing. ΔFosB, a gene transcription factor, is now known to be a critical component and common factor in the development of virtually all forms of behavioral and drug addictions, but not dependence. The International Classification of Diseases classifies substance dependence as a mental and behavioural disorder. Within the framework of the 4th edition of the ''Diagn ...
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Constipation
Constipation is a bowel dysfunction that makes bowel movements infrequent or hard to pass. The stool is often hard and dry. Other symptoms may include abdominal pain, bloating, and feeling as if one has not completely passed the bowel movement. Complications from constipation may include hemorrhoids, anal fissure or fecal impaction. The normal frequency of bowel movements in adults is between three per day and three per week. Babies often have three to four bowel movements per day while young children typically have two to three per day. Constipation has many causes. Common causes include slow movement of stool within the colon, irritable bowel syndrome, and pelvic floor disorders. Underlying associated diseases include hypothyroidism, diabetes, Parkinson's disease, celiac disease, non-celiac gluten sensitivity, colon cancer, diverticulitis, and inflammatory bowel disease. Medications associated with constipation include opioids, certain antacids, calcium channel blockers, ...
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Opioid Antagonist
An opioid antagonist, or opioid receptor antagonist, is a receptor antagonist that acts on one or more of the opioid receptors. Naloxone and naltrexone are commonly used opioid antagonist drugs which are competitive antagonists that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors. This effectively blocks the receptor, preventing the body from responding to opioids and endorphins. Some opioid antagonists are not pure antagonists but do produce some weak opioid partial agonist effects, and can produce analgesic effects when administered in high doses to opioid-naive individuals. Examples of such compounds include nalorphine and levallorphan. However, the analgesic effects from these specific drugs are limited and tend to be accompanied by dysphoria, most likely due to additional agonist action at the κ-opioid receptor. As they induce opioid withdrawal effects in people who are taking, or have recently used, opioid full agonists, the ...
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Black Market
A black market, underground economy, or shadow economy is a clandestine market or series of transactions that has some aspect of illegality or is characterized by noncompliance with an institutional set of rules. If the rule defines the set of goods and services whose production and distribution is prohibited by law, non-compliance with the rule constitutes a black market trade since the transaction itself is illegal. Parties engaging in the production or distribution of prohibited goods and services are members of the . Examples include the illegal drug trade, prostitution (where prohibited), illegal currency transactions, and human trafficking. Violations of the tax code involving income tax evasion in the . Because tax evasion or participation in a black market activity is illegal, participants attempt to hide their behavior from the government or regulatory authority. Cash is the preferred medium of exchange in illegal transactions since cash transactions are less-easi ...
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Supervised Injection Facilities
Supervised injection sites (SIS) are medically supervised facilities designed to provide a hygienic environment in which people are able to consume illicit recreational drugs intravenously and prevent deaths due to drug overdoses. The legality of such a facility is dependent by location and political jurisdiction. Supervised injection sites are part of a harm reduction approach towards drug problems. The facilities provide sterile injection equipment, information about drugs and basic health care, treatment referrals, access to medical staff, and, at some facilities, counseling. Most programs prohibit the sale or purchase of recreational drugs at the facility. Terminology They are also known as ''overdose prevention centers (OPC)'', ''supervised injection facilities'', ''safe consumption rooms'', ''safe injection sites'', ''safe injection rooms'', ''fix rooms'', ''fixing rooms'', ''safer injection facilities (SIF)'', ''drug consumption facilities (DCF)'', ''drug consumption room ...
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Harm Reduction
Harm reduction, or harm minimization, refers to a range of public health policies designed to lessen the negative social and/or physical consequences associated with various human behaviors, both legal and illegal. Harm reduction is used to decrease negative consequences of recreational drug use and sexual activity without requiring abstinence, recognizing that those unable or unwilling to stop can still make positive change to protect themselves and others. Harm reduction is most commonly applied to approaches that reduce adverse consequences from drug use, and harm reduction programs now operate across a range of services and in different regions of the world. As of 2020, some 86 countries had one or more programs using a harm reduction approach to substance use, primarily aimed at reducing blood-borne infections resulting from use of contaminated injecting equipment. Needle-exchange programmes reduce the likelihood of people who use heroin and other substances sharing the ...
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Drug Free America Foundation
The Drug Free America Foundation (DFAF) is a 501(c)(3) nonprofit organization founded in 1976 by former US Ambassador Mel Sembler, his wife Betty Sembler (), and Joseph Zappala as Straight, Inc., renamed The Straight Foundation, Inc. in 1985 and Drug Free America Foundation in 1995. Originally a drug rehabilitation program for adolescents, it faced multiple lawsuits for abuse of its patients. The organization no longer operates rehabilitation programs, and now "develops and promotes policies" opposing illegal drug use, drug addiction, and the decriminalization of cannabis and other drugs. It is a non-governmental organization (NGO) in Special Consultative Status with the United Nations Economic and Social Council. History Origins In 1976, Mel Sembler, Betty Sembler, and Joseph Zappala established the foundation as Straight, Inc. in St. Petersburg, Florida, with James E. Hartz, a clinical psychologist, as its first director. The organizers hoped to replace The Seed, a co ...
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Swiss People's Party
The Swiss People's Party (german: Schweizerische Volkspartei, SVP; rm, Partida populara Svizra, PPS), also known as the Democratic Union of the Centre (french: Union démocratique du centre, UDC; it, Unione Democratica di Centro, UDC), is a national-conservative, right-wing populist political party in Switzerland. Chaired by Marco Chiesa, it is the largest party in the Federal Assembly, with 53 members of the National Council and 6 of the Council of States. The SVP originated in 1971 as a merger of the Party of Farmers, Traders and Independents (BGB) and the Democratic Party, while the BGB, in turn, had been founded in the context of the emerging local farmers' parties in the late 1910s. The SVP initially did not enjoy any increased support beyond that of the BGB, retaining around 11% of the vote through the 1970s and 1980s. This changed however during the 1990s, when the party underwent deep structural and ideological changes under the influence of Christoph Blocher; the SVP ...
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Transnational Institute
The Transnational Institute (TNI), is an international non-profit research and advocacy think tank that was founded in 1974, Amsterdam, Netherlands. According to their website, the organization promotes a "... just, democratic and sustainable world." History TNI was founded in 1974 in Amsterdam by Eqbal Ahmad, who was the organization's first director. Initially it operated as an international arm of the Institute for Policy Studies. In 1976 the director of the institute (Orlando Letelier) was assassinated by the Chilean secret police as ordered by Augusto Pinochet. Pauline Tiffen is chair of the supervisory board of the TNI. The activist Susan George is president of the TNI. The members of the institute are involved in the civil society and the associative life of their respective countries. Based in Amsterdam, the permanent team of TNI consisted of twenty nine people in 2021. Work The TNI publishes research papers, books and organises seminars and debates. Its members i ...
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United Nations Office On Drugs And Crime
The United Nations Office on Drugs and Crime (UNODC; French: ''Office des Nations unies contre la drogue et le crime'') is a United Nations office that was established in 1997 as the Office for Drug Control and Crime Prevention by combining the United Nations International Drug Control Program (UNDCP) and the Crime Prevention and Criminal Justice Division in the United Nations Office at Vienna and was renamed the United Nations Office on Drugs and Crime in 2002. The agency's focus is the trafficking in and abuse of illicit drugs, crime prevention and criminal justice, international terrorism, and political corruption. It is a member of the United Nations Development Group. In 2016–2017 it had an estimated biannual budget of US$700 million. History The United Nations International Drug Control Program (UNDCP) and the Crime Prevention and Criminal Justice Division in the United Nations Office at Vienna were merged to form the Office for Drug Control and Crime Prevention. This ...
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