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Henry Halliday (paediatrician)
Henry Lewis Halliday (29 November 1945 – 12 November 2022) was a British-Irish peaditrician and neonatologist. In 2021, Halliday was awarded the James Spence Medal for research into neonatology, for coordinating two of the largest neonatal multicentre trials for prevention and treatment of a number of neonatal respiratory illnesses and for a breakthrough in the development of a new lung surfactant that brought relief to very small babies suffering from infant respiratory distress syndrome (RDS). Life Halliday was one of four siblings, the eldest of four brothers. His father Louis Halliday was an accountant, while his mother Gladys was a shopkeeper. Halliday attended school at the Belfast Royal Academy before deciding to study medicine. He matriculated in 1965 at Queen's University Belfast medical school and graduated in 1970. In 1977, Halliday married Marjorie Dalziel who was an intensive care nurse. The couple had three children, Joy, Gail & Brian Joshua, all of whom bec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belfast
Belfast ( , ; from ga, Béal Feirste , meaning 'mouth of the sand-bank ford') is the capital and largest city of Northern Ireland, standing on the banks of the River Lagan on the east coast. It is the 12th-largest city in the United Kingdom and the second-largest in Ireland. It had a population of 345,418 . By the early 19th century, Belfast was a major port. It played an important role in the Industrial Revolution in Ireland, briefly becoming the biggest linen-producer in the world, earning it the nickname "Linenopolis". By the time it was granted city status in 1888, it was a major centre of Irish linen production, tobacco-processing and rope-making. Shipbuilding was also a key industry; the Harland and Wolff shipyard, which built the , was the world's largest shipyard. Industrialisation, and the resulting inward migration, made Belfast one of Ireland's biggest cities. Following the partition of Ireland in 1921, Belfast became the seat of government for Northern Ireland ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Garth McClure
Garth may refer to: Places *Garth, Alberta, Canada *Garth, Bridgend, a village in south Wales :* Garth railway station (Bridgend) *Garth, Ceredigion, small village in Wales *Garth, Powys, a village in mid Wales :* Garth railway station (Powys) *Garth Hill, The Garth, Garth Hill or Garth Mountain, a mountain near Cardiff, Wales *Garth, one of many other minor place names in the United Kingdom Buildings and structures *Garth (Guilsfield), a historic house in Guilsfield, Montgomeryshire, UK * Castle Garth, a medieval fortification in Newcastle upon Tyne, England *Garth Pier, a Grade II listed structure in Bangor, Gwynedd, North Wales *Garth Castle, home to Clan Stewart of Atholl, north-west of Aberfeldy, Scotland Arts and entertainment * ''Garth'' (comic strip), published in the British newspaper ''Daily Mirror'' from 1943 to 1997 *Planet Garth, setting of David Brin's novel ''The Uplift War'' People and fictional characters *Garth (name), a list of people and fictional characters ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karolinska University Hospital
The Karolinska University Hospital ( sv, Karolinska universitetssjukhuset) is a teaching hospital affiliated with Karolinska Institutet in Stockholm, Sweden, with two major sites in the municipalities of Solna and Huddinge. The hospital network is the second largest in Sweden, after Sahlgrenska University Hospital. The present day Karolinska University Hospital is the result of a 2004 merger between the former Huddinge University Hospital (''Huddinge universitetssjukhus'') in Huddinge, south of Stockholm, and the Karolinska Hospital (''Karolinska sjukhuset'') in Solna, north of Stockholm. The new hospital has about 15,000 employees and 1,340 patient beds. The Karolinska University Hospital is closely affiliated with the Karolinska Institutet. It incorporates the Astrid Lindgren Children's hospital in Solna and the Children's Hospital in Huddinge. The Karolinska University Hospital in Solna is being replaced by the New Karolinska Solna University Hospital. New Karolinska Solna ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tore Curstedt
Tore Curstedt (born 1946 in Piteå) is a Swedish physician. Curstedt is primarily known for the development of the synthetic lung surfactant known as Corusurf along with Bengt Robertson Bengt A. Robertson was a Swedish physician and perinatal pathologist. Robertson was primarily known for the development of the synthetic lung surfactant known as Corusurf that brought relief to very small babies suffering from infant respiratory .... Life Curstedt is married to Sol-Britt Curstedt, who is also a physician. The couple have two adult children and five grandchildren. References {{DEFAULTSORT:Curstedt, Tore 1946 births Karolinska Institute alumni Living people ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poractant Alfa
Poractant alfa is a pulmonary surfactant sold under the brand name Curosurf by Chiesi Farmaceutici. Poractant alfa is an extract of natural porcine lung surfactant. As with other surfactants, marked improvement on oxygenation may occur within minutes of the administration of poractant alfa. The new generic form of surfactant is Varasurf (Sheep Lung Surfactant) developed in PersisGen Co. and commercialized by ArnaGen Pharmad. It has fully comparable quality profile with Curosurf. Pharmacology Each milliliter of poractant alfa contains 80 mg of surfactant (extract) that includes 76 mg of phospholipids and 1 mg of protein of which 0.2 mg is surfactant protein B (SP-B). Depending on local country registration, CUROSURF is available in 1.5 mL vials, 3.0 mL vials, and/or twin packs containing two 1.5 mL vials. The amount of phospholipids is calculated from the content of phosphorus and contains 55 mg of phosphatidylcholine of which 30 mg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bengt Robertson
Bengt A. Robertson was a Swedish physician and perinatal pathologist. Robertson was primarily known for the development of the synthetic lung surfactant known as Corusurf that brought relief to very small babies suffering from infant respiratory distress syndrome (RDS). From 1974 to 2000 he was the director of the division for experimental perinatal pathology in the department of women and child Health at the Karolinska Institute. In 1996 he was awarded the King Faisal International Prize in Medicine together with Tetsurō Fujiwara for contributions to the understanding of neonatal medicine. Life Robertson was born and grew up in Stockholm. As a child he attended the Södra Latins Gymnasium in the Södermalm area of Stockholm, leaving in 1953. Having decided to become a physician, Robertson attended the Karolinska Institute, a medical universiy and graduated Master of Science in Medicine (Swedish: Läkarexamen) in 1960. Robertson followed the MD with a Doctor of Philosophy d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alec Bangham
Alec Douglas Bangham FRS (10 November 1921 Manchester – 9 March 2010 Great Shelford) was a British biophysicist who first studied blood clotting mechanisms but became well known for his research on liposomes and his invention of clinically useful artificial lung surfactants. Life Bangham was the son of Donald Bangham, and Edith Kerby. He studied at the Downs School, and then Bryanston School, and proceeded to earn an MB MS in medicine from University College London. He was appointed to Addenbrooke's Hospital, where he served as a pathologist, in the Royal Army Medical Corps, becoming a captain in 1948. Bangham worked at the Babraham Institute in Cambridge from 1952 to 1982. He is best known for his research on liposomes. Family He was married to Rosalind; they had four children and eleven grandchildren. His brother was Derek Bangham. Awards *1965 doctorate of medicine from London University *1977 Fellow of the Royal Society *1981 Fellow of University College London *199 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colin J Morley
Colin may refer to: * Colin (given name) * Colin (surname) * ''Colin'' (film), a 2008 Cannes film festival zombie movie * Colin (horse) (1905–1932), thoroughbred racehorse * Colin (humpback whale), a humpback whale calf abandoned north of Sydney, Australia, in August 2008 * Colin (river), a river in France * Colin (security robot), in ''Mostly Harmless'' of ''The Hitchhiker's Guide to the Galaxy'' series by Douglas Adams * Tropical Storm Colin (other) See also *Collin (other) *Kolin (other) Kolin may refer to: *Kolín, a town in the Central Bohemian Region, Czech Republic **Kolín District * Starý Kolín, a municipality and village near Kolín, Czech Republic * Kolin, Louisiana, unincorporated place * Kolin, Montana * Kolin, West Pom ... * Colyn {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
High-density Lipoprotein
High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. They are typically composed of 80–100 proteins per particle (organized by one, two or three ApoA. HDL particles enlarge while circulating in the blood, aggregating more fat molecules) and transporting up to hundreds of fat molecules per particle. Overview Lipoproteins are divided into five subgroups, by density/size (an inverse relationship), which also correlates with function and incidence of cardiovascular events. Unlike the larger lipoprotein particles, which deliver fat molecules to cells, HDL particles remove fat molecules from cells. The lipids carried include cholesterol, phospholipids, and triglycerides, amounts of each are variable. Increasing concentrations of HDL particles are associated with decreasing accumulation of atherosclerosis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dipalmitoylphosphatidylcholine
Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to a phosphatidylcholine head-group. It is the main constituent of pulmonary surfactants, which reduces the work of breathing and prevents alveolar collapse during breathing. It also plays an important role in the study of liposomes and human bilayers. Lung surfactant Lung surfactant (LS) is a surface-active material produced by most air-breathing animals for the purpose of reducing the surface tension of the water layer where gas exchange occurs in the lungs, given that the movements due to inhalation and exhalation may cause damage if there is not enough energy to sustain alveolar structural integrity. The monolayer formed by the LS on the interface is composed primarily of phospholipids (80%), in addition to proteins (12%) and neutral lipids (8%). Among the phospholipids, the most prevalent one is phosphatidylcholine (PC, or lecithin) (70–85%), whic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patent Ductus Arteriosus
''Patent ductus arteriosus'' (PDA) is a medical condition in which the ''ductus arteriosus'' fails to close after birth: this allows a portion of oxygenated blood from the left heart to flow back to the lungs by flowing from the aorta, which has a higher pressure, to the pulmonary artery. Symptoms are uncommon at birth and shortly thereafter, but later in the first year of life there is often the onset of an increased work of breathing and failure to gain weight at a normal rate. With time, an uncorrected PDA usually leads to pulmonary hypertension followed by right-sided heart failure. The ''ductus arteriosus'' is a fetal blood vessel that normally closes soon after birth. In a PDA, the vessel does not close, but remains ''patent'' (open), resulting in an abnormal transmission of blood from the aorta to the pulmonary artery. PDA is common in newborns with persistent respiratory problems such as hypoxia, and has a high occurrence in premature newborns. Premature newborns are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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