Bengt Robertson
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Bengt A. Robertson was a Swedish physician and perinatal pathologist. Robertson was primarily known for the development of the synthetic
lung surfactant Pulmonary surfactant is a surface-active complex of phospholipids and proteins formed by type II alveolar cells. The proteins and lipids that make up the surfactant have both hydrophilic and hydrophobic regions. By adsorbing to the air-water inte ...
known as Corusurf that brought relief to very small babies suffering from
infant respiratory distress syndrome Infantile respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants c ...
(RDS). From 1974 to 2000 he was the director of the division for experimental perinatal pathology in the department of women and child Health at the Karolinska Institute. In 1996 he was awarded the King Faisal International Prize in Medicine together with Tetsurō Fujiwara for contributions to the understanding of
neonatal medicine Neonatology is a subspecialty of pediatrics that consists of the medical care of newborn infants, especially the ill or premature newborn. It is a hospital-based specialty, and is usually practised in neonatal intensive care units (NICUs). The ...
.


Life

Robertson was born and grew up in Stockholm. As a child he attended the Södra Latins Gymnasium in the
Södermalm Södermalm, often shortened to just Söder, is a district and island in central Stockholm. Overview The district covers the large island of the same name (formerly called ''Åsön''). Although Södermalm usually is considered an island, wat ...
area of Stockholm, leaving in 1953. Having decided to become a physician, Robertson attended the
Karolinska Institute The Karolinska Institute (KI; sv, Karolinska Institutet; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Karolinska Institute is consist ...
, a medical universiy and graduated Master of Science in Medicine (Swedish: Läkarexamen) in 1960. Robertson followed the MD with a
Doctor of Philosophy A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common Academic degree, degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields ...
degree and was awarded a doctorate in 1968. His thesis was titled: "The intrapulmonary arterial pattern in normal infancy and in transposition of the great arteries".


Career

From 1974 to 2000 he was director the Division of Experimental Perinatal Pathology at the Karolinska Institute.


Surfactant Research

When Robertson was a visiting professor at the University of Toronto in the department of pathology, he met the
obstetrician Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surgi ...
Göran Enhörning who at the time was based at the
Toronto Western Hospital The Toronto Western Hospital (TWH) is a major research and teaching hospital in Toronto, Ontario, Canada. It is part of the University Health Network (UHN). It has 256 beds, with 46,000 visits to its emergency department annually. It is known for ...
. Enhörning who was also from Stockholm like Robertson, would became his principle collaborator. In January 1964 the first preliminary study on the use of synthetic surfactant beta-gamma-dipalmitoyl-L-alpha-lecithin (DPL) that was delivered by nebulizer to 11 infants with RDS. Two trials were conducted in that used nebulised synthetic surfactant that was composed of synthetic
dipalmitoylphosphatidylcholine Dipalmitoylphosphatidylcholine (DPPC) is a phospholipid (and a lecithin) consisting of two C16 palmitic acid groups attached to a phosphatidylcholine head-group. It is the main constituent of pulmonary surfactants, which reduces the work of breath ...
(DPPC), showed negative results in the treatment of RDS. In 1972, Bengt and Enhörning developed research to discover the reasons for the failure of nebulised synthetic surfactant. They showed that when natural surfactant was installed directly into the
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
of premature rabbits took place, normal lung expansion was achieved, and the animals survived. In the autumn of 1984, Bengt became the leader of a group of neonatologist and surfactant researchers, known as the "The Collaborative European Multicenter Study Group", who were formed to test Curosurf in the first large international multicentre clinical trial.


Honours

Robertson received many honours throughout his life. In 1996, he was first recognised when he was awarded the
King Faisal International Prize The King Faisal Prize ( ar, جائزة الملك فيصل, formerly King Faisal International Prize), is an annual award sponsored by King Faisal Foundation presented to "dedicated men and women whose contributions make a positive difference". T ...
. Two years later in 1998, Robertson along with Tore Curstedt was awarded the Hilda and Alfred Eriksson Prize by the
Royal Swedish Academy of Sciences The Royal Swedish Academy of Sciences ( sv, Kungliga Vetenskapsakademien) is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special ...
. In 2002, he was awarded the Erich Saling Maternité Prize given by the European Association of Perinatal Medicine. This was followed in 2004 with the awarding of the Lars Werkö Prize by the Swedish Heart Lung Foundation along with Tore Curstedt. In 2023, Robertson was awarded the singular honour of having an award named after himself, when the European Academy of Paediatric Societies created the Bengt Robertson Award for research into the neonatal lung.


Publications

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References


Citation


Bibliography

* Biography articles needing translation from German Wikipedia 1935 births 2008 deaths 20th-century Swedish physicians Karolinska Institute alumni {{Sweden-scientist-stub