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Hendrik Streeck
Hendrik Streeck (born 7 August 1977 in Göttingen) is a German researcher of human immunodeficiency virus, epidemiologist and clinical trialist. He is professor of virology and the director of the Institute of Virology and HIV Research at the University Bonn. Early life and education Streeck studied medicine at the Charite University, Berlin. After his graduation he started to work as a postdoctoral fellow at the Ragon Institute of Massachusetts General Hospital, the Massachusetts Institute of Technology, and Harvard Medical School and obtained his PhD from the University of Bonn, and part-time at the Partners AIDS Research Center, Massachusetts General Hospital and Harvard Medical School. Career In 2009 Streeck was promoted to Instructor in Medicine and in 2011 to Assistant Professor at Harvard Medical School. In September 2012 he was recruited to the United States Military HIV Research Program, Bethesda, where he became the Chief of the Cellular Immunology Section a ...
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Göttingen
Göttingen (, , ; nds, Chöttingen) is a college town, university city in Lower Saxony, central Germany, the Capital (political), capital of Göttingen (district), the eponymous district. The River Leine runs through it. At the end of 2019, the population was 118,911. General information The origins of Göttingen lay in a village called ''Gutingi, ''first mentioned in a document in 953 AD. The city was founded northwest of this village, between 1150 and 1200 AD, and adopted its name. In Middle Ages, medieval times the city was a member of the Hanseatic League and hence a wealthy town. Today, Göttingen is famous for its old university (''Georgia Augusta'', or University of Göttingen, "Georg-August-Universität"), which was founded in 1734 (first classes in 1737) and became the most visited university of Europe. In 1837, seven professors protested against the absolute sovereignty of the House of Hanover, kings of Kingdom of Hanover, Hanover; they lost their positions, but be ...
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COVID-19 Pandemic In Germany
The COVID-19 pandemic in Germany has resulted in confirmed cases of COVID-19 and deaths. On 27 January 2020, the first case in Germany was confirmed near Munich, Bavaria. By mid February, the arising cluster of cases had been fully contained. On 25 and 26 February, multiple cases related to the Italian outbreak were detected in Baden-Württemberg. A carnival event on 15 February in Heinsberg, North Rhine-Westphalia, was attended by a man identified as positive on 25 February; in the outbreak which subsequently developed from infected participants, authorities were mostly no longer able to trace the likely chains of infections. On 9 March, the first two deaths in Germany were reported from Essen and Heinsberg. New clusters were introduced in other regions via Heinsberg as well as via people arriving from China, Iran and Italy, from where non-Germans could arrive by plane until 17–18 March. From 13 March, German states mandated school and kindergarten c ...
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1977 Births
Events January * January 8 – Three bombs explode in Moscow within 37 minutes, killing seven. The bombings are attributed to an Armenian separatist group. * January 10 – Mount Nyiragongo erupts in eastern Zaire (now the Democratic Republic of the Congo). * January 17 ** 49 marines from the and are killed as a result of a collision in Barcelona harbour, Spain. * January 18 ** Scientists identify a previously unknown bacterium as the cause of the mysterious Legionnaires' disease. ** Australia's worst railway disaster at Granville, a suburb of Sydney, leaves 83 people dead. ** SFR Yugoslavia Prime minister Džemal Bijedić, his wife and 6 others are killed in a plane crash in Bosnia and Herzegovina. * January 19 – An Ejército del Aire CASA C-207C Azor (registration T.7-15) plane crashes into the side of a mountain near Chiva, on approach to Valencia Airport in Spain, killing all 11 people on board. * January 20 – Jimmy Carter is sworn in as the 39th Pres ...
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Federal Ministry Of Health (Germany)
The Federal Ministry of Health (german: link=no, Bundesministerium für Gesundheit), abbreviated BMG, is a cabinet-level ministry of the Federal Republic of Germany. It is the highest German federal government department responsible for health. The ministry is officially located in Bonn and with a second office, which houses the ministry's management, location in Berlin. History The Federal Ministry of Health was founded in 1961; in 1969 it was merged with the Federal Ministry for Family and Youth to create the new Federal Ministry for Youth, Family and Health. In 1991, the Federal Ministry of Health was restored. In 2002, it was expanded to include social affairs and renamed "Federal Ministry of Health and Social Security" ('). It was headed by the Federal Minister for Health and Social Security. Its portfolio included one part of the former Federal Ministry of Labour and the Social Order. The other part of the latter was added to the portfolio of the newly created Feder ...
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Coronavirus
Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, they cause respiratory tract infections that can range from mild to lethal. Mild illnesses in humans include some cases of the common cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal varieties can cause SARS, MERS and COVID-19, which is causing the ongoing pandemic. In cows and pigs they cause diarrhea, while in mice they cause hepatitis and encephalomyelitis. Coronaviruses constitute the subfamily ''Orthocoronavirinae'', in the family ''Coronaviridae'', order '' Nidovirales'' and realm '' Riboviria''. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately 26 to 32 kilobases, one of the largest among RNA viruses. They have characteristic club-shaped spikes that project from their surface, which in electr ...
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COVID-19 Case-Cluster-Study
The COVID-19 Case-Cluster-Study – colloquially, Heinsberg study, also known as Heinsbergprotokoll and HEINSBERG PROTOKOLL. – is a study about the COVID-19 pandemic in Gangelt. The study was commissioned and is co-financed by the government of North Rhine-Westphalia and is led by Hendrik Streeck. In the public sphere, the marketing agency StoryMachine presented its results on Facebook and Twitter. Private enterprises also co-financed the study. The results of the study garnered cross-national media attention. The study aimed to determine lethality of and immunity to SARS-CoV-2; it also estimated the number of unrecorded cases. Despite the fact that sample size does not determine the representativeness of a study, principal investigator Streeck claims, they examined more persons than recommended by the World Health Organization, the study would "thus be statistically absolutely representative". Criticism One weakness of the study was the calculation of the IFR, whi ...
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International AIDS Society
The International AIDS Society (IAS) is the world's largest association of HIV/AIDS professionals, with 11,600 members from over 170 countries , including clinicians, people living with HIV, service providers, policy makers and others. It aims to reduce the global impact of AIDS through collective advocacy. Founded in 1988, IAS headquarters are located in Geneva, and its president since August 2022 is Sharon Lewin. The IAS hosts the biennial International AIDS Conference, the IAS Conference on HIV Science, and the HIV Research for Prevention Conference. History The IAS is a non-profit organization founded in 1988, with a mandate to organize the International AIDS Conference. Initially, the IAS headquarters were in Stockholm, and Lars-Olof Kallings was the secretary general from 1988 until 2003. In 2004, the IAS restructured its organization, expanded the number of professional staff and moved the headquarters to Geneva. The move was intended to strengthen organizational links ...
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Sexually Transmitted Infection
Sexually transmitted infections (STIs), also referred to as sexually transmitted diseases (STDs) and the older term venereal diseases, are infections that are Transmission (medicine), spread by Human sexual activity, sexual activity, especially Sexual intercourse, vaginal intercourse, anal sex, and oral sex. STIs often do not initially cause symptoms, which results in a risk of passing the infection on to others. Symptoms and signs of STIs may include vaginal discharge, penile discharge, genital ulcers, ulcers on or around the genitals, and pelvic pain. Some STIs can cause infertility. Bacterial STIs include Chlamydia infection, chlamydia, gonorrhea, and syphilis. Viral STIs include genital herpes, HIV/AIDS, and genital warts. Parasitic STIs include trichomoniasis. STI diagnostic tests are usually easily available in the developed world, but they are often unavailable in the developing world. Some vaccinations may also decrease the risk of certain infections including Hepa ...
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Maputo
Maputo (), formerly named Lourenço Marques until 1976, is the Capital city, capital, and largest city of Mozambique. Located near the southern end of the country, it is within of the borders with Eswatini and South Africa. The city has a population of 1,088,449 (as of 2017) distributed over a land area of . The Metropolitan Maputo, Maputo metropolitan area includes the neighbouring city of Matola, and has a total population of 2,717,437. Maputo is a port city, with an economy centered on commerce. It is also noted for its vibrant cultural scene and distinctive, eclectic architecture. Maputo is situated on Maputo Bay, a large natural bay on the Indian Ocean, near where the rivers Tembe, Mbuluzi, Matola and Infulene converge. The city consists of seven administrative divisions, which are each subdivided into Quarter (urban subdivision), quarters or ''bairros''. The city is surrounded by Maputo Province, but is administered as a self-contained, separate Provinces of Mozambique, pr ...
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Follicular B Helper T Cells
Follicular helper T cells (also known as follicular B helper T cells and abbreviated as TFH), are antigen-experienced CD4+ T cells found in the periphery within B cell follicles of secondary lymphoid organs such as lymph nodes, spleen and Peyer's patches, and are identified by their constitutive expression of the B cell follicle homing receptor CXCR5. Upon cellular interaction and cross-signaling with their cognate follicular (Fo B) B cells, TFH cells trigger the formation and maintenance of germinal centers through the expression of CD40 ligand (CD40L) and the secretion of IL-21 and IL-4. TFH cells also migrate from T cell zones into these seeded germinal centers, predominantly composed of rapidly dividing B cells mutating their Ig genes. Within germinal centers, TFH cells play a critical role in mediating the selection and survival of B cells that go on to differentiate either into long-lived plasma cells capable of producing high affinity antibodies against foreign antigen ...
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HIV Vaccine
An HIV vaccine is a potential vaccine that could be either a preventive vaccine or a therapeutic vaccine, which means it would either protect individuals from being infected with HIV or treat HIV-infected individuals. It is thought that an HIV vaccine could either induce an immune response against HIV (active vaccination approach) or consist of preformed antibodies against HIV (passive vaccination approach). Two active vaccine regimens, studied in the RV 144 and Imbokodo trials, showed they can prevent HIV in some individuals. However, the protection was in relatively few individuals, and was not long lasting. For these reasons, no HIV vaccines have been licensed for the market yet. Difficulties in development In 1984, after it was confirmed that HIV caused AIDS, the United States Health and Human Services Secretary Margaret Heckler declared that a vaccine would be available within two years. However, priming the adaptive immune system to recognize the viral envelope protein ...
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