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Heinz Fraenkel-Conrat
Heinz Ludwig Fraenkel-Conrat (July 29, 1910 – April 10, 1999) was a biochemist, famous for his research on viruses. Early life Fraenkel-Conrat was born in Breslau/Germany. He was the son of Lili Conrat and Professor Ludwig Fraenkel, director of the Women's Clinic of the University of Breslau, Germany. His father, Ludwig Fraenkel, was a prominent gynecologist and medical researcher who published regarding endocrine function, social gynecology, and sexology during the first decades of the 20th century, and was one of the legion of scientists summarily dismissed from their positions by the Nazis. Academic career He received an MD from the University of Breslau in 1933. Due to the rise of Nazism in Germany he left for Scotland in 1933 and finished his PhD at the University of Edinburgh (1936). After completing his doctorate, he emigrated to the United States, becoming a naturalized citizen in 1941. In the 1940s Fraenkel-Conrat visited his sister and brother-in-law, biochemist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Naturalized Citizen
Naturalization (or naturalisation) is the legal act or process by which a non-citizen of a country may acquire citizenship or nationality of that country. It may be done automatically by a statute, i.e., without any effort on the part of the individual, or it may involve an application or a motion and approval by legal authorities. The rules of naturalization vary from country to country but typically include a promise to obey and uphold that country's laws and taking and subscribing to an oath of allegiance, and may specify other requirements such as a minimum legal residency and adequate knowledge of the national dominant language or culture. To counter multiple citizenship, some countries require that applicants for naturalization renounce any other citizenship that they currently hold, but whether this renunciation actually causes loss of original citizenship, as seen by the host country and by the original country, will depend on the laws of the countries involved. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oakland Medical Center
Kaiser Oakland Medical Center is a hospital in Oakland, California. It is located at the intersection of Broadway and West MacArthur Boulevard, immediately north of Downtown. It is the flagship hospital of Kaiser Permanente, the largest managed care organization in the United States, through its Kaiser Foundation Hospitals division. History The Oakland Medical Center was the first of the Kaiser Permanente hospitals, and opened in 1942 as a result of the acquisition of the Fabiola charity hospital (which operated from 1887 to 1932 before being sold to Samuel Merritt Hospital) by the Permanente Foundation, founded by industrialist Henry J. Kaiser and physician Sidney Garfield. This was the first modern Health maintenance organization (HMO) hospital after the experiment of using an HMO model was found to be successful among the 90,000 Richmond Kaiser Shipyards workers in the Richmond, California, Field Hospital. Several additions and renovations followed over the decades, notab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha amino acids appear in the genetic code. Amino acids can be classified according to the locations of the core structural functional groups, as Alpha and beta carbon, alpha- , beta- , gamma- or delta- amino acids; other categories relate to Chemical polarity, polarity, ionization, and side chain group type (aliphatic, Open-chain compound, acyclic, aromatic, containing hydroxyl or sulfur, etc.). In the form of proteins, amino acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robley Williams
Robley Cook Williams (October 13, 1908 – January 3, 1995) was an early biophysicist and virologist. He served as the first president of the Biophysical Society. Career Williams attended Cornell University on an athletic scholarship, completing a B.S. in 1931 and a Ph.D. in physics in 1935. While at Cornell, he was selected for membership in the Telluride House and the Quill and Dagger society. Williams began his career as a researcher as an assistant professor of astronomy at the University of Michigan, and from 1945, associate professor of physics. A growing fascination with viruses led him to leave Michigan in 1950, when he was invited to the University of California, Berkeley by Wendell Stanley, to serve as a professor at the newly created Department of Virology. Research Together with Heinz Fraenkel-Conrat, Williams studied the Tobacco mosaic virus, and showed that a functional virus could be created out of purified RNA and a protein coat. That same year, he was elected t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Holmes Ribgrass Virus
''Ribgrass mosaic virus'' (RMV) is a species of ''Tobamovirus ''Tobamovirus'' is a genus of positive-strand RNA viruses in the family '' Virgaviridae.'' Many plants, including tobacco, potato, tomato, and squash, serve as natural hosts. Diseases associated with this genus include: necrotic lesions on leave ...''. It is an RNA-containing virus with rod-shape particles. It can be found in many wild plant species. This virus does not itself produce serious epidemic diseases, but it served as the inciting pathogen of a necrotic virus disease in burly tobacco.William S.Klug - Michael R.Cummings.1997.Concepts of genetics.Prentice-Hall Inc. References External links Descriptions of Plant Viruses Virgaviridae Viral plant pathogens and diseases {{Virus-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tobacco Mosaic Virus
''Tobacco mosaic virus'' (TMV) is a positive-sense single-stranded RNA virus species in the genus ''Tobamovirus'' that infects a wide range of plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns, such as "mosaic"-like mottling and discoloration on the leaves (hence the name). TMV was the first virus to be discovered. Although it was known from the late 19th century that a non-bacterial infectious disease was damaging tobacco crops, it was not until 1930 that the infectious agent was determined to be a virus. It is the first pathogen identified as a virus. The virus was crystallised by W.M. Stanley. It has a similar size to the largest synthetic molecule, known as PG5 History In 1886, Adolf Mayer first described the tobacco mosaic disease that could be transferred between plants, similar to bacterial infections. In 1892, Dmitri Ivanovsky gave the first concrete evidence for the existence of a non-bacterial infect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brazil
Brazil ( pt, Brasil; ), officially the Federative Republic of Brazil (Portuguese: ), is the largest country in both South America and Latin America. At and with over 217 million people, Brazil is the world's fifth-largest country by area and the seventh most populous. Its capital is Brasília, and its most populous city is São Paulo. The federation is composed of the union of the 26 States of Brazil, states and the Federal District (Brazil), Federal District. It is the largest country to have Portuguese language, Portuguese as an List of territorial entities where Portuguese is an official language, official language and the only one in the Americas; one of the most Multiculturalism, multicultural and ethnically diverse nations, due to over a century of mass Immigration to Brazil, immigration from around the world; and the most populous Catholic Church by country, Roman Catholic-majority country. Bounded by the Atlantic Ocean on the east, Brazil has a Coastline of Brazi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
São Paulo
São Paulo (, ; Portuguese for 'Saint Paul') is the most populous city in Brazil, and is the capital of the state of São Paulo, the most populous and wealthiest Brazilian state, located in the country's Southeast Region. Listed by the GaWC as an alpha global city, São Paulo is the most populous city proper in the Americas, the Western Hemisphere and the Southern Hemisphere, as well as the world's 4th largest city proper by population. Additionally, São Paulo is the largest Portuguese-speaking city in the world. It exerts strong international influences in commerce, finance, arts and entertainment. The city's name honors the Apostle, Saint Paul of Tarsus. The city's metropolitan area, the Greater São Paulo, ranks as the most populous in Brazil and the 12th most populous on Earth. The process of conurbation between the metropolitan areas around the Greater São Paulo (Campinas, Santos, Jundiaí, Sorocaba and São José dos Campos) created the São Paulo Macrometr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Instituto Butantan
Instituto Butantan (in modern Portuguese, Instituto Butantã, ) is a Brazilian biologic research center located in Butantã, in the western part of the city of São Paulo, Brazil. Instituto Butantan is a public institution affiliated with the São Paulo State Secretariat of Health and considered one of the major scientific centers in the world. Butantan is the largest immunobiologicals and biopharmaceuticals producer in Latin America (and one of the largest in the world). It is world-renowned for its collection of venomous snakes, as well as those of venomous lizards, spiders, insects and scorpions. By extracting the reptiles' and insects' venoms, the Institute develops antivenoms and medicines against many diseases, which include tuberculosis, rabies, tetanus and diphtheria. History The Institute was founded by the Brazilian physician and biomedical scientist Vital Brazil in 1901, according to Pasteur Institute paradigm, i.e., by combining in the same institution medical rese ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venom
Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism. Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and haemotoxins, which disrupt blood clotting. Venomous animals cause tens of thousa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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