Heinrich Sachs
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Heinrich Sachs
Heinrich Sachs (1863 - 1928) was a late 19th and early 20th century German neurologist and neuroanatomist best known for his atlas of the brain's white matter White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution .... Scientific career Heinrich Sachs was born in Halberstadt, Germany, in 1863. He studied medicine in Berlin, graduating in 1885 with a dissertation on amyotrophic lateral sclerosis. After practicing as a physician for a few years, he joined neuropathologist Carl Wernicke's laboratory at University Hospital, Breslau, where he studied spatial perception and gained a postdoctoral qualification (habilitation) in psychiatry and neurology in 1897. In 1892, Sachs published the first installment of an ambitious and informative atlas of the brain's white matter, with a focus on the ana ...
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Neurologist
Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal cord and the peripheral nerves. Neurological practice relies heavily on the field of neuroscience, the scientific study of the nervous system. A neurologist is a physician specializing in neurology and trained to investigate, diagnose and treat neurological disorders. Neurologists treat a myriad of neurologic conditions, including stroke, seizures, movement disorders such as Parkinson's disease, autoimmune neurologic disorders such as multiple sclerosis, headache disorders like migraine and dementias such as Alzheimer's disease. Neurologists may also be involved in clinical research, clinical trials, and basic or translational research. While neurology is a nonsurgical specialty, its corresponding surgical specialty is neurosurgery. Histor ...
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Probst Bundle
Longitudinal callosal fascicles, or Probst bundles, are aberrant bundles of axons that run in a front-back (antero-posterior) direction rather than a left-right direction between the cerebral hemispheres. They are characteristic of patients with agenesis of the corpus callosum and are due to failure of the callosally-projecting neurons (mostly layer 2/3 pyramidal neurons) to extend axons across the midline and therefore form the corpus callosum. The inability of these axons to cross the midline results in anomalous axonal guidance and front-to-back projections within each hemisphere, rather than connecting between the hemispheres in the normal corpus callosum. These longitudinal callosal fascicles were originally described by Moriz Probst in 1901 by gross anatomical observation. More recently, these anomalies are detected by magnetic resonance imaging or diffusion tensor imaging Diffusion-weighted magnetic resonance imaging (DWI or DW-MRI) is the use of specific MRI sequences a ...
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German Neuroscientists
German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * Germa ...
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1928 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ...
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1863 Births
Events January–March * January 1 – Abraham Lincoln signs the Emancipation Proclamation during the third year of the American Civil War, making the abolition of slavery in the Confederate states an official war goal. It proclaims the freedom of 3.1 million of the nation's four million slaves and immediately frees 50,000 of them, with the rest freed as Union armies advance. * January 2 – Lucius Tar Painting Master Company (''Teerfarbenfabrik Meirter Lucius''), predecessor of Hoechst, as a worldwide chemical manufacturing brand, founded in a suburb of Frankfurt am Main, Germany. * January 4 – The New Apostolic Church, a Christian and chiliastic church, is established in Hamburg, Germany. * January 7 – In the Swiss canton of Ticino, the village of Bedretto is partly destroyed and 29 killed, by an avalanche. * January 8 ** The Yorkshire County Cricket Club is founded at the Adelphi Hotel, in Sheffield, England. ** American Civil War – ...
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Lessie Sachs
Lessie Sachs (1897–1942) was a German-born American poet and artist who was active during World War I and World War II. Biography Lessie Sachs was born in 1897 in Breslau, then a city in the German Empire. She was the only child of neurologist Heinrich Sachs. Sachs attended schools in Breslau and Munich, where she studied arts and crafts. Sachs primarily wrote lyrical love poems. Her earliest poems were published in the journal ''Simplicissimus''. A number of German newspapers (e.g. the ''Vossische Zeitung'') also published her work, and a few of her poems were set to music and broadcast on the radio. In 1933, Sachs married Austrian composer and pianist Josef Wagner, with whom she had a daughter, Dorothée. Sachs was Jewish, and in 1939 she and her family emigrated to the United States and settled in New York. Some of Sachs' work was then published in the New York-based German-Jewish newspaper ''Aufbau''. Although best known as a poet, Sachs was also an artist. At least one ...
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Neurosis
Neurosis is a class of functional mental disorders involving chronic distress, but neither delusions nor hallucinations. The term is no longer used by the professional psychiatric community in the United States, having been eliminated from the ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM) in 1980 with the publication of DSM III. However, it is still used in the ICD-10 Chapter V F40–48. Neurosis should not be mistaken for ''psychosis'', which refers to a loss of touch with reality. Nor should it be mistaken for ''neuroticism'', a fundamental personality trait proposed in the Big Five personality traits theory. Etymology The term is derived from the Greek word ''neuron'' (νεῦρον, 'nerve') and the suffix ''-osis'' (-ωσις, 'diseased' or 'abnormal condition'). The term ''neurosis'' was coined by Scottish doctor William Cullen in 1769 to refer to "disorders of sense and motion" caused by a "general affection of the nervous system." Cullen used the te ...
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Aphasia
Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in the Global North. Aphasia can also be the result of brain tumors, brain infections, or neurodegenerative diseases (such as dementias). To be diagnosed with aphasia, a person's speech or language must be significantly impaired in one (or more) of the four aspects of communication following acquired brain injury. Alternatively, in the case of progressive aphasia, it must have significantly declined over a short period of time. The four aspects of communication are auditory comprehension, verbal expression, reading and writing, and functional communication. The difficulties of people with aphasia can range from occasional trouble finding words, to losing the ability to speak, read, or write; intelligence, however, is unaffected. Expressive lan ...
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Vertical Occipital Fasciculus
The vertical occipital fasciculus is a fascicle of white matter running vertically in the rear of the brain. It is found at least in primates. It "is the only major fiber bundle connecting dorsolateral and ventrolateral visual cortex." Early discovery Originally depicted by Carl Wernicke, who called it the ''senkrechte Occipitalbündel'' (vertical occipital bundle), the region was practically lost to scientific knowledge during the twentieth century. Theodor Meynert had described the brain's other white matter tracts as being horizontally oriented, and did not accept Wernicke's finding. Heinrich Obersteiner named the area the "fasciculus occipitalis perpendicularis", and Heinrich Sachs named the area the "stratum profundum convexitatis". It appeared in a 1918 edition of Gray's Anatomy, but fell into obscurity. A diffusion tensor imaging (DTI) study in 2004 noted an area of short-range association fibers in the lateral occipital lobe The occipital lobe is one of the four ...
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Theodor Meynert
Theodor Hermann Meynert (15 June 1833 – 31 May 1892) was a German-Austrian psychiatrist, neuropathologist and anatomist born in Dresden. Meynert believed that disturbances in brain development could be a predisposition for psychiatric illness and that certain psychoses are reversible. In 1861 he earned his medical doctorate, and in 1875 became director of the psychiatric clinic associated with the University of Vienna. Some of his better known students in Vienna were Josef Breuer, Sigmund Freud, who in 1883 worked at Meynert's psychiatric clinic, and Julius Wagner-Jauregg, who introduced fever treatment for syphilis. Meynert later distanced himself from Freud because of the latter's involvement with practices such as hypnosis. Meynert also ridiculed Freud's idea of male hysteria; though some authors believe this to be due to his own hidden suffering of the illness, prompting a reconciliation with Freud near to his death. Other famous students of Meynert's were Russian neuropsychi ...
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Callosal
The corpus callosum (Latin for "tough body"), also callosal commissure, is a wide, thick nerve tract, consisting of a flat bundle of commissural fibers, beneath the cerebral cortex in the brain. The corpus callosum is only found in placental mammals. It spans part of the longitudinal fissure, connecting the left and right cerebral hemispheres, enabling communication between them. It is the largest white matter structure in the human brain, about in length and consisting of 200–300 million axonal projections. A number of separate nerve tracts, classed as subregions of the corpus callosum, connect different parts of the hemispheres. The main ones are known as the genu, the rostrum, the trunk or body, and the splenium. Structure The corpus callosum forms the floor of the longitudinal fissure that separates the two cerebral hemispheres. Part of the corpus callosum forms the roof of the lateral ventricles. The corpus callosum has four main parts – individual nerve tr ...
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Parietal Lobe
The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus. The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin (touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe. Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the cortical homunculus (Latin: "little man") in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule and in ...
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