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Hartog Jakob Hamburger
Hartog Jakob or Hartog Jacob Hamburger (9 March 1859 – 4 January 1924) was a Dutch physiologist, born in Alkmaar. After completing the Hogere Burgerschool in Alkmaar, Hamburger studied chemistry at Utrecht University, where he received his doctorate in 1883, on the determination of urea in urine. He subsequently worked with Utrecht ophthalmologist and physiologist Franciscus Cornelis Donders for seven years, and completed a medical degree. From 1888 he lectured in physiology and pathology at the National Veterinary School, also in Utrecht. In 1896, he invented the crystalloid solution known as Hamburger's solution or normal saline. Based on plant-based experiments by botanist Hugo de Vries, he developed a salt solution that was thought to have the same osmolality as human blood and therefore did not cause haemolysis of red blood cells. It is uncertain whether the saline was ever originally intended for intravenous administration. In 1901 he joined the University of Groningen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hartog J
Hartog and de/den Hartog(h) are Dutch surnames meaning "(the) duke" (modern Dutch ''hertog'').Hartog at the Database of Surnames in The Netherlands Hartog is also a Dutch Jewish given name and surname equivalent to German Herzog and Hirsch, derived from ''hert'' (Dutch for "deer"). People with these names include: Surname Hartog * Arie den Hartog (1941–2018), Dutch bicycle racer * (born 1954), Dutch field hockey player *[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chloride Shift
Chloride shift (also known as the Hamburger phenomenon or lineas phenomenon, named after Hartog Jakob Hamburger) is a process which occurs in a cardiovascular system and refers to the exchange of bicarbonate (HCO3−) and chloride (Cl−) across the membrane of red blood cells (RBCs). Mechanism Carbon dioxide (CO2) is produced in tissues as a byproduct of normal metabolism. It dissolves in the solution of blood plasma and into red blood cells (RBC), where carbonic anhydrase catalyzes its hydration to carbonic acid (H2CO3). Carbonic acid then spontaneously dissociates to form bicarbonate Ions (HCO3−) and a hydrogen ion (H+). In response to the decrease in intracellular pCO2, more CO2 passively diffuses into the cell. Cell membranes are generally impermeable to charged ions (i.e. H+, HCO3− ) but RBCs are able to exchange bicarbonate for chloride using the anion exchanger protein Band 3. Thus, the rise in intracellular bicarbonate leads to bicarbonate export and chloride intake ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academic Staff Of The University Of Groningen
An academy ( Attic Greek: Ἀκαδήμεια; Koine Greek Ἀκαδημία) is an institution of secondary or tertiary higher learning (and generally also research or honorary membership). The name traces back to Plato's school of philosophy, founded approximately 385 BC at Akademia, a sanctuary of Athena, the goddess of wisdom and skill, north of Athens, Greece. Etymology The word comes from the ''Academy'' in ancient Greece, which derives from the Athenian hero, ''Akademos''. Outside the city walls of Athens, the gymnasium was made famous by Plato as a center of learning. The sacred space, dedicated to the goddess of wisdom, Athena, had formerly been an olive grove, hence the expression "the groves of Academe". In these gardens, the philosopher Plato conversed with followers. Plato developed his sessions into a method of teaching philosophy and in 387 BC, established what is known today as the Old Academy. By extension, ''academia'' has come to mean the accumulation, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Alkmaar
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dutch Physiologists
Dutch commonly refers to: * Something of, from, or related to the Netherlands * Dutch people () * Dutch language () Dutch may also refer to: Places * Dutch, West Virginia, a community in the United States * Pennsylvania Dutch Country People Ethnic groups * Germanic peoples, the original meaning of the term ''Dutch'' in English ** Pennsylvania Dutch, a group of early Germanic immigrants to Pennsylvania *Dutch people, the Germanic group native to the Netherlands Specific people * Dutch (nickname), a list of people * Johnny Dutch (born 1989), American hurdler * Dutch Schultz (1902–1935), American mobster born Arthur Simon Flegenheimer * Dutch Mantel, ring name of American retired professional wrestler Wayne Maurice Keown (born 1949) * Dutch Savage, ring name of professional wrestler and promoter Frank Stewart (1935–2013) Arts, entertainment, and media Fictional characters * Dutch (''Black Lagoon''), an African-American character from the Japanese manga and anime ''Black L ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1924 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1859 Births
Events January–March * January 21 – José Mariano Salas (1797–1867) becomes Conservative interim President of Mexico. * January 24 ( O. S.) – Wallachia and Moldavia are united under Alexandru Ioan Cuza (Romania since 1866, final unification takes place on December 1, 1918; Transylvania and other regions are still missing at that time). * January 28 – The city of Olympia is incorporated in the Washington Territory of the United States of America. * February 2 – Miguel Miramón (1832–1867) becomes Conservative interim President of Mexico. * February 4 – German scholar Constantin von Tischendorf rediscovers the ''Codex Sinaiticus'', a 4th-century uncial manuscript of the Greek Bible, in Saint Catherine's Monastery on the foot of Mount Sinai, in the Khedivate of Egypt. * February 14 – Oregon is admitted as the 33rd U.S. state. * February 12 – The Mekteb-i Mülkiye School is founded in the Ottoman Empire. * February 17 – French naval forces under Char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Groningen
Groningen (; gos, Grunn or ) is the capital city and main municipality of Groningen province in the Netherlands. The ''capital of the north'', Groningen is the largest place as well as the economic and cultural centre of the northern part of the country; as of December 2021, it had 235,287 inhabitants, making it the sixth largest city/municipality of the Netherlands and the second largest outside the Randstad. Groningen was established more than 950 years ago and gained city rights in 1245. Due to its relatively isolated location from the then successive Dutch centres of power (Utrecht, The Hague, Brussels), Groningen was historically reliant on itself and nearby regions. As a Hanseatic city, it was part of the North German trade network, but later it mainly became a regional market centre. At the height of its power in the 15th century, Groningen could be considered an independent city-state and it remained autonomous until the French era. Today Groningen is a university ci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Padua
The University of Padua ( it, Università degli Studi di Padova, UNIPD) is an Italian university located in the city of Padua, region of Veneto, northern Italy. The University of Padua was founded in 1222 by a group of students and teachers from Bologna. Padua is the second-oldest university in Italy and the world's fifth-oldest surviving university. In 2010, the university had approximately 65,000 students. In 2021, it was ranked second "best university" among Italian institutions of higher education with more than 40,000 students according to Censis institute, and among the best 200 universities in the world according to ARWU. History The university is conventionally said to have been founded in 1222 when a large group of students and professors left the University of Bologna in search of more academic freedom ('Libertas scholastica'). The first subjects to be taught were law and theology. The curriculum expanded rapidly, and by 1399 the institution had divided in two: a ''Univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Aberdeen
The University of Aberdeen ( sco, University o' 'Aiberdeen; abbreviated as ''Aberd.'' in List of post-nominal letters (United Kingdom), post-nominals; gd, Oilthigh Obar Dheathain) is a public university, public research university in Aberdeen, Scotland. It is an Ancient universities of Scotland, ancient university founded in 1495 when William Elphinstone, Bishop of Aberdeen and Lord Chancellor of Scotland, Chancellor of Scotland, petitioned Pope Alexander VI on behalf of James IV of Scotland, James IV, King of Scots to establish King's College, Aberdeen, King's College, making it Scotland's 3rd oldest university and the 5th oldest in the English-speaking world and the United Kingdom. Aberdeen is consistently ranked among the top 160 universities in the world and is ranked within the top 20 universities in the United Kingdom according to ''The Times'' and ''The Sunday Times'', and 13th in the UK according to ''The Guardian''. The university comprises three colleges—King's College ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Netherlands Academy Of Arts And Sciences
The Royal Netherlands Academy of Arts and Sciences ( nl, Koninklijke Nederlandse Akademie van Wetenschappen, abbreviated: KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed in the Trippenhuis in Amsterdam. In addition to various advisory and administrative functions it operates a number of research institutes and awards many prizes, including the Lorentz Medal in theoretical physics, the Dr Hendrik Muller Prize for Behavioural and Social Science and the Heineken Prizes. Main functions The academy advises the Dutch government on scientific matters. While its advice often pertains to genuine scientific concerns, it also counsels the government on such topics as policy on careers for researchers or the Netherlands' contribution to major international projects. The academy offers solicited and unsolicited advice to parliament, ministries, universities and research institutes, funding agencies and internationa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neutrophil Granulocyte
Neutrophils (also known as neutrocytes or heterophils) are the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. They form an essential part of the innate immune system, with their functions varying in different animals. They are formed from stem cells in the bone marrow and differentiated into subpopulations of neutrophil-killers and neutrophil-cagers. They are short-lived and highly mobile, as they can enter parts of tissue where other cells/molecules cannot. Neutrophils may be subdivided into segmented neutrophils and banded neutrophils (or bands). They form part of the polymorphonuclear cells family (PMNs) together with basophils and eosinophils. The name ''neutrophil'' derives from staining characteristics on hematoxylin and eosin ( H&E) histological or cytological preparations. Whereas basophilic white blood cells stain dark blue and eosinophilic white blood cells stain bright red, neutrophils stain a neutral pink. Normal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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