Haplogroup CZ (mtDNA)
In human mitochondrial genetics, the Haplogroup CZ is a human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup CZ is a descendant of haplogroup M8 and is a parent to the haplogroups C and Z. The C and Z subclades share a common ancestor dated to approximately 36,500 years ago.Behar et al., 2012b Distribution Today, CZ is found in eastern Asian, Central Asian, Siberian, indigenous American, and European populations, and is most common in Siberian populations. It is recognized by a genetic marker at 249d. Subclades Tree This phylogenetic tree of haplogroup CZ subclades is based on the paper by Mannis van Oven and Manfred Kayser ''Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation'' and subsequent published research. *M **M8 ***CZ ****C ****Z See also *Genealogical DNA test *Genetic genealogy *Human mitochondrial genetics *Population genetics *Human mitochondrial DNA haplogroups Humans (''Homo sapiens'') are the most abundant ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Haplogroup M8 (mtDNA)
In human mitochondrial genetics, Haplogroup M8 is a Human mitochondrial DNA haplogroup, human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup M8 is a descendant of Haplogroup M (mtDNA), haplogroup M. Haplogroup M8 is divided into subclades M8a, C and Z. Distribution It is an East Asian haplogroup. Today, haplogroup M8 is found at its highest frequency in indigenous populations of East Siberia such as Evenks, Evenk and Yukaghir people, Yukaghir. Haplogroup M8 is one of the most common mtDNA haplogroups among Yakuts, Yakut, Tuvans, Tuvan. Haplogroup C (mtDNA), Haplogroup C, the most major one of three subclades is highly distributed among the Indigenous peoples of the Americas, Amerindian and Indigienous peoples of East Siberia. Haplogroup Z, the other one of three subclades is highly distributed among Evens, Even from Kamchatka Peninsula, Kamchatka (8/39 Z1a2a, 3/39 Z1a3, 11/39 = 28.2% Z total), mtDNA Haplogroup M8a, not well known one of three subclades is highly distribu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ethnic Groups In Europe
Europeans are the focus of European ethnology, the field of anthropology related to the various ethnic groups that reside in the List of sovereign states and dependent territories in Europe, states of Europe. Groups may be defined by common genetic ancestry, common language, or both. Pan and Pfeil (2004) count 87 distinct "''peoples of Europe''", of which 33 form the majority population in at least one sovereign state, while the remaining 54 constitute ethnic minority, ethnic minorities. The total number of national minority populations in Europe is estimated at 105 million people, or 14% of 770 million Europeans.Christoph Pan, Beate Sibylle Pfeil (2002), Minderheitenrechte in Europa. Handbuch der europäischen Volksgruppen', Braumüller, (Google Books, snippet view). Als2006 reprint by Springer(Amazon, no preview) . The Russians are the most populous among Europeans, with a population of roughly 120 million. There are no universally accepted and precise definitions of the term ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Population Genetics
Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as adaptation, speciation, and population structure. Population genetics was a vital ingredient in the emergence of the modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, laboratory, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and adaptive dynamics, is its emphasis on such genetic phenomena as dominance, epi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Human Mitochondrial Genetics
Human mitochondrial genetics is the study of the genetics of human mitochondrial DNA (the DNA contained in human mitochondria). The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA). In humans, as in most multicellular organisms, mitochondrial DNA is inherited only from the mother's ovum. There are theories, however, that paternal mtDNA transmission in humans can occur under certain circumstances. Mitochondrial inheritance is therefore non-Mendelian, as Mendelian inheritance presumes that half the genetic material of a fertilized egg (zygote) derives from each parent. Eighty percent of mitochondrial DNA codes for mitochondrial RNA, and therefore most mitochondrial DNA mutations lead to functional problems, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genetic Genealogy
Genetic genealogy is the use of genealogical DNA tests, i.e., DNA profiling and DNA testing, in combination with traditional genealogical methods, to infer genetic relationships between individuals. This application of genetics came to be used by family historians in the 21st century, as DNA tests became affordable. The tests have been promoted by amateur groups, such as surname study groups or regional genealogical groups, as well as research projects such as the Genographic Project. As of 2019, about 30 million people had been tested. As the field developed, the aims of practitioners broadened, with many seeking knowledge of their ancestry beyond the recent centuries, for which traditional pedigrees can be constructed. History The investigation of surnames in genetics can be said to go back to George Darwin, a son of Charles Darwin and Charles' first cousin Emma Darwin. In 1875, George Darwin used surnames to estimate the frequency of first-cousin marriages and calculated t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genealogical DNA Test
A genealogical DNA test is a DNA-based test used in genetic genealogy that looks at specific locations of a person's genome in order to find or verify ancestral genealogical relationships, or (with lower reliability) to estimate the ethnic mixture of an individual. Since different testing companies use different ethnic reference groups and different matching algorithms, ethnicity estimates for an individual vary between tests, sometimes dramatically. Three principal types of genealogical DNA tests are available, with each looking at a different part of the genome and being useful for different types of genealogical research: autosomal (atDNA), mitochondrial (mtDNA), and Y-DNA. Autosomal tests may result in a large number of DNA matches to both males and females who have also tested with the same company. Each match will typically show an estimated degree of relatedness, i.e., a close family match, 1st-2nd cousins, 3rd-4th cousins, etc. The furthest degree of relationship is u ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Genetic Marker
A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change ( single nucleotide polymorphism, SNP), or a long one, like minisatellites. Background For many years, gene mapping was limited to identifying organisms by traditional phenotypes markers. This included genes that encoded easily observable characteristics such as blood types or seed shapes. The insufficient number of these types of characteristics in several organisms limited the mapping efforts that could be done. This prompted the development of gene markers which could identify genetic characteristics that are not readily observable in organisms (such as protein variation). Types Some commonly used types of genetic markers ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Siberia
Siberia ( ; rus, Сибирь, r=Sibir', p=sʲɪˈbʲirʲ, a=Ru-Сибирь.ogg) is an extensive geographical region, constituting all of North Asia, from the Ural Mountains in the west to the Pacific Ocean in the east. It has been a part of Russia since the latter half of the 16th century, after the Russians conquered lands east of the Ural Mountains. Siberia is vast and sparsely populated, covering an area of over , but home to merely one-fifth of Russia's population. Novosibirsk, Krasnoyarsk and Omsk are the largest cities in the region. Because Siberia is a geographic and historic region and not a political entity, there is no single precise definition of its territorial borders. Traditionally, Siberia extends eastwards from the Ural Mountains to the Pacific Ocean, and includes most of the drainage basin of the Arctic Ocean. The river Yenisey divides Siberia into two parts, Western and Eastern. Siberia stretches southwards from the Arctic Ocean to the hills of north-ce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Indigenous Peoples Of The Americas
The Indigenous peoples of the Americas are the inhabitants of the Americas before the arrival of the European settlers in the 15th century, and the ethnic groups who now identify themselves with those peoples. Many Indigenous peoples of the Americas were traditionally hunter-gatherers and many, especially in the Amazon basin, still are, but many groups practiced aquaculture and agriculture. While some societies depended heavily on agriculture, others practiced a mix of farming, hunting, and gathering. In some regions, the Indigenous peoples created monumental architecture, large-scale organized cities, city-states, chiefdoms, states, kingdoms, republics, confederacies, and empires. Some had varying degrees of knowledge of engineering, architecture, mathematics, astronomy, writing, physics, medicine, planting and irrigation, geology, mining, metallurgy, sculpture, and gold smithing. Many parts of the Americas are still populated by Indigenous peoples; some countries have ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Haplogroup C (mtDNA)
In human mitochondrial genetics, Haplogroup C is a human mitochondrial DNA (mtDNA) haplogroup. Origin Haplogroup C is believed to have arisen somewhere between the Caspian Sea and Lake Baikal some 24,000 years before present. It is a descendant of the haplogroup M. Haplogroup C shares six mutations downstream of the MRCA of haplogroup M with haplogroup Z and five mutations downstream of the MRCA of haplogroup M with other members of haplogroup M8. This macro-haplogroup is known as haplogroup M8'CZ or simply as haplogroup M8. Distribution Haplogroup C is found in Northeast Asia (including Siberia) and the Americas. In Eurasia, Haplogroup C is especially frequent among populations of arctic Siberia, such as Nganasans, Dolgans, Yakuts, Evenks, Evens, Yukaghirs, and Koryaks. Haplogroup C is one of five mtDNA haplogroups found in the indigenous peoples of the Americas, the others being A, B, D, and X. The subclades C1b, C1c, C1d, and C4c are found in the first people of the ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Indigenous Peoples Of Siberia
Siberia, including the Russian Far East, is a vast region spanning the northern part of the Asian continent, and forming the Asiatic portion of Russia. As a result of the Russian conquest of Siberia (17th to 19th centuries) and of the subsequent population movements during the Soviet era (1917-1991), the modern-day demographics of Siberia is dominated by ethnic Russians ( Siberiaks) and other Slavs. However, there remains a slowly increasing number of indigenous groups, between them, accounting for about 10% of the total Siberian population (about 4,500,000), some of which are closely genetically related to indigenous peoples of the Americas. History In Kamchatka, the Itelmens' uprisings against Russian rule in 1706, 1731, and 1741, were crushed. During the first uprising the Itelmen were armed with only stone weapons, but in later uprisings they used gunpowder weapons. The Russian Cossacks faced tougher resistance from the Koryaks, who revolted with bows and guns from 1745 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Central Asia
Central Asia, also known as Middle Asia, is a subregion, region of Asia that stretches from the Caspian Sea in the west to western China and Mongolia in the east, and from Afghanistan and Iran in the south to Russia in the north. It includes the former Soviet Union, Soviet republics of the Soviet Union, republics of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan, which are colloquially referred to as the "-stans" as the countries all have names ending with the Persian language, Persian suffix "-stan", meaning "land of". The current geographical location of Central Asia was formerly part of the historic region of Turkestan, Turkistan, also known as Turan. In the pre-Islamic and early Islamic eras ( and earlier) Central Asia was inhabited predominantly by Iranian peoples, populated by Eastern Iranian languages, Eastern Iranian-speaking Bactrians, Sogdians, Khwarezmian language, Chorasmians and the semi-nomadic Scythians and Dahae. After expansion by Turkic peop ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |