Hans Knöll
Hans Knöll (January 7, 1913– June 26, 1978) was a German physician and microbiologist. He was the director of the Central Institute of Microbiology and Experimental Therapy in Jena from 1953 to 1976, a member of the Academy of Sciences of the German Democratic Republic (i.e. of East Germany), and professor of bacteriology at the University of Jena. He was awarded the National Prize of the GDR in 1949 and 1952. In the late 1960s he got involved in an effort to save the historic center of Jena, protesting against the "socialist" urban development plans. Career In 1931 he started studying medicine at the University of Frankfurt on Main. A year later he joined the Nazi Party and the Sturmabteilung (SA). He quit the latter in 1935 (after the Night of the Long Knives). Little else is known about his political involvement during this period because his name does not appear in the 200,000-page records recovered from the Nazi Party Chancellery. He gained the Dr. med. degree in 1938. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Wiesbaden
Wiesbaden () is a city in central western Germany and the capital of the state of Hesse. , it had 290,955 inhabitants, plus approximately 21,000 United States citizens (mostly associated with the United States Army). The Wiesbaden urban area is home to approximately 560,000 people. Wiesbaden is the second-largest city in Hesse after Frankfurt, Frankfurt am Main. The city, together with nearby Frankfurt am Main, Darmstadt, and Mainz, is part of the Frankfurt Rhine Main Region, a metropolitan area with a combined population of about 5.8 million people. Wiesbaden is one of the oldest spa towns in Europe. Its name translates to "meadow baths", a reference to its famed hot springs. It is also internationally famous for its architecture and climate—it is also called the "Nice of the North" in reference to the city in France. At one time, Wiesbaden had 26 hot springs. , fourteen of the springs are still flowing. In 1970, the town hosted the tenth ''Hessentag Landesfest'' (En ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Schott AG
Schott AG is a German multinational glass company specializing in the manufacture of glass and glass-ceramics. Headquartered in Mainz, Germany, it is owned by the Carl Zeiss Foundation. The company's founder and namesake, Otto Schott, is credited with the invention of borosilicate glass. History Founding In 1884, Otto Schott, Ernst Abbe, Carl Zeiss and his son Roderich Zeiss founded the ''Glastechnische Laboratorium Schott & Genossen'' (Glass Technical Laboratory Schott & Associates) in Jena, which initially produced optical glasses for microscopes and telescopes. In 1891, the Carl Zeiss Foundation founded two years earlier by Ernst Abbe became a partner in the glass laboratory. Jena glass, an early borosilicate glass, was one of its early manufactured products. The invention of borosilicate glass, resistant to chemicals, heat and temperature change, paved the way for new technical glasses for thermometers, laboratory equipment and gas lamps. The company experience ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sarcina Maxima
''Sarcina maxima'' is a bacterium from the genus ''Sarcina'' which has been isolated from faeces of an elephant Elephants are the largest existing land animals. Three living species are currently recognised: the African bush elephant, the African forest elephant, and the Asian elephant. They are the only surviving members of the family Elephantidae .... References Bacteria described in 1888 Clostridiaceae {{Firmicutes-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Beutenberg Campus
The Beutenberg Campus is a science and research site situated in southern Jena, Germany. The physician Hans Knöll founded the first biomedical research institute at Beutenberg in 1950. From 1970, it was run as the Central Institute of Microbiology and Experimental Therapy (Zentralinstitut für Mikrobiologie und experimentelle Therapie - ZIMET) of the German Academy of Sciences at Berlin, Academy of Sciences of the GDR. From 1982 institutes focussing on physics were also set up on the site. Following German reunification in 1990, a multidisciplinary science and research centre was created in response to a recommendation by the German Council of Science and Humanities. The campus currently hosts nine research institutes. These include three Gottfried Wilhelm Leibniz Scientific Community, Leibniz Association institutes, two Max Planck Society institutes, one Fraunhofer Society institute, one institute funded by the State of Thuringia, as well as Friedrich Schiller University institut ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bacillus Calmette-Guérin
Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible. In areas where tuberculosis is not common, only children at high risk are typically immunized, while suspected cases of tuberculosis are individually tested for and treated. Adults who do not have tuberculosis and have not been previously immunized, but are frequently exposed, may be immunized, as well. BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Rates of protection against tuberculosis infection vary widely and protection lasts up to 20 years. Among children, it prevents about 20% from getting infected and among those who do get infected, it ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Habilitation
Habilitation is the highest university degree, or the procedure by which it is achieved, in many European countries. The candidate fulfills a university's set criteria of excellence in research, teaching and further education, usually including a dissertation. The degree, abbreviated "Dr. habil." (Doctor habilitatus) or "PD" (for "Privatdozent"), is a qualification for professorship in those countries. The conferral is usually accompanied by a lecture to a colloquium as well as a public inaugural lecture. History and etymology The term ''habilitation'' is derived from the Medieval Latin , meaning "to make suitable, to fit", from Classical Latin "fit, proper, skillful". The degree developed in Germany in the seventeenth century (). Initially, habilitation was synonymous with "doctoral qualification". The term became synonymous with "post-doctoral qualification" in Germany in the 19th century "when holding a doctorate seemed no longer sufficient to guarantee a proficient transfer o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Jenapharm
Jenapharm is a pharmaceutical company from Jena, Germany. Founded in 1950 in East Germany, the company focused from the beginning on the production and development of steroids. Due to the economic circumstances of the Eastern Bloc, the company initially used a unique process of steroid synthesis starting from hog bile, however this method was abandoned a decade later in favor of total synthesis. Initially the company produced a wide range of generic steroids, including corticosteroids, but later on it focused on anabolic steroids, estrogens and progestins. Prior to Germany's reunification Jenapharm was the only supplier of hormonal contraceptives in East Germany. It successfully marketed a number of drugs it had developed in collaboration with other East German chemists. Perhaps the most well known of these is Valette, which sold well in Germany in the 1990s. After the reunification, Jenapharm eventually became a subsidiary of Schering AG, which sold its generic therapeutics busin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those with ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nucleosides
Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed a nitrogenous base) and a five-carbon sugar (ribose or 2'-deoxyribose) whereas a nucleotide is composed of a nucleobase, a five-carbon sugar, and one or more phosphate groups. In a nucleoside, the anomeric carbon is linked through a glycosidic bond to the N9 of a purine or the N1 of a pyrimidine. Nucleotides are the molecular building-blocks of DNA and RNA. List of nucleosides and corresponding nucleobases The reason for 2 symbols, shorter and longer, is that the shorter ones are better for contexts where explicit disambiguation is superfluous (because context disambiguates) and the longer ones are for contexts where explicit disambiguation is judged to be needed or wise. For example, when discussing long nucleobase sequences in genomes, the CATG symbol system is much preferable to the Cyt-Ade-Thy-Gua symbol system (see '' N ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Fluorescent Microscopy
A fluorescence microscope is an optical microscope that uses fluorescence instead of, or in addition to, scattering, reflection, and attenuation or absorption, to study the properties of organic or inorganic substances. "Fluorescence microscope" refers to any microscope that uses fluorescence to generate an image, whether it is a simple set up like an epifluorescence microscope or a more complicated design such as a confocal microscope, which uses optical sectioning to get better resolution of the fluorescence image. Principle The specimen is illuminated with light of a specific wavelength (or wavelengths) which is absorbed by the fluorophores, causing them to emit light of longer wavelengths (i.e., of a different color than the absorbed light). The illumination light is separated from the much weaker emitted fluorescence through the use of a spectral emission filter. Typical components of a fluorescence microscope are a light source (xenon arc lamp or mercury-vapor lamp are ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |