H. Hugh Fudenberg
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H. Hugh Fudenberg
Herman Hugh Fudenberg (October 24, 1928March 15, 2014) was an American clinical immunologist and the sole identified member of the Neuro Immuno Therapeutics Research Foundation (NITRF). Fudenberg was a proponent of the discredited hypothesis that there was a connection between the MMR vaccine and autism. In 1995 Fudenberg's medical license was suspended for improperly obtaining controlled substances. Education He received his A.B. from UCLA in 1949 and his MD from the University of Chicago in 1953. Fudenberg received his M.A. in immunochemistry from Boston University in 1957. Career The areas of his research, conducted primarily in the 1960s and 1970s, included research into immunoglobulin and receptors for this molecule in human monocytes, as well as the ability of red blood cells to, in vitro, form "rosette" formations around peripheral blood lymphocytes. Fudenberg was hired by the Special Projects Unit of the Council for Tobacco Research in 1972, to study whether som ...
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New York City
New York, often called New York City or NYC, is the List of United States cities by population, most populous city in the United States. With a 2020 population of 8,804,190 distributed over , New York City is also the List of United States cities by population density, most densely populated major city in the United States, and is more than twice as populous as second-place Los Angeles. New York City lies at the southern tip of New York (state), New York State, and constitutes the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the world by urban area, urban landmass. With over 20.1 million people in its metropolitan statistical area and 23.5 million in its combined statistical area as of 2020, New York is one of the world's most populous Megacity, megacities, and over 58 million people live within of the city. New York City is a global city, global Culture of New ...
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Peripheral Blood Lymphocyte
Peripheral blood lymphocytes (PBL) are mature lymphocytes that circulate in the blood, rather than localising to organs (such as the spleen or lymph nodes). They comprise T cells, NK cells and B cells B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. They function in the humoral immunity component of the adaptive immune system. B cells produce antibody molecules which may be either secreted o .... References Lymphocytes {{lymphatic-stub ...
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Bone Marrow
Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. Bone marrow comprises approximately 5% of total body mass in healthy adult humans, such that a man weighing 73 kg (161 lbs) will have around 3.7 kg (8 lbs) of bone marrow. Human marrow produces approximately 500 billion blood cells per day, which join the systemic circulation via permeable vasculature sinusoids within the medullary cavity. All types of hematopoietic cells, including both myeloid and lymphoid lineages, are created in bone marrow; however, lymphoid cells must migrate to other lymphoid organs (e.g. thymus) in order to complete maturation. ...
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Brian Deer
Brian Deer is a British investigative reporter, best known for inquiries into the drug industry, medicine and social issues for ''The Sunday Times''. Deer's investigative nonfiction book, ''The Doctor Who Fooled the World,'' was published in September 2020 by Johns Hopkins University Press. Career After graduating in philosophy from the University of Warwick, he became editor and press officer for the Campaign for Nuclear Disarmament, and was a member of ''The Leveller'' magazine collective. Subsequently, he joined ''The Times'', then ''The Sunday Times'', first as a business news subeditor and then as a staff news reporter and feature writer. In the 1980s, under then ''Sunday Times'' editor Andrew Neil, Deer was the UK's first social affairs correspondent, and between 1990 and 1992 reported from the United States. Investigations In 1986, one of Deer's early investigations exposed research by British scientist Michael Briggs at Deakin University, Australia into the safety o ...
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Andrew Wakefield
Andrew Jeremy Wakefield (born September 3, 1956) is a British anti-vaccine activist, former physician, and discredited academic who was struck off the medical register for his involvement in ''The Lancet'' MMR autism fraud, a 1998 study that falsely claimed a link between the measles, mumps, and rubella (MMR) vaccine and autism. He has subsequently become known for anti-vaccination activism. Publicity around the 1998 study caused a sharp decline in vaccination uptake, leading to a number of outbreaks of measles around the world. He was a surgeon on the liver transplant programme at the Royal Free Hospital in London and became senior lecturer and honorary consultant in experimental gastroenterology at the Royal Free and University College School of Medicine. He resigned from his positions there in 2001, "by mutual agreement", then moved to the United States. In 2004, Wakefield co-founded and began working at the Thoughtful House research center (now renamed Johnson Center for ...
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Medical University Of South Carolina
The Medical University of South Carolina (MUSC) is a public medical school in South Carolina. It opened in 1824 in Charleston as a small private college aimed at training physicians and has since established hospitals and medical facilities across the state. It is one of the oldest continually operating schools of medicine in the United States and the oldest in the Deep South. The school's main building was designed by Charleston architect Albert W. Todd. The school has expanded into a state university with a medical center and six colleges for the education of health professionals, biomedical scientists, and other health care personnel. It also operates as a center for research and has a public hospital. Colleges College of Medicine History The College of Medicine began in 1823 with the incorporation of the Medical College of South Carolina, a private institution of the Medical Society of South Carolina. Seven Charleston physicians formed the initial faculty with 30 stude ...
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World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ...
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Rosette Test
Erythrocyte rosetting or E-rosetting is a phenomenon seen through a microscope where red blood cells ''(erythrocytes)'' are arranged around a central cell to form a cluster that looks like a flower. The red blood cells surrounding the cell form the ''petal,'' while the central cell forms the ''stigma'' of the flower shape. This formation occurs due to an immunological reaction between an epitope on the central cell's surface and a receptor or antibody on a red cell. The presence of E-rosetting can be used as a test for T cells although more modern tests such as immunohistochemistry are available. Rosetting is caused by parasites in the genus ''Plasmodium'' and is a cause of some malaria-associated symptoms. Rosetting techniques Three types of rosette techniques have been developed and used experimentally. Rosette test for Rh factor The ''Rosette test'' is performed on postpartum maternal blood to estimate the volume of fetal-maternal hemorrhage in case of an Rh negative mother ...
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University Of California, Berkeley
The University of California, Berkeley (UC Berkeley, Berkeley, Cal, or California) is a public land-grant research university in Berkeley, California. Established in 1868 as the University of California, it is the state's first land-grant university and the founding campus of the University of California system. Its fourteen colleges and schools offer over 350 degree programs and enroll some 31,800 undergraduate and 13,200 graduate students. Berkeley ranks among the world's top universities. A founding member of the Association of American Universities, Berkeley hosts many leading research institutes dedicated to science, engineering, and mathematics. The university founded and maintains close relationships with three national laboratories at Berkeley, Livermore and Los Alamos, and has played a prominent role in many scientific advances, from the Manhattan Project and the discovery of 16 chemical elements to breakthroughs in computer science and genomics. Berkeley is ...
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Peter Bent Brigham Hospital
Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Sunil Eappen serves as the hospital's current president. Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2020 '' U.S. News & World Report'' hospital rankings, BWH was ranked second in Massachusetts (behind MGH) and twelfth nationally. History Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospitals: Peter Bent Brigham Hospital (es ...
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Blood (journal)
''Blood'' is a peer-reviewed medical journal published by the American Society of Hematology. It was established by William Dameshek in 1946. The journal changed from semimonthly (24 times annually) to weekly publication at the start of 2009. It covers clinical and basic research in all areas of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematologic oncology. Abstracting and indexing ''Blood'' is indexed and abstracted by: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 25.476, and has a Journal Impact Factor rank of 1/76 in the Hematology category. References External l ...
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William Dameshek
William Dameshek (1900 in Voronezh – 1969) was an American hematologist. He graduated from Harvard College and Harvard Medical School and spent the early part of his career at Beth Israel Hospital (now Beth Israel Deaconess Medical Center). He was the founder of ''Blood'', the prime core clinical journal of hematology, in 1946. He is also credited with describing the concept of myeloproliferative diseases in 1951. In addition, he participated in the first studies of nitrogen mustard in various hematological malignancies, widely considered the first uses of chemotherapy in malignant diseases. Dr Dameshek was also the first one who described chronic lymphocytic leukemia (CLL), a common form of leukemia in adults. Dr. Dameshek served as president of the American Society of Hematology (ASH) in 1964. He made numerous contributions to ASH as well as the field of hematology and was the first editor of its journal ''Blood Blood is a body fluid in the circulatory system of huma ...
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