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Peter Bent Brigham Hospital
Brigham and Women's Hospital (BWH) is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts. Along with Massachusetts General Hospital, it is one of the two founding members of Mass General Brigham, the largest healthcare provider in Massachusetts. Sunil Eappen serves as the hospital's current president. Brigham and Women's Hospital conducts the second largest (behind MGH) hospital-based research program in the world, with an annual research budget of more than $630 million. Pioneering achievements at BWH have included the world's first successful heart valve operation and the world's first solid organ transplant. In the 2020 '' U.S. News & World Report'' hospital rankings, BWH was ranked second in Massachusetts (behind MGH) and twelfth nationally. History Brigham and Women's Hospital was established with the 1980 merger of three Harvard-affiliated hospitals: Peter Bent Brigham Hospital (e ...
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Mass General Brigham
Mass General Brigham (MGB) is a Boston-based non-profit hospital and physician network that includes Brigham and Women's Hospital (BWH) and Massachusetts General Hospital (MGH), two of the nation's most prestigious teaching institutions. It was founded in 1994 with H. Richard Nesson, MD, former president of Brigham and Women's Hospital as CEO of Mass General Brigham and Samuel O. Thier, MD, formerly president of Massachusetts General Hospital as president. Another member of the MGB network, McLean Hospital is the top ranked psychiatric hospital in the United States and maintains the world's largest neuroscientific and psychiatric research program in a private hospital. According to ''The Boston Globe'', by 2008, Mass General Brigham became Massachusetts' "largest private employer and its biggest healthcare provider, treating more than a third of hospital patients in the Boston metropolitan area". History In 1994, Brigham and Women's Hospital and Massachusetts General Hospital wer ...
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The Boston Globe
''The Boston Globe'' is an American daily newspaper founded and based in Boston, Massachusetts. The newspaper has won a total of 27 Pulitzer Prizes, and has a total circulation of close to 300,000 print and digital subscribers. ''The Boston Globe'' is the oldest and largest daily newspaper in Boston. Founded in 1872, the paper was mainly controlled by Irish Catholic interests before being sold to Charles H. Taylor and his family. After being privately held until 1973, it was sold to ''The New York Times'' in 1993 for $1.1billion, making it one of the most expensive print purchases in U.S. history. The newspaper was purchased in 2013 by Boston Red Sox and Liverpool owner John W. Henry for $70million from The New York Times Company, having lost over 90% of its value in 20 years. The newspaper has been noted as "one of the nation's most prestigious papers." In 1967, ''The Boston Globe'' became the first major paper in the U.S. to come out against the Vietnam War. The paper's 200 ...
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ScienceDaily
''Science Daily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. The site was founded by married couple Dan and Michele Hogan in 1995; Dan Hogan formerly worked in the public affairs department of Jackson Laboratory The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by a eugenicist. It employs more than 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, ... writing press releases. The site makes money from selling advertisements. As of 2010, the site said that it had grown "from a two-person operation to a full-fledged news business with worldwide contributors". At the time, it was run out of the Hogans' home, had no reporters, and only reprinted press releases. In 2012, Quantcast ranked it at 614 with 2.6 million U.S ...
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David Andrew Sinclair
David Andrew Sinclair (born June 26, 1969) is an Australian biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and is the co-director of its Paul F. Glenn Center for Biology of Aging Research. He is an officer of the Order of Australia (AO). Sinclair has appeared in ''Time'' magazine, ''The New York Times'', ''The Charlie Rose Show'', ''60 Minutes'', ''Boston'' magazine, ''The Washington Post'', ''The Economist'', TED and ''The Joe Rogan Experience''. Early life and education David Andrew Sinclair was born in Australia in 1969, and he grew up in St Ives, New South Wales. His paternal grandmother had emigrated to Australia following the suppression of the Hungarian Uprising of 1956, and his father changed the family name from Szigeti to Sinclair. Sinclair studied at the University of New South Wales, Sydney, obtaining a BSc in biochemistry with honours in 1991 and a Ph.D. in molecular genetics in ...
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Nicotinamide Adenine Dinucleotide
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine nucleobase and the other nicotinamide. NAD exists in two forms: an oxidized and reduced form, abbreviated as NAD and NADH (H for hydrogen), respectively. In metabolism, nicotinamide adenine dinucleotide is involved in redox reactions, carrying electrons from one reaction to another. The cofactor is, therefore, found in two forms in cells: NAD is an oxidizing agent – it accepts electrons from other molecules and becomes reduced. This reaction, also with H+, forms NADH, which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD. However, it is also used in other cellular processes, most notably as a substrate of enzymes in adding or removing chemical groups ...
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Epidermal Growth Factor Receptor
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). In many cancer types, mutations affecting EGFR expression or activity could result in cancer. Epidermal growth factor and its receptor was discovered by Stanley Cohen of Vanderbilt University. Cohen shared the 1986 Nobel Prize in Medicine with Rita Levi-Montalcini for their discovery of growth factors. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with the development of a wide variety of tumors. Interruption of EGFR signalling, either ...
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Boao
Bo'ao/Boao () is a town located next to the eastern coastal city of Qionghai in Hainan Province, People's Republic of China, near the mouth of the Wanquan River where it discharges into the South China Sea. The town is away from Qionghai, away from Haikou and away from Sanya. Bo'ao is famous for the Boao Forum for Asia, an international organisation whose venue is permanently located on Bo'ao's largest island, Dongyu Island (). Transportation Bo'ao railway station serves this town. Song about Bo'ao In 2018, French singer Dantès Dailiang and Chinese singer Eva release two songs in four languages (Chinese, Russian, French and English) and two music video clips about Bo'ao.Forever in Bo'ao, Dantès Dai Liang & Eva, https://www.youtube.com/watch?v=CyGZ-niz5f8 2018 See also *Boao Forum for Asia The Boao Forum for Asia (BFA; ), initiated by 25 Asian countries and Australia (increased to 28 in 2006), is a non-profit organisation that hosts high-level forums for leaders ...
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Evergrande
The China Evergrande Group is the second largest property developer in China by sales. It is ranked 122nd on the ''Fortune'' Global 500. It is incorporated in the Cayman Islands, a British Overseas Territory, and headquartered in the Houhai Financial Center in Nanshan District, Shenzhen, Guangdong Province, China. It was founded in 1996 by Xu Jiayin. It sells apartments mostly to upper- and middle-income dwellers. In 2018, it became the most valuable real estate company in the world. In 2021, the payments Evergrande had to make on its debt started the 2020–2022 Chinese property sector crisis; Evergrande's total debts were estimated in the hundreds of billions of dollars. This was one of the reasons for a drop in many stock market indices on September 20, 2021. At the end of 2021, the Chinese government was reportedly working to restructure Evergrande in order to resolve the crisis. The group also sought a moratorium on the early repayment option on one of its yuan-denom ...
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Elias Zerhouni
Elias Zerhouni (in Arabic إلياس زرهوني) (born April 12, 1951) is an Algerian-born American scientist, radiologist and biomedical engineer. He spent much of his career on the faculty of the Johns Hopkins University School of Medicine, serving as its executive vice-dean from 1995 to 2002. He was the 15th Director of the National Institutes of Health from May 2, 2002, to October 31, 2008, under the George W. Bush administration. In 2009, under the Obama administration he served as one of the country's first presidential science envoys to foster scientific and technologic collaboration with other nations. He also served as a senior fellow for the Bill and Melinda Gates Foundation from 2009 through 2010. From 2011 until his retirement in April 2018, he was the President for Global Research and Development at the pharmaceutical company Sanofi. Background A resident of Pasadena, Maryland, Zerhouni was born in Nedroma, Algeria. Having earned his M.D. degree at the Universi ...
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Gary Nabel
Gary J. Nabel is an American virologist and immunologist, and President and chief executive officer of ModeX Therapeutics in Natick, Massachusetts. Family Gary J. Nabel was born in Hartford, Connecticut and is married to Elizabeth Nabel. Their three children are all pursuing careers as physician-scientists. Education Nabel completed his undergraduate, M.D., and Ph.D. studies at Harvard University (1975, 1980, and 1982, respectively). He completed his dissertation research in the laboratory of immunologist Harvey Cantor and then worked as a postdoctoral fellow in the laboratory of David Baltimore at the Whitehead Institute, studying regulation of HIV gene expression by the recently discovered NF-κB, a host transcription factor. He completed his Internal Medicine residency at Brigham and Women’s Hospital. Career Gary J. Nabel, M.D., Ph.D. is a virologist and immunologist working on immune therapies and vaccines for cancer and infectious diseases. His scientific career has focu ...
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Biotechnology
Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used by Károly Ereky in 1919, meaning the production of products from raw materials with the aid of living organisms. Definition The concept of biotechnology encompasses a wide range of procedures for modifying living organisms according to human purposes, going back to domestication of animals, cultivation of the plants, and "improvements" to these through breeding programs that employ artificial selection and hybridization. Modern usage also includes genetic engineering as well as cell and tissue culture technologies. The American Chemical Society defines biotechnology as the application of biological organisms, systems, or processes by various industries to learning about the science of life and the improvement of the value of materi ...
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