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Gerstmann Syndrome
Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms that suggests the presence of a lesion usually near the junction of the temporal and parietal lobes at or near the angular gyrus. Gerstmann syndrome is typically associated with damage to the inferior parietal lobule of the dominant hemisphere. It is classically considered a left-hemisphere disorder, although right-hemisphere damage has also been associated with components of the syndrome. It is named after Jewish Austrian-born American neurologist Josef Gerstmann. Symptoms Gerstmann syndrome is characterized by four primary symptoms, collectively referred to as a tetrad: # Dysgraphia/agraphia: deficiency in the ability to write # Dyscalculia/acalculia: difficulty in learning or comprehending mathematics # Finger agnosia: inability to distinguish the fingers on the hand # Left-right disorientation Causes This disorder is often associated with brain lesions in the dominant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerstmann–Sträussler–Scheinker Syndrome
Gerstmann–Sträussler–Scheinker syndrome (GSS) is an extremely rare, usually familial, fatal neurodegenerative disease that affects patients from 20 to 60 years in age. It is exclusively heritable, and is found in only a few families all over the world. It is, however, classified with the transmissible spongiform encephalopathy, transmissible spongiform encephalopathies (TSE) due to the causative role played by PRNP, the human prion protein. GSS was first reported by the Austrian physicians Josef Gerstmann, Ernst Sträussler and Ilya Scheinker in 1936. Familial cases are associated with autosomal-dominant inheritance. Certain symptoms are common to GSS, such as progressive ataxia, pyramidal signs, and dementia; they worsen as the disease progresses. Symptoms and signs Symptoms start with slowly developing dysarthria (difficulty speaking) and cerebellar truncal ataxia (unsteadiness) and then the progressive dementia becomes more evident. Loss of memory can be the first sympt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dominant Hemisphere
The lateralization of brain function is the tendency for some neural functions or cognitive processes to be specialized to one side of the brain or the other. The median longitudinal fissure separates the human brain into two distinct cerebral hemispheres, connected by the corpus callosum. Although the macrostructure of the two hemispheres appears to be almost identical, different composition of neuronal networks allows for specialized function that is different in each hemisphere. Lateralization of brain structures is based on general trends expressed in healthy patients; however, there are numerous counterexamples to each generalization. Each human's brain develops differently, leading to unique lateralization in individuals. This is different from specialization, as lateralization refers only to the function of one structure divided between two hemispheres. Specialization is much easier to observe as a trend, since it has a stronger anthropological history. The best examp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aphasias
Aphasia is an inability to comprehend or formulate language because of damage to specific brain regions. The major causes are stroke and head trauma; prevalence is hard to determine but aphasia due to stroke is estimated to be 0.1–0.4% in the Global North. Aphasia can also be the result of brain tumors, brain infections, or neurodegenerative diseases (such as dementias). To be diagnosed with aphasia, a person's speech or language must be significantly impaired in one (or more) of the four aspects of communication following acquired brain injury. Alternatively, in the case of progressive aphasia, it must have significantly declined over a short period of time. The four aspects of communication are auditory comprehension, verbal expression, reading and writing, and functional communication. The difficulties of people with aphasia can range from occasional trouble finding words, to losing the ability to speak, read, or write; intelligence, however, is unaffected. Expressive lan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Specific Developmental Disorders
Specific developmental disorders (SDD) was a classification of disorders characterized by delayed development in one specific area or areas.Ahuja Vyas: ''Textbook of Postgraduate Psychiatry'' (2 Vols.), 2nd ed. 1999 Specific developmental disorders were contrasted to pervasive developmental disorders which were characterized by delays in the development of multiple basic functions including socialization and communication. ICD-10 taxonomy The tenth revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) has four categories of developmental disorders: specific developmental disorders of speech and language, specific developmental disorders of scholastic skills, specific developmental disorder of motor function, and mixed specific developmental disorder. DSM-III taxonomy In the third edition of the ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM-III),Dennis Cantwell & Lorian Baker: ''Developmental Speech and Language D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pure Alexia
Pure alexia, also known as agnosic alexia or alexia without agraphia or pure word blindness, is one form of alexia which makes up "the peripheral dyslexia" group. Individuals who have pure alexia have severe reading problems while other language-related skills such as naming, oral repetition, auditory comprehension or writing are typically intact. Pure alexia is also known as: "alexia without agraphia", "letter-by-letter dyslexia", "spelling dyslexia", or "word-form dyslexia". Another name for it is "Dejerine syndrome", after Joseph Jules Dejerine, who described it in 1892; however, when using this name, it should not be confused with medial medullary syndrome which shares the same eponym. Classification Pure alexia results from cerebral lesions in circumscribed brain regions and therefore belongs to the group of acquired reading disorders, alexia, as opposed to developmental dyslexia found in children who have difficulties in learning to read. Causes Pure alexia almost alway ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parietal Lobe
The parietal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The parietal lobe is positioned above the temporal lobe and behind the frontal lobe and central sulcus. The parietal lobe integrates sensory information among various modalities, including spatial sense and navigation (proprioception), the main sensory receptive area for the sense of touch in the somatosensory cortex which is just posterior to the central sulcus in the postcentral gyrus, and the dorsal stream of the visual system. The major sensory inputs from the skin ( touch, temperature, and pain receptors), relay through the thalamus to the parietal lobe. Several areas of the parietal lobe are important in language processing. The somatosensory cortex can be illustrated as a distorted figure – the cortical homunculus (Latin: "little man") in which the body parts are rendered according to how much of the somatosensory cortex is devoted to them. The superior parietal lobule a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Temporal Lobe
The temporal lobe is one of the four major lobes of the cerebral cortex in the brain of mammals. The temporal lobe is located beneath the lateral fissure on both cerebral hemispheres of the mammalian brain. The temporal lobe is involved in processing sensory input into derived meanings for the appropriate retention of visual memory, language comprehension, and emotion association. ''Temporal'' refers to the head's temples. Structure The temporal lobe consists of structures that are vital for declarative or long-term memory. Declarative (denotative) or explicit memory is conscious memory divided into semantic memory (facts) and episodic memory (events). Medial temporal lobe structures that are critical for long-term memory include the hippocampus, along with the surrounding hippocampal region consisting of the perirhinal, parahippocampal, and entorhinal neocortical regions. The hippocampus is critical for memory formation, and the surrounding medial temporal cortex is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of the mammalian cortex. The same Brodmann area number in different species does not necessarily indicate homologous areas. A similar, but more detailed cortical map was published by Constantin von Economo and Georg N. Koskinas in 1925. Present importance Brodmann areas have been discussed, debated, refined, and renamed exhaustively for nearly a century and remain the most w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Supramarginal Gyrus
The supramarginal gyrus is a portion of the parietal lobe. This area of the brain is also known as Brodmann area 40 based on the brain map created by Korbinian Brodmann to define the structures in the cerebral cortex. It is probably involved with language perception and processing, and lesions in it may cause receptive aphasia. Important functions The supramarginal gyrus is part of the somatosensory association cortex, which interprets tactile sensory data and is involved in perception of space and limbs location. It is also involved in identifying postures and gestures of other people and is thus a part of the mirror neuron system. The right-hemisphere supramarginal gyrus appears to play a central role in controlling empathy towards other people. When this structure is not working properly or when individuals have to make very quick judgements, empathy becomes severely limited. Research has shown that disrupting the neurons in the right supramarginal gyrus causes humans to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Finger Agnosia
Finger agnosia, first defined in 1924 by Josef Gerstmann, is the loss in the ability to distinguish, name, or recognize the fingers—not only the patient's own fingers, but also the fingers of others, and drawings and other representations of fingers. It is one of a tetrad of symptoms in Gerstmann syndrome, although it is also possible for finger agnosia to exist on its own without any other disorders. Usually, lesions to the left angular gyrus and posterior parietal areas can lead to finger agnosia. Causes Lesions to the left angular gyrus are associated with finger agnosia, as well as the other symptoms of Gerstmann Syndrome, also known as Angular Gyrus Syndrome. In a study by Rusconi et al., repetitive transcranial magnetic stimulation was used in healthy individuals to simulate finger agnosia. Stimulation to the intraparietal sulcus, supramarginal gyrus, as well as the left and right angular gyrus and posterior parietal areas caused difficulties in naming, recognizing, and d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dyscalculia
Dyscalculia () is a disability resulting in difficulty learning or comprehending arithmetic, such as difficulty in understanding numbers, learning how to manipulate numbers, performing mathematical calculations, and learning facts in mathematics. It is sometimes colloquially referred to "math dyslexia", though this analogy is misleading as they are distinct syndromes. Dyscalculia is associated with dysfunction in the region around the intraparietal sulcus and potentially also the frontal lobe. Dyscalculia does not reflect a general deficit in cognitive abilities or difficulties with time, measurement, and spatial reasoning. Estimates of the prevalence of dyscalculia range between 3 and 6% of the population. In 2015 it was established that 11% of children with dyscalculia also have ADHD. Dyscalculia has also been associated with Turner syndrome and people who have spina bifida. Mathematical disabilities can occur as the result of some types of brain injury, in which case the t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Josef Gerstmann
Josef Gerstmann (July 17, 1887, Lemberg – March 23, 1969, New York City) was a Jewish Austrian-born American neurologist. Gerstmann studied Medicine at the Medical University in Vienna, then capital of the Austro-Hungarian Empire, between 1906 and 1912 graduating in 1912. During World War I he served with distinction as the sanitary officer. Subsequently, he worked at the Clinic for Psychiatry-Neurology in Vienna with Wagner-Jauregg, and, after becoming Professor, he became the chief of Neurological Institute Maria-Theresien-Schlössel, Vienna in 1930. Being Jewish, he emigrated with his wife Martha to the United States in 1938, escaping the Nazi Anschluss The (, or , ), also known as the (, en, Annexation of Austria), was the annexation of the Federal State of Austria into the German Reich on 13 March 1938. The idea of an (a united Austria and Germany that would form a " Greater Germa .... Initially Gerstmann worked at the Springfield / Ohio State Hospital, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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