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Georg Ledderhose
Georg Ledderhose (15 December 1855, Bockenheim (Frankfurt am Main), Bockenheim, Regierungsbezirk Wiesbaden, Germany – 1 February 1925, Munich, Germany) was a German surgeon. Ledderhose studied in Strasbourg under Georg Albert Lücke (1829–1894), receiving his medical doctorate in 1880 and later working in Strasbourg hospital as a surgeon. He became ''Professor for Surgery'' in Strasbourg in 1891. He later worked in Munich, where he became honorary professor. In 1876, Ledderhose discovered glucosamine, glycosamine whilst working on cartilage with Felix Hoppe-Seyler, Ernst Felix Immanuel Hoppe-Seyler (1825–1895) in Strassburg. Although first identified by him, the stereochemistry of the compound was not fully defined until 1939 by the work of Walter Haworth. Ledderhose was the first to describe the condition of ''plantar fibromatosis'' in 1894, which was later known as Ledderhose's disease. References 1855 births 1925 deaths German surgeons {{germany-med-bio-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georg Ledderhose
Georg Ledderhose (15 December 1855, Bockenheim (Frankfurt am Main), Bockenheim, Regierungsbezirk Wiesbaden, Germany – 1 February 1925, Munich, Germany) was a German surgeon. Ledderhose studied in Strasbourg under Georg Albert Lücke (1829–1894), receiving his medical doctorate in 1880 and later working in Strasbourg hospital as a surgeon. He became ''Professor for Surgery'' in Strasbourg in 1891. He later worked in Munich, where he became honorary professor. In 1876, Ledderhose discovered glucosamine, glycosamine whilst working on cartilage with Felix Hoppe-Seyler, Ernst Felix Immanuel Hoppe-Seyler (1825–1895) in Strassburg. Although first identified by him, the stereochemistry of the compound was not fully defined until 1939 by the work of Walter Haworth. Ledderhose was the first to describe the condition of ''plantar fibromatosis'' in 1894, which was later known as Ledderhose's disease. References 1855 births 1925 deaths German surgeons {{germany-med-bio-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bockenheim (Frankfurt Am Main)
Bockenheim is a quarter of Frankfurt, Germany. It was incorporated into Frankfurt on 1 April 1895 and is part of the ''Ortsbezirk Innenstadt II''. Bockenheim lies west of central Frankfurt and is the third largest district by population in Frankfurt after Sachsenhausen and the Nordend with approximately 42,000 inhabitants. Bockenheim is bordered by the Goethe University, the Senckenberg museum and the Frankfurt Trade Fair in the south. The Bockenheimer Depot was the central tram depot, built around 1900, which is now a theatre, a venue of the Städtische Bühnen Frankfurt. Bockenheim also houses the headquarters of the Deutsche Bundesbank The Deutsche Bundesbank (), literally "German Federal Bank", is the central bank of the Federal Republic of Germany and as such part of the European System of Central Banks (ESCB). Due to its strength and former size, the Bundesbank is the most .... References Districts of Frankfurt {{Hesse-geo-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regierungsbezirk Wiesbaden
A ' () means "governmental district" and is a type of administrative division in Germany. Four of sixteen ' ( states of Germany) are split into '. Beneath these are rural and urban districts. Saxony has ' (directorate districts) with more responsibilities shifted from the state parliament. The cities of Bremen, Hamburg and Berlin – the city states – have a different system. ' serve as regional mid-level local government units in four of Germany's sixteen federal states: Baden-Württemberg, Bavaria, Hesse and North Rhine-Westphalia. Each of the nineteen ' features a non-legislative governing body called a ' (governing presidium) or ' (district government) headed by a ''Regierungspräsident'' (governing president), concerned mostly with administrative decisions on a local level for districts within its jurisdiction. Translations ' is a German term variously translated into English as "governmental district", "administrative district" or "province",Shapiro, Henry ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Munich
Munich ( ; german: München ; bar, Minga ) is the capital and most populous city of the States of Germany, German state of Bavaria. With a population of 1,558,395 inhabitants as of 31 July 2020, it is the List of cities in Germany by population, third-largest city in Germany, after Berlin and Hamburg, and thus the largest which does not constitute its own state, as well as the List of cities in the European Union by population within city limits, 11th-largest city in the European Union. The Munich Metropolitan Region, city's metropolitan region is home to 6 million people. Straddling the banks of the River Isar (a tributary of the Danube) north of the Northern Limestone Alps, Bavarian Alps, Munich is the seat of the Bavarian Regierungsbezirk, administrative region of Upper Bavaria, while being the population density, most densely populated municipality in Germany (4,500 people per km2). Munich is the second-largest city in the Bavarian dialects, Bavarian dialect area, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Strasbourg
Strasbourg (, , ; german: Straßburg ; gsw, label=Bas Rhin Alsatian, Strossburi , gsw, label=Haut Rhin Alsatian, Strossburig ) is the prefecture and largest city of the Grand Est region of eastern France and the official seat of the European Parliament. Located at the border with Germany in the historic region of Alsace, it is the prefecture of the Bas-Rhin department. In 2019, the city proper had 287,228 inhabitants and both the Eurométropole de Strasbourg (Greater Strasbourg) and the Arrondissement of Strasbourg had 505,272 inhabitants. Strasbourg's metropolitan area had a population of 846,450 in 2018, making it the eighth-largest metro area in France and home to 14% of the Grand Est region's inhabitants. The transnational Eurodistrict Strasbourg-Ortenau had a population of 958,421 inhabitants. Strasbourg is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg and Frankfurt), as it is the seat of several European insti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georg Albert Lücke
Georg Albert Lücke (4 June 1829 – 20 February 1894) was a German surgeon born in Magdeburg. He studied medicine at the Universities of Heidelberg, Göttingen and Halle, and following graduation traveled abroad to France, Italy and Algeria. After his return to Germany, he served as an assistant to Ernst Blasius (1802-1875) at Halle. In 1860 he became an assistant to Bernhard von Langenbeck (1810-1887) in Berlin, and from 1865 to 1872, he was a professor of surgery at the University of Bern. In 1872 he attained a similar position at the University of Strassburg. As a result of battle-related surgical experience during the Second Schleswig War, he published ''Kriegschirurgische aphorismen''. During the Franco-Prussian War, he was in charge of a hospital at Darmstadt, publishing ''Kriegschirurgische Fragen und Bemerkungen'' as a result. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glucosamine
Glucosamine (C6H13NO5) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids. Glucosamine is part of the structure of two polysaccharides, chitosan and chitin. Glucosamine is one of the most abundant monosaccharides. Produced commercially by the hydrolysis of shellfish exoskeletons or, less commonly, by fermentation of a grain such as corn or wheat, glucosamine has many names depending on country. Although a common dietary supplement, there is little evidence that it is effective for relief of arthritis or pain, and is not an approved prescription drug. Dietary supplement Oral glucosamine is a dietary supplement and is not a prescription drug. Glucosamine is marketed as a supplement to support the structure and function of joints, and the marketing is targeted to people with osteoarthritis. Commonly sold forms of glucosamine are glucosamine sulfate, glucosamine chondroitin, glucosamine hydrochloride, and ''N''-acetylglucos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Felix Hoppe-Seyler
Ernst Felix Immanuel Hoppe-Seyler (''né'' Felix Hoppe; 26 December 1825 – 10 August 1895) was a German physiologist and chemist, and the principal founder of the disciplines of biochemistry and molecular biology. Biography Hoppe-Seyler was born in Freyburg an der Unstrut in the Province of Saxony. He originally trained to be a physician in Halle and Leipzig, and received his medical doctorate from Berlin in 1851. Afterwards, he was an assistant to Rudolf Virchow at the Pathological Institute in Berlin. Hoppe-Seyler preferred scientific research to medicine, and later held positions in anatomy, applied chemistry, and physiological chemistry in Greifswald, Tübingen and Strasbourg. At Strasbourg, he was head of the department of biochemistry, the only such institution in Germany at the time. His work also led to advances in organic chemistry by his students and by immunologist Paul Ehrlich. Among his students and collaborators were Friedrich Miescher (1844–1895) and Nobel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stereochemistry
Stereochemistry, a subdiscipline of chemistry, involves the study of the relative spatial arrangement of atoms that form the structure of molecules and their manipulation. The study of stereochemistry focuses on the relationships between stereoisomers, which by definition have the same molecular formula and sequence of bonded atoms (constitution), but differ in structural formula (the three-dimensional orientations of their atoms in space). For this reason, it is also known as 3D chemistry—the prefix "stereo-" means "three-dimensionality". Stereochemistry spans the entire spectrum of organic, inorganic, biological, physical and especially supramolecular chemistry. Stereochemistry includes methods for determining and describing these relationships; the effect on the physical or biological properties these relationships impart upon the molecules in question, and the manner in which these relationships influence the reactivity of the molecules in question ( dynamic stereochemis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter Haworth
Sir Walter Norman Haworth Fellow of the Royal Society, FRS (19 March 1883 – 19 March 1950) was a British chemist best known for his groundbreaking work on ascorbic acid (vitamin C) while working at the University of Birmingham. He received the 1937 Nobel Prize in Chemistry "for his investigations on carbohydrates and vitamin C". The prize was shared with Swiss chemist Paul Karrer for his work on other vitamins. Haworth worked out the correct structure of a number of sugars, and is known among organic chemists for his development of the Haworth projection that translates three-dimensional sugar structures into convenient two-dimensional graphical form. Academic career Having worked for some time from the age of fourteen in the local Ryland's linoleum factory managed by his father, he studied for and successfully passed the entrance examination to the University of Manchester in 1903 to study chemistry. He made this pursuit in spite of active discouragement by his parents. He ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plantar
Standard anatomical terms of location are used to unambiguously describe the anatomy of animals, including humans. The terms, typically derived from Latin or Greek roots, describe something in its standard anatomical position. This position provides a definition of what is at the front ("anterior"), behind ("posterior") and so on. As part of defining and describing terms, the body is described through the use of anatomical planes and anatomical axes. The meaning of terms that are used can change depending on whether an organism is bipedal or quadrupedal. Additionally, for some animals such as invertebrates, some terms may not have any meaning at all; for example, an animal that is radially symmetrical will have no anterior surface, but can still have a description that a part is close to the middle ("proximal") or further from the middle ("distal"). International organisations have determined vocabularies that are often used as standard vocabularies for subdisciplines of anatomy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibromatosis
The term fibromatosis refers to a group of soft tissue tumors which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family. Diagnosis Subtypes Subtypes of fibromatosis include – * Juvenile fibromatosis * Fibromatosis colli: Benign sternocleidomastoid muscle tumor developing in infants within 8 weeks (average: 24 days) of delivery. It generally does not require resection and responds well to physiotherapy. * Infantile digital fibromatosis * Infantile myofibromatosis: Solitary tumors commonly occurring in the head and neck regions; multiple tumors occurring in the skin, subcutaneous tissue, muscles, and/or less commonly bones; or, rarely, tumors oc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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