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Guglielmi Detachable Coil
Endovascular coiling is an endovascular treatment for intracranial aneurysms and bleeding throughout the body. The procedure reduces blood circulation to the aneurysm through the use of microsurgical detachable platinum wires, with the clinician inserting one or more into the aneurysm until it is determined that blood flow is no longer occurring within the space. It is one of two main treatments for cerebral aneurysms, the other being surgical clipping. Clipping is an alternative to stenting for bleeding. Medical uses Endovascular coiling is used to treat cerebral aneurysms. The main goal is prevention of rupture in unruptured aneurysms, and prevention of rebleeding in ruptured aneurysms by limiting blood circulation to the aneurysm space. Clinically, packing density is recommended to be 20-30% or more of the aneurysm's volume, typically requiring deployment of multiple wires. Higher volumes may be difficult due to the delicate nature of the aneurysm; intraoperative rupture rates ...
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Interventional Neuroradiology
Endovascular therapy (EVT), also known as neurointerventional surgery (NIS), interventional neuroradiology (INR), endovascular neurosurgery, and interventional neurology is a medical subspecialty of radiology, neurosurgery, and neurology specializing in minimally invasive image-based technologies and procedures used in diagnosis and treatment of diseases of the head, neck, and spine. History Diagnostic angiography Cerebral angiography was developed by Portuguese neurologist Egas Moniz at the University of Lisbon, in order to identify central nervous system diseases such as tumors or arteriovenous malformations. He performed the first brain angiography in Lisbon in 1927 by injecting an iodinated contrast medium into the internal carotid artery and using the X-rays discovered 30 years earlier by Wilhelm Röntgen, Roentgen in order to visualize the cerebral vessels. In pre-CT and pre-MRI, it was the only tool to observe the structures within the skull and was also used to diagnose ...
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Interventional Radiology
Interventional radiology (IR) is a medical specialty that performs various minimally-invasive procedures using medical imaging guidance, such as x-ray fluoroscopy, computed tomography, magnetic resonance imaging, or ultrasound. IR performs both diagnostic and therapeutic procedures through very small incisions or body orifices. Diagnostic IR procedures are those intended to help make a diagnosis or guide further medical treatment, and include image-guided biopsy of a tumor or injection of an imaging contrast agent into a hollow structure, such as a blood vessel or a duct. By contrast, therapeutic IR procedures provide direct treatment—they include catheter-based medicine delivery, medical device placement (e.g., stents), and angioplasty of narrowed structures. The main benefits of interventional radiology techniques are that they can reach the deep structures of the body through a body orifice or tiny incision using small needles and wires. That decreases risks, pain, an ...
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Navier–Stokes Equations
In physics, the Navier–Stokes equations ( ) are partial differential equations which describe the motion of viscous fluid substances, named after French engineer and physicist Claude-Louis Navier and Anglo-Irish physicist and mathematician George Gabriel Stokes. They were developed over several decades of progressively building the theories, from 1822 (Navier) to 1842–1850 (Stokes). The Navier–Stokes equations mathematically express conservation of momentum and conservation of mass for Newtonian fluids. They are sometimes accompanied by an equation of state relating pressure, temperature and density. They arise from applying Isaac Newton's second law to fluid motion, together with the assumption that the stress in the fluid is the sum of a diffusing viscous term (proportional to the gradient of velocity) and a pressure term—hence describing ''viscous flow''. The difference between them and the closely related Euler equations is that Navier–Stokes equations take ...
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Computed Tomography Angiography
Computed tomography angiography (also called CT angiography or CTA) is a computed tomography technique used for angiography—the visualization of arteries and veins—throughout the human body. Using contrast injected into the blood vessels, images are created to look for blockages, aneurysms (dilations of walls), dissections (tearing of walls), and stenosis (narrowing of vessel). CTA can be used to visualize the vessels of the heart, the aorta and other large blood vessels, the lungs, the kidneys, the head and neck, and the arms and legs. CTA can also be used to localise arterial or venous bleed of the gastrointestinal system. Medical uses CTA can be used to examine blood vessels in many key areas of the body including the brain, kidneys, pelvis, and the lungs. Coronary CT angiography Coronary CT angiography (CCTA) is the use of CT angiography to assess the arteries of the heart. The patient receives an intravenous injection of contrast and then the heart is scanned using a ...
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In Silico
In biology and other experimental sciences, an ''in silico'' experiment is one performed on computer or via computer simulation. The phrase is pseudo-Latin for 'in silicon' (correct la, in silicio), referring to silicon in computer chips. It was coined in 1987 as an allusion to the Latin phrases , , and , which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature. History The earliest known use of the phrase was by Christopher Langton to describe artificial life, in the announcement of a workshop on that subject at the Center for Nonlinear Studies at the Los Alamos National Laboratory in 1987. The expression ''in silico'' was first used to characterize biological experiments carried out entirely in a computer in 1989, in the workshop "Cellular Automata: Theory and Applications" in Los Alamos, New Mexico, by Pedro Miramontes, a ma ...
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Finite Element Method
The finite element method (FEM) is a popular method for numerically solving differential equations arising in engineering and mathematical modeling. Typical problem areas of interest include the traditional fields of structural analysis, heat transfer, fluid flow, mass transport, and electromagnetic potential. The FEM is a general numerical method for solving partial differential equations in two or three space variables (i.e., some boundary value problems). To solve a problem, the FEM subdivides a large system into smaller, simpler parts that are called finite elements. This is achieved by a particular space discretization in the space dimensions, which is implemented by the construction of a mesh of the object: the numerical domain for the solution, which has a finite number of points. The finite element method formulation of a boundary value problem finally results in a system of algebraic equations. The method approximates the unknown function over the domain. The sim ...
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Computational Fluid Dynamics
Computational fluid dynamics (CFD) is a branch of fluid mechanics that uses numerical analysis and data structures to analyze and solve problems that involve fluid flows. Computers are used to perform the calculations required to simulate the free-stream flow of the fluid, and the interaction of the fluid ( liquids and gases) with surfaces defined by boundary conditions. With high-speed supercomputers, better solutions can be achieved, and are often required to solve the largest and most complex problems. Ongoing research yields software that improves the accuracy and speed of complex simulation scenarios such as transonic or turbulent flows. Initial validation of such software is typically performed using experimental apparatus such as wind tunnels. In addition, previously performed analytical or empirical analysis of a particular problem can be used for comparison. A final validation is often performed using full-scale testing, such as flight tests. CFD is applied to ...
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Circle Of Willis From CT Angio
A circle is a shape consisting of all points in a plane that are at a given distance from a given point, the centre. Equivalently, it is the curve traced out by a point that moves in a plane so that its distance from a given point is constant. The distance between any point of the circle and the centre is called the radius. Usually, the radius is required to be a positive number. A circle with r=0 (a single point) is a degenerate case. This article is about circles in Euclidean geometry, and, in particular, the Euclidean plane, except where otherwise noted. Specifically, a circle is a simple closed curve that divides the plane into two regions: an interior and an exterior. In everyday use, the term "circle" may be used interchangeably to refer to either the boundary of the figure, or to the whole figure including its interior; in strict technical usage, the circle is only the boundary and the whole figure is called a '' disc''. A circle may also be defined as a special kin ...
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Electrolysis
In chemistry and manufacturing, electrolysis is a technique that uses direct electric current (DC) to drive an otherwise non-spontaneous chemical reaction. Electrolysis is commercially important as a stage in the separation of elements from naturally occurring sources such as ores using an electrolytic cell. The voltage that is needed for electrolysis to occur is called the decomposition potential. The word "lysis" means to separate or break, so in terms, electrolysis would mean "breakdown via electricity". Etymology The word "electrolysis" was introduced by Michael Faraday in 1834, using the Greek words "amber", which since the 17th century was associated with electrical phenomena, and ' meaning "dissolution". Nevertheless, electrolysis, as a tool to study chemical reactions and obtain pure elements, precedes the coinage of the term and formal description by Faraday. History In the early nineteenth century, William Nicholson and Anthony Carlisle sought to further Volt ...
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Parent Artery
A parent artery is a medical term to describe an artery from which another artery originates. It can also refer to the artery in which an aneurysm An aneurysm is an outward bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. Aneurysms may be a result of a hereditary condition or an acquired disease. Aneurysms can also be a nidus (s ... has occurred. References {{Reflist Angiology ...
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Balloon Catheter
A balloon catheter is a type of "soft" catheter with an inflatable "balloon" at its tip which is used during a catheterization procedure to enlarge a narrow opening or passage within the Human body, body. The deflated balloon catheter is positioned, then inflated to perform the necessary procedure, and deflated again in order to be removed. Some common uses include: *angioplasty or balloon septostomy, via cardiac catheterization (heart cath) *tuboplasty via uterus, uterine catheterization *pyeloplasty using a detachable inflatable balloon stent positioned via a cystoscopy, cystocopic transvesicular approach. Angioplasty balloon catheters Balloon catheters used in angioplasty are either of Over-the-Wire (OTW) or Rapid Exchange (Rx) design. Rx catheters nowadays are about 90% of the Coronary Intervention market. While OTW Catheters may still be useful in highly tortuous vascular pathways, they sacrifice deflation time and pushability. When a balloon catheter is used to compress p ...
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