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GraphPad Prism
GraphPad Software Inc. was a privately held software development corporation until its acquisition by Insight Partners in 2017. The company was named Insightful Science, which itself merged with Dotmatics in 2021. The original software was written by Harvey Motulsky in 1989 and it was co-founded by Motulsky and Earl Beutler. The company operates in California. Its products include the 2D scientific graphing, biostatistics, curve fitting software GraphPad Prism and the free, web-based statistical calculation software, GraphPad QuickCalcs. GraphPad Prism GraphPad Prism is a commercial scientific 2D graphing and statistics software for Windows and Mac OS desktop computers. Software features include nonlinear regression In statistics, nonlinear regression is a form of regression analysis in which observational data are modeled by a function which is a nonlinear combination of the model parameters and depends on one or more independent variables. The data are fit ..., with f ...
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Insight Partners
Insight Partners (previously Insight Venture Partners) is an American venture capital and private equity firm based in New York City. The firm invests in growth-stage technology, software and Internet businesses. History Insight Partners was founded in 1995 by Jeff Horing and Jerry Murdock. Insight Partners raised more than $90 billion in capital commitments, including $20 billion in its Fund XII in 2021. In March 2019, Insight Venture Partners changed its name to Insight Partners. In October 2019, the firm established an office in Tel Aviv. In 2020, Insight Partners joined Diligent Corporation's initiative and pledged to create five new board roles among its portfolio companies for racially diverse candidates. In 2020, Insight Partners backed software startup JFrog's initial public offering (IPO), followed by 1stdibs' IPO in 2021. In April 2021, Insight Partners raised $1.56 billion for the Insight Partners Opportunities Fund I LP, a new fund outside of its flagship growth-inve ...
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Dotmatics
Dotmatics is an R&D scientific software company used by scientists in the R&D process that help them be more efficient in their efforts to innovate. Founded in 2005, the company's primary office is in Boston with 14 offices around the globe. In March 2021, Dotmatics joined forces with Insightful Science through a merger. In April 2022, the two companies consolidated under the Dotmatics brand. Dotmatics' software is used by 2 million scientists and researchers and 10,000 customers. Dotmatics offers a cloud-based data management platform to support the R&D process and a series of software applications used by scientists that includes GraphPad Prism, SnapGene, Geneious Prime, Geneious Biologics, Lab Archives, OMIQ, Protein Metrics, nQuery, Cytapex Bioinformatics, and De Novo. Dotmatics is backed by Insight Partners, a venture capital and private equity firm. History Dotmatics' origins trace back to Merck Sharp and Dohme, a multinational pharmaceutical company, where, in the early 20 ...
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Earl B
Earl () is a rank of the nobility in the United Kingdom. The title originates in the Old English word ''eorl'', meaning "a man of noble birth or rank". The word is cognate with the Scandinavian form ''jarl'', and meant "chieftain", particularly a chieftain set to rule a territory in a king's stead. After the Norman Conquest, it became the equivalent of the continental count (in England in the earlier period, it was more akin to a duke; in Scotland, it assimilated the concept of mormaer). Alternative names for the rank equivalent to "earl" or "count" in the nobility structure are used in other countries, such as the '' hakushaku'' (伯爵) of the post-restoration Japanese Imperial era. In modern Britain, an earl is a member of the peerage, ranking below a marquess and above a viscount. A feminine form of ''earl'' never developed; instead, ''countess'' is used. Etymology The term ''earl'' has been compared to the name of the Heruli, and to runic '' erilaz''. Proto-Norse ' ...
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Biostatistics
Biostatistics (also known as biometry) are the development and application of statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results. History Biostatistics and genetics Biostatistical modeling forms an important part of numerous modern biological theories. Genetics studies, since its beginning, used statistical concepts to understand observed experimental results. Some genetics scientists even contributed with statistical advances with the development of methods and tools. Gregor Mendel started the genetics studies investigating genetics segregation patterns in families of peas and used statistics to explain the collected data. In the early 1900s, after the rediscovery of Mendel's Mendelian inheritance work, there were gaps in understanding between genetics and evolutionary Darwinism. Francis Galton tried to expand Mendel's ...
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MacOS
macOS (; previously OS X and originally Mac OS X) is a Unix operating system developed and marketed by Apple Inc. since 2001. It is the primary operating system for Apple's Mac computers. Within the market of desktop and laptop computers it is the second most widely used desktop OS, after Microsoft Windows and ahead of ChromeOS. macOS succeeded the classic Mac OS, a Mac operating system with nine releases from 1984 to 1999. During this time, Apple cofounder Steve Jobs had left Apple and started another company, NeXT, developing the NeXTSTEP platform that would later be acquired by Apple to form the basis of macOS. The first desktop version, Mac OS X 10.0, was released in March 2001, with its first update, 10.1, arriving later that year. All releases from Mac OS X 10.5 Leopard and after are UNIX 03 certified, with an exception for OS X 10.7 Lion. Apple's other operating systems (iOS, iPadOS, watchOS, tvOS, audioOS) are derivatives of macOS. A promi ...
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Windows
Windows is a group of several proprietary graphical operating system families developed and marketed by Microsoft. Each family caters to a certain sector of the computing industry. For example, Windows NT for consumers, Windows Server for servers, and Windows IoT for embedded systems. Defunct Windows families include Windows 9x, Windows Mobile, and Windows Phone. The first version of Windows was released on November 20, 1985, as a graphical operating system shell for MS-DOS in response to the growing interest in graphical user interfaces (GUIs). Windows is the most popular desktop operating system in the world, with 75% market share , according to StatCounter. However, Windows is not the most used operating system when including both mobile and desktop OSes, due to Android's massive growth. , the most recent version of Windows is Windows 11 for consumer PCs and tablets, Windows 11 Enterprise for corporations, and Windows Server 2022 for servers. Genealogy By marketing ...
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Commercial Software
Commercial software, or seldom payware, is a computer software that is produced for sale or that serves commercial purposes. Commercial software can be proprietary software or free and open-source software. Background and challenge While software creation by programming is a time and labor-intensive process, comparable to the creation of physical goods, the reproduction, duplication and sharing of software as digital goods is in comparison disproportionately easy. No special machines or expensive additional resources are required, unlike almost all physical goods and products. Once a software is created it can be copied in infinite numbers, for almost zero cost, by anyone. This made commercialization of software for the mass market in the beginning of the computing era impossible. Unlike hardware, it was not seen as trade-able and commercialize-able good. Software was plainly shared for free (hacker culture) or distributed bundled with sold hardware, as part of the service t ...
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Proprietary Software
Proprietary software is software that is deemed within the free and open-source software to be non-free because its creator, publisher, or other rightsholder or rightsholder partner exercises a legal monopoly afforded by modern copyright and intellectual property law to exclude the recipient from freely sharing the software or modifying it, and—in some cases, as is the case with some patent-encumbered and EULA-bound software—from making use of the software on their own, thereby restricting his or her freedoms. It is often contrasted with open-source or free software. For this reason, it is also known as non-free software or closed-source software. Types Origin Until the late 1960s computers—large and expensive mainframe computers, machines in specially air-conditioned computer rooms—were usually leased to customers rather than sold. Service and all software available were usually supplied by manufacturers without separate charge until 1969. Computer vendors ...
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Statistics Software
Statistical software are specialized computer programs for analysis in statistics and econometrics. Open-source * ADaMSoft – a generalized statistical software with data mining algorithms and methods for data management * ADMB – a software suite for non-linear statistical modeling based on C++ which uses automatic differentiation * Chronux – for neurobiological time series data * DAP – free replacement for SAS * Environment for DeveLoping KDD-Applications Supported by Index-Structures (ELKI) a software framework for developing data mining algorithms in Java * Epi Info – statistical software for epidemiology developed by Centers for Disease Control and Prevention (CDC). Apache 2 licensed * Fityk – nonlinear regression software (GUI and command line) * GNU Octave – programming language very similar to MATLAB with statistical features * gretl – gnu regression, econometrics and time-series library * intrinsic Noise Analyzer (iNA) – For analyzing intrinsic fluctuati ...
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Nonlinear Regression
In statistics, nonlinear regression is a form of regression analysis in which observational data are modeled by a function which is a nonlinear combination of the model parameters and depends on one or more independent variables. The data are fitted by a method of successive approximations. General In nonlinear regression, a statistical model of the form, : \mathbf \sim f(\mathbf, \boldsymbol\beta) relates a vector of independent variables, \mathbf, and its associated observed dependent variables, \mathbf. The function f is nonlinear in the components of the vector of parameters \beta, but otherwise arbitrary. For example, the Michaelis–Menten model for enzyme kinetics has two parameters and one independent variable, related by f by: : f(x,\boldsymbol\beta)= \frac This function is nonlinear because it cannot be expressed as a linear combination of the two ''\beta''s. Systematic error may be present in the independent variables but its treatment is outside the scope of ...
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Software Companies Based In California
Software is a set of computer programs and associated documentation and data. This is in contrast to hardware, from which the system is built and which actually performs the work. At the lowest programming level, executable code consists of machine language instructions supported by an individual processor—typically a central processing unit (CPU) or a graphics processing unit (GPU). Machine language consists of groups of binary values signifying processor instructions that change the state of the computer from its preceding state. For example, an instruction may change the value stored in a particular storage location in the computer—an effect that is not directly observable to the user. An instruction may also invoke one of many input or output operations, for example displaying some text on a computer screen; causing state changes which should be visible to the user. The processor executes the instructions in the order they are provided, unless it is instructed ...
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Companies Based In San Diego
A company, abbreviated as co., is a legal entity representing an association of people, whether natural, legal or a mixture of both, with a specific objective. Company members share a common purpose and unite to achieve specific, declared goals. Companies take various forms, such as: * voluntary associations, which may include nonprofit organizations * business entities, whose aim is generating profit * financial entities and banks * programs or educational institutions A company can be created as a legal person so that the company itself has limited liability as members perform or fail to discharge their duty according to the publicly declared incorporation, or published policy. When a company closes, it may need to be liquidated to avoid further legal obligations. Companies may associate and collectively register themselves as new companies; the resulting entities are often known as corporate groups. Meanings and definitions A company can be defined as an "artificial per ...
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