Dotmatics is an R&D scientific software company used by scientists in the R&D process that help them be more efficient in their efforts to innovate. Founded in 2005, the company's primary office is in Boston with 14 offices around the globe. In March 2021, Dotmatics joined forces with Insightful Science through a merger.
In April 2022, the two companies consolidated under the Dotmatics brand.
Dotmatics' software is used by 2 million scientists and researchers and 10,000 customers.
Dotmatics offers a cloud-based data management platform to support the R&D process and a series of software applications used by scientists that includes GraphPad Prism, SnapGene, Geneious Prime, Geneious Biologics, Lab Archives, OMIQ, Protein Metrics, nQuery, Cytapex Bioinformatics, and De Novo. Dotmatics is backed by Insight Partners, a venture capital and private equity firm.
History
Dotmatics' origins trace back to
Merck Sharp and Dohme
Merck & Co., Inc. is an American multinational pharmaceutical company headquartered in Rahway, New Jersey, and is named for Merck Group, founded in Germany in 1668, of whom it was once the American arm. The company does business as Merck Sharp ...
, a multinational pharmaceutical company, where, in the early 2000s, Merck staff developed what later became Dotmatics' browser and gateway software. Dotmatics Limited was founded in 2005 as a spin-out when Merck closed the site. The company was established with the intent to address the information needs of scientists in the biotech/pharma space.
* Nov. 2006: Incorporate
Astex Therapeutics' chemical structure searching software as the product pinpoint.
* Oct. 2007: Headquarters moved to new premises in Bishops Stortford, United Kingdom.
* March 2009: Opened West Coast US office in Biotech Beach area of San Diego.
* Oct. 2009: Launched in Japanese market via Tokyo-based Infocom Corporation.
* April 2010: Opened East Coast US office in Boston Massachusetts.
* April 2010: Launched web-based Studies Notebook, for Windows, Mac, and Linux.
* Dec. 2010: Headquarters moved to expanded premises.
* March 2011, Studies Notebook integrated Lexichem chemical naming from
OpenEye Scientific Software
OpenEye Scientific Software is an American software company founded by Anthony Nicholls in 1997. It develops large-scale molecular modelling applications and toolkits. In July 2022, Cadence Design Systems agreed to acquire OpenEye for $500mi ...
, to automate name-to-structure and structure-to-name conversions in English and foreign languages.
* April 2011: Elemental web-based structure drawing tool included in
ChemSpider
ChemSpider is a database of chemicals. ChemSpider is owned by the Royal Society of Chemistry.
Database
The database contains information on more than 100 million molecules from over 270 data sources including:
* EPA DSSTox
* U.S. Food and Dr ...
, the
Royal Society of Chemistry
The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Ro ...
's community website.
* Sept. 2011: Move East Coast office from Boston's financial district to Woburn MA.
* Oct 2017: Significant investment by Scottish Equity Partners
* June 2020: BioBright acquired diversifying into Laboratory Automation technology.
* July 2020: 2019 Revenue is over £26M.
* March 2021: Insightful Science acquires Dotmatics;
Thomas Swalla named CEO.
* April 2022: Dotmatics used as the consolidated brand name of the combined Insightful Science and Dotmatics entity.
Software and use
Dotmatics develops web-based tools for querying, browsing, managing, and sharing scientific data and documents.
* Browser, a web-based tool for "chemically-aware" querying and browsing biological and chemical datasets, analysis of plate-based data, upload of data sets from
Microsoft Excel
Microsoft Excel is a spreadsheet developed by Microsoft for Microsoft Windows, Windows, macOS, Android (operating system), Android and iOS. It features calculation or computation capabilities, graphing tools, pivot tables, and a macro (comp ...
; and registration.
* Vortex for visualizing and data-mining biological and chemical information. Vortex provides structure-based searching, together with physiochemical property calculations.
* Pinpoint, an
Oracle
An oracle is a person or agency considered to provide wise and insightful counsel or prophetic predictions, most notably including precognition of the future, inspired by deities. As such, it is a form of divination.
Description
The word '' ...
-based tool for querying and integrating chemical databases.
* Gateway, a
document management system
A document management system (DMS) is usually a computerized system used to store, share, track and manage files or documents. Some systems include history tracking where a log of the various versions created and modified by different users is r ...
and collaboration tool.
* Nucleus, a web-based tool for importing, mapping, and storing data from existing sources.
* Register, a web-based tool for single and batch chemical compound registration.
* Bioregister, for registering biological entities (protein and nucleotide sequences), as well as their clone vector, purification and expression information.
* Studies is a screening data management tool that allows creation, capture, analysis, and storage of chemical, biological, and ad hoc research data.
* Studies notebook, a Web-based
Electronic lab notebook
An electronic lab notebook (also known as electronic laboratory notebook, or ELN) is a computer program designed to replace paper laboratory notebooks. Lab notebooks in general are used by scientists, engineers, and technicians to document resear ...
that supports chemistry, biology, and ad hoc research. It combines a web-based platform with
intellectual property
Intellectual property (IP) is a category of property that includes intangible creations of the human intellect. There are many types of intellectual property, and some countries recognize more than others. The best-known types are patents, cop ...
protection tools.
* Elemental, a web-based
structure drawing tool for drawing simple chemical structures or complex structure queries directly within a webpage. Also available as an iOS app.
* Cascade, a Web-based workflow management tool that controls workflow among different departments using the
Electronic lab notebook
An electronic lab notebook (also known as electronic laboratory notebook, or ELN) is a computer program designed to replace paper laboratory notebooks. Lab notebooks in general are used by scientists, engineers, and technicians to document resear ...
.
* Dotmatics for Office (D4O) makes Microsoft™ Office® applications such as Excel®, PowerPoint®, Word and Outlook® chemically aware.
* Chemselector manages very large chemistry datasets with fast search and trivially simple maintenance/update. It has a modern user interface focused on browsing and filtering for molecule, reagent and sample selection. The available eMolecules+ for Chemselector dataset provides access to highly curated eMolecules sourcing data.
* Inventory is a fully searchable sample and materials inventory that tracks chemicals, biologics, instruments and associated data across a hierarchy of locations and manages the dispensing and plating workflows, as samples are moved through an R&D process.
* Spaces allows project members within distributed research teams to collaborate using scientific teamboards that organize their research data and design ideas.
* Reaction Workflows, a graphical environment that enables scientists to build and execute data processing workflows to perform common cheminformatics tasks, such as library enumeration, structure normalization and compound profiling.
The Informatics Suite is all the software packaged into one integrated suite.
See also
*
Cheminformatics
Cheminformatics (also known as chemoinformatics) refers to use of physical chemistry theory with computer and information science techniques—so called "''in silico''" techniques—in application to a range of descriptive and prescriptive problem ...
*
Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...
*
Business intelligence tools Business intelligence software is a type of application software designed to retrieve, analyze, transform and report data for business intelligence. The applications generally read data that has been previously stored, often - though not necessaril ...
*
Electronic lab notebook
An electronic lab notebook (also known as electronic laboratory notebook, or ELN) is a computer program designed to replace paper laboratory notebooks. Lab notebooks in general are used by scientists, engineers, and technicians to document resear ...
*
Visual analytics
*
Life Sciences
This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, the ...
*
Laboratory informatics
Laboratory informatics is the specialized application of information technology aimed at optimizing and extending laboratory operations. It encompasses data acquisition (e.g. through sensors and hardware or voice), instrument interfacing, laborator ...
References
External links
*{{Official Website, dotmatics.com
Staff listing - LinkedIn
Cheminformatics