Glycoalkaloid
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Glycoalkaloid
Glycoalkaloids are a family of chemical compounds derived from alkaloids to which sugar groups are appended. Several are potentially toxic, most notably the poisons commonly found in the plant species ''Solanum dulcamara'' (bittersweet nightshade) and other plants in the genus ''Solanum'', including potato. A prototypical glycoalkaloid is solanine (composed of the sugar solanose and the alkaloid solanidine), which is found in the potato. The alkaloidal portion of the glycoalkaloid is also generically referred to as an aglycone. The intact glycoalkaloid is poorly absorbed from the human gastrointestinal tract, gastrointestinal tract but causes gastrointestinal irritation. The aglycone is absorbed and is believed to be responsible for observed nervous system signs. Glycoalkaloids are typically bitter (taste), bitter tasting, and produce a burning irritation in the back of the mouth and side of the tongue. The Aymara people of Bolivia use taste to detect the levels of glycoalkaloids ...
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Solanine Composition
Solanine is a glycoalkaloid poison found in species of the nightshade family within the genus ''Solanum'', such as the potato (''Solanum tuberosum''), the tomato (''Solanum lycopersicum''), and the eggplant (''Solanum melongena''). It can occur naturally in any part of the plant, including the leaves, fruit, and tubers. Solanine has pesticidal properties, and it is one of the plant's natural defenses. Solanine was first isolated in 1820 from the berries of the European black nightshade (''Solanum nigrum''), after which it was named. It belongs to the chemical family of saponins. Solanine poisoning Symptoms Solanine poisoning is primarily displayed by gastrointestinal and neurological disorders. Symptoms include nausea, diarrhea, vomiting, stomach cramps, burning of the throat, cardiac dysrhythmia, nightmares, headache, dizziness, itching, eczema, thyroid problems, and inflammation and pain in the joints. In more severe cases, hallucinations, loss of sensation, paralysis, f ...
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Solanine
Solanine is a glycoalkaloid poison found in species of the nightshade family within the genus ''Solanum'', such as the potato (''Solanum tuberosum''), the tomato (''Solanum lycopersicum''), and the eggplant (''Solanum melongena''). It can occur naturally in any part of the plant, including the leaves, fruit, and tubers. Solanine has pesticidal properties, and it is one of the plant's natural defenses. Solanine was first isolated in 1820 from the berries of the European black nightshade (''Solanum nigrum''), after which it was named. It belongs to the chemical family of saponins. Solanine poisoning Symptoms Solanine poisoning is primarily displayed by gastrointestinal and neurological disorders. Symptoms include nausea, diarrhea, vomiting, stomach cramps, burning of the throat, cardiac dysrhythmia, nightmares, headache, dizziness, itching, eczema, thyroid problems, and inflammation and pain in the joints. In more severe cases, hallucinations, loss of sensation, paralysis, ...
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Potato
The potato is a starchy food, a tuber of the plant ''Solanum tuberosum'' and is a root vegetable native to the Americas. The plant is a perennial in the nightshade family Solanaceae. Wild potato species can be found from the southern United States to southern Chile. The potato was originally believed to have been domesticated by Native Americans independently in multiple locations,University of Wisconsin-Madison, ''Finding rewrites the evolutionary history of the origin of potatoes'' (2005/ref> but later genetic studies traced a single origin, in the area of present-day southern Peru and extreme northwestern Bolivia. Potatoes were domesticated there approximately 7,000–10,000 years ago, from a species in the ''Solanum brevicaule'' complex. Lay summary: In the Andes region of South America, where the species is indigenous, some close relatives of the potato are cultivated. Potatoes were introduced to Europe from the Americas by the Spanish in the second half of the 16 ...
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Solanidine
Solanidine is a poisonous steroidal alkaloid chemical compound that occurs in plants of the family Solanaceae, such as potato and ''Solanum americanum''. Human ingestion of solanidine also occurs via the consumption of the glycoalkaloids, α-solanine and α-chaconine, present in potatoes.Kuiper-Goodman, T., Nawrot, P.S.Solanine and Chaconine IPCS Inchem The sugar portion of these glycoalkaloids hydrolyses in the body, leaving the solanidine portion. Solanidine occurs in the blood serum of normal healthy people who eat potato, and serum solanidine levels fall markedly once potato consumption ceases. Solanidine from food is also stored in the human body for prolonged periods of time, and it has been suggested that it could be released during times of metabolic stress with the potential for deleterious consequences. Solanidine is responsible for neuromuscular syndromes via cholinesterase inhibition.Everist, S.L., ''Poisonous Plants of Australia'', Angus and Robertson, 1974, . Uses ...
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Tongue
The tongue is a muscular organ (anatomy), organ in the mouth of a typical tetrapod. It manipulates food for mastication and swallowing as part of the digestive system, digestive process, and is the primary organ of taste. The tongue's upper surface (dorsum) is covered by taste buds housed in numerous lingual papillae. It is sensitive and kept moist by saliva and is richly supplied with nerves and blood vessels. The tongue also serves as a natural means of oral hygiene, cleaning the teeth. A major function of the tongue is the enabling of speech in humans and animal communication, vocalization in other animals. The human tongue is divided into two parts, an oral cavity, oral part at the front and a pharynx, pharyngeal part at the back. The left and right sides are also separated along most of its length by a vertical section of connective tissue, fibrous tissue (the lingual septum) that results in a groove, the median sulcus, on the tongue's surface. There are two groups of muscle ...
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Drug
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via insufflation (medicine), inhalation, drug injection, injection, smoking, ingestion, absorption (skin), absorption via a dermal patch, patch on the skin, suppository, or sublingual administration, dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to pharmacotherapy, treat, cure, preventive healthcare, prevent, or medical diagnosis, diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used ...
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Skin Cancer
Skin cancers are cancers that arise from the skin. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC). Basal-cell cancer grows slowly and can damage the tissue around it but is unlikely to spread to distant areas or result in death. It often appears as a painless raised area of skin that may be shiny with small blood vessels running over it or may present as a raised area with an ulcer. Squamous-cell skin cancer is more likely to spread. It usually presents as a hard lump with a scaly top but may also form an ulcer. Melanomas are the most aggressive. Signs include a mole that has changed in size, shape, color, has irregular edges, has more than one color, is itchy or bleeds. More than ...
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Pharmacotherapy
Pharmacotherapy is therapy using pharmaceutical drugs, as distinguished from therapy using surgery (surgical therapy), radiation (radiation therapy), movement ( physical therapy), or other modes. Among physicians, sometimes the term ''medical therapy'' refers specifically to pharmacotherapy as opposed to surgical or other therapy; for example, in oncology, medical oncology is thus distinguished from surgical oncology. Pharmacists are experts in pharmacotherapy and are responsible for ensuring the safe, appropriate, and economical use of pharmaceutical drugs. The skills required to function as a pharmacist require knowledge, training and experience in biomedical, pharmaceutical and clinical sciences. Pharmacology is the science that aims to continually improve pharmacotherapy. The pharmaceutical industry and academia use basic science, applied science, and translational science to create new pharmaceutical drugs. As pharmacotherapy specialists and pharmacists have responsibil ...
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Cultigens
A cultigen () or cultivated plant is a plant that has been deliberately altered or selected by humans; it is the result of artificial selection. These plants, for the most part, have commercial value in horticulture, agriculture or forestry. Because cultigens are defined by their mode of origin and not by where they are growing, plants meeting this definition remain cultigens whether they are naturalised in the wild, deliberately planted in the wild, or growing in cultivation. Cultigens arise in the following ways: * selections of variants from the wild or cultivation including vegetative sports (aberrant growth that can be reproduced reliably in cultivation) * plants that are the result of plant breeding and selection programs * genetically modified plants (plants modified by the deliberate implantation of genetic material) * graft-chimaeras (plants grafted to produce mixed tissue, the graft material possibly from wild plants, special selections, or hybrids). Naming Cultig ...
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Bolivia
, image_flag = Bandera de Bolivia (Estado).svg , flag_alt = Horizontal tricolor (red, yellow, and green from top to bottom) with the coat of arms of Bolivia in the center , flag_alt2 = 7 × 7 square patchwork with the (top left to bottom right) diagonals forming colored stripes (green, blue, purple, red, orange, yellow, white, green, blue, purple, red, orange, yellow, from top right to bottom left) , other_symbol = , other_symbol_type = Dual flag: , image_coat = Escudo de Bolivia.svg , national_anthem = " National Anthem of Bolivia" , image_map = BOL orthographic.svg , map_width = 220px , alt_map = , image_map2 = , alt_map2 = , map_caption = , capital = La Paz Sucre , largest_city = , official_languages = Spanish , languages_type = Co-official languages , languages ...
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Aymara People
Aymara may refer to: Languages and people * Aymaran languages, the second most widespread Andean language ** Aymara language, the main language within that family ** Central Aymara, the other surviving branch of the Aymara(n) family, which today includes only the endangered Jaqaru/Kawki language * Aymara people, the native ethnic group identified with the speakers of Altiplano Aymara Culture * ''Corazón Aymara'' (English: ''Aymara Heart''), 1925 Bolivian silent feature film directed by Pedro Sambarino * Grupo Aymara, Bolivian folk troupe of traditional music of pre-Hispanic and contemporary music of the Andes * Socialist Aymara Group (Spanish: ''Grupo Aymara Socialista''), left-wing indigenous political group in Bolivia Places * Aymaraes Province, the largest of seven provinces of the Apurímac Region in Peru * Aymara Lupaca Reserved Zone, a protected area in southeastern Peru Nature * ''Aymaramyia'', genus of crane bird found in Peru * ''Aymaratherium'', genus of extinct sloth ...
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Human Gastrointestinal Tract
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines. Food taken in through the mouth is digested to extract nutrients and absorb energy, and the waste expelled at the anus as feces. ''Gastrointestinal'' is an adjective meaning of or pertaining to the stomach and intestines. Most animals have a "through-gut" or complete digestive tract. Exceptions are more primitive ones: sponges have small pores ( ostia) throughout their body for digestion and a larger dorsal pore (osculum) for excretion, comb jellies have both a ventral mouth and dorsal anal pores, while cnidarians and acoels have a single pore for both digestion and excretion. The human gastrointestinal tract consists of the esophagus, stomach, and intestines, and is ...
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