George Ledlie Prize
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George Ledlie Prize
The George Ledlie Prize is awarded by the "President and Fellows of Harvard College" for contributions to science. George Ledlie George Hees Ledlie was born at Palatine Bridge, New York and attended private schools and colleges to prepare for Harvard, from where he graduated in 1884. In 1909 he reported to Harvard in a hand-written note that his full name had become George Ledlie – thus dropping his middle name Hees, the maiden name of his mother. Ledlie was a St. Louis and New York newspaper executive and an associate of publisher Joseph Pulitzer. George (Hees) Ledlie died on 16 April 1927, and the Harvard George Ledlie Prize became a bequest that year. As a philanthropist, Ledlie donated an amount to Harvard, with the following conditions: "Bequest of George Ledlie, 1884, the net income to be paid not oftener than once in every two years as a prize to a person in any way connected with said University, who, in the judgement of said University since the last awarding of the ...
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Palatine Bridge
Palatine Bridge is a Village (New York), village in Montgomery County, New York, Montgomery County, New York (state), New York, United States. The population was 737 at the 2010 census. The basis of the name is the community's location in a region settled by German Palatines, Palatine Germans. The Village of Palatine Bridge is in the Palatine, New York, Town of Palatine. The community is in the western part of the county, west of Amsterdam (city), New York, Amsterdam. History Palatine Bridge was settled in 1723. A bridge across the Mohawk River here built in 1798 gave the community its name. The village was incorporated in 1867. The Frey House, Palatine Bridge Freight House, and Webster Wagner House are listed on the National Register of Historic Places. In 2019 most of the developed portion of the village was listed on the Register as the Palatine Bridge Historic District. Geography Palatine Bridge is located at (42.910890, -74.574827). According to the United States Census ...
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Chlorophyll
Chlorophyll (also chlorophyl) is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words , ("pale green") and , ("leaf"). Chlorophyll allow plants to absorb energy from light. Chlorophylls absorb light most strongly in the blue portion of the electromagnetic spectrum as well as the red portion. Conversely, it is a poor absorber of green and near-green portions of the spectrum. Hence chlorophyll-containing tissues appear green because green light, diffusively reflected by structures like cell walls, is less absorbed. Two types of chlorophyll exist in the photosystems of green plants: chlorophyll ''a'' and ''b''. History Chlorophyll was first isolated and named by Joseph Bienaimé Caventou and Pierre Joseph Pelletier in 1817. The presence of magnesium in chlorophyll was discovered in 1906, and was that element's first detection in living tissue. After initial work done by German chemi ...
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Stem Cell Research
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However, when ...
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Douglas Melton
Douglas A. Melton is an American medical researcher who is the Harvard University Professor, Xander University Professor at Harvard University, and was an investigator at the Howard Hughes Medical Institute until 2022. Melton serves as the co-director of the Harvard Stem Cell Institute and was the first co-chairman (with David Scadden) of the Harvard University Department of Stem Cell and Regenerative Biology. Melton is the founder of several biotech companies including Gilead Sciences, Ontogeny (now Curis), iPierian (now True North Therapeutics ), and Semma Therapeutics. Melton holds membership in the National Academy of the Sciences, the American Academy of Arts and Sciences, and is a founding member of the International Society for Stem Cell Research.Michael J. Fox, Fox, Michael J. (May 3, 2007)"The 2007 Time 100: Douglas Melton" ''Time (magazine), Time''. Education Melton grew up in Blue Island, Illinois and completed a Bachelor of Science degree in biology at the University o ...
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Empiricism
In philosophy, empiricism is an epistemological theory that holds that knowledge or justification comes only or primarily from sensory experience. It is one of several views within epistemology, along with rationalism and skepticism. Empiricism emphasizes the central role of empirical evidence in the formation of ideas, rather than innate ideas or traditions. However, empiricists may argue that traditions (or customs) arise due to relations of previous sensory experiences. Historically, empiricism was associated with the "blank slate" concept (''tabula rasa''), according to which the human mind is "blank" at birth and develops its thoughts only through experience. Empiricism in the philosophy of science emphasizes evidence, especially as discovered in experiments. It is a fundamental part of the scientific method that all hypotheses and theories must be tested against observations of the natural world rather than resting solely on ''a priori'' reasoning, intuition, or r ...
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Aesthetics
Aesthetics, or esthetics, is a branch of philosophy that deals with the nature of beauty and taste, as well as the philosophy of art (its own area of philosophy that comes out of aesthetics). It examines aesthetic values, often expressed through judgments of taste. Aesthetics covers both natural and artificial sources of experiences and how we form a judgment about those sources. It considers what happens in our minds when we engage with objects or environments such as viewing visual art, listening to music, reading poetry, experiencing a play, watching a fashion show, movie, sports or even exploring various aspects of nature. The philosophy of art specifically studies how artists imagine, create, and perform works of art, as well as how people use, enjoy, and criticize art. Aesthetics considers why people like some works of art and not others, as well as how art can affect moods or even our beliefs. Both aesthetics and the philosophy of art try to find answers for what exact ...
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Methodology
In its most common sense, methodology is the study of research methods. However, the term can also refer to the methods themselves or to the philosophical discussion of associated background assumptions. A method is a structured procedure for bringing about a certain goal. In the context of research, this goal is usually to discover new knowledge or to verify pre-existing knowledge claims. This normally involves various steps, like choosing a sample, collecting data from this sample, and interpreting this data. The study of methods involves a detailed description and analysis of these processes. It includes evaluative aspects by comparing different methods to assess their advantages and disadvantages relative to different research goals and situations. This way, a methodology can help make the research process efficient and reliable by guiding researchers on which method to employ at each step. These descriptions and evaluations of methods often depend on philosophical background ...
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Social Science
Social science is one of the branches of science, devoted to the study of societies and the relationships among individuals within those societies. The term was formerly used to refer to the field of sociology, the original "science of society", established in the 19th century. In addition to sociology, it now encompasses a wide array of academic disciplines, including anthropology, archaeology, economics, human geography, linguistics, management science, communication science and political science. Positivist social scientists use methods resembling those of the natural sciences as tools for understanding society, and so define science in its stricter modern sense. Interpretivist social scientists, by contrast, may use social critique or symbolic interpretation rather than constructing empirically falsifiable theories, and thus treat science in its broader sense. In modern academic practice, researchers are often eclectic, using multiple methodologies (for instance, by ...
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Sara Lawrence-Lightfoot
Sara Lawrence-Lightfoot (born August 22, 1944) is an American sociologist who examines the culture of schools, the patterns and structures of classroom life, socialization within families and communities, and the relationships between culture and learning styles. She is the Emily Hargroves Fisher professor at the Harvard Graduate School of Education and a 1984 MacArthur Genius. Career Lawrence-Lightfoot has pioneered portraiture, an approach to social science methodology that bridges the realms of aesthetics and empiricism, which she continues to use in her own work. She has written 10 books, including ''I've Known Rivers'', which explores the development of creativity and wisdom using the lens of "human archaeology," ''The Art and Science of Portraiture'', which documents her pioneering approach to social science methodology, and ''The Third Chapter: Passion, Risk, and Adventure in the 25 Years After 50'' (2009). Her most recent book, ''Exit: The Endings That Set Us Free'', w ...
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Antimatter
In modern physics, antimatter is defined as matter composed of the antiparticles (or "partners") of the corresponding particles in "ordinary" matter. Antimatter occurs in natural processes like cosmic ray collisions and some types of radioactive decay, but only a tiny fraction of these have successfully been bound together in experiments to form antiatoms. Minuscule numbers of antiparticles can be generated at particle accelerators; however, total artificial production has been only a few nanograms. No macroscopic amount of antimatter has ever been assembled due to the extreme cost and difficulty of production and handling. Theoretically, a particle and its antiparticle (for example, a proton and an antiproton) have the same mass, but opposite electric charge, and other differences in quantum numbers. A collision between any particle and its anti-particle partner leads to their mutual annihilation, giving rise to various proportions of intense photons (gamma rays), neutrin ...
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Gerald Gabrielse
Gerald Gabrielse is an American physicist. He is the Board of Trustees Professor of Physics and Director of the Center for Fundamental Physics at Northwestern University, and Emeritus George Vasmer Leverett Professor of Physics at Harvard University. He is primarily known for his experiments trapping and investigating antimatter, measuring the electron g-factor, and measuring the electron electric dipole moment. He has been described as "a leader in super-precise measurements of fundamental particles and the study of anti-matter." Career Gabrielse attended Trinity Christian College and then Calvin College, graduating with a B.S. (honors) in 1973. He then completed his M.S. (1975) and Ph.D. (1980) in physics from the University of Chicago under Henry Gordon Berry. Gabrielse became a postdoc at the University of Washington in Seattle in 1978 under Hans Dehmelt, and joined the faculty in 1985. He became Professor of Physics at Harvard University in 1987, and the chair of the Ha ...
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Polio Virus
A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an RNA genome and a protein capsid. The genome is a single-stranded positive-sense RNA (+ssRNA) genome that is about 7500 nucleotides long. The viral particle is about 30 nm in diameter with icosahedral symmetry. Because of its short genome and its simple composition—only RNA and a nonenveloped icosahedral protein coat that encapsulates it—poliovirus is widely regarded as the simplest significant virus. Poliovirus was first isolated in 1909 by Karl Landsteiner and Erwin Popper. The structure of the virus was first elucidated in 1958 using X-ray diffraction by a team at Birkbeck College led by Rosalind Franklin, showing the polio virus to have icosahedral symmetry. In 1981, the poliovirus genome was published by two different tea ...
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